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1. 发明申请

WO2012121485A3 METHOD FOR INDUCING IN VIVO MIGRATION OF STEM CELL 审中-公开
标题翻译：诱导干细胞移植的方法
公开(公告)号：WO2012121485A3
公开(公告)日：2012-12-13
申请号：PCT/KR2012000618
申请日：2012-01-26
申请人： TEGO SCIENCE INC , LEE JIN WOO , PARK MIN SUNG , KIM YUN HEE
发明人： LEE JIN WOO , PARK MIN SUNG , KIM YUN HEE
IPC分类号： A61L27/54 , A61K38/20 , A61L27/40 , C12N5/0775
CPC分类号： A61K38/20 , A61L27/54 , A61L27/58 , A61L2300/252 , A61L2300/412
摘要： The present invention relates to an implantable composition for treating a damaged tissue and a method for inducing an in vivo migration of a cell for treatment to a damaged tissue region. The present invention treats the damaged tissue by inducing/promoting homing of a cell for tissue generation by implanting a biodegradable scaffold reacted with chemotactic factors (for example, IL-8 or MIP-3a) to a damaged location (for example, joint cartilage or skin). Thus, the composition of the present invention can not only be applied to the treatment of a damaged bone tissue, a joint cartilage, or a skin tissue more conveniently and efficiently compared to the conventional technology, but can also be used as a useful treatment supplement agent in cell treatment using allogeneic cell by enabling efficient utilization of cell resources for treatment, the cell resources which are high in scarcity.
摘要翻译：本发明涉及用于治疗受损组织的可植入组合物和诱导细胞体内迁移以用于治疗至受损组织区域的方法。本发明通过将与趋化因子（例如IL-8或MIP-3a）反应的生物可降解支架植入受损部位（例如关节软骨或皮肤）。因此，与常规技术相比，本发明的组合物不仅可以更方便和更有效地用于治疗受损的骨组织，关节软骨或皮肤组织，而且还可以用作有用的治疗补充剂通过能够有效利用细胞资源进行治疗，使用同种异体细胞的细胞治疗剂，细胞资源稀缺性高。

2. 发明申请

WO2006014089A1 COSMETIC COMPOSITION CONTAINING KERATINOCYTE AND/OR FIBROBLAST 审中-公开
标题翻译：含有KERATINOCYTE和/或FIBROBLAST的化妆品组合物
公开(公告)号：WO2006014089A1
公开(公告)日：2006-02-09
申请号：PCT/KR2005/002555
申请日：2005-08-05
申请人： TEGO SCIENCE INC. , JEON, Sae-Wha , JANG, Dong-Il
发明人： JEON, Sae-Wha , JANG, Dong-Il
IPC分类号： A61K7/00
CPC分类号： A61K8/99 , A61K8/64 , A61K2800/84 , A61Q19/08
摘要： Disclosed herein is a cosmetic composition comprising lyophilized keratinocytes and/or fibroblasts and a method of preparing the cosmetic composition, comprising (1) culturing keratinocytes or fibroblasts; (2) lyophilizing the cultured keratinocytes or fibroblasts; and (3) incorporating the lyophilized keratinocytes and/or fibroblasts into a cosmetically acceptable carrier. When applied to the skin, the keratinocytes and/or fibroblasts contained in the cosmetic composition release already expressed cytokines to promote skin regeneration.
摘要翻译：本文公开了包含冻干角质形成细胞和/或成纤维细胞的化妆品组合物和制备化妆品组合物的方法，包括（1）培养角质形成细胞或成纤维细胞; （2）冻干培养的角化细胞或成纤维细胞; 和（3）将冻干的角质形成细胞和/或成纤维细胞掺入化妆品可接受的载体中。当施用于皮肤时，包含在化妆品组合物释放物中的角质形成细胞和/或成纤维细胞已经表达细胞因子以促进皮肤再生。

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