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1. 发明申请

WO2013038142A1 TOILET FLUSHING UNIT 审中-公开
标题翻译：厕所冲洗单元
公开(公告)号：WO2013038142A1
公开(公告)日：2013-03-21
申请号：PCT/GB2012/052103
申请日：2012-08-28
申请人： YOURTECH LIMITED , WARD, Keith , MOORE, Malcolm
发明人： WARD, Keith , MOORE, Malcolm
IPC分类号： E03D5/02 , E03D5/10 , E03D5/12
CPC分类号： E03D5/022 , E03D5/10 , E03D5/12
摘要： A toilet flushing unit including an actuator for operating a manually actuable toilet flushing device, a control system for operating the actuator after a predetermined amount of time has elapsed since a previous operation of the actuator.
摘要翻译：一种马桶冲洗单元，包括用于操作手动可动马桶冲洗装置的致动器，用于在从执行器的先前操作经过预定时间量之后操作致动器的控制系统。

2. 发明申请

WO2009111169A3 COMPOSITIONS COMPRISING PKC-DELTA MODULATORS AND METHODS FOR OCULAR NEUROPROTECTION 审中-公开
标题翻译：包含PKC-DELTA调节剂的组合物和用于眼部神经保护的方法
公开(公告)号：WO2009111169A3
公开(公告)日：2010-02-25
申请号：PCT/US2009034466
申请日：2009-02-19
申请人： BAUSCH & LOMB , WARD KEITH WAYNE , VENKATESH SRINI
发明人： WARD KEITH WAYNE , VENKATESH SRINI
IPC分类号： A61K31/343 , A61K38/00 , A61K38/08
CPC分类号： A61K31/343 , A61K38/168
摘要： Compositions for treating or controlling degeneration of at least a component of the human optic nerve system comprise a modulator of protein kinase Gdelta ('PKC-delta'). Such a PKC-delta modulator can be a compound that substantially inhibits, reduces, or interferes with, an activity of a cell signaling cascade involving PKC-delta or activation of PKC-delta. The compositions can also include an anti-inflammatory medicament. Such compositions can be administered to provide neuroprotection to a patient suffering from an ocular disease, such as glaucoma, AMD, DR, or retinitis pigmentosa.
摘要翻译：用于治疗或控制人视神经系统的至少一种成分的变性的组合物包含蛋白激酶Gdelta（'PKC-δ'）的调节剂。这种PKC-δ调节剂可以是基本上抑制，减少或干扰涉及PKC-δ或激活PKC-δ的细胞信号级联的活性的化合物。组合物还可以包括抗炎药物。可以施用这样的组合物以向患有眼部疾病如青光眼，AMD，DR或色素性视网膜炎的患者提供神经保护。

3. 发明申请

WO2008154129A1 PHARMACEUTICAL COMPOSITIONS AND METHOD FOR TREATING, REDUCING, AMELIORATING, ALLEVIATING, OR PREVENTING DRY EYE 审中-公开
标题翻译：药物组合物和治疗，减少，改善，改善或预防干眼症的方法
公开(公告)号：WO2008154129A1
公开(公告)日：2008-12-18
申请号：PCT/US2008/064231
申请日：2008-05-20
申请人： BAUSCH & LOMB INCORPORATED , ZHANG, Jinzhong , HU, Zhenze , WARD, Keith, Wayne
发明人： ZHANG, Jinzhong , HU, Zhenze , WARD, Keith, Wayne
IPC分类号： A61K31/00 , A61K38/13 , A61P27/02
CPC分类号： A61K31/155 , A61K31/00 , A61K31/4365 , A61K31/4709 , A61K31/517 , A61K38/13 , A61K45/06 , A61K2300/00
摘要： A composition for treating, reducing, ameliorating, alleviating, or preventing a dry eye condition or an ophthalmologic disorder that has an etiology in inflammation comprises an inhibitor of activity of poly(ADP-ribose) polymerase ("PARP"). The composition can also include a modulator of pro-inflammatory gene expression.
摘要翻译：用于治疗，减轻，改善，减轻或预防干眼症状或炎性病因的眼科疾病的组合物包含聚（ADP-核糖）聚合酶（“PARP”）的活性抑制剂。组合物还可以包括促炎基因表达的调节剂。

