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1. 发明申请

WO2005065911A1 PROCESS FOR MANUFACTURING A PROSTHETIC JOINT 审中-公开
标题翻译：制造接头的方法
公开(公告)号：WO2005065911A1
公开(公告)日：2005-07-21
申请号：PCT/NL2005/000005
申请日：2005-01-07
申请人： DSM IP ASSETS B.V. , MARISSEN, Roelof , SMIT, Leo , SNIJDER, Carina, Sacha
发明人： MARISSEN, Roelof , SMIT, Leo , SNIJDER, Carina, Sacha
IPC分类号： B29C43/00
CPC分类号： B29C43/006 , B29C43/003 , B29K2223/0683 , B29L2031/7532
摘要： The application relates to a process for manufacturing a prosthetic joint with at least one loaded surface which consists at least partially of polyethylene, comprising compressing one or more layers of a woven fabric of drawn gel-spun polyethylene fibres into the desired shape in a hollow mould part using a plug at a pressure of at least 0.05 MPa and at a temperature of between 120 and 165°C and below the crystalline melting point of the polyethylene at the prevailing temperature and pressure, without a matrix material being present, and at least the woven fabric in a layer situated on a loaded surface comprising at least 90wt % of fibres with a titre of at most 1000 denier, and to a prosthetic joint with a crease-free surface.
摘要翻译：本申请涉及一种用于制造具有至少部分由聚乙烯组成的至少一个加载表面的假体关节的方法，包括将拉伸的凝胶纺丝的聚乙烯纤维的一层或多层织物在中空模具中压缩成所需形状在不存在基质材料的情况下，使用塞子的压力为至少0.05MPa，温度为120至165℃且低于聚乙烯的结晶熔点，并且至少织物在位于包含至少90重量％的至多1000旦尼尔的纤维的负载表面的层中，以及具有无折痕表面的假体关节。

2. 发明申请

WO2010100267A1 SPINAL FUSION CAGE 审中-公开
标题翻译：脊柱融合笼
公开(公告)号：WO2010100267A1
公开(公告)日：2010-09-10
申请号：PCT/EP2010/052854
申请日：2010-03-05
申请人： DSM IP ASSETS B.V. , OBRIGKEIT, Darren Donald , KOENEN, Jacob , SCHUMANN, Detlef Olaf Alexander , SMIT, Leo
发明人： OBRIGKEIT, Darren Donald , KOENEN, Jacob , SCHUMANN, Detlef Olaf Alexander , SMIT, Leo
IPC分类号： A61L27/18 , A61F2/44 , A61L27/56
CPC分类号： A61F2/4455 , A61B17/86 , A61F2002/30014 , A61F2002/30016 , A61F2002/30448 , A61F2002/3097 , A61F2220/005 , A61F2250/0018 , A61F2250/0019 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61L27/18 , A61L27/56 , A61L2430/38 , C08L67/02
摘要： The invention is directed to a spinal fusion cage for implantation between two adjacent vertebrae, wherein the total cage has, under a load, a maximum compression that is higher than 0.05% of the original height of the spinal fusion cage and the maximum compression does not change the structural integrity of the cage.
摘要翻译：本发明涉及一种用于在两个相邻椎骨之间植入的脊柱融合器，其中总保持架在负载下具有高于脊柱融合器的原始高度的0.05％的最大压缩，并且最大压缩不改变笼子的结构完整性。

3. 发明申请

WO2009109645A3 LOAD-BEARING BONE IMPLANT COMPRISING A THERMOPLASTIC ELASTOMER 审中-公开
公开(公告)号：WO2009109645A3
公开(公告)日：2009-09-11
申请号：PCT/EP2009/052643
申请日：2009-03-05
申请人： DSM IP Assets B.V. , OBRIGKEIT, Darren Donald , SMIT, Leo
发明人： OBRIGKEIT, Darren Donald , SMIT, Leo
IPC分类号： A61L27/14
摘要： Disclosed is a load-bearing bone implant of a type suitable for permanent implantation. The implant is made of a thermoplastic elastomer comprising a hard phase and soft phase, wherein the hard phase comprises a polymer chosen from the group consisting of polyester, polyamide, polystyrene, polyacrylate and polyolefin and the soft phase comprises a polymer chosen from the group consisting of polyether, polyester, polyacrylate, polyolefin and polysiloxane.

