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1. 发明申请

WO2011065937A1 VEHICLE WITH PARTICULATE RESISTANT WINDSHIELD 审中-公开
标题翻译：具有耐磨性的车辆
公开(公告)号：WO2011065937A1
公开(公告)日：2011-06-03
申请号：PCT/US2009/065719
申请日：2009-11-24
申请人： INTERNATIONAL TRUCK INTELLECTUAL PROPERTY COMPANY, LLC , STRAND, David
发明人： STRAND, David
IPC分类号： B08B6/00 , B60S1/02
CPC分类号： B60J1/00 , B60S1/02
摘要： A vehicle (10) having a particulate resistant windshield (12) comprises a windshield, an ionizer (16), and a controller (20). The windshield is disposed in a cab portion (14) of a vehicle. The windshield has a periphery. The ionizer has at least one electrode (18) disposed adjacent the periphery of the windshield. The controller is in electrical communication with the ionizer. The controller generates a signal transmitted to the ionizer to control generation of ions by the ionizer. The ions generated by the ionizer are directed towards at least a portion of the windshield.
摘要翻译：具有防尘挡风玻璃（12）的车辆（10）包括挡风玻璃，电离器（16）和控制器（20）。挡风玻璃设置在车辆的驾驶室部分（14）中。挡风玻璃有外围。电离器具有邻近挡风玻璃周边设置的至少一个电极（18）。控制器与电离器电气通信。控制器产生传输到离子发生器的信号，以控制由离子发生器产生的离子。由离子发生器产生的离子指向挡风玻璃的至少一部分。

2. 发明申请

WO2004104457A2 BULK FLUID FLOW GATE 审中-公开
标题翻译：大流量流动门
公开(公告)号：WO2004104457A2
公开(公告)日：2004-12-02
申请号：PCT/US2004015934
申请日：2004-05-19
申请人： PROTASIS CORP , STRAND DAVID , LEATZOW DAN M
发明人： STRAND DAVID , LEATZOW DAN M
IPC分类号： G01N27/447 , F16K
CPC分类号： B01L3/502746 , B01L2300/0645 , B01L2300/0877 , B01L2300/0887 , B01L2300/1894 , B01L2400/0421 , B01L2400/082 , G01N27/44756 , Y10T137/2191
摘要： A bulk fluid flow gate is provided. In accordance with certain exemplary embodiments the bulk fluid flow gate includes a first and second entry port and first and second exit ports. Bulk fluid is flowed into the chamber to provide greater hydrodynamic resistance at the first exit port than at the second exit port. The bulk fluid flow gate is useful for separation, testing and or analysis of analytes. Methods of making and using the bulk fluid flow gate are also provided. In accordance with certain exemplary embodiments a fluid flow gate includes a first entry port into a microscale chamber and first and second exit ports. In accordance with certain embodiments a fluid flow gate includes a first entry port to a chamber and first and second exit ports, wherein greater hydrodynamic resistance is provided at the first exit port than at the second exit port.
摘要翻译：提供散装流体流动门。根据某些示例性实施例，本体流体流动门包括第一入口端口和第二入口端口以及第一和第二出口端口。散装流体流入室，以在第一出口处提供比在第二出口处更大的流体动力阻力。散装流体闸门可用于分析，分析和分析。还提供了制造和使用散装流体闸门的方法。根据某些示例性实施例，流体流动门包括进入微型室和第一和第二出口的第一入口。根据某些实施例，流体流动门包括到腔室的第一进入口和第一和第二出口，其中在第一出口处提供比在第二出口处更大的流体动力阻力。

