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1. 发明申请

WO2019173853A3 MODULAR FLOTATION DEVICE WITH MECHANISM TO REMOVABLY ATTACH TO OTHER MODULAR DEVICES 审中-公开
公开(公告)号：WO2019173853A3
公开(公告)日：2019-09-12
申请号：PCT/US2019/030945
申请日：2019-05-06
申请人： ANDERSEN, Mike Kirk , BANNON, Theresa M. , CALLAHAN, Matthew James , CHANG, Justin Chyun , FINKLE, Joshua Lee , HOWELL, Nichole , KOMOROUS-KING, Vlasta Anastasia , LEE-SCHMIDT, Michelle Sau Kuen , LIU, Chenyu , MOORE, Steven James , ROMULUS, Carl , SKAATES, James Adam , STEWART, Andrew Richardson , WILKINS, David Jason
发明人： ANDERSEN, Mike Kirk , BANNON, Theresa M. , CALLAHAN, Matthew James , CHANG, Justin Chyun , FINKLE, Joshua Lee , HOWELL, Nichole , KOMOROUS-KING, Vlasta Anastasia , LEE-SCHMIDT, Michelle Sau Kuen , LIU, Chenyu , MOORE, Steven James , ROMULUS, Carl , SKAATES, James Adam , STEWART, Andrew Richardson , WILKINS, David Jason
IPC分类号： A47C15/00 , A63H23/10 , B63C9/30
摘要： One or more embodiments disclosed herein relate generally to flotation devices, and more specifically to modular flotation devices with a mechanism to removably attach to other modular devices. In one embodiments, an apparatus includes a first flotation module and a first connector coupled to the first flotation module. The first connector has a first end portion, a second end portion and a sidewall extended from the first end portion to the second end portion. The sidewall defines a plurality of circumferentially defined stepped portions configured to matingly engage a second connector of a second flotation module to couple the first flotation module to the second flotation module. The first connector is selectively operative as one of a female connector or a male connector with respect to the second connector.

2. 发明申请

WO2019173853A2 MODULAR FLOTATION DEVICE WITH MECHANISM TO REMOVABLY ATTACH TO OTHER MODULAR DEVICES 审中-公开
公开(公告)号：WO2019173853A2
公开(公告)日：2019-09-12
申请号：PCT/US2019/030945
申请日：2019-05-06
申请人： ANDERSEN, Mike Kirk , BANNON, Theresa M. , CALLAHAN, Matthew James , CHANG, Justin Chyun , FINKLE, Joshua Lee , HOWELL, Nichole , KOMOROUS-KING, Vlasta Anastasia , LEE-SCHMIDT, Michelle Sau Kuen , LIU, Chenyu , MOORE, Steven James , ROMULUS, Carl , SKAATES, James Adam , STEWART, Andrew Richardson , WILKINS, David Jason
发明人： ANDERSEN, Mike Kirk , BANNON, Theresa M. , CALLAHAN, Matthew James , CHANG, Justin Chyun , FINKLE, Joshua Lee , HOWELL, Nichole , KOMOROUS-KING, Vlasta Anastasia , LEE-SCHMIDT, Michelle Sau Kuen , LIU, Chenyu , MOORE, Steven James , ROMULUS, Carl , SKAATES, James Adam , STEWART, Andrew Richardson , WILKINS, David Jason
IPC分类号： B63B22/22
摘要： One or more embodiments disclosed herein relate generally to flotation devices, and more specifically to modular flotation devices with a mechanism to removably attach to other modular devices. In one embodiments, an apparatus includes a first flotation module and a first connector coupled to the first flotation module. The first connector has a first end portion, a second end portion and a sidewall extended from the first end portion to the second end portion. The sidewall defines a plurality of circumferentially defined stepped portions configured to matingly engage a second connector of a second flotation module to couple the first flotation module to the second flotation module. The first connector is selectively operative as one of a female connector or a male connector with respect to the second connector.

