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    • 2. 发明申请
    • PROTECTED LITHIUM ELECTRODES FOR ELECTRO-TRANSPORT DRUG DELIVERY
    • 用于电输送药物递送的受保护的锂电极
    • WO2008067409A2
    • 2008-06-05
    • PCT/US2007/085802
    • 2007-11-28
    • POLYPLUS BATTERY COMPANYVISCO, Steven J.NIMON, Yevgeniy, S.
    • VISCO, Steven J.NIMON, Yevgeniy, S.
    • A61K33/00A61N1/30
    • A61K33/00A61K33/24A61N1/0436A61N1/044A61N1/0448A61N1/306
    • This invention provides new and novel devices and methods for administering lithium (Li) ions to a mammalian subject, especially the delivery of lithium (Li) ions to a body component for example across a body or tissue surface such as skin or a mucosal membrane, or for delivery of lithium ions directly to bodily fluids in a controllable and reproducible manner. In certain embodiments the device comprises a donor electrode that is a donor of a lithium ion; a protective architecture that is ionically conductive to the lithium ion, configured for application to a skin surface and positioned to isolate said donor electrode from the skin surface; and a counter electrode assembly configured for application to a skin surface, where said counter electrode assembly comprises a counter electrode operably coupled to said donor electrode.
    • 本发明提供了用于向哺乳动物对象施用锂(Li)离子的新型和新型装置和方法,特别是将锂(Li)离子递送至例如穿过身体或组织表面的身体组分 如皮肤或粘膜,或用于以可控和可重现的方式将锂离子直接递送至体液。 在某些实施方式中,该装置包括作为锂离子供体的供体电极; 离子导电至锂离子的保护性结构,被配置用于施加到皮肤表面并被定位成将所述供体电极与皮肤表面隔离; 以及配置用于施加到皮肤表面的对电极组件,其中所述对电极组件包括可操作地耦合到所述供体电极的对电极。
    • 3. 发明申请
    • PRECURSOR INFILTRATION AND COATING METHOD
    • 前驱物渗透和涂层方法
    • WO2006116153A3
    • 2007-09-20
    • PCT/US2006015196
    • 2006-04-21
    • UNIV CALIFORNIASHOLKLAPPER TAL ZJACOBSON CRAIG PVISCO STEVEN JDE JONGHE LUTGARD C
    • SHOLKLAPPER TAL ZJACOBSON CRAIG PVISCO STEVEN JDE JONGHE LUTGARD C
    • H01M4/00
    • H01M4/8621H01M4/8652H01M4/8885
    • A method of forming a composite (e.g., a mixed electrode) by infiltration of a porous structure (e.g., one formed from an ionically conductive material) with a solution of a precursor (e.g., for an electronically conductive material) results in a particulate layer on and within the porous structure with a single infiltration. The method involves forming a solution comprising at least one metal salt and a surfactant; heating the solution to substantially evaporate solvent and form a concentrated salt and surfactant solution; infiltrating the concentrated solution into a porous structure to create a composite; and heating the composite to substantially decompose the salt and surfactant to oxide and/or metal particles. The result is a particulate layer on the pore walls of the porous structure. In some instances the particulate layer is a continuous network. Corresponding devices have improved properties and performance.
    • 通过用前体(例如,用于电子导电材料)的溶液渗透多孔结构(例如由离子导电材料形成的多孔结构)形成复合材料(例如,混合电极)的方法导致颗粒层 在多孔结构内部和内部具有单次渗透。 该方法包括形成包含至少一种金属盐和表面活性剂的溶液; 加热溶液以使溶剂基本蒸发并形成浓盐和表面活性剂溶液; 将浓缩溶液渗透到多孔结构中以产生复合材料; 并加热复合物以将盐和表面活性剂基本上分解成氧化物和/或金属颗粒。 结果是多孔结构的孔壁上的颗粒层。 在某些情况下,颗粒层是连续的网络。 对应的设备具有改进的性能和性能。