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1. 发明申请

WO2006006751A1 A COMPOSITION COMPRISING PURIFIED EXTRACT OF WILD GINSENG HAVING NEURONAL CELL PROTECTING ACTIVITY 审中-公开
标题翻译：包含具有神经细胞保护活性的金山纯化提取物的组合物
公开(公告)号：WO2006006751A1
公开(公告)日：2006-01-19
申请号：PCT/KR2004/001942
申请日：2004-08-02
申请人： SEOCKSANTEO MEDICAL CO., LTD. , PARK, Yong Jin , SHIM, In Sop , SONG, Gyu Yong
发明人： PARK, Yong Jin , SHIM, In Sop , SONG, Gyu Yong
IPC分类号： A61K35/78
CPC分类号： A61K36/258
摘要： The present invention relates to a use of a purified extract prepared by the method comprising the steps consisting of; subjecting the wild ginseng material to distillation extracting method with extracting solvent repeatedly; freezing the distilled extract to obtain frozen purified extract; thawing the extract and filtrating to obtain purified extract for the preparation of a pharmaceutical composition for the treatment and prevention of degenerative brain disease by protecting neuronal cell in human or mammal, and a composition comprising the same prepared by inventive method. The composition have potent neuronal cell protective activity, therefore, it can be used as the therapeutics for treating and preventing neuro-degenerative brain diseases caused by neuronal cell such as death stroke, apoplexy, dementia, Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease, Pick's disease and Creutzfeld-Jakob's disease and the like.
摘要翻译：本发明涉及通过包括以下步骤的方法制备的纯化提取物的用途：将野参人参材料进行蒸馏提取，反复萃取溶剂; 冷冻蒸馏提取物，得到冷冻纯化提取物; 解冻提取物并过滤以获得纯化的提取物，用于制备用于通过保护人或哺乳动物中的神经元细胞来治疗和预防退行性脑病的药物组合物，以及包含通过本发明方法制备的组合物的组合物。该组合物具有有效的神经元细胞保护活性，因此可用作治疗和预防神经元细胞如死亡中风，中风，痴呆，阿尔茨海默病（AD），帕金森病（PD）），亨廷顿疾病，皮克病和克雅氏病等。

2. 发明申请

WO2009091130A2 COMPOSITION FOR PREVENTION AND TREATMENT OF THE DEMENTIA 审中-公开
标题翻译：用于预防和治疗感染的组合物
公开(公告)号：WO2009091130A2
公开(公告)日：2009-07-23
申请号：PCT/KR2008007751
申请日：2008-12-29
申请人： PURIMED CO LTD , BAE HYUN SU , KANG MOON KYU , KIM JAE YOON , LEE NA YOUN , KIM YOUNG EUN , SHIM IN SOP
发明人： BAE HYUN SU , KANG MOON KYU , KIM JAE YOON , LEE NA YOUN , KIM YOUNG EUN , SHIM IN SOP
IPC分类号： A61K36/804
CPC分类号： A61K36/884 , A61K36/40 , A61K36/804 , A61K36/815 , A61K36/894 , A61K2300/00
摘要： Disclosed is a composition for prevention and treatment of neurodegenerative diseases associated with learning ability, memory retention and cognitive ability. In particular, disclosed is a composition for the prevention and treatment of dementia comprising a hot-water soluble extract of a herbal mixture (so-called 'Koo Gi Ji Hwang Tang' ) including steamed Rehmannia Radix, Lycium Fructus, Discoreae Rhizoma, Cornus Fructus, Hoelen, Moutan Cortex Radicis and Alismatis Rhizoma.
摘要翻译：公开了一种用于预防和治疗与学习能力，记忆保留和认知能力相关的神经变性疾病的组合物。具体地说，公开了一种预防和治疗痴呆的组合物，其包含含有蒸熟的地黄，枸杞，枸杞，枸杞子的草药混合物的热水溶性提取物（所谓的“古吉吉黄唐”），Hoelen，Moutan Cortex Radicis和Alismatis Rhizoma。

