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1. 发明申请

WO2012036744A3 IMPROVED PREPARATION METHODS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS 审中-公开
公开(公告)号：WO2012036744A3
公开(公告)日：2012-03-22
申请号：PCT/US2011/001600
申请日：2011-09-16
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. , WANG, Huisun , ST. JUDE MEDICAL, INC.
发明人： WANG, Huisun
IPC分类号： A61F2/84
摘要： A delivery device (10) for a collapsible prosthetic heart valve (6) includes a support shaft (21) around which a compartment (23) is defined, an inner shaft (26) extending through the support shaft and adapted to slide relative to the support shaft along a longitudinal axis thereof, the inner shaft having a lumen therethrough, and a distal sheath (24) operatively connected at a distal end to the inner shaft and slidable therewith. The compartment may receive the valve in an assembled condition, and may be selectively covered and uncovered by the distal sheath. A first flow path (c) may provide flow communication between the lumen of the inner shaft and the compartment.

2. 发明申请

WO2012036741A2 STAGED DEPLOYMENT DEVICES AND METHODS FOR TRANSCATHETER HEART VALVE DELIVERY 审中-公开
标题翻译：分段部署装置和方法用于运输心脏瓣膜输送
公开(公告)号：WO2012036741A2
公开(公告)日：2012-03-22
申请号：PCT/US2011/001597
申请日：2011-09-16
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. , KNIPPEL, Bradley, C. , WANG, Huisun , THOMAS, Ralph, J. , DALY, Jacob, J. , ST. JUDE MEDICAL, INC.
发明人： KNIPPEL, Bradley, C. , WANG, Huisun , THOMAS, Ralph, J. , DALY, Jacob, J.
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/95 , A61F2/962 , A61F2/966 , A61F2002/9517 , A61F2002/9534
摘要： A delivery device for a collapsible heart valve includes an operating handle and a catheter assembly. The operating handle includes a frame defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, and a coupler having locked and unlocked conditions, the coupler being operatively connected to the carriage assembly for movement therewith. The catheter assembly includes a shaft around which a valve receiving compartment is defined, the shaft being operatively connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly for movement therewith between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve.
摘要翻译：用于可折叠心脏瓣膜的递送装置包括操作手柄和导管组件。操作手柄包括限定其中的移动空间的框架，可在移动空间内沿纵向方向移动的滑架组件和具有锁定和解锁状态的联接器，联接器可操作地连接到滑架组件以与其一起运动。所述导管组件包括轴，围绕所述轴限定了阀接收室，所述轴可操作地连接到所述框架或所述托架组件中的一个，以及可操作地连接到所述托架组件的远侧护套，用于在适于维持隔室中的阀门和适于完全展开阀门的开启状态。

3. 发明申请

WO2012036740A2 RETAINERS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS 审中-公开
标题翻译：传送器心脏传送系统的保持器
公开(公告)号：WO2012036740A2
公开(公告)日：2012-03-22
申请号：PCT/US2011/001596
申请日：2011-09-16
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. , WANG, Huisun , GLAZIER, Valerie, J. , DALY, Jacob, J. , ST. JUDE MEDICAL, INC.
发明人： WANG, Huisun , GLAZIER, Valerie, J. , DALY, Jacob, J.
IPC分类号： A61M25/08
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/966 , A61F2002/9665 , A61F2230/0054 , A61M2025/0681
摘要： A delivery device 10 for a collapsible prosthetic heart valve includes a catheter assembly 16 including a shaft 26 around which a compartment 23 is defined, the compartment 23 being adapted to receive the valve in an assembled condition, and a retainer 30 including a pusher 32 and a holder 34 adapted to retain a stent portion 106 of the valve. The catheter assembly 16 also includes a distal sheath 24 adapted to selectively cover and uncover the compartment 23 and the valve, the distal sheath 24 extending around the shaft 26 at least when the distal sheath 24 covers the compartment 23. The pusher 32 includes one or more recesses 40 in a retention edge 33 thereof, each recess 40 being adapted to receive a junction 107 at an end of the stent portion 106 of the valve. The holder 34 includes one or more elongated ribs 50, each rib 50 being adapted to fit into a cell opening 108 of the stent portion 106 of the valve.
摘要翻译：用于可折叠人造心脏瓣膜的输送装置10包括导管组件16，导管组件16包括轴26，隔室23围绕该轴26限定，隔室23适于在组装状态下接收瓣膜，以及包括推动器32和适于保持瓣膜的支架部分106的保持器34的保持器30。至少当远侧护套24覆盖隔室23时，导管组件16还包括适于选择性地覆盖和露出隔室23和瓣膜的远侧护套24，远侧护套24围绕轴26延伸。推动器32包括一个或在其保持边缘33中具有更多凹部40，每个凹部40适于在瓣膜的支架部分106的端部处接收接合点107。保持器34包括一个或多个细长肋50，每个肋50适于装配到瓣膜的支架部分106的细胞开口108中。

