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1. 发明申请

WO2015116951A3 OPTICAL PROBE IMAGING METHOD AND SYSTEM 审中-公开
公开(公告)号：WO2015116951A3
公开(公告)日：2015-08-06
申请号：PCT/US2015/013816
申请日：2015-01-30
申请人： CANON U.S.A., INC. , THE GENERAL HOSPITAL CORPORATION , TEARNEY, Guillermo J. , KANG, Dongkyun , IKUTA, Mitsuhiro , YAMAZOE, Kenji , MACH, Anderson Thi , BRAUER, Jacob Schieffelin
发明人： TEARNEY, Guillermo J. , KANG, Dongkyun , IKUTA, Mitsuhiro , YAMAZOE, Kenji , MACH, Anderson Thi , BRAUER, Jacob Schieffelin
IPC分类号： A61B1/05 , A61B1/06 , A61B5/0215
摘要： Exemplary apparatus, systems, methods of making, and methods of using a configuration in an optical arrangement for forward viewing spectrally encoded endoscopy (SEE) probe can be provided. For example, the probe can comprise a light focusing component, a light guiding component, a light reflecting component, and a grating component.

2. 发明申请

WO2015116951A2 OPTICAL PROBE, LIGHT INTENSITY DETECTION, IMAGING METHOD AND SYSTEM 审中-公开
标题翻译：光学探测，光强度检测，成像方法与系统
公开(公告)号：WO2015116951A2
公开(公告)日：2015-08-06
申请号：PCT/US2015013816
申请日：2015-01-30
申请人： CANON USA INC , GEN HOSPITAL CORP , TEARNEY GUILLERMO J , KANG DONGKYUN , IKUTA MITSUHIRO , YAMAZOE KENJI , MACH ANDERSON THI , BRAUER JACOB SCHIEFFELIN
发明人： TEARNEY GUILLERMO J , KANG DONGKYUN , IKUTA MITSUHIRO , YAMAZOE KENJI , MACH ANDERSON THI , BRAUER JACOB SCHIEFFELIN
IPC分类号： A61B1/04
CPC分类号： G02B23/2453 , A61B1/00009 , A61B1/00096 , A61B1/00172 , A61B1/04 , A61B1/0661 , A61B1/07 , G02B3/0087 , G02B23/02 , G02B23/243 , G02B23/2469 , G02B23/26 , G02B27/1086 , G02B27/425 , H04N5/2256 , H04N9/07 , H04N2005/2255
摘要： Exemplary apparatus, systems, methods of making, and methods of using a configuration in an optical arrangement for forward viewing spectrally encoded endoscopy (SEE) probe can be provided. For example, the probe can comprise a light focusing component, a light guiding component, a light reflecting component, and a grating component.
摘要翻译：可以提供示例性的装置，系统，制造方法以及在光学装置中使用配置的方法，以用于正视观察频谱编码的内窥镜检查（SEE）探针。例如，探针可以包括光聚焦部件，导光部件，光反射部件和光栅部件。

3. 发明申请

WO2011109818A2 SYSTEM, METHODS AND COMPUTER- ACCESSIBLE MEDIUM WHICH PROVIDE MICOSCOPIC IMAGES OF AT LEAST ONE ANATOMICAL STRUCTURE AT A PARTICULAR RESOLUTION 审中-公开
标题翻译：系统，方法和计算机可访问的介质，其在特定分辨率下提供至少一个解剖结构的微观图像
公开(公告)号：WO2011109818A2
公开(公告)日：2011-09-09
申请号：PCT/US2011/027421
申请日：2011-03-07
申请人： THE GENERAL HOSPITAL CORPORATION , TEARNEY, Guillermo, J. , BOUMA, Brett, E. , GARDECKI, Joseph, A. , LIU, Linbo , MCLEOD, Robert, R.
发明人： TEARNEY, Guillermo, J. , BOUMA, Brett, E. , GARDECKI, Joseph, A. , LIU, Linbo , MCLEOD, Robert, R.
CPC分类号： A61B5/0066 , A61B5/0044 , A61B5/0075 , A61B5/0084 , G01B9/02091 , G02B6/32
摘要： Exemplary embodiments of apparatus, systems and methods can be provided for providing at least one electro-magnetic radiation to at least one sample. For example, a plurality of wave-guiding arrangements can be provided which are configured to (i) provide the electro-magnetic radiation(s), and (ii) at a point of emission of each of the wave guiding arrangements, cause a phase of each of the electro-magnetic radiation(s) to have a predetermined value. The exemplary apparatus can be part of a probe. Further the exemplary apparatus can include an interferometric arrangement provided in communication with the probe and/or be part of the probe.
摘要翻译：可以提供装置，系统和方法的示例性实施例，以向至少一个样品提供至少一个电磁辐射。例如，可以提供多个波导装置，其被配置为（i）提供电磁辐射，和（ii）在每个波导装置的发射点处，引起相位每个电磁辐射具有预定值。示例性装置可以是探针的一部分。此外，示例性装置可以包括与探针连接和/或成为探针的一部分提供的干涉装置。