3. 发明申请

WO2018102616A1 FRACTURE TARGETED BONE REGENERATION THROUGH PARATHYROID HORMONE RECEPTOR STIMULATION 审中-公开
公开(公告)号：WO2018102616A1
公开(公告)日：2018-06-07
申请号：PCT/US2017/064081
申请日：2017-11-30
申请人： PURDUE RESEARCH FOUNDATION , LOW, Philip S. , LOW, Stewart Andrew , NIELSEN, Jeffrey
发明人： LOW, Philip S. , LOW, Stewart Andrew , NIELSEN, Jeffrey
IPC分类号： A61K31/00 , A61K31/445 , A61K31/4535
摘要： Disclosed herein includes a drug delivery system comprising at least one peptide and a targeting ligand for bone fracture and/or for bone healing. Some embodiments include a peptide delivery system comprising at least an acidic, basic, hydrophilic, hydrohobic or neutral peptide linked to an acidic peptide or nonpeptidic polyanion for use in targeting the aforementioned attached peptide to a bone fracture surface. In some embodiments, a conjugated peptide expresses an anabolic function that acts through PTH receptor 1, and various formats of targeting ligands guide the drug to raw hydroxyapatite. This system offsets some side effects caused by free anabolic drug, such as high blood calcium concentration

4. 发明申请

WO2010062927A3 SUBSTITUTED OCTAHYDROCYCLOPNTA (C) PYRROL-4 -AMINES AS CALCIUM CHANNEL BLOCKERS 审中-公开
标题翻译：取代的OCTAHYDROCYCLOPNTA（C）PYRROL-4-AMINES作为钙通道阻断剂
公开(公告)号：WO2010062927A3
公开(公告)日：2010-07-22
申请号：PCT/US2009065847
申请日：2009-11-25
申请人： ABBOTT LAB , STEWART ANDREW , SEARLE XENIA , DARCZAK DARIA , YEUNG MING , DIDOMENICO STANLEY
发明人： STEWART ANDREW , SEARLE XENIA , DARCZAK DARIA , YEUNG MING , DIDOMENICO STANLEY
IPC分类号： C07D209/02 , A61K31/403
CPC分类号： C07D209/02
摘要： The present application relates to calcium channel inhibitors containing compounds of formula (I), wherein L1, L2, R1, R2, and R3 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
摘要翻译：本申请涉及含有式（I）化合物的钙通道抑制剂，其中L1，L2，R1，R2和R3如说明书中所定义。本申请还涉及包含这些化合物的组合物，以及使用这些化合物和组合物治疗病症和障碍的方法。

5. 发明申请

WO2009126484A2 COMPUTER PROGRAM UPDATES FOR MOBILE COMPUTING DEVICE 审中-公开
标题翻译：移动计算设备的计算机程序更新
公开(公告)号：WO2009126484A2
公开(公告)日：2009-10-15
申请号：PCT/US2009/039093
申请日：2009-04-01
申请人： PALM, INC. , DATTA, Mainak , STEWART, Andrew , FAN, James (jianhua) , SHIRADWADE, Sateesh, K.
发明人： DATTA, Mainak , STEWART, Andrew , FAN, James (jianhua) , SHIRADWADE, Sateesh, K.
IPC分类号： H04W8/24 , G06F9/445 , H04W88/02
CPC分类号： H04L67/06 , G06F8/65 , H04L67/34 , H04M1/72525
摘要： A system and method for updating a computer program on a mobile computing device comprises uploading of packages to a repository, wherein each package comprises update data for a different portion of the computer program, a server identifying portions of the computer program to be updated on a device based on comparing information reported by the device and metadata about packages in the repository and a download server configured to wirelessly download the packages to the mobile computing device. The device may report back installation status to a server.
摘要翻译：用于更新移动计算装置上的计算机程序的系统和方法包括将包上载到储存库，其中每个包包括计算机程序的不同部分的更新数据，服务器标识基于比较由设备报告的信息和关于存储库中的包的元数据在设备上更新计算机程序，以及配置为将包无线地下载到移动计算设备的下载服务器。设备可能会将安装状态报告给服务器。