4. 发明申请

WO2012106010A2 BLUNT ENDED STENT FOR PROSTHETIC HEART VALE 审中-公开
公开(公告)号：WO2012106010A2
公开(公告)日：2012-08-09
申请号：PCT/US2011/048963
申请日：2011-08-24
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIDVISION, INC. D/B/A ST. JUDE MEDICAL, CARDIOVASCULAR DIVISION , ALKHATIB, Yousef, F. , BRAIDO, Peter, Nicholas , BENSON, Thomas, M.
发明人： ALKHATIB, Yousef, F. , BRAIDO, Peter, Nicholas , BENSON, Thomas, M.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2002/9517 , A61F2002/9534 , A61F2220/0075 , A61F2230/0013 , A61F2250/0039
摘要： A collapsible prosthetic heart valve (100) includes a stent (102) and a valve assembly (104). The stent has a proximal end and a distal end and includes a plurality of struts (114). The struts have free ends (615, 625) configured to inhibit tissue penetration. The valve assembly, including a plurality of leaflets (108), is disposed within the stent.
摘要翻译：可折叠假体心脏瓣膜（100）包括支架（102）和阀组件（104）。支架具有近端和远端，并且包括多个支柱（114）。支柱具有配置成抑制组织穿透的自由端（615,625）。包括多个小叶（108）的瓣膜组件设置在支架内。

5. 发明申请

WO2012036742A3 ASSEMBLY AND METHOD FOR LOADING A SELF-EXPANDING COLLAPSIBLE HEART VALVE 审中-公开
公开(公告)号：WO2012036742A3
公开(公告)日：2012-03-22
申请号：PCT/US2011/001598
申请日：2011-09-16
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. , JOHNSON, Michael, A. , GLAZIER, Valerie, J. , WANG, Huisun , ST. JUDE MEDICAL, INC.
发明人： JOHNSON, Michael, A. , GLAZIER, Valerie, J. , WANG, Huisun
IPC分类号： A61F2/24 , B23P19/00
摘要： An assembly (200) for collapsing a prosthetic heart valve includes a compression member (202) and a pusher member (204). The compression member has a first open (208) end with a first diameter, a second open (210) end with a second diameter less than the first diameter, and a tapered wall (206) between the first open end and the second open end. The pusher member (204) has a base (232) adapted to engage an end of the valve. The pusher member and the compression member are movable relative to one another between an initial position in which the base of the pusher member is relatively far from the first open end of the compression member and an operative position in which the base of the pusher member is relatively close to the first open end of the compression member. Movement of the pusher and compression members from the initial position to the operative position radially compresses the valve.

