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1. 发明申请

WO2012059745A1 FLUOROMETRY 审中-公开
标题翻译：荧光
公开(公告)号：WO2012059745A1
公开(公告)日：2012-05-10
申请号：PCT/GB2011/052114
申请日：2011-10-31
申请人： THOMPSON, Edward John , TAL, Ilan
发明人： THOMPSON, Edward John , TAL, Ilan
IPC分类号： G01N21/64
CPC分类号： G01N21/6408 , G01N21/645
摘要： The invention relates to fluorometry, and in particular to methods and apparatus for time- delayed detection of fluorescence in a sample, for example for use in a clinical setting. Exemplary embodiments disclosed relate to a fluorometer (100) comprising a light source (101), a light detector (102), a sample holder (103) disposed between the light source and light detector, a motor (104); and a light transmission modulator (105) disposed around the sample holder and comprising a pair of plates (106, 107) attached to the motor for rotation about a common axis (108), the pair of plates arranged to allow transmission from the source to the sample in a first rotated position, to allow transmission from the sample to the detector in a second rotated position and to block direct light transmission between the source and detector in both first and second rotated positions. Light signal data may be captured after stopping operation of the motor and while the light transmission modulator is rotating in order to reduce or eliminate electrical noise and mechanical vibrations from the motor.
摘要翻译：本发明涉及荧光测定法，特别涉及用于时间延迟检测样品中荧光的方法和装置，例如用于临床环境。所公开的示例性实施例涉及一种包括光源（101），光检测器（102），设置在光源和光检测器之间的样品保持器（103）的荧光计（100），马达（104）。以及光传输调制器（105），其设置在所述样品保持器周围并且包括附接到所述马达的一对板（106,107），用于围绕公共轴线（108）旋转，所述一对板被布置成允许从所述源传送到样品处于第一旋转位置，以允许在第二旋转位置从样品传输到检测器，并且阻止在第一和第二旋转位置中的源和检测器之间的直接光透射。光信号数据可以在电动机停止操作之后并且当光传输调制器旋转时被捕获，以减少或消除电动机的电噪声和机械振动。

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