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1. 发明申请

WO2005053546A3 OCCLUSION DEVICE FOR ASYMMETRICAL UTERINE ARTERY ANATOMY 审中-公开
标题翻译：非对称性子宫动脉解剖的装置
公开(公告)号：WO2005053546A3
公开(公告)日：2007-08-16
申请号：PCT/US2004038276
申请日：2004-11-16
申请人： VASCULAR CONTROL SYSTEMS INC , BURBANK FRED H , ALTIERI GREIG E , JONES MICHAEL L , OLSON ED
发明人： BURBANK FRED H , ALTIERI GREIG E , JONES MICHAEL L , OLSON ED
IPC分类号： A61B17/42 , A61B17/12 , A61B17/28
CPC分类号： A61B17/42 , A61B17/12 , A61B2017/2927 , A61B2017/2944 , A61B2017/4216 , A61B2017/4225
摘要： An occluding device is disclosed for occluding a female patient's uterine arteries which have unsymmetrical anatomy with respect to the patient's uterine cervix. The occluding device has a pair of pivotally connected occluding members, with at least one of the occluding member having a movable occluding element on a distal shaft section of the occluding member. The position and orientation of the occluding elements on the distal shaft sections may be adjusted by operative members on the proximal shaft sections of the occluding members to accommodate for asymmetrical uterine artery anatomy. The occluding elements have pressure applying surfaces with one or more blood flow sensors such as Doppler chips which help the physician to better identify the uterine artery and to monitor blood flow therein. A tenaculum-like guiding element configured to be secured within the patient's uterine cervix, may be provided to guide the occluding device to the patient's cervix.
摘要翻译：公开了一种闭塞装置，用于阻塞相对于患者的子宫颈具有不对称解剖结构的女性患者的子宫动脉。闭塞装置具有一对枢转连接的闭塞构件，其中至少一个阻塞构件在闭塞构件的远侧轴部上具有可移动的闭塞元件。闭合元件在远侧轴部分上的位置和取向可以通过闭塞构件的近侧轴部分上的操作构件来调整，以适应不对称的子宫动脉解剖。闭塞元件具有一个或多个血液流量传感器（例如多普勒碎片）的压力施加表面，其帮助医生更好地识别子宫动脉并监测其中的血液流动。被配置成固定在患者的子宫颈内的十字形引导元件可以设置成将闭塞装置引导到病人的子宫颈。

2. 发明申请

WO2004071275A2 VASCULAR CLAMP FOR CEASARIAN SECTION 审中-公开
标题翻译： CEASARIAN部分血管夹
公开(公告)号：WO2004071275A2
公开(公告)日：2004-08-26
申请号：PCT/US2004/003023
申请日：2004-02-03
申请人： VASCULAR CONTROL SYSTEMS, INC.
发明人： BURBANK, Fred, H. , JONES, Michael, L. , SERRA, R., J. , ALTIERI, Greig , UYENO, Jill
IPC分类号： A61B
CPC分类号： A61B17/122 , A61B5/026 , A61B5/489 , A61B8/06 , A61B8/12 , A61B2017/2825 , A61B2017/4216 , A61B2090/08021
摘要： The invention provides devices, systems and methods for clamping arteries which are useful in reducing or abolishing blood flow in an artery, and may be used to control hemorrhage flowing a caesarian delivery. A clamping device embodying features of the invention includes a pair of clamping members with opposed pressure-applying members having facing pressure-applying surfaces, at least one of which is a yieldable pressure-applying surface. The yieldable pressure-applying surface is preferably resilient. The clamping members are configured to adjust the distance between pressure-applying surfaces, and a blood flow sensor is disposed on at least one of the pressure-applying members to aid in locating the target artery and also to monitor blood flow through the artery. The clamping device is particularly suitable for occluding uterine arteries by compressing the broad ligament which contains the uterine artery and which is connected to the patient’s uterus with the arterial clamp.
摘要翻译：本发明提供用于夹紧动脉的装置，系统和方法，其可用于减少或消除动脉中的血流，并且可用于控制流出局部输送的出血。体现本发明特征的夹紧装置包括一对夹紧构件，其具有相对的施加压力的构件，其具有面对的压力施加表面，其中至少一个是可屈服的施加压力表面。可屈服的施加压力的表面优选是弹性的。夹紧构件被构造成调节压力施加表面之间的距离，并且血压传感器设置在至少一个压力施加构件上，以帮助定位目标动脉并且还监测通过动脉的血流。夹紧装置特别适用于通过压缩包含子宫动脉的宽韧带并用动脉夹连接到患者的子宫来闭塞子宫动脉。