6. 发明申请

WO2008059266A3 MEDICAL DEVICE 审中-公开
标题翻译：医疗装置
公开(公告)号：WO2008059266A3
公开(公告)日：2009-07-23
申请号：PCT/GB2007004382
申请日：2007-11-16
申请人： MEDTRADE PRODUCTS LTD , HARDY CRAIG JULIAN , DARBY STEWART ANDREW , EASON ANDREW GUY
发明人： HARDY CRAIG JULIAN , DARBY STEWART ANDREW , EASON ANDREW GUY
IPC分类号： A61L15/44 , A61F13/15 , A61F15/00 , A61L15/62 , A61L26/00
CPC分类号： A61F13/15211 , A61F2013/00906 , A61L15/44 , A61L15/62 , A61L2300/418 , A61L2300/622
摘要： A medical device for delivery of a therapeutic agent to a physiological target site, said device comprising a flexible receptacle containing said therapeutic agent, wherein at least a part of the receptacle is formed of a water-soluble or water-dispersible material. The therapeutic agent may comprise a haemostatic agent and the physiological target site may comprise a wound.
摘要翻译：一种用于将治疗剂递送到生理目标部位的医疗装置，所述装置包括容纳所述治疗剂的柔性容器，其中容器的至少一部分由水溶性或水分散性材料形成。治疗剂可以包含止血剂，并且生理目标部位可以包括伤口。

7. 发明申请

WO2009082665A1 A FLOW CONTROL METHOD AND APPARATUS 审中-公开
标题翻译：流量控制方法和装置
公开(公告)号：WO2009082665A1
公开(公告)日：2009-07-02
申请号：PCT/US2008/087376
申请日：2008-12-18
申请人： FUEL TECH, INC. , BIBLE, Stewart, Andrew , TRIECE, Caleb, Douglas , TAN, Jason, David
发明人： BIBLE, Stewart, Andrew , TRIECE, Caleb, Douglas , TAN, Jason, David
IPC分类号： B05B1/26
CPC分类号： F15D1/04
摘要： The disclosure relates to air pollution control, and specifically to an apparatus for redirecting fluid flow in a plenum to improve flow performance and, therefore, improved air pollution control, especially in selective catalytic NO x reduction. The apparatus employs an array of flat blades mounted at an angle with respect to the inlet (upstream) fluid flow, such that the blades are titled with respect to that flow and correspondingly redirect the flow in a desired direction. The apparatus, which can also referred to as a 'GSG' or 'graduated straightening grid,' has a range of applications, and offers a number of performance, structural, and economic advantages in large-scale applications.
摘要翻译：本公开涉及空气污染控制，具体涉及用于重新定向气室中的流体流动的设备，以改善流动性能，并因此改善空气污染控制，特别是在选择性催化NOx还原中。该装置使用相对于入口（上游）流体流一角度安装的平面叶片阵列，使得叶片相对于该流动被标题，并且相应地沿着所需方向重新定向流动。该仪器也可称为“GSG”或“刻度矫直电网”，具有广泛的应用，并在大规模应用中提供了许多性能，结构和经济优势。

8. 发明申请

WO1994014762A1 OXIME ETHER DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY 审中-公开
标题翻译：具有LIPOXYGENASE抑制活性的OXIME醚衍生物
公开(公告)号：WO1994014762A1
公开(公告)日：1994-07-07
申请号：PCT/US1993012152
申请日：1993-12-14
申请人： ABBOTT LABORATORIES , BROOKS, Dee, W. , STEWART, Andrew, O. , MAKI, Robert, G.
发明人： ABBOTT LABORATORIES
IPC分类号： C07C259/06
CPC分类号： C07D207/335 , C07C275/64 , C07D307/58 , C07D333/22 , C07D333/58
摘要： The present invention provides certain substituted oxime ether compounds which inhibit lipoxygenase enzyme activity and are useful in the treatment of allergic and inflammatory disease states. The compounds of this invention have structure (I) where M is hydrogen, a pharmaceutically acceptable cation, or a pharmaceutically acceptable metabolically cleavable group; p and q are independently zero or one, with the proviso that (i) p and q may not both be the same; (ii) when p is one and q is zero, R is selected from the group consisting of hydrogen, straight or branched alkyl of from one to twelve carbon atoms, and cycloalkyl of from three to eight carbon atoms; and (iii) when p is zero and q is one, R is selected from the group consisting of hydrogen, alkyl of from one to twelve carbon atoms, cycloalkyl of from three to eight carbon atoms, and -NR1R2. L1 is a direct bond or is selected from the group consisting of alkyl of from one to six carbon atoms, alkylenyl, of from one to six carbon atoms, and alkynyl of from two to six carbon atoms; L2 is a direct bond or is alkyl of from one to six carbon atoms; Z is selected from the group consisting of hydrogen, alkyl of from one to six carbon atoms, and halosubstituted alkyl of from one to six carbon atoms; and A is optionally substituted carbocyclic or heterocyclic aryl, arylalkyl, or aryloxy.
摘要翻译：本发明提供某些抑制脂氧合酶活性的取代的肟醚化合物，可用于治疗过敏性和炎性疾病状态。本发明的化合物具有结构（I），其中M为氢，药学上可接受的阳离子或药学上可接受的代谢裂解基团; p和q独立为零或一个，条件是（i）p和q不能都相同; （ii）当p为1且q为0时，R选自氢，1至12个碳原子的直链或支链烷基和3至8个碳原子的环烷基; 和（iii）当p为0且q为1时，R选自氢，1至12个碳原子的烷基，3至8个碳原子的环烷基和-NR 1 R 2。 L1是直接键或选自1-6个碳原子的烷基，1至6个碳原子的亚烷基，和2至6个碳原子的炔基; L2是直接键或1-6个碳原子的烷基; Z选自氢，1至6个碳原子的烷基和1至6个碳原子的卤代烷基; 并且A是任选取代的碳环或杂环芳基，芳烷基或芳氧基。

