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1. 发明申请

WO2008012310A1 CASPOFUNGIN FORMULATIONS 审中-公开
标题翻译： CASPOFUNGIN配方
公开(公告)号：WO2008012310A1
公开(公告)日：2008-01-31
申请号：PCT/EP2007/057623
申请日：2007-07-24
申请人： SANDOZ AG , WELZ, Christian , STUBAUER, Gottfried , SCHMARDA, Andreas , JENNEWEIN, Herwig , MACHER, Ingolf , LUDESCHER, Johannes
发明人： WELZ, Christian , STUBAUER, Gottfried , SCHMARDA, Andreas , JENNEWEIN, Herwig , MACHER, Ingolf , LUDESCHER, Johannes
IPC分类号： A61K38/12 , A61P31/10 , A61K9/19
CPC分类号： A61K9/19 , A61K9/0019 , A61K38/12 , A61K47/02 , A61K47/10 , A61K47/18 , A61K47/26
摘要： The present invention relates to pharmaceutical compositions comprising a pharmaceutically acceptable salt of caspofungin as active ingredient being useful for the prevention and/or treatment of fungal infections. Said compositions additionally comprise specific bulking agents and small amounts or no amounts of an additional pH modifier and may be in a liquid or solid form, e.g. may be lyophilized compositions. Said compositions show good stability and reduced amounts of sub-visible particulate matter formed in solutions which are reconstituted from the lyophilized product.
摘要翻译：本发明涉及包含卡泊芬净的药学上可接受的盐作为活性成分的药物组合物，其可用于预防和/或治疗真菌感染。所述组合物另外包含特定的填充剂和少量或不含量的另外的pH调节剂，并且可以是液体或固体形式，例如。可以是冻干组合物。所述组合物显示良好的稳定性和减少在从冻干产物重构的溶液中形成的亚可见颗粒物质的量。

2. 发明申请

WO1998023939A1 DEVICE FOR TAKING SAMPLES 审中-公开
标题翻译：样品摇篮
公开(公告)号：WO1998023939A1
公开(公告)日：1998-06-04
申请号：PCT/AT1997000257
申请日：1997-11-26
申请人： VÖLP, Markus , SEPPI, Thomas , STUBAUER, Gottfried
发明人： VÖLP, Markus
IPC分类号： G01N01/38
CPC分类号： G01N35/1097 , G01N1/38 , G01N30/06 , G01N33/1806 , G01N35/085 , G01N2030/027
摘要： Device for conveying samples, for a unit for determining the oxygen concentration of a sample, whereby the unit has an oxygen detector device, preferably an HPLC-installation combined with an electrochemical detector, for determining the oxygen concentration, and with which the sample conveyor can be connected. The sample conveyor has at least one sample chamber (1), which can be sealed so as to be gastight, for accommodating the oxygen-containing sample. A compensation device (15, 20) is also envisaged, connected to the sample chamber (1), for introducing a fluid with defined oxygen concentration into the sample chamber (1), as is a transfer device (17), connected with the sample chamber (1), for transferring a predetermined amount of liquid from the sample chamber (1) to the oxygen detector device.
摘要翻译：为用于测定样品中的氧浓度，一装置进样装置，其中用于确定的氧气检测器的氧浓度的装置的装置，优选为HPLC系统的电化学检测器，利用该样本施加装置可被带入连接组合。示例应用程序设备具有用于接收该含氧样品中至少一种气密的可封闭的样品室（1）。此外，它是一个与样品室（1）相关的补偿装置（15，20），用于将具有在所述样品室中的限定的氧浓度的流体（1），并与所述样品室（1）与输送装置（17）用于传送一个预定提供从所述样品室（1）与氧气检测器装置流体的量。

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