3. 发明申请

WO2004065937A2 METHOD AND APPARATUS DETERMINING THE ISOELECTRIC POINT OF CHARGED ANALYTE 审中-公开
标题翻译：方法和装置确定充电分析仪的电压点
公开(公告)号：WO2004065937A2
公开(公告)日：2004-08-05
申请号：PCT/US2004/000630
申请日：2004-01-12
申请人： PROTASIS CORPORATION , STRAND, David , LEATZOW, Dan, M.
发明人： STRAND, David , LEATZOW, Dan, M.
IPC分类号： G01N
CPC分类号： B01D61/425 , C07K1/28 , G01N27/44704
摘要： Devices are provided for determining the isoelectric point of a charged analyte, comprising a titration chamber and an electrode chamber. The electrode chamber comprises at least two electrodes, for example, an electrode array. Either or both of the titration chamber and the electrode chamber may have a shaped geometry. The electrodes are operative, in conjunction with the shaped geometry of the chamber(s) where appropriate, to generate an electric field gradient in the titration chamber. Permeable material separates the titration chamber and the electrode chamber. A pH Sensor is located in the titration chamber for obtaining the pH of the first fluid. Certain preferred embodiments further include an analyte band detector for detecting the presence and optionally the location of a focused band of charged solute. Methods are provided for determining the isoelectric point of a charged analyte comprising introducing a carrier fluid comprising a Charge analyte into the titration chamber of a device as just described and applying an electric field gradient to focus the charged analyte into a focused band. The pH of the carrier fluid is incremented or adjusted to shift the location of the focused band of charged analyte, and the pH and location of the focused band of charged analyte are obtained for a plurality of locations and pH's and the isoelectric point is determined from such data.
摘要翻译：提供了用于确定带电分析物的等电点的装置，包括滴定室和电极室。电极室包括至少两个电极，例如电极阵列。滴定室和电极室中的任一个或两者可以具有成形几何形状。电极在适当的情况下与室的成形几何结合起作用，以在滴定室中产生电场梯度。渗透材料分离滴定室和电极室。 pH传感器位于滴定室中以获得第一流体的pH。某些优选实施例还包括用于检测带电溶质的聚焦带的存在和可选地位置的分析物带检测器。提供了用于确定带电分析物的等电点的方法，包括将包含电荷分析物的载体流体引入如上所述的装置的滴定室中，并施加电场梯度以将带电分析物聚焦到聚焦带中。载体流体的pH被递增或调整以移动带电分析物的聚焦带的位置，并且对于多个位置和pH值获得带电分析物的聚焦带的pH和位置，并且等电点由这样的数据。

4. 发明申请

WO2004051247A2 ELECTROPHORETIC DEVICES, INSTRUMENTS AND SYSTEMS INCLUDING SAME 审中-公开
标题翻译：电泳装置，仪器和系统，包括它们
公开(公告)号：WO2004051247A2
公开(公告)日：2004-06-17
申请号：PCT/US0338170
申请日：2003-12-01
申请人： PROTASIS CORP , STRAND DAVID , LEATZOW DAN M
发明人： STRAND DAVID , LEATZOW DAN M
IPC分类号： G01N27/447 , G01N27/00
CPC分类号： G01N27/44795 , B01D57/02
摘要： Devices, systems and methods are provided for processing fluid samples containing one or more analytes. In certain examples, an electrophoretic device comprises a separation chamber and an electrode chamber, each of which may be uniform or non-uniform. The electrode chamber includes two or more electrodes or may include an electrode array. Molecular sieve may be included in the separation chamber, and the molecular sieve is operative to shift the location at which a stationary focused band of a charged analyte forms under a given set of focusing process parameters. Such systems are especially suitable for linking up analytical instruments in a hyphenated fashion, particularly where the instruments have differing system parameters.
摘要翻译：提供设备，系统和方法来处理含有一种或多种分析物的流体样品。在某些实例中，电泳装置包括分离室和电极室，每个电极室可均匀或不均匀。电极室包括两个或更多个电极或者可以包括电极阵列。分子筛可以包括在分离室中，并且分子筛可操作以在给定的一组聚焦过程参数下移动带电分析物的固定聚焦带的位置。这种系统特别适用于以连字的方式连接分析仪器，特别是在仪器具有不同系统参数的情况下。

5. 发明申请

WO2003102737A3 METHOD AND DEVICE FOR ULTRASONICALLY MANIPULATING PARTICLES WITHIN A FLUID 审中-公开
公开(公告)号：WO2003102737A3
公开(公告)日：2003-12-11
申请号：PCT/US2003/017274
申请日：2003-06-03
申请人： PROTASIS CORPORATION , STRAND, David , BARROW, David , CEFAI, Joseph
发明人： STRAND, David , BARROW, David , CEFAI, Joseph
IPC分类号： B01D43/00
摘要： Fluid-handling methods and devices for ultrasonic manipulation of fluid-borne particles comprise a fluid-handling manifold and an ultrasonic particle manipulator defining an ultrasonic cavity within the manifold. Fluid-borne particles introduced into the manifold are manipulated by controlling ultrasonic standing waves at the ultrasonic cavity. Cavities having non-uniform configurations, asymmetric standing waves and/or multiple ultrasonic cavities within the manifold are operative to control the movement of the fluid-borne particles, optionally including collecting and holding such particles, transferring particles through an intersection from one channel to another, etc. Solid phase extraction (SPE) particles, biological particles and other fluid-borne particles can be manipulated within the fluid-handling manifold.