3. 发明申请

WO2006006750A1 A METHOD FOR PREPARING PURIFIED EXTRACT FROM WILD GINSENG SHOWING ANTICANCER ACTIVITY AND THE COMPOSITION COMPRISING THE SAME 审中-公开
标题翻译：一种用于制备来自野生姜黄素提取物的纯化提取物的方法和包含其的组合物
公开(公告)号：WO2006006750A1
公开(公告)日：2006-01-19
申请号：PCT/KR2004/001941
申请日：2004-08-02
申请人： SEOCKSANTEO MEDICAL CO., LTD. , PARK, Yong Jin , SHIM, In Sop , SONG, Gyu Yong
发明人： PARK, Yong Jin , SHIM, In Sop , SONG, Gyu Yong
IPC分类号： A61K35/78
CPC分类号： A61K36/258
摘要： The present invention relates to a method for preparing purified extract from wild ginseng showing anticancer activity such as inhibitory of cancer cell adherence, inhibitory of cancer cell metastasis and immunostimulating effect and a composition comprising the same prepared by inventive method. The composition have potent anticancer activity, therefore, it can be used as the therapeutics for treating and preventing various cancer diseases.
摘要翻译：本发明涉及一种制备野山参纯化提取物的方法，其显示抗癌活性，例如抑制癌细胞粘附，抑制癌细胞转移和免疫刺激作用，以及由本发明方法制备的组合物。该组合物具有有效的抗癌活性，因此可用作治疗和预防各种癌症疾病的治疗剂。

4. 发明申请

WO2006004294A1 EXTRACT OF NELUMBINIS SEMEN FOR THE TREATMENT OF DEPRESSSION, MEDICINAL COMPOSITE AN DHEALTH FOODS INCLUDING THE EXTRACT OF NELUMBINIS SEMEN 审中-公开
标题翻译：提取用于治疗呕吐，药物复合物的DHEALTH食品，包括NELUMBINIS SEMEN的提取物
公开(公告)号：WO2006004294A1
公开(公告)日：2006-01-12
申请号：PCT/KR2005/000932
申请日：2005-03-31
申请人： PURIMED CO., LTD. , BAE, Hyun-Su , KANG, Moon-Kyu , OH, Jung-Wan , CHO, Chong-Woon , KIM, Chang-Sook , LEE, Hwa-Jin , SHIM, In-Sop , JANG, Choon-Gon , CHOI, Hyun , KO, Eun-Jung , AN, Chang-Jun , KIM, Hyun-Taek , HONG, Moo-Chang , SHIN, Min-Kyu
发明人： BAE, Hyun-Su , KANG, Moon-Kyu , OH, Jung-Wan , CHO, Chong-Woon , KIM, Chang-Sook , LEE, Hwa-Jin , SHIM, In-Sop , JANG, Choon-Gon , CHOI, Hyun , KO, Eun-Jung , AN, Chang-Jun , KIM, Hyun-Taek , HONG, Moo-Chang , SHIN, Min-Kyu
IPC分类号： A61K35/78
CPC分类号： A61K36/62 , A23L33/105
摘要： Disclosed are an extract of Nelumbinis Semen (Nelumbo nucifera) having an antidepressive effect, and a pharmaceutical composition and a health food for treating depression, comprising the extract. The Nelumbinis Semen extract is prepared by extracting Nelumbinis Semen with hot water. Animal behavioral and biochemical studies revealed that the Nelumbinis Semen extract has very strong antidepressive activity and is safe to the body while reducing the side effects of conventional antidepressants. Thus, the Nelumbinis Semen extract is applicable to a composition and a health food for treating depression.
摘要翻译：公开了具有抗抑郁作用的Nelumbinis Semen（Nelumbo nucifera）的提取物，以及包含该提取物的药物组合物和用于治疗抑郁症的保健食品。 Nelumbinis Semen提取物通过用热水提取Nelumbinis Semen制备。动物行为和生物化学研究表明，奈洛卜精液提取物具有非常强的抗抑郁活性，对身体安全，同时减少常规抗抑郁药的副作用。因此，Nelumbinis Semen提取物适用于治疗抑郁症的组合物和保健食品。

5. 发明申请

WO2009091130A3 COMPOSITION FOR PREVENTION AND TREATMENT OF THE DEMENTIA 审中-公开
公开(公告)号：WO2009091130A3
公开(公告)日：2009-07-23
申请号：PCT/KR2008/007751
申请日：2008-12-29
申请人： PURIMED CO., LTD. , BAE, Hyun Su , KANG, Moon Kyu , KIM, Jae Yoon , LEE, Na Youn , KIM, Young Eun , SHIM, In Sop
发明人： BAE, Hyun Su , KANG, Moon Kyu , KIM, Jae Yoon , LEE, Na Youn , KIM, Young Eun , SHIM, In Sop
IPC分类号： A61K36/804
摘要： Disclosed is a composition for prevention and treatment of neurodegenerative diseases associated with learning ability, memory retention and cognitive ability. In particular, disclosed is a composition for the prevention and treatment of dementia comprising a hot-water soluble extract of a herbal mixture (so-called 'Koo Gi Ji Hwang Tang' ) including steamed Rehmannia Radix, Lycium Fructus, Discoreae Rhizoma, Cornus Fructus, Hoelen, Moutan Cortex Radicis and Alismatis Rhizoma.