4. 发明申请

WO2011008822A2 APPARATUS, SYSTEMS AND METHODS FOR MEASURING FLOW AND PRESSURE WITHIN A VESSEL 审中-公开
标题翻译：用于测量船内流量和压力的装置，系统和方法
公开(公告)号：WO2011008822A2
公开(公告)日：2011-01-20
申请号：PCT/US2010041923
申请日：2010-07-14
申请人： GEN HOSPITAL CORP , TEARNEY GUILLERMO J , SUTER MELISSA , BOUMA BRETT E , JAFFER FAROUC A
发明人： TEARNEY GUILLERMO J , SUTER MELISSA , BOUMA BRETT E , JAFFER FAROUC A
IPC分类号： A61B5/021 , A61B5/02 , A61B5/027
CPC分类号： A61B5/0261 , A61B5/0066 , A61B5/02007 , A61B5/0215 , A61B5/024
摘要： Exemplary embodiments of apparatus, system and method can be provided to measure a flow of fluid within an anatomical structure. For example, it is possible to use at least one first probe arrangement structured to be insertable into a vessel and configured to direct at least one radiation to at least one portion of the anatomical structure. Further, it is possible to provide at least one second arrangement which configured to detect an interference between a first radiation provided from the fluid via the probe arrangement and second a second radiation provided from a reference path as a function of wavelength thereof. Further, at least one third arrangement can be provided which is configured to determine at least one characteristic of the fluid as a function of the interference.
摘要翻译：可以提供设备，系统和方法的示例性实施例以测量解剖结构内的流体流量。例如，可以使用至少一个第一探针装置，所述第一探针装置被构造成可插入脉管并被配置为将至少一个辐射引导至解剖结构的至少一部分。此外，可以提供至少一个第二布置，其被配置为检测从流体经由探针布置提供的第一辐射与从参考路径提供的第二辐射之间的干涉作为其波长的函数。此外，可以提供至少一个第三布置，其被配置为根据干涉来确定流体的至少一个特性。

5. 发明申请

WO2010105197A3 NON-CONTACT OPTICAL SYSTEM, COMPUTER-ACCESSIBLE MEDIUM AND METHOD FOR MEASURING AT LEAST ONE MECHANICAL PROPERTY OF TISSUE USING COHERENT SPECKLE TECHNIQUES(S) 审中-公开
标题翻译：非接触式光学系统，计算机可访问介质和使用相关系数技术测量组织的至少一个机械性质的方法（S）
公开(公告)号：WO2010105197A3
公开(公告)日：2011-01-13
申请号：PCT/US2010027193
申请日：2010-03-12
申请人： GEN HOSPITAL CORP , NADKARNI SEEMANTINI K , TEARNEY GUILLERMO J
发明人： NADKARNI SEEMANTINI K , TEARNEY GUILLERMO J
IPC分类号： G01N33/483 , A61B6/00 , G01N21/00
CPC分类号： A61B5/0059 , A61B5/0062 , A61B5/02007
摘要： Exemplary embodiments of apparatus and method for determining at least one material property of an anatomical structure can be provided. According to one exemplary embodiment, it is possible to apply at least one first coherent radiation to at least one portion of the anatomical structure, and receive at least one second coherent radiation from such portion(s). The first and second coherent radiations can be associated with one another. In addition, it is possible to determine the material property based on the second coherent radiation(s). Such determination can be performed without (i) any portion of an apparatus performing the procedure causing an induction of at least one mechanical deformation on or in the anatomical structure, and/or (ii) any mechanical deformation on or in the anatomical structure.
摘要翻译：可以提供用于确定解剖结构的至少一种材料性质的装置和方法的示例性实施例。根据一个示例性实施例，可以将至少一个第一相干辐射施加到解剖结构的至少一部分，并且从这些部分接收至少一个第二相干辐射。第一和第二相干辐射可以彼此相关联。此外，可以基于第二相干辐射来确定材料特性。可以执行这种确定，而不需要（i）执行该过程的装置的任何部分，导致解剖结构上或解剖结构中的至少一个机械变形，和/或（ii）解剖结构上或解剖结构中的任何机械变形。

