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1. 发明申请

WO2011094579A3 MUSHROOM COMPOSITIONS AND METHODS FOR MAKING AND USING 审中-公开
标题翻译： MUSHROOM组合物和制备和使用的方法
公开(公告)号：WO2011094579A3
公开(公告)日：2011-09-29
申请号：PCT/US2011022976
申请日：2011-01-28
申请人： NEW CHAPTER INC , UNIV TEXAS , YANG PEIYING , NEWMAN ROBERT A , SCHULICK PAUL
发明人： YANG PEIYING , NEWMAN ROBERT A , SCHULICK PAUL
IPC分类号： A61K36/07
CPC分类号： A61K36/074 , A61K36/068 , A61K36/07 , A61K36/076 , A61K2300/00
摘要： The present subject matter relates to a novel mushroom composition and methods for making and using the same. In one aspect, the subject matter involves a composition comprising a combination of mushrooms or components derived from mushrooms selected from the group consisting of Reishi Ganoderma lucidum, Reishi Ganoderma lucidum, Cordyceps sinensis, Maitake Grifola frondosa, Shiitake Lentinula edodes, Poria cocos, Lion's Mane Hericium erinaceus, Mesima Phellinus linteus, Turkey Tail Coriolus Tramentes versicolor, Chaga Inonotus obliquus, and Chaga Inonotus obliquus. In some embodiments, the present subject matter relates to methods for modulating immune function, regulating the activity of lipoxygenases and cyclooxygenases, improving cardiovascular health, and/or inhibiting cell proliferation diseases and disorders. In one embodiment the composition provides a balancing of anti-inflammatory and pro-inflammatory function in an animal, including in humans.
摘要翻译：本发明涉及一种新颖的蘑菇组合物及其制备和使用方法。在一个方面，主题涉及一种组合物，其包含蘑菇或来自蘑菇的组分的组合，所述蘑菇或选自以下的蘑菇：灵芝灵芝，灵芝灵芝，冬虫夏草，山茱萸，叶螨，茯苓，狮子鬃 Hericium erinaceus，Mesima Phellinus linteus，Turkey Tail Coriolus Tramentes versicolor，Chaga Inonotus obliquus和Chaga Inonotus obliquus。在一些实施方案中，本主题涉及调节免疫功能，调节脂氧合酶和环加氧酶的活性，改善心血管健康和/或抑制细胞增殖疾病和病症的方法。在一个实施方案中，所述组合物在动物（包括人）中提供抗炎和促炎功能的平衡。

2. 发明申请

WO2011094579A2 MUSHROOM COMPOSITIONS AND METHODS FOR MAKING AND USING 审中-公开
标题翻译：蘑菇组合物及其制备和使用方法
公开(公告)号：WO2011094579A2
公开(公告)日：2011-08-04
申请号：PCT/US2011/022976
申请日：2011-01-28
申请人： NEW CHAPTER INC. , BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM , YANG, Peiying , NEWMAN, Robert, A. , SCHULICK, Paul
发明人： YANG, Peiying , NEWMAN, Robert, A. , SCHULICK, Paul
IPC分类号： A61K36/06 , A61P3/10 , A61P19/02 , A61P1/16 , A61P9/10 , A61P29/00 , A61P11/00 , A61P17/06 , A61P25/16
CPC分类号： A61K36/074 , A61K36/068 , A61K36/07 , A61K36/076 , A61K2300/00
摘要： The present subject matter relates to a novel mushroom composition and methods for making and using the same. In one aspect, the subject matter involves a composition comprising a combination of mushrooms or components derived from mushrooms selected from the group consisting of Reishi Ganoderma lucidum, Reishi Ganoderma lucidum, Cordyceps sinensis, Maitake Grifola frondosa, Shiitake Lentinula edodes, Poria cocos, Lion's Mane Hericium erinaceus, Mesima Phellinus linteus, Turkey Tail Coriolus Tramentes versicolor, Chaga Inonotus obliquus, and Chaga Inonotus obliquus. In some embodiments, the present subject matter relates to methods for modulating immune function, regulating the activity of lipoxygenases and cyclooxygenases, improving cardiovascular health, and/or inhibiting cell proliferation diseases and disorders. In one embodiment the composition provides a balancing of anti-inflammatory and pro-inflammatory function in an animal, including in humans.
摘要翻译：本发明的主题涉及一种新型蘑菇组合物及其制备和使用方法。在一个方面，本主题涉及一种组合物，其包含蘑菇或衍生自蘑菇的组分的组合，所述组合选自由灵芝灵芝，灵芝灵芝，冬虫夏草，Maitake灰树花，香菇香菇，茯苓，狮子鬃猴头菌，Mesima Phellinus linteus，土耳其Tail Coriolus Tramentes versicolor，Chaga Inonotus obliquus和Chaga Inonotus obliquus。在一些实施方案中，本主题涉及用于调节免疫功能，调节脂氧合酶和环氧合酶的活性，改善心血管健康和/或抑制细胞增殖疾病和病症的方法。在一个实施方案中，组合物提供动物（包括人类）中的抗炎和促炎功能的平衡。