6. 发明申请

WO2008140185A1 BELT WITH HEALTH MANAGEMENT FUNCTION 审中-公开
标题翻译：带健康管理功能
公开(公告)号：WO2008140185A1
公开(公告)日：2008-11-20
申请号：PCT/KR2008/001705
申请日：2008-03-27
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , KIM, Seunghwan , PARK, Sun-Hee , OH, Soo-Young , PYUN, Kwang-Ho , KIM, Kyung-Soo , SHIM, In-Sop , NA, Hyen-Oh , CHOI, Chang-Jin , KIM, Se-Hong
发明人： KIM, Seunghwan , PARK, Sun-Hee , OH, Soo-Young , PYUN, Kwang-Ho , KIM, Kyung-Soo , SHIM, In-Sop , NA, Hyen-Oh , CHOI, Chang-Jin , KIM, Se-Hong
IPC分类号： A41F9/00
CPC分类号： A61B5/02055 , A61B5/021 , A61B5/0402 , A61B5/0537 , A61B5/107 , A61B5/11 , A61B5/6831 , G06F19/00
摘要： A belt with a health management function includes a health information extraction module extracting health related information from various biomedical signals, a buckle housing the health information extraction module, and a strap connected to an end of the buckle. The health information extraction module includes a sensor module detecting various biomedical signals, and a process/extraction unit digitally processing the detected biomedical signals and extracting the health related information from the processed digital signals.
摘要翻译：具有健康管理功能的皮带包括从各种生物医学信号提取健康相关信息的健康信息提取模块，容纳健康信息提取模块的带扣，以及连接到该扣环的端部的绑带。健康信息提取模块包括检测各种生物医学信号的传感器模块，以及处理/提取单元，数字地处理检测到的生物医学信号，并从经处理的数字信号中提取健康相关信息。

7. 发明申请

WO2007083908A1 A METHOD FOR PREPARING DECURSINOL FROM ANGELICA GIGAS WITH HIGH YIELD 审中-公开
标题翻译：用于制备具有高YIELD的ANGELICA GIGAS的十二烷基磺酸的方法
公开(公告)号：WO2007083908A1
公开(公告)日：2007-07-26
申请号：PCT/KR2007/000251
申请日：2007-01-16
申请人： PARK, Yong Jin , KIM, Joo Hwan , KIM, Jin Sook , SONG, Gyu Yong , LEE, Jee Hyun , JEONG, Hye Gwang , KIM, Dong Hee , YUN, Mi Young , JIN, Wen Yi , SHIM, In Sop , CHOI, Yong Seok
发明人： PARK, Yong Jin , KIM, Joo Hwan , KIM, Jin Sook , SONG, Gyu Yong , LEE, Jee Hyun , JEONG, Hye Gwang , KIM, Dong Hee , YUN, Mi Young , JIN, Wen Yi , SHIM, In Sop , CHOI, Yong Seok
IPC分类号： C07D493/04 , A61K31/35
CPC分类号： C07D493/04
摘要： The present invention relates to a novel process for preparing decursinol (7-hydroxy-8,8-dimethyl-7,8-dihydro-6H-pyrano(3,2-)chromen-2-one) comprising the steps consisting of: extracting dried root of Angelica decursiva Fr. St, with water, lower alcohol or the mixture thereof, filtering and concentrating the filtrate to obtain the extract of root of Angelica decursiva Fr. St at 1st step; suspending and fractionating the extract with non-polar organic solvent selected from ether, chloroform, ethylacetate or acetone solvent to obtain the non-polar soluble extract at 2nd step; subjecting the non-polar soluble extract to basic hydrolysis with base selected from sodium hydroxide, potassium hydroxide, potassium carbonate or sodium carbonate to obtain hydrolyzed product at 3r step; neutralizing the solution with acid and recovering the hydrolyzed decursinol fraction from the solution with non-polar organic solvent selected from ether, chloroform, methylene chloride, ethylacetate or acetone at 4 step; purifying the fraction to obtain purposed decursinol with high-yield.
摘要翻译：本发明涉及一种制备前胡桃醇（7-羟基-8,8-二甲基-7,8-二氢-6H-吡喃并（3,2-）色烯-2-酮）的新方法，包括以下步骤：提取当归干根 St，用水，低级醇或其混合物，过滤并浓缩滤液，得到当归提取物。圣第一步; 用乙醚，氯仿，乙酸乙酯或丙酮溶剂中的非极性有机溶剂悬浮和分馏提取物，在第二步获得非极性可溶性提取物; 将非极性可溶性提取物用选自氢氧化钠，氢氧化钾，碳酸钾或碳酸钠的碱进行碱性水解，得到3r步骤的水解产物; 用酸中和溶液，并用4步的非极性有机溶剂从乙醚，氯仿，二氯甲烷，乙酸乙酯或丙酮中回收水解的前胡烯醇馏分; 纯化该级分以获得高产量的前胡椒醇。

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