6. 发明申请

WO2010090837A3 ENDOSCOPIC BIOPSY APPARATUS, SYSTEM AND METHOD 审中-公开
标题翻译：内窥镜活体装置，系统和方法
公开(公告)号：WO2010090837A3
公开(公告)日：2010-11-18
申请号：PCT/US2010021514
申请日：2010-01-20
申请人： GEN HOSPITAL CORP , TEARNEY GUILLERMO J , BOUMA BRETT E , KANG DONGKYUN , SUTER MELISSA J
发明人： TEARNEY GUILLERMO J , BOUMA BRETT E , KANG DONGKYUN , SUTER MELISSA J
IPC分类号： A61B1/04
CPC分类号： A61B5/0066 , A61B5/0068 , A61B5/0075 , A61B5/0086
摘要： Exemplary embodiments of apparatus, method and system for determining a position on or in a biological tissue can be provided. For example, using such exemplary embodiment, it is possible to control the focus of an optical imaging probe. In another exemplary embodiment, it is possible to implement a marking apparatus together with or into an optical imaging probe. According to one exemplary embodiment, it is possible (using one or more arrangements) to receive information associated with at least one image of at least one portion of the biological tissue obtained using an optical imaging technique. Further, it is possible to, based on the information, cause a visible change on or in at least location of the portion(s) using at least one electro-magnetic radiation.
摘要翻译：可以提供用于确定生物组织上或生物组织中的位置的设备，方法和系统的示例性实施例。例如，使用这样的示例性实施例，可以控制光学成像探头的焦点。在另一个示例性实施例中，可以将标记设备与光学成像探针一起或者引入光学成像探针中。根据一个示例性实施例，可以（使用一个或多个布置）接收与使用光学成像技术获得的生物组织的至少一部分的至少一个图像相关联的信息。此外，基于所述信息，可以使用至少一个电磁辐射在所述部分的至少位置上或其中引起可见变化。

7. 发明申请

WO2010009144A3 APPARATUS CONFIGURED TO PROVIDE A WAVELENGTH-SWEPT ELECTRO-MANGNETIC RADIATION 审中-公开
标题翻译：配置为提供波浪式扫描电磁辐射的设备
公开(公告)号：WO2010009144A3
公开(公告)日：2010-05-14
申请号：PCT/US2009050563
申请日：2009-07-14
申请人： GEN HOSPITAL CORP , GOLDBERG BRIAN , TEARNEY GUILLERMO J , BOUMA BRETT EUGENE , MOTGAHIAN-NEZAM REZA
发明人： GOLDBERG BRIAN , TEARNEY GUILLERMO J , BOUMA BRETT EUGENE , MOTGAHIAN-NEZAM REZA
IPC分类号： H01S3/10
CPC分类号： H01S5/141 , G01J3/10 , H01S3/105 , H01S5/02248 , H01S5/101 , H01S5/143
摘要： Exemplary embodiments of apparatus according to the present disclosure are provided. For example, an apparatus for providing electromagnetic radiation to a structure can be provided. In one exemplary embodiment, the apparatus can provide at least one electromagnetic radiation, and include at least one first arrangement which can be configured to generate the electromagnetic radiation(s) having at least one wavelength that varies over time. The exemplary apparatus can also include at least one second arrangement which can be configured to power the first arrangement(s) independently from an external power source. In another exemplary embodiment the apparatus can include at least one particular arrangement which is configured to generate the electromagnetic radiation(s) having at least one wavelength that varies over time. The particular arrangement(s) can include a resonant cavity that has a roundtrip optical transit time of approximately less than 0.7 nsec.
摘要翻译：提供了根据本公开的设备的示例性实施例。例如，可以提供用于向结构提供电磁辐射的装置。在一个示例性实施例中，该设备可以提供至少一个电磁辐射，并且包括至少一个第一布置，该第一布置可以被配置为生成具有随时间变化的至少一个波长的电磁辐射。示例性设备还可以包括至少一个第二布置，其可以被配置为独立于外部电源向第一布置供电。在另一个示例性实施例中，该设备可以包括至少一个特定布置，其被配置为生成具有随时间变化的至少一个波长的电磁辐射。特定布置可以包括具有大约小于0.7纳秒的往返光学传播时间的谐振腔。