3. 发明申请

WO2010138902A1 COMPOSITIONS AND METHODS FOR MODULATING LIPID COMPOSITION 审中-公开
标题翻译：用于调节脂肪组合物的组合物和方法
公开(公告)号：WO2010138902A1
公开(公告)日：2010-12-02
申请号：PCT/US2010/036712
申请日：2010-05-28
申请人： NEW CHAPTER INC. , BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM , NEWMAN, Robert, A. , YANG, Peiying , SCHULICK, Paul
发明人： NEWMAN, Robert, A. , YANG, Peiying , SCHULICK, Paul
IPC分类号： A61K36/00
CPC分类号： A61K36/53 , A61K35/60 , A61K45/06
摘要： The present subject matter relates to a novel herbal and oil composition and methods for modulating fatty acid composition and metabolism in an animal. In one aspect, the subject matter involves a composition comprising rosemary extract, oregano extract, and a polyunsaturated oil. In a particular embodiment, the polyunsaturated oil is fish oil or a derivative thereof. In some embodiments, the present subject matter relates to methods for modulating essential dietary fatty acid composition of lipoprotein particles or cell membranes, modulating essential fatty acid metabolism, regulating the activity of lipoxygenases and cyclooxygenases, improving cardiovascular health, and / or inhibiting cell proliferation diseases and disorders.
摘要翻译：本发明涉及用于调节动物脂肪酸组成和代谢的新颖的草药和油组合物和方法。在一个方面，主题涉及包含迷迭香提取物，牛至提取物和多不饱和油的组合物。在一个具体实施方案中，多不饱和油是鱼油或其衍生物。在一些实施方案中，本主题涉及调节脂蛋白颗粒或细胞膜的必需膳食脂肪酸组成，调节必需脂肪酸代谢，调节脂氧合酶和环加氧酶的活性，改善心血管健康和/或抑制细胞增殖疾病的方法和疾病。

4. 发明申请

WO2007041276A3 METHODS FOR MODULATING APOPTOSIS, CELLGROWTH, AND PROTEIN EXPRESSION WITH HERBAL COMPOSITIONS 审中-公开
公开(公告)号：WO2007041276A3
公开(公告)日：2007-04-12
申请号：PCT/US2006/038019
申请日：2006-09-29
申请人： NEW CHAPTER, INC. , NEWMARK, Thomas , BEMIS, Debra, L. , KATZ, Aaron, E. , SCHULICK, Paul
发明人： NEWMARK, Thomas , BEMIS, Debra, L. , KATZ, Aaron, E. , SCHULICK, Paul
IPC分类号： A61K36/06
摘要： The inventive subject matter relates to methods for modulating apoptosis, cell growth, and protein expression, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis , rosemary, green tea, huzhang, chinese goldthread, and barberry.