6. 发明申请

WO2012027487A3 REPOSITIONING OF PROSTHETIC HEART VALVE AND DEPLOYMENT 审中-公开
公开(公告)号：WO2012027487A3
公开(公告)日：2012-03-01
申请号：PCT/US2011/048989
申请日：2011-08-24
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. D/B/A ST. JUDE MEDICAL, CARDIOVASCULAR DIVISION , ALKHATIB, Yousef, F. , BRAIDO, Peter, Nicholas
发明人： ALKHATIB, Yousef, F. , BRAIDO, Peter, Nicholas
IPC分类号： A61F2/24
摘要： A collapsible prosthetic heart valve (200) includes a stent (202) and a valve assembly (204). The stent (202) has an annulus section (240) with a relatively small cross-section, and an aortic section (242) with a relatively large cross-section. The valve assembly (204), including a cuff (206) and a plurality of leaflets (208), is secured to the stent (202) in the annulus section (240) such that the valve assembly (204) can be entirely deployed in the native valve annulus and function as intended while at least a portion of the aortic section (242) is held by the delivery device (1010) in a manner that allows for resheathing. The configuration of the prosthetic valve (200) is such that the valve leaflets (208) can fully coapt and the valve (200) can function properly even when the stent (202) and/or valve assembly (204) become distorted upon deployment or use.

7. 发明申请

WO2013166356A2 DEVICES AND METHODS FOR TRANSCATHETER HEART VALVE DELIVERY 审中-公开
标题翻译：用于输送心脏瓣膜输送的装置和方法
公开(公告)号：WO2013166356A2
公开(公告)日：2013-11-07
申请号：PCT/US2013/039407
申请日：2013-05-03
申请人： ST. JUDE MEDICAL, INC. , ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： MORRIS, Benjamin E. , FURNISH, Gregory R. , BIELEFELD, Eric E. , THOMAS, Ralph J. , LE, Khoi A. , GLAZIER, Valerie J. , KNIPPEL, Bradley C.
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/962 , A61F2002/9517
摘要： A delivery device for a collapsible prosthetic heart valve includes an operating handle and a catheter assembly. The operating handle may include a housing defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, a deployment actuator coupled to the housing and rotatable relative to the housing, and a coupling assembly rotationally fixed to the deployment actuator. The catheter assembly may include a first shaft around which a compartment is defined and a distal sheath operatively connected to the carriage assembly. Movement of the carriage assembly in the longitudinal direction in the movement space may move the distal sheath between the closed condition and the open condition. The coupling assembly may have an engaged position in which rotation of the deployment actuator moves the carriage assembly, and a disengaged position in which rotation of the deployment actuator does not move the carriage assembly.
摘要翻译：用于可折叠假体心脏瓣膜的递送装置包括操作手柄和导管组件。操作手柄可以包括限定其中的移动空间的壳体，可在移动空间内沿纵向方向移动的滑架组件，联接到壳体并相对于壳体可旋转的展开致动器，以及旋转地固定到展开致动器。导管组件可以包括第一轴，围绕所述第一轴限定隔室，远侧护套可操作地连接到托架组件。滑架组件在运动空间中的纵向移动可以使远侧护套在关闭状态和打开状态之间移动。联接组件可以具有接合位置，其中展开致动器的旋转使托架组件移动，并且分离位置，其中展开致动器的旋转不移动托架组件。