8. 发明申请

WO2010009136A3 APPARATUS AND METHODS FOR COLOR ENDOSCOPY 审中-公开
标题翻译：颜色内窥镜的装置和方法
公开(公告)号：WO2010009136A3
公开(公告)日：2010-04-08
申请号：PCT/US2009050553
申请日：2009-07-14
申请人： GEN HOSPITAL CORP , TEARNEY GUILLERMO J , BOUMA BRETT EUGENE , YELIN DVIR , KANG DONGKYUN
发明人： TEARNEY GUILLERMO J , BOUMA BRETT EUGENE , YELIN DVIR , KANG DONGKYUN
IPC分类号： A61B5/05 , A61B5/07 , G05F1/00
CPC分类号： A61B1/00172 , A61B1/04 , A61B5/0062 , A61B5/0066 , A61B5/0075 , A61B5/0084 , G01J3/0218 , G01J3/0256 , G01J3/18 , G01N21/4795 , G02B23/2423 , G02B23/2469
摘要： Exemplary embodiments of apparatus and method according to the present disclosure are provided. For example, an apparatus for providing electromagnetic radiation to a structure can be provided. The exemplary apparatus can include a first arrangement having at least two wave-guides which can be configured to provide there through at least two respective electro-magnetic radiations with at least partially different wavelengths from one another. The exemplary apparatus can also include a dispersive second arrangement structured to receive the electro-magnetic radiations and forward at least two dispersed radiations associated with the respective electro-magnetic radiations to at least one section of the structure. The wave-guide(s) can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate at least partially overlap of the dispersed radiations on the structure. In addition, another arrangement can be provided which can include at least two further wave-guides which can be configured to receive the electro-magnetic radiations from the dispersive arrangement. Each of the further wave-guides can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate a receipt of a different one of the such electro-magnetic radiations as a function of wavelengths thereof.
摘要翻译：提供了根据本公开的设备和方法的示例性实施例。例如，可以提供用于向结构提供电磁辐射的装置。示例性装置可以包括具有至少两个波导的第一装置，所述至少两个波导可以被配置成通过至少两个彼此具有至少部分不同波长的相应的电磁辐射来提供它们。示例性装置还可以包括分散第二装置，其被构造为接收电磁辐射，并将与各个电磁辐射相关联的至少两个分散的辐射转发到该结构的至少一个部分。波导可以相对于分散布置被构造和/或空间布置，以促进结构上分散的辐射的至少部分重叠。此外，可以提供另外的布置，其可以包括至少两个另外的波导，其可被配置为从分散布置接收电磁辐射。每个其它波导可以相对于色散装置构造和/或空间布置，以便于接收这样的电磁辐射中不同的一个作为其波长的函数。