9. 发明申请

WO1990012008A1 UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS 审中-公开
标题翻译：基于尿素的LIPOXYGENASE抑制化合物
公开(公告)号：WO1990012008A1
公开(公告)日：1990-10-18
申请号：PCT/US1990001488
申请日：1990-03-20
申请人： ABBOTT LABORATORIES , BROOKS, Dee, W. , STEWART, Andrew, O. , SUMMERS, James, B. , KERKMAN, Daniel, J. , MARTIN, Jonathan, G.
发明人： ABBOTT LABORATORIES
IPC分类号： C07D331/00
CPC分类号： C07D409/04 , C07C275/64 , C07C323/47 , C07D333/36 , C07D335/08 , C07D409/06 , C07D409/12
摘要： Substituted phenyl, naphthyl, and thienyl N-hydroxy urea compounds form a class of potent inhibitors of 5- and 12-lipoxygenase and are thus useful compounds in the treatment of inflammatory disease states where leukotrienes and other products of lipoxygenase enzyme activity are implicated.
摘要翻译：取代的苯基，萘基和噻吩基N-羟基脲化合物形成一类5-和12-脂氧合酶的有效抑制剂，因此是治疗其中涉及白细胞三烯和其它脂氧合酶活性产物的炎性疾病状态的有用化合物。

10. 发明申请

WO2016040862A3 INTEGRATION OF AUXILIARY SENSORS WITH POINT CLOUD-BASED HAPTIC RENDERING AND VIRTUAL FIXTURES 审中-公开
标题翻译：辅助传感器与基于点云的HAPTIC渲染和虚拟工具的整合
公开(公告)号：WO2016040862A3
公开(公告)日：2016-09-29
申请号：PCT/US2015049781
申请日：2015-09-11
申请人： CHIZECK HOWARD JAY , HUANG KEVIN , RYDEN FREDRIK , STEWART ANDREW
发明人： CHIZECK HOWARD JAY , HUANG KEVIN , RYDEN FREDRIK , STEWART ANDREW
IPC分类号： B25J9/16 , G06F3/00 , G06F3/01
CPC分类号： G06T17/00 , G05B2219/40
摘要： Apparatus and methods for generating virtual environment displays based on a group of sensors are provided. A computing device can receive first data about an environment from a first group of one or more sensors. The computing device can model the environment as a virtual environment based on the first data. The computing device can determine whether to obtain additional data to model the environment. After determining to obtain additional data to model the environment, the computing device can: receive second data about the environment, and model the environment as the virtual environment based on at least the second data. The computing device can generate a display of the virtual environment.
摘要翻译：提供了用于基于一组传感器生成虚拟环境显示的设备和方法。计算设备可以从第一组一个或多个传感器接收关于环境的第一数据。计算设备可以基于第一数据将环境建模为虚拟环境。计算设备可以确定是否获得附加数据以对环境建模。在确定获得附加数据以对环境建模之后，计算设备可以：接收关于环境的第二数据，并且基于至少第二数据将环境建模为虚拟环境。计算设备可以生成虚拟环境的显示。

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