3. 发明申请

WO2004069025A2 UTERINE ARTERY OCCLUSION CLAMP 审中-公开
标题翻译：子宫动脉闭塞钳
公开(公告)号：WO2004069025A2
公开(公告)日：2004-08-19
申请号：PCT/US2004001935
申请日：2004-01-23
申请人： VASCULAR CONTROL SYSTEMS INC
发明人： BURBANK FRED H , JONES MICHAEL L , ALTIERI GREIG E
IPC分类号： A61B17/00 , A61B17/28 , A61B17/42 , A61B19/00 , A61B
CPC分类号： A61B17/42 , A61B17/2812 , A61B2017/00057 , A61B2017/2837 , A61B2090/064 , A61B2090/378
摘要： The invention is directed to a uterine artery clamp and the relatively non-invasive treatment procedure utilizing this clamp. The uterine clamp includes a clamping member having a jaw with tissue-contacting surfaces for applying pressure to target tissue and a stabilizing member which is configured to be inserted into the patient's uterine cervical canal. The clamp may be provided with elongated handles to manually adjust the spacing between the jaw and stabilizer and thereby apply pressure to a uterine artery beneath a bundle of tissue held between the jaw and stabilizer. Uterine clamps embodying features of the invention by be used in procedures for treating uterine disorders such as fibroids, DUB, PPH and the like.
摘要翻译：本发明涉及一种子宫动脉钳和利用该钳的相对非侵入性治疗方法。子宫夹具包括具有钳口的夹持构件，所述钳口具有用于向目标组织施加压力的组织接触表面和构造成插入到患者子宫颈管中的稳定构件。夹具可以设置有细长的手柄，以手动调节钳口和稳定器之间的间隔，从而对保持在钳口和稳定器之间的组织束下面的子动脉施加压力。通过用于治疗子宫疾病如子宫肌瘤，DUB，PPH等的手术中使用体现本发明特征的子宫夹钳。

4. 发明申请

WO2004066818A3 TREATMENT FOR POST PARTUM HEMORRHAGE 审中-公开
公开(公告)号：WO2004066818A3
公开(公告)日：2004-08-12
申请号：PCT/US2004/001949
申请日：2004-01-23
申请人： VASCULAR CONTROL SYSTEMS, INC.
发明人： BURBANK, Fred, H. , JONES, Michael, L. , UYENO, Jill
IPC分类号： A61B17/44
摘要： The invention is directed to instruments and procedures using such instruments for temporarily reducing or terminating blood flow through a female patient's uterine artery to treat post partum hemorrhage (PPH). The uterine artery is occluded by a clamping device which includes a pair of pivotally connected clamping members (11, 12), with each of the clamping members having a handle (15, 17) and a clamping element (14, 16) at the distal end of the handle. The clamping elements are inclined with respect to the longitudinal axes of the handles at an included preferably between about 1300 and 1600. An artery locating sensor is provided on the distal end of at least obtuse angle between about 1200 and about 1700, one of the clamping elements. Preferably, the artery locating sensor is a Doppler ultrasound blood flow sensor. After birth, the clamping device is inserted into the female patient's post partum vaginal canal and advanced therein until one of the clamping elements is in the patient's uterine cervix and the other clamping element is on the exterior of the uterine cervix. The clamping element on the exterior of the patient's uterine cervix is pressed against the patient's vaginal fornix and the clamping device closed so as to occlude the uterine artery disposed within tissue grasped by the clamping device. The clamping device is locked in the closed configuration and maintained in the condition until the patient's uterus is sufficiently clotted up to ensure termination of the hemorrhaging, typically about 5 minutes to about 7 hours.