8. 发明申请

WO2012106011A1 LEAFLET SUTURING TO COMMISSURE POINT FOR PROSTHETIC HEART VALVE 审中-公开
标题翻译： LEAFLUR FOR TO COMMISSURE POINT FOR PROSTHETIC HEART VALVE
公开(公告)号：WO2012106011A1
公开(公告)日：2012-08-09
申请号：PCT/US2011/048967
申请日：2011-08-24
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. D/B/A ST. JUDE MEDICAL, CARDIOVASCULAR DIVISION , ALKHATIB, Yousef, F. , BRAIDO, Peter, Nicholas
发明人： ALKHATIB, Yousef, F. , BRAIDO, Peter, Nicholas
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2/2436 , A61F2/95 , A61F2002/9517 , A61F2002/9534 , A61F2220/0075 , A61F2230/0013 , A61F2250/0039
摘要： A collapsible prosthetic heart valve (100) includes a collapsible and expandable stent (102) and a collapsible and expandable valve assembly (104). The stent has a proximal end and a distal end. A plurality of commissure points (116) is disposed on the stent. The valve assembly is disposed within the stent and includes a plurality of leaflets (108). Each leaflet has a free edge (505). An end portion (724a, 724b) of the free edge of each leaflet is folded and sutured (730a, 730b) to a corresponding one of the plurality of the commissure points.
摘要翻译：可折叠假体心脏瓣膜（100）包括可折叠和可扩张的支架（102）和可折叠和可膨胀的阀组件（104）。支架具有近端和远端。多个连合点（116）设置在支架上。瓣膜组件设置在支架内并且包括多个传单（108）。每个小叶都有一个自由边（505）。每个小叶的自由边缘的端部（724a，724b）折叠并缝合（730a，730b）到多个连合点中的相应的一个。

9. 发明申请

WO2012039748A2 DELIVERY DEVICE HAVING A CURVED SHAFT AND A STRAIGHTENING MEMBER FOR TRANSCATHETER AORTIC VALVE IMPLANTATION 审中-公开
标题翻译：具有弯曲轴的输送装置和用于行驶室动力阀植入物的连接构件
公开(公告)号：WO2012039748A2
公开(公告)日：2012-03-29
申请号：PCT/US2011/001595
申请日：2011-09-16
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. , WANG, Huisun , THOMAS, Ralph, J. , ST. JUDE MEDICAL, INC.
发明人： WANG, Huisun , THOMAS, Ralph, J.
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2250/0018 , A61F2250/0019 , A61F2250/0029 , A61M25/0041 , A61M25/01 , A61M2025/0004
摘要： A delivery device may generally include a support member, a distal sheath, an outer shaft and a strengthening member. The support member is adapted to hold a prosthetic heart valve. The distal sheath is slidable relative to the support member between a first position in which the distal sheath is adapted to maintain the prosthetic heart valve in a collapsed condition, and a second position in which the distal sheath is adapted to expose the prosthetic heart valve. The outer shaft is connected to the distal sheath and has a curved portion. The straightening member is slidable on the outer shaft between a proximal position in which the straightening member does not cover the curved portion of the outer shaft, and a distal position in which the straightening member covers and substantially straightens at least a portion of the curved portion of the outer shaft.
摘要翻译：输送装置通常可以包括支撑构件，远侧鞘，外轴和加强构件。支撑构件适于保持假体心脏瓣膜。远侧护套可在第一位置和第二位置之间相对于支撑构件滑动，在第一位置，远侧护套适于将假体心脏瓣膜保持在折叠状态，以及第二位置，远端护套适于暴露假体心脏瓣膜。外轴与远端护套相连，并具有弯曲部分。矫直构件可以在外轴上在矫正构件不覆盖外轴的弯曲部分的近端位置和矫直构件覆盖的远侧位置之间滑动，并且基本上拉直弯曲部分的至少一部分的外轴。

10. 发明申请

WO2022186978A1 FLEXIBLE ELECTRONIC CIRCUIT FOR ULTRASOUND CATHETERS 审中-公开
公开(公告)号：WO2022186978A1
公开(公告)日：2022-09-09
申请号：PCT/US2022/016402
申请日：2022-02-15
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： LUPOTTI, Fermin , BLANCK, Arthur G.
IPC分类号： A61B90/00
摘要： A flexible electronic circuit, as may be used in an intravascular catheter, includes a flexible substrate having opposing first and second surfaces, one or more recesses into the first surface, one or more localization elements respectively disposed within the recesses, and a conductive connector pad on the substrate. Additional components, such as thermistors and ultrasound transducers, may also be mounted to the substrate.

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