4. 发明申请

WO2012049450A1 RADAR SYSTEM 审中-公开
标题翻译：雷达系统
公开(公告)号：WO2012049450A1
公开(公告)日：2012-04-19
申请号：PCT/GB2011/001462
申请日：2011-10-10
申请人： TMD TECHNOLOGIES LIMITED , WARD, Keith Douglas
发明人： WARD, Keith Douglas
IPC分类号： G01S7/41 , G01S13/91 , G01S7/28
CPC分类号： G01S7/41 , G01S7/2813 , G01S7/292 , G01S7/412 , G01S7/414 , G01S7/415 , G01S13/52 , G01S13/5244 , G01S13/91 , H01Q3/2635 , H01Q3/267 , H01Q21/08
摘要： A component is disclosed for a radar system that comprises a main antenna operable to move azimuthally to sweep an area, a transmitter for transmitting pulses from the antenna and a receiver for receiving return signals. The component is operable to enable the radar system to detect a target in the presence of a wind turbine located in the area. The component comprises a plurality of - auxiliary antennas and a processor for processing the return signals, the processor being operable to generate a signature of the wind turbine from return signals received by the main and auxiliary antennas in a training process, to generate model data of a target or to receive model data of the target from memory, and to test returned data for the presence of a target, and, if a target is detected, to generate data representing a detected target. A method of detecting the position of a target in the presence of a wind turbine using the radar system is also described.
摘要翻译：公开了一种用于雷达系统的部件，其包括可操作以方位移动以扫描区域的主天线，用于从天线发送脉冲的发射器和用于接收返回信号的接收器。该部件可操作以使雷达系统能够在位于该区域中的风力涡轮机的存在下检测目标。该组件包括多个辅助天线和用于处理返回信号的处理器，所述处理器可操作以在训练过程中由主和辅助天线接收的返回信号产生风力涡轮机的签名，以产生模型数据目标或从存储器接收目标的模型数据，并且测试用于存在目标的返回数据，并且如果检测到目标，则生成表示检测到的目标的数据。还描述了使用雷达系统在存在风力涡轮机的情况下检测目标的位置的方法。

5. 发明申请

WO2012039887A1 COMPOSITION AND METHOD FOR PROMOTING WOUND HEALING 审中-公开
标题翻译：用于促进伤口愈合的组合物和方法
公开(公告)号：WO2012039887A1
公开(公告)日：2012-03-29
申请号：PCT/US2011/049266
申请日：2011-08-26
申请人： BAUSCH & LOMB INCORPORATED , ZHANG, Jinzhong , WARD, Keith, W. , LOPEZ, Francisco, J. , JONASSE, Matthew
发明人： ZHANG, Jinzhong , WARD, Keith, W. , LOPEZ, Francisco, J. , JONASSE, Matthew
IPC分类号： A61L15/58 , A61L26/00
CPC分类号： A61L15/58 , A61L26/008 , A61L2430/16
摘要： A composition for promoting wound healing comprises a bioadhesive polymer and a pharmaceutically acceptable liquid medium. Such a composition is applied to a wound to promote healing of the wound. The bioadhesive polymer can be selected from the group consisting of natural or synthetic hydrophilic polymers and hydrogels.
摘要翻译：用于促进伤口愈合的组合物包括生物粘附聚合物和药学上可接受的液体培养基。将这种组合物施用于伤口以促进伤口愈合。生物粘附聚合物可以选自天然或合成的亲水聚合物和水凝胶。