9. 发明申请

WO2010009144A2 APPARATUS CONFIGURED TO PROVIDE A WAVELENGTH-SWEPT ELECTRO-MANGNETIC RADIATION 审中-公开
标题翻译：配置提供波长扫描电子辐射的装置
公开(公告)号：WO2010009144A2
公开(公告)日：2010-01-21
申请号：PCT/US2009/050563
申请日：2009-07-14
申请人： THE GENERAL HOSPITAL CORPORATION , GOLDBERG, Brian , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene , MOTGAHIAN-NEZAM, Reza
发明人： GOLDBERG, Brian , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene , MOTGAHIAN-NEZAM, Reza
IPC分类号： H01S3/10
CPC分类号： H01S5/141 , G01J3/10 , H01S3/105 , H01S5/02248 , H01S5/101 , H01S5/143
摘要： Exemplary embodiments of apparatus according to the present disclosure are provided. For example, an apparatus for providing electromagnetic radiation to a structure can be provided. In one exemplary embodiment, the apparatus can provide at least one electromagnetic radiation, and include at least one first arrangement which can be configured to generate the electromagnetic radiation(s) having at least one wavelength that varies over time. The exemplary apparatus can also include at least one second arrangement which can be configured to power the first arrangement(s) independently from an external power source. In another exemplary embodiment the apparatus can include at least one particular arrangement which is configured to generate the electromagnetic radiation(s) having at least one wavelength that varies over time. The particular arrangement(s) can include a resonant cavity that has a roundtrip optical transit time of approximately less than 0.7 nsec.
摘要翻译：提供了根据本公开的设备的示例性实施例。例如，可以提供用于向结构提供电磁辐射的装置。在一个示例性实施例中，该装置可以提供至少一个电磁辐射，并且包括至少一个第一布置，其可被配置为产生具有随时间变化的至少一个波长的电磁辐射。示例性装置还可以包括至少一个第二装置，其可被配置为独立于外部电源为第一装置供电。在另一个示例性实施例中，装置可以包括至少一个特定布置，其被配置为产生具有随时间变化的至少一个波长的电磁辐射。具体布置可以包括谐振腔，其具有大约小于0.7纳秒的往返光通过时间。

10. 发明申请

WO2010009136A2 APPARATUS AND METHODS FOR COLOR ENDOSCOPY 审中-公开
标题翻译：用于彩色内窥镜的装置和方法
公开(公告)号：WO2010009136A2
公开(公告)日：2010-01-21
申请号：PCT/US2009/050553
申请日：2009-07-14
申请人： THE GENERAL HOSPITAL CORPORATION , TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene , YELIN, Dvir , KANG, Dongkyun
发明人： TEARNEY, Guillermo, J. , BOUMA, Brett, Eugene , YELIN, Dvir , KANG, Dongkyun
IPC分类号： A61B5/05 , A61B5/07
CPC分类号： A61B1/00172 , A61B1/04 , A61B5/0062 , A61B5/0066 , A61B5/0075 , A61B5/0084 , G01J3/0218 , G01J3/0256 , G01J3/18 , G01N21/4795 , G02B23/2423 , G02B23/2469
摘要： Exemplary embodiments of apparatus and method according to the present disclosure are provided. For example, an apparatus for providing electromagnetic radiation to a structure can be provided. The exemplary apparatus can include a first arrangement having at least two wave-guides which can be configured to provide there through at least two respective electro-magnetic radiations with at least partially different wavelengths from one another. The exemplary apparatus can also include a dispersive second arrangement structured to receive the electro-magnetic radiations and forward at least two dispersed radiations associated with the respective electro-magnetic radiations to at least one section of the structure. The wave-guide(s) can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate at least partially overlap of the dispersed radiations on the structure. In addition, another arrangement can be provided which can include at least two further wave-guides which can be configured to receive the electro-magnetic radiations from the dispersive arrangement. Each of the further wave-guides can be structured and/or spatially arranged with respect to the dispersive arrangement to facilitate a receipt of a different one of the such electro-magnetic radiations as a function of wavelengths thereof.
摘要翻译：提供了根据本公开的装置和方法的示例性实施例。例如，可以提供用于向结构提供电磁辐射的装置。该示例性设备可以包括具有至少两个波导管的第一装置，该波导管可以被配置为通过至少两个彼此具有至少部分不同的波长的相应电磁辐射提供通过。示例性设备还可以包括色散第二布置，其被构造为接收电磁辐射并且将与相应电磁辐射相关联的至少两个散射辐射向前传递到结构的至少一个部分。（一个或多个）波导可以相对于弥散布置被结构化和/或空间布置，以促进分散辐射至少部分地在结构上重叠。另外，可以提供另一种布置，其可以包括至少两个另外的波导，其可以被配置为接收来自色散布置的电磁辐射。每个另外的波导可以相对于弥散布置被结构化和/或空间布置，以便于根据波长的函数接收不同的这种电磁辐射。

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