5. 发明申请

WO2004066818A2 TREATMENT FOR POST PARTUM HEMORRHAGE 审中-公开
标题翻译：治疗后痔疮
公开(公告)号：WO2004066818A2
公开(公告)日：2004-08-12
申请号：PCT/US2004001949
申请日：2004-01-23
申请人： VASCULAR CONTROL SYSTEMS INC
发明人： BURBANK FRED H , JONES MICHAEL L , UYENO JILL
IPC分类号： A61B17/00 , A61B17/28 , A61B17/42 , A61B19/00 , A61B
CPC分类号： A61B17/12 , A61B17/2812 , A61B17/42 , A61B2017/00057 , A61B2017/2837 , A61B2090/064 , A61B2090/378
摘要： The invention is directed to instruments and procedures using such instruments for temporarily reducing or terminating blood flow through a female patient's uterine artery to treat post partum hemorrhage (PPH). The uterine artery is occluded by a clamping device which includes a pair of pivotally connected clamping members, with each of the clamping members having a handle and a clamping element at the distal end of the handle. The clamping elements are inclined with respect to the longitudinal axes of the handles at an included obtuse angle between about 1200 and about 170°, preferably between about 130° and 160°. An artery locating sensor is provided on the distal end of at least one of the clamping elements. Preferably, the artery locating sensor is a Doppler ultrasound blood flow sensor. After birth, the clamping device is inserted into the female patient's post partum vaginal canal and advanced therein until one of the clamping elements Is in the patient's uterine cervix and the other clamping element is on the exterior of the uterine cervix. The clamping element on the exterior of the patient's uterine cervix is pressed against the patient's vaginal fornix and the clamping device closed so as to occlude the uterine artery disposed within tissue grasped by the clamping device. The clamping device is locked in the closed configuration and maintained in the condition until the patient's uterus is sufficiently clotted up to ensure termination of the hemorrhaging, typically about 5 minutes to about 7 hours.
摘要翻译：本发明涉及使用这种器械临时减少或终止通过女性患者子宫动脉的血液流动以治疗产后出血（PPH）的仪器和程序。子宫动脉被包括一对枢转连接的夹紧构件的夹紧装置封闭，其中每个夹紧构件具有手柄和在手柄的远端处的夹紧元件。夹紧元件相对于把手的纵向轴线以约1200至约170°，优选地在约130°至160°之间的包含的钝角倾斜。动脉定位传感器设置在至少一个夹紧元件的远端上。优选地，动脉定位传感器是多普勒超声血流传感器。出生后，将夹紧装置插入雌性患者的产后阴道管中并推进到其中，直到其中一个夹紧元件位于患者的子宫颈中，而另一个夹紧元件位于子宫颈的外部。患者子宫颈外侧的夹紧元件被压靠在患者的阴道穹窿上，并且夹紧装置关闭，从而封闭设置在由夹紧装置抓握的组织内的子宫动脉。夹紧装置被锁定在闭合构型中并保持在状态，直到患者的子宫充分凝结，以确保终止出血，通常约5分钟至约7小时。

6. 发明申请

WO2004045430A3 TENACULUM-LIKE DEVICE FOR INTRAVAGINAL OPERATIONS 审中-公开
公开(公告)号：WO2004045430A3
公开(公告)日：2004-06-03
申请号：PCT/US2003/037028
申请日：2003-11-18
申请人： VASCULAR CONTROL SYSTEMS, INC.
发明人： BURBANK, Fred, H. , JONES, Michael, L. , ALTIERI, Greig, E. , SERRA, R., J. , OLSON, Ed , WONG, Yu-Tung
IPC分类号： A61B17/42
摘要： The invention is directed to tenaculum-like devices and systems for the intravaginal delivery of therapeutic or diagnostic devices and particularly for occluding a female patient’s uterine arteries in order to treat uterine disorders. Included are methods for grasping, manipulating and retaining tissue. The tenaculum-type device has a distal portion with a sound configurer to enter a cervical os without causing undue trauma or discomfort to the patient, and a retention or tissue grasping mechanism with a grasping element such as a spike configured to engage and retain a patient’s cervix. The tenaculum-type devices embodying features of the invention may have an expandable distal tip to more securely be engaged within the patient’s uterine cervical canal.