4. 发明申请

WO2006010522A1 ELONGATED SURGICAL REPAIR PRODUCT BASED ON UHMWPE FILAMENTS 审中-公开
标题翻译：基于超高分子量聚乙烯纤维的长期手术修复产品
公开(公告)号：WO2006010522A1
公开(公告)日：2006-02-02
申请号：PCT/EP2005/007817
申请日：2005-07-14
申请人： DSM IP ASSETS B.V. , SMIT, Leo
发明人： SMIT, Leo
IPC分类号： A61L17/10
CPC分类号： D07B1/025 , A61L17/04 , A61L17/10 , D07B5/12 , D07B2205/2014 , D07B2801/10 , D07B2801/22
摘要： The invention relates to an elongated surgical repair product comprising an elongated member of core-sheath structure, wherein the core contains a plurality of high-strength ultra-high molar mass polyethylene (UHMWPE) filaments, and wherein the elongated member has a UHMWPE sheath that is substantially nonporous. This product combines high tensile strength, good flexibility and favourable knotting characteristics. The invention also relates to a process of making said elongated surgical repair product, comprising a step wherein an elongated precursor member containing a plurality of UHMWPE filaments is subjected to a heat treatment while keeping the filaments under tension.
摘要翻译：本发明涉及一种细长的外科修复产品，其包括芯 - 鞘结构的细长构件，其中所述芯包含多个高强度超高摩尔质量聚乙烯（UHMWPE）长丝，并且其中所述细长构件具有UHMWPE护套，基本上是无孔的。该产品结合了高抗拉强度，良好的柔韧性和良好的打结特性。本发明还涉及一种制备所述细长手术修复产品的方法，包括其中包含多个UHMWPE细丝的细长前体构件在保持细丝处于张力的同时进行热处理的步骤。

5. 发明申请

WO2004053212A1 PROCESS FOR MAKING AND PROCESS FOR CONVERTING POLYOLEFIN FIBRES 审中-公开
标题翻译：制造和处理聚烯烃纤维的方法
公开(公告)号：WO2004053212A1
公开(公告)日：2004-06-24
申请号：PCT/NL2003/000872
申请日：2003-12-09
申请人： DSM IP ASSETS B.V. , SMIT, Leo , SIMMELINK, Joseph, Arnold, Paul, Maria , NIELABA, Leonard, Josef, Arnold
发明人： SMIT, Leo , SIMMELINK, Joseph, Arnold, Paul, Maria , NIELABA, Leonard, Josef, Arnold
IPC分类号： D01F6/04
CPC分类号： D01F6/04 , Y10T428/29 , Y10T428/2933 , Y10T428/2967
摘要： The invention relates to a process for making a multi-filament polyethylene yarn via a gel-spinning process, wherein a spin finish is applied at least once in an amount of 0,1-10 mass % based on the filament, to a filament that contains less than 50 mass % of solvent; the spin finish comprising at least 95 mass % of at least one volatile compound having a boiling point at 0,1 MPa pressure of from 30 to 250 °C; and the spin finish is subsequently removed by exposing the filament to a temperature of below the melting temperature of the filament. With this process a yarn is made that has a very low amount of residues on the surface of the fibres, without the need for a washing or extraction step, showing good mechanical properties, and very suited for e.g. biomedical applications. The invention further relates to a process for converting polyolefin fibres into a semi-finished or end-use product. The invention also concerns a polyethylene yarn and a semi-finished or end-use product obtainable by said processes, as well as to the use of thereof in biomedical applications.
摘要翻译：本发明涉及一种通过凝胶纺丝法制造复丝聚乙烯纱线的方法，其中旋涂完成剂以至少一次量为基于丝丝的质量百分含量为0.1质量％的量施用于长丝含有少于50质量％的溶剂; 旋涂完成包含至少95质量％的沸点为0.1MPa压力为30至250℃的至少一种挥发性化合物; 然后通过将细丝暴露于低于丝的熔化温度的温度来除去旋涂。通过该方法，在纤维表面上制备具有非常少量的残留物的纱线，而不需要洗涤或提取步骤，显示出良好的机械性能，并且非常适合于例如，生物医学应用。本发明还涉及将聚烯烃纤维转变成半成品或最终用途产品的方法。本发明还涉及可通过所述方法获得的聚乙烯纱线和半成品或最终用途产品，以及其在生物医学应用中的用途。

6. 发明申请

WO2009109645A2 LOAD-BEARING BONE IMPLANT COMPRISING A THERMOPLASTIC ELASTOMER 审中-公开
标题翻译：包含热塑性弹性体的承载骨移植物
公开(公告)号：WO2009109645A2
公开(公告)日：2009-09-11
申请号：PCT/EP2009052643
申请日：2009-03-05
申请人： DSM IP ASSETS BV , OBRIGKEIT DARREN DONALD , SMIT LEO
发明人： OBRIGKEIT DARREN DONALD , SMIT LEO
IPC分类号： A61L27/18
CPC分类号： A61L27/18 , C08L69/005
摘要： Disclosed is a load-bearing bone implant of a type suitable for permanent implantation. The implant is made of a thermoplastic elastomer comprising a hard phase and soft phase, wherein the hard phase comprises a polymer chosen from the group consisting of polyester, polyamide, polystyrene, polyacrylate and polyolefin and the soft phase comprises a polymer chosen from the group consisting of polyether, polyester, polyacrylate, polyolefin and polysiloxane.
摘要翻译：公开了一种适用于永久植入的承载骨植入物。植入物由包含硬相和软相的热塑性弹性体制成，其中硬相包含选自聚酯，聚酰胺，聚苯乙烯，聚丙烯酸酯和聚烯烃的聚合物，软相包含选自以下的聚合物：的聚醚，聚酯，聚丙烯酸酯，聚烯烃和聚硅氧烷。

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