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    • 3. 发明申请
    • HOLLOW YARN MEMBRANE USED FOR BLOOD PURIFICATION AND BLOOD PURIFIER
    • 用于血液净化和血液净化器的中空丝膜
    • WO1997034687A1
    • 1997-09-25
    • PCT/JP1997000924
    • 1997-03-21
    • KANEKA CORPORATIONNAGAMATSU, HiroshiTAKATA, Satoshi
    • KANEKA CORPORATION
    • B01D71/68
    • D01F6/76B01D67/0016B01D69/08B01D71/68B01D2325/021B01D2325/022B01D2325/026B01D2325/20
    • A hollow yarn membrane made from a polysulfone resin for use in blood purification, which is entirely free from the risk of exudation of the membrane components, can be suitably used for hemodialysis and blood filtration, and can remove selectively and efficiently low-molecular proteins with molecular weights of 10,000 to 30,000 from the blood; and a blood purifier which can be suitably used as a hemodialyzer, hemodialyzer/filter, and blood filter. The membrane has slit micropores with an average width of 0.02 to 0.15 mu m on the internal surface thereof and micropores with an average diameter of 0.1 to 1 mu m on the external surface thereof, does not have macrovoids with diameters exceeding 10 mu m in any of the internal and external surfaces and the interior thereof, and has a water permeation rate of 400 to 2,500 ml/m .hr.mmHg and a total protein permeability of 1 % or below. The purifier comprises the above membrane put in a tubular housing provided with blood inlet and outlet, and either dialyzate inlet and outlet or filtrate outlet.
    • 由用于血液净化的聚砜树脂制成的中空丝膜完全没有膜组分渗出的风险,可以适用于血液透析和血液过滤,并且可以选择性和有效地去除低分子蛋白质 血液分子量为10,000〜30,000; 以及可以适当地用作血液透析器,血液透析器/过滤器和血液过滤器的血液净化器。 该膜在其内表面上具有平均宽度为0.02至0.15μm的狭缝微孔,并且在其外表面上具有平均直径为0.1至1μm的微孔在任何情况下都不具有直径超过10μm的大孔 的内表面和内表面,并且具有400至2500ml / m 2·hr·mmHg的水渗透速率和1%或更低的总蛋白渗透性。 净化器包括放置在具有血液入口和出口的管状壳体中的上述膜,以及透析液入口和出口或滤液出口。