7. 发明申请

WO2004045430A2 TENACULUM-LIKE DEVICE FOR INTRAVAGINAL INSTRUMENT DELIVERY 审中-公开
标题翻译：用于内窥镜仪器输送的类似器具
公开(公告)号：WO2004045430A2
公开(公告)日：2004-06-03
申请号：PCT/US0337028
申请日：2003-11-18
申请人： VASCULAR CONTROL SYSTEMS INC
发明人： BURBANK FRED H , JONES MICHAEL L , ALTIERI GREIG E , SERRA R J , OLSON ED , WONG YU-TUNG
IPC分类号： A61B17/28 , A61B17/42
CPC分类号： A61B17/4241 , A61B17/282 , A61B17/42
摘要： The invention is directed to tenaculum-like devices and systems for the intravaginal delivery of therapeutic or diagnostic devices and particularly for occluding a female patient's uterine arteries in order to treat uterine disorders. Included are methods for grasping, manipulating and retaining tissue. The tenaculum-type device has a distal portion with a sound configurer to enter a cervical os without causing undue trauma or discomfort to the patient, and a retention or tissue grasping mechanism with a grasping element such as a spike configured to engage and retain a patient's cervix. The tenaculum-type devices embodying features of the invention may have an expandable distal tip to more securely be engaged within the patient's uterine cervical canal.
摘要翻译：本发明涉及用于治疗或诊断装置的阴道内输送的特定用途的器械和系统，特别是用于阻塞女性患者的子宫动脉以治疗子宫疾病。包括用于抓握，操纵和保持组织的方法。所述牵引式装置具有远端部分，具有进入宫颈口的声音配置器，而不会对患者造成不适当的创伤或不适;以及保持或组织抓握机构，其具有诸如钉的抓握元件，其被构造成接合并保持患者的宫颈。体现本发明的特征的憩室型装置可以具有可扩张的远端，以更可靠地接合在患者的子宫颈管内。

8. 发明申请

WO02078549A3 METHOD AND APPARATUS FOR THE DETECTION AND LIGATION OF UTERINE ARTERIES 审中-公开
标题翻译：用于检测和定位子宫动物的方法和装置
公开(公告)号：WO02078549A3
公开(公告)日：2003-01-03
申请号：PCT/US0209775
申请日：2002-03-27
申请人： VASCULAR CONTROL SYSTEMS INC , BURBANK FRED H , JONES MIKE , SERRA R J , ALTIERI GREIG , UYENO JILL , WONG YU-TUNG , WERNETH RANDY
发明人： BURBANK FRED H , JONES MIKE , SERRA R J , ALTIERI GREIG , UYENO JILL , WONG YU-TUNG , WERNETH RANDY
IPC分类号： A61B17/12 , A61B5/026 , A61B8/06 , A61B17/00 , A61B17/122 , A61B17/128 , A61B17/42 , A61B18/00 , A61M25/00
CPC分类号： A61B17/12 , A61B5/026 , A61B5/415 , A61B5/418 , A61B8/06 , A61B8/12 , A61B17/00234 , A61B17/122 , A61B17/128 , A61B17/1285 , A61B17/2812 , A61B17/42 , A61B2017/0046 , A61B2017/4216
摘要： The invention provides devices, systems and methods for occluding arteries without puncturing skin or vessel walls. The devices, systems and methods for occluding arteries are configured to be applied to arteries externally of the arteries. Occlusion may be temporary or permanent, and may be partial or complete. Clamping a device to tissue near to an artery is effective to compress tissue around the artery and to indirectly compress the artery. The methods, devices and systems of the invention find use in, for example, treatment of uterine disorders and conditions which may be treated by occlusion of the uterine arteries. A uterine artery may be access via a patient's vagina by compressing a portion of the vaginal wall around a portion of a uterine artery to occlude a uterine artery. Clamping of an artery may also be performed by clamping a device directly onto an artery.
摘要翻译：本发明提供用于闭塞动脉而不刺穿皮肤或血管壁的装置，系统和方法。用于闭塞动脉的装置，系统和方法被配置为施加到动脉外部的动脉。闭塞可能是暂时的或永久的，可能是部分或完全的。将装置夹紧到靠近动脉的组织是有效的压缩动脉周围的组织并间接压缩动脉。本发明的方法，装置和系统可用于例如治疗可能通过闭塞子宫动脉治疗的子宫疾病和病症。通过将子宫动脉的一部分周围的一部分阴道壁压缩以阻塞子宫动脉，可以通过患者的阴道进入子宫动脉。也可以通过将装置直接夹在动脉上来进行动脉的夹紧。