6. 发明申请

WO1997034734A1 DETERMINANT WING ASSEMBLY 审中-公开
标题翻译：决定会议大会
公开(公告)号：WO1997034734A1
公开(公告)日：1997-09-25
申请号：PCT/US1997004550
申请日：1997-03-21
申请人： THE BOEING COMPANY , MUNK, Clayton, L. , NELSON, Paul, E. , STRAND, David, E.
发明人： THE BOEING COMPANY
IPC分类号： B23P11/02
CPC分类号： G05B19/44 , B23P21/00 , B23P2700/01 , B25B5/122 , B25B5/163 , B25B11/005 , B25B11/007 , B64C3/18 , B64C3/26 , B64F5/10 , G05B19/401 , G05B19/4083 , G05B2219/36503 , G05B2219/49136 , Y02P90/265 , Y10T29/49764 , Y10T29/49885 , Y10T29/49895 , Y10T29/49904
摘要： A method and apparatus for manufacturing wings is disclosed. The apparatus includes a fixture (42) that holds wing panels (30, 32) for drilling and edge trimming by accurate numerically controlled machine tools (40). The method includes attaching spars (34, 36) to the wing panels (30, 32) using coordination holes to locate the spars (34, 36) accurately on the wing panels (30, 32) in accordance with an original engineering design, and also attaching in-spar ribs (38) to rib posts (204) on the spars (34, 36) using accurately drilled coordination holes in the ends of the ribs (214) and in the rib posts (204). The method further includes determining the wing contour by the configuration of the spars (34, 36) and ribs (38).
摘要翻译：用于制造机翼的方法和装置包括一个固定装置，其通过使用原始数字部分定义记录的精确的数控机床保持用于钻孔和边缘修剪的翼板，利用细节部件或子组件的关键特征之间的空间关系，由协调特征加工成部件和组件，从而使部件和组件固有地决定了机翼的尺寸和轮廓。翼片使用协调孔连接到翼板上，以根据原始工程设计将翼梁准确地定位在面板上，并且翼梁用肋板上的肋柱连接，使用准确钻孔的协调孔肋骨和肋骨柱。机翼轮廓由翼梁和肋骨的结构决定，而不是通过任何常规的硬工具来确定传统工艺中的机翼轮廓。

7. 发明申请

WO2005001518A3 METHOD OF MELT-FORMING OPTICAL DISK SUBSTRATES 审中-公开
标题翻译：熔融成形光盘基材的方法
公开(公告)号：WO2005001518A3
公开(公告)日：2006-04-20
申请号：PCT/US2004016664
申请日：2004-05-27
申请人： ENERGY CONVERSION DEVICES INC , HENNESSEY MICHAEL , GUTMAN GEORGE , STRAND DAVID , CLARK BARRY
发明人： HENNESSEY MICHAEL , GUTMAN GEORGE , STRAND DAVID , CLARK BARRY
IPC分类号： B29C35/08 , B29C43/02 , B29C59/02 , B29C59/04 , G02B20060101 , B05D5/00
CPC分类号： B29C59/022 , B29C43/00 , B29C43/021 , B29C59/026 , B29C59/04 , B29C2035/0811 , B29C2043/025 , B29C2059/023 , B29K2105/256 , B29L2017/00 , B29L2017/005
摘要： The present invention provides a method for the continuous manufacturing of optical memory or optical memory substrates, and/or optical disks, which includes supplying a web of polymeric material between two mating platens, melt-forn-xing at least one microform image, such as an information track structure for an optical device, into the web with a substantially flat stamper, heating a substantial portion of the melt formed cross section of the web of polymeric material to the melt flow temperature (T
摘要翻译：本发明提供了用于连续制造光学存储器或光学存储器基板和/或光盘的方法，其包括在两个配合压板之间提供聚合物材料的网状物，熔化至少一个微型图像，例如用于光学装置的信息轨道结构，用基本平坦的压模进入幅材，将聚合物材料幅材的熔体形成横截面的大部分加热到熔体流动温度（T

8. 发明申请

WO2004104555A3 FLUID LOGIC DEVICE 审中-公开
公开(公告)号：WO2004104555A3
公开(公告)日：2004-12-02
申请号：PCT/US2004/016267
申请日：2004-05-19
申请人： PROTASIS CORPORATION , STRAND, David , LEATZOW, Dan, M
发明人： STRAND, David , LEATZOW, Dan, M
IPC分类号： B01D15/08
摘要： Novel fluid logic devices are disclosed. Certain examples of the fluid logic devices include two or more fluid logic gates that are each operative to select and/or directy analytes in a sample into one or more fluid flow channels in communication with the fluid logic gates. The fluid logic device can be part of a larger system, such as a chromatogarphy system, or can be stand-alone device.