6. 发明申请

WO2008144347A8 COMBINATIONS COMPRISING A FLUOROQUINOLONE FOR TREATING, REDUCING, AMELIORATING, OR PREVENTING INFECTIONS 审中-公开
标题翻译：组合包含荧光素用于治疗，减少，改善或预防感染
公开(公告)号：WO2008144347A8
公开(公告)日：2010-02-25
申请号：PCT/US2008063624
申请日：2008-05-15
申请人： BAUSCH & LOMB , TYLE PRAVEEN , XIA ERNING , WANG HONGNA , NORTON SUSAN E , GUPTA PRAMOD KUMAR , WARD KEITH WAYNE , BRUNNER LYNNE
发明人： TYLE PRAVEEN , XIA ERNING , WANG HONGNA , NORTON SUSAN E , GUPTA PRAMOD KUMAR , WARD KEITH WAYNE , BRUNNER LYNNE
IPC分类号： A61K31/55 , A61P11/00 , A61P27/16 , A61P31/04
CPC分类号： A61K45/06 , A61K31/55 , A61K2300/00
摘要： Compositions for treating, reducing, ameliorating, or preventing infections comprise a fluoroquinolone having Formulae I-VIII and an additional anti-infective agent. Methods for treating, reducing, ameliorating, or preventing such infection use such compositions. Such compositions and methods can be effective against mixed types of pathogens including certain antibiotic-resistant microbial pathogens found in such infections.
摘要翻译：用于治疗，减少，改善或预防感染的组合物包含具有式I-VIII和另外的抗感染剂的氟喹诺酮。治疗，减轻，改善或预防这种感染的方法使用这种组合物。这种组合物和方法可以有效地对抗混合类型的病原体，包括在这种感染中发现的某些抗生素抗性微生物病原体。

7. 发明申请

WO2009089401A2 COMPOSITIONS COMPRISING TOLL-LIKE RECEPTOR OR CORECEPTOR ANTAGONISTS AND METHODS FOR TREATING OR CONTROLLING OCULAR ALLERGY USING SAME 审中-公开
标题翻译：包含TOLL-样受体或修饰物拮抗剂的组合物和用于治疗或控制使用其的OCALA ALLERGY的方法
公开(公告)号：WO2009089401A2
公开(公告)日：2009-07-16
申请号：PCT/US2009/030515
申请日：2009-01-09
申请人： BAUSCH & LOMB INCORPORATED , ZHANG, Jinzhong , WARD, Keith, Wayne , VO, Toan, P.
发明人： ZHANG, Jinzhong , WARD, Keith, Wayne , VO, Toan, P.
IPC分类号： A61K39/395
CPC分类号： C07K16/28 , A61K31/4706 , A61K31/473 , A61K2039/505 , C07K16/2896 , C12N15/117 , C12N2310/17
摘要： Compositions for treating or controlling ocular allergy comprise an antagonist to a toll-like receptor, a coreceptor thereof, or a combination thereof. The compositions can also include an anti-allergic medicament. The anti-allergic medicament can comprise an antihistamine, a mast-cell stabilizer, a leukotriene inhibitor, an immunomodulator, an anti-IgE agent, or a combination thereof. Such compositions can be used to treat or control seasonal allergic conjunctivitis, perennial allergic conjunctivitis, vernal keratoconjunctivitis, atopic keratoconjunctivitis, giant papillary conjunctivitis, toxic conjunctivitis, or contact ocular allergy.
摘要翻译：用于治疗或控制眼部过敏的组合物包括对长耳状受体的拮抗剂，其共同受体或其组合。组合物还可以包括抗过敏药物。抗过敏药物可以包含抗组胺剂，肥大细胞稳定剂，白三烯抑制剂，免疫调节剂，抗IgE剂或其组合。这些组合物可用于治疗或控制季节性过敏性结膜炎，常年性变应性结膜炎，春季角膜结膜炎，特应性角膜结膜炎，巨大乳头状结膜炎，中毒性结膜炎或接触性眼部过敏。