9. 发明申请

WO2004045420A3 OCCLUSION DEVICE WITH DEPLOYABLE PADDLES FOR DETECTION AND OCCLUSION OF BLOOD VESSELS 审中-公开
公开(公告)号：WO2004045420A3
公开(公告)日：2004-06-03
申请号：PCT/US2003/035815
申请日：2003-11-11
申请人： VASCULAR CONTROL SYSTEMS, INC.
发明人： BURBANK, Fred, H. , JONES, Michael, L. , ALTIERI, Greig, E. , SERRA, R., J.
IPC分类号： A61B17/42
摘要： Devices, systems and methods for temporarily reducing or abolishing blood flow by occluding blood vessels are provided. A blood vessel-occlusion device embodying features of the invention includes a deployable pressure-applying member with a location sensor, and an applicator. The location sensor is configured to detect a blood vessel, which may be occluded by compression from the pressure-applying member. A pressure-applying member may be released from the applicator, with blood-vessel compression maintained after release. The applicator is configured to engage a guide, such as a tenaculum, to aid in the placement and operation of the applicator. A pressure-applying member may also engage the guide. The invention finds use in, for example, treating uterine disorders and conditions which may be treated by occlusion of the uterine arteries, such as uterine fibroids, dysfunctional uterine bleeding, post-partum hemorrhage, and bleeding associated with caesarian section.

10. 发明申请

WO0239905A9 DOPPLER DIRECTED SUTURE LIGATION DEVICE AND METHOD 审中-公开
标题翻译：多普勒方向定位设备和方法
公开(公告)号：WO0239905A9
公开(公告)日：2003-03-27
申请号：PCT/US0127792
申请日：2001-11-01
申请人： VASCULAR CONTROL SYSTEMS INC , BURBANK FRED , JONES MICHAEL L , UYENO JILL , ALTIERI GREIG E , SERRA R J
发明人： BURBANK FRED , JONES MICHAEL L , UYENO JILL , ALTIERI GREIG E , SERRA R J
IPC分类号： A61B17/00 , A61B17/04 , A61B17/12 , A61B17/30 , A61B17/32 , A61B18/00 , A61B18/14 , A61B19/00
CPC分类号： A61B17/32056 , A61B17/0469 , A61B17/0482 , A61B17/12009 , A61B18/1477 , A61B18/1482 , A61B2017/00349 , A61B2017/00867 , A61B2017/0472 , A61B2017/06104 , A61B2018/00601 , A61B2018/0063 , A61B2018/126 , A61B2018/1425 , A61B2090/378
摘要： A ligation device (100) includes a cannula (104) having first and second extendable members (120, 122) and a Doppler wand (140). The Doppler wand (140) permits an anatomical vessel, such as a blood vessel, to be located in close proximity to the distal end of the cannula (104). The extendable members (120, 122) are extendable on two opposite sides of the vessel. A length of ligation material, such as suture material, extends through the first extendable member and is attached to a detachable element (124) mounted to the distal most end of the extendable member. The second extendable member (122) includes a snare (126). The first extendable member (120) includes curved portions which, when the member (120) is extended distally, extend the detachable element (124) into position for the snare (126) so that the snare (126) can grab the loop. Once ensnared, the detachable element (124) is released from the first extendable member (120), which pulls the ligation material around the vessel. The ligation device (100) does not require prior visualization or dissection of the area around the vessel.
摘要翻译：连接装置（100）包括具有第一和第二可延伸构件（120,122）和多普勒杆（140）的套管（104）。多普勒棒（140）允许诸如血管的解剖血管位于紧邻套管（104）的远端附近。可延伸构件（120,122）可在容器的两个相对侧上延伸。连接材料（例如缝合材料）的长度延伸穿过第一可延伸构件并且附接到安装到可延伸构件的最远端的可拆卸元件（124）。第二可延伸构件（122）包括圈套（126）。第一可延伸构件（120）包括弯曲部分，当构件（120）向远侧延伸时，该部分将可拆卸元件（124）延伸到圈套（126）的位置，使得圈套（126）能抓住环路。一旦被捕获，可拆卸元件（124）从第一可延伸构件（120）释放，其将结扎材料拉回容器周围。结扎装置（100）不需要事先观察或解剖血管周围区域。

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