9. 发明申请

WO2004072611A2 VORTEX-STABILIZED ELECTROPHORETIC DEVICES AND METHODS 审中-公开
标题翻译：涡旋稳定的电泳装置和方法
公开(公告)号：WO2004072611A2
公开(公告)日：2004-08-26
申请号：PCT/US2004003490
申请日：2004-02-06
申请人： UNIV WASHINGTON STATE , IVORY CORNELIUS F , TRACY NOAH I , STRAND DAVID , LEATZOW DAN M
发明人： IVORY CORNELIUS F , TRACY NOAH I , STRAND DAVID , LEATZOW DAN M
IPC分类号： G01N20060101 , G01N27/26 , G01N27/447 , G01N
CPC分类号： G01N27/44795 , C07K1/26
摘要： A vortex-stabilized electrophoretic processor comprises an annular processing chamber at least partly defined by concentric first and second processing chamber surfaces. At least one of the processing chamber surfaces is rotatable relative to the other processing chamber surface. The electrophoretic processor further comprises an electric field generator operative to be energized to establish a dynamic field gradient within the processing chamber. At least one fluid port is provided, having fluid communication with the processing chamber. The electric field generator may comprise an elongate electrode array positioned within a central bore of a rotor forming the inside surface of the processing chamber. One or both of the processing chamber surfaces can have shaping comprising multiple spaced tines or annular ridges extending toward the other of the processing chamber surfaces.
摘要翻译：涡流稳定的电泳处理器包括至少部分由同心的第一和第二处理室表面限定的环形处理室。至少一个处理室表面可相对于另一个处理室表面旋转。电泳处理器还包括电场发生器，该电场发生器可操作以被激励以在处理室内建立动态场梯度。提供至少一个流体端口，其与处理腔室流体连通。电场发生器可以包括定位在形成处理室的内表面的转子的中心孔内的细长电极阵列。处理室表面中的一个或两个可以具有包括多个间隔开的尖端或环形脊的成形，所述多个间隔的尖端或环形脊朝着处理室表面中的另一个延伸。

10. 发明申请

WO2004065619A2 DEVICES AND METHODS FOR FOCUSING ANALYTES IN AN ELECTRIC FIELD GRADIENT II 审中-公开
标题翻译：用于在电场梯度中聚焦分析物的装置和方法II
公开(公告)号：WO2004065619A2
公开(公告)日：2004-08-05
申请号：PCT/US2004/000659
申请日：2004-01-12
申请人： PROTASIS CORPORATION , STRAND, David , LEATZOW, Dan, M.
发明人： STRAND, David , LEATZOW, Dan, M.
IPC分类号： C12Q
CPC分类号： G01N27/44795 , C07K1/26
摘要： Devices are provided for separating and focusing analytes, comprising a separation chamber and electrodes separated from the separation chamber by a membrane. The electrodes are operative to generate an electric field in the separation chamber. Molecular sieve in the separation chamber is operative to shift the location at which a stationary focused band of the analyte forms under a given set of focusing process parameters. Methods are provided for separating and focusing charged analytes, comprising introducing a first fluid comprising at least one charged analyte into the separation chamber of a device as just described, applying an electric field gradient to the separation chamber to focus the charged analyte at a location in the separation chamber. Methods are provided for separating and focusing un-charged (including inadequately charged) analytes, comprising introducing a fluid comprising at least the uncharged analyte and lipids, micelles and/or vesicles into the separation chamber of a device as just described, and applying an electric field gradient to the separation chamber to focus the analyte (in association with the lipids, micelles and/or vesicles) at a location in the separation chamber.
摘要翻译：提供了用于分离和聚焦分析物的装置，包括分离室和通过膜与分离室分离的电极。电极可操作以在分离室中产生电场。分离室中的分子筛可操作以在给定的一组聚焦过程参数下移动分析物的固定聚焦带形成的位置。提供了用于分离和聚焦带电分析物的方法，包括将如上所述将包含至少一种带电分析物的第一流体引入装置的分离室中，向分离室施加电场梯度以将带电分析物聚焦在位于分离室。提供了用于分离和聚焦未充电（包括未充足电）的分析物的方法，包括将至少包含不带电荷的分析物和脂质，胶束和/或囊泡的流体引入到刚刚描述的装置的分离室中，并施加电场分离室，以将分析物（与脂质，胶束和/或囊泡结合）聚焦在分离室中的位置。

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