8. 发明申请

WO2009051992A1 COMPOSITIONS AND METHODS FOR TREATING DISEASES INVOLVING OCULAR ANGIOGENESIS BY INHIBITING ONE OR MORE SELECTED RECEPTOR TYROSINE KINASES 审中-公开
标题翻译：通过抑制一种或多种选择的受体类似蛋白激酶治疗涉及到角质形成的疾病的组合物和方法
公开(公告)号：WO2009051992A1
公开(公告)日：2009-04-23
申请号：PCT/US2008/079134
申请日：2008-10-08
申请人： BAUSCH & LOMB INCORPORATED , WARD, Keith, W.
发明人： WARD, Keith, W.
IPC分类号： A61K31/00 , A61K38/17 , A61P27/00 , A61K39/395 , A61K9/00
CPC分类号： C07K16/2863 , A61K31/00 , A61K31/7088
摘要： Compositions and methods are provided for the treatment of diseases involving ocular angiogenesis. The compositions and methods provide treatments for ocular angiogenic diseases such as diabetic macula edema, age-related macular degeneration, and diabetic retinopathy, by inhibiting one or more selected receptor tyrosine kinases, such as by inhibiting recepteur d'origine nantais (RON) or by inhibiting selected combinations of receptor tyrosine kinases such as RON, c-Met, Tie-2 and/or one or more VEGF receptors.
摘要翻译：提供组合物和方法用于治疗涉及眼血管生成的疾病。组合物和方法通过抑制一种或多种选择的受体酪氨酸激酶，例如通过抑制接受性鼻炎（RON）或通过抑制受体酪氨酸激酶（RON）或通过抑制受体酪氨酸激酶抑制受体酪氨酸激酶例如RON，c-Met，Tie-2和/或一种或多种VEGF受体的选择的组合。

9. 发明申请

WO2008021728A2 COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, OR AMELIORATING INFECTIONS AND SEQUELAE THEREOF 审中-公开
标题翻译：用于治疗，控制，减少或增加感染及其序列的组合物和方法
公开(公告)号：WO2008021728A2
公开(公告)日：2008-02-21
申请号：PCT/US2007/074936
申请日：2007-08-01
申请人： BAUSCH & LOMB INCORPORATED , HU, Zhenze , WARD, Keith, Wayne , PHILLIPS, Gary , KERPPOLA, Raili
发明人： HU, Zhenze , WARD, Keith, Wayne , PHILLIPS, Gary , KERPPOLA, Raili
IPC分类号： A61K31/4725 , A61K45/06 , A61P27/00 , A61P31/00 , A61P31/04 , A61P33/00
CPC分类号： A61K45/06 , A61K31/4709 , A61K31/4725 , A61K2300/00
摘要： A composition for treating, controlling, reducing, ameliorating, or alleviating infections and their inflammatory sequelae comprises a dissociated glucocorticoid receptor agonist ("DIGRA") and an anti-infective agent, such as an antibacterial, antiviral, antifungal, antiprotozoal agent, or a combination thereof. The composition can be formulated for topical application, injection, or implantation.
摘要翻译：用于治疗，控制，减少，改善或减轻感染及其炎症后遗症的组合物包括解离的糖皮质激素受体激动剂（“DIGRA”）和抗感染剂，例如抗细菌剂，抗病毒剂，抗真菌剂，抗原虫剂或的组合。该组合物可以配制用于局部施用，注射或植入。

10. 发明申请

WO2007130842A2 COMBINATION THERAPY FOR DISEASES INVOLVING ANGIOGENESIS 审中-公开
标题翻译：涉及血管生成疾病的联合治疗
公开(公告)号：WO2007130842A2
公开(公告)日：2007-11-15
申请号：PCT/US2007/067497
申请日：2007-04-26
申请人： BAUSCH & LOMB INCORPORATED , WARD, Keith, Wayne , TYLE, Praveen
发明人： WARD, Keith, Wayne , TYLE, Praveen
IPC分类号： A61P43/00 , A61K45/06
CPC分类号： A61K45/06
摘要： A composition useful for treating, preventing, or ameliorating a disease condition involving abnormal angiogenesis comprises at least two therapeutic agents selected from the group consisting of compounds that interact with and inhibit a downstream activity of extracellular VEGF, compounds that interact with at least a VEGF receptor and render it substantially unavailable for interacting with VEGF, and compounds that reduce a level of expression of VEGF. The invention also includes a method for treating, preventing, or ameliorating a disease condition involving abnormal angiogenesis using such a composition.
摘要翻译：用于治疗，预防或改善涉及异常血管发生的疾病状态的组合物包含至少两种治疗剂，其选自与细胞外VEGF相互作用并抑制下游活性的化合物，与至少一种VEGF受体相互作用的化合物并使其基本上不能与VEGF相互作用，以及降低VEGF表达水平的化合物。本发明还包括使用这种组合物治疗，预防或改善涉及异常血管发生的疾病状况的方法。

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