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1. 发明申请

WO0147372A3 ABSORBING FAT CHITOSAN 审中-公开
标题翻译：吸收脂肪的CHITOSAN
公开(公告)号：WO0147372A3
公开(公告)日：2001-12-27
申请号：PCT/US0034604
申请日：2000-12-15
申请人： VANSON INC , NICHOLS EVERETT J
发明人： NICHOLS EVERETT J
IPC分类号： A23L29/275 , A61K47/48 , C08B37/08 , C08L5/08 , A23L1/056 , C08B37/00
CPC分类号： C08B37/003 , A23L29/275 , A61K47/61 , A61K47/69 , C08L5/08
摘要： In one aspect, the present invention provides kits for reducing absorption of lipids by the gastrointestinal tract of a mammalian body. The kits include chitosan, packaging, and instructions indicating that the chitosan may be consumed with food. Chitosan useful for incorporation into kits of the present invention dissolves sufficiently rapidly in gastric juice that it does not have to be consumed in advance of a meal in order to dissolve within the stomach and thereafter effectively entrap lipids in the gastrointestinal tract of the consumer. In a particular embodiment of the kits of the present invention, the chitosan possesses the property of dissolving in a 100-fold (w/w) excess of 0.16N hydrochloric acid, at a temperature in the range of from 16 DEG C to 25 DEG C, so that the maximum viscosity of the dissolved chitosan solution is reached within 5 minutes after the acid contacts the chitosan. It is desirable to utilize chitosan having a high tap density and/or high bulk density in the kits of the present invention. In another aspect, the present invention provides methods for reducing absorption of lipids by the gastrointestinal tract of a mammalian body. The methods include the step of providing a consumer with a kit including chitosan, packaging, and instructions indicating that the chitosan may be consumed with food. The kits of the present invention are useful in the practice of the methods of the present invention. By utilizing the kits and/or methods for lipid absorption reduction of the present invention a consumer does not have to remember to consume lipid-absorbing chitosan in advance of food consumption.
摘要翻译：一方面，本发明提供了用于减少哺乳动物体的胃肠道吸收脂质的试剂盒。试剂盒包括壳聚糖，包装和说明，表明壳聚糖可能与食物一起食用。用于掺入本发明试剂盒中的壳聚糖在胃液中足够快地溶解，其不必在饭前提前消费，以便在胃中溶解，然后有效地将脂质捕获到消费者的胃肠道中。在本发明的试剂盒的一个具体实施方案中，壳聚糖具有在16℃至25℃的温度范围内溶解于100倍（w / w）过量的0.16N盐酸的性质。 C，使得在酸接触壳聚糖后5分钟内达到溶解的壳聚糖溶液的最大粘度。希望在本发明的试剂盒中使用具有高振实密度和/或高堆积密度的壳聚糖。另一方面，本发明提供了减少哺乳动物体的胃肠道吸收脂质的方法。所述方法包括向消费者提供包括壳聚糖，包装和说明壳聚糖可能被食物消耗的说明书的步骤。本发明的试剂盒可用于实施本发明的方法。通过利用本发明的用于减少脂质吸收的试剂盒和/或方法，消费者不必记住在食物消耗之前消耗脂质吸收壳聚糖。

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