5. 发明申请

WO2007041276A2 METHODS FOR MODULATING APOPTOSIS, CELLGROWTH, AND PROTEIN EXPRESSION WITH HERBAL COMPOSITIONS 审中-公开
标题翻译：用草药组合物调节细胞凋亡，细胞生长和蛋白质表达的方法
公开(公告)号：WO2007041276A2
公开(公告)日：2007-04-12
申请号：PCT/US2006038019
申请日：2006-09-29
申请人： NEW CHAPTER INC , NEWMARK THOMAS , BEMIS DEBRA L , KATZ AARON E , SCHULICK PAUL
发明人： NEWMARK THOMAS , BEMIS DEBRA L , KATZ AARON E , SCHULICK PAUL
IPC分类号： A61K36/9068 , A61K36/9066
CPC分类号： A61K36/9066 , A61K36/29 , A61K36/53 , A61K36/539 , A61K36/704 , A61K36/718 , A61K36/82 , A61K36/9068 , A61K2300/00
摘要： The inventive subject matter relates to methods for modulating apoptosis, cell growth, and protein expression, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, chinese goldthread, and barberry.
摘要翻译：本发明主题涉及调节细胞凋亡，细胞生长和蛋白质表达的方法，其包括施用包含治疗有效量的迷迭香，姜黄，牛至和姜的超临界提取物的组合物; 和治疗有效量的圣罗勒，生姜，姜黄，黄芩，迷迭香，绿茶，虎杖，黄芩和小檗的水醇提取物。

6. 发明申请

WO2006138296A1 METHODS FOR MODULATING EICOSANOID METABOLISM 审中-公开
标题翻译：调节异黄酮代谢的方法
公开(公告)号：WO2006138296A1
公开(公告)日：2006-12-28
申请号：PCT/US2006/022967
申请日：2006-06-14
申请人： NEW CHAPTER, INC. , THE UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER , NEWMARK, Thomas , SCHULICK, Paul , NEWMAN, Robert , AGGARWAL, Bharat
发明人： NEWMARK, Thomas , SCHULICK, Paul , NEWMAN, Robert , AGGARWAL, Bharat
IPC分类号： A61K36/00 , A61K36/53 , A61K36/71 , A61K36/906
CPC分类号： A61K36/9066 , A61K36/29 , A61K36/53 , A61K36/539 , A61K36/704 , A61K36/718 , A61K36/82 , A61K36/9068 , A61K2300/00
摘要： The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.
摘要翻译：本发明主题涉及在有需要的动物的细胞中调节类花生酸代谢过程的方法，其包括向动物施用一定量的有效调节类二烷酸加氧酶活性的本发明组合物。具体地，本发明主题涉及通过施用一定量的有效调节脂氧合酶和环加氧酶的活性的本发明组合物来调节花生四烯酸代谢的方法。

7. 发明申请

WO2005056033A1 METHODS FOR TREATING PROSTATIC INTRAEPITHELIAL NEOPLASIA WITH HERBAL COMPOSITIONS 审中-公开
标题翻译：用草药组合物治疗前列腺内皮细胞的方法
公开(公告)号：WO2005056033A1
公开(公告)日：2005-06-23
申请号：PCT/US2004/040582
申请日：2004-12-03
申请人： NEW CHAPTER, INC. , NEWMARK, Thomas , SCHULICK, Paul , KATZ, Aaron
发明人： NEWMARK, Thomas , SCHULICK, Paul , KATZ, Aaron
IPC分类号： A61K35/78
CPC分类号： A61K36/9066 , A61K36/29 , A61K36/53 , A61K36/539 , A61K36/704 , A61K36/718 , A61K36/82 , A61K36/9068 , A61K2300/00
摘要： The inventive subject matter relates to methods for treating prostatic intraepithelial neoplasia, comprising composition comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis , rosemary, green tea, huzhang, Chinese goldthread, and barberry.
摘要翻译：本发明涉及用于治疗前列腺上皮内瘤变的方法，包括组合物，其包含施用包含治疗有效量的迷迭香，姜黄，牛至和姜的超临界提取物的组合物; 以及治疗有效量的圣罗勒，姜，姜黄，黄芩，迷迭香，绿茶，胡章，中国黄连和小檗碱的水醇提取物。

8. 发明申请

WO2005056032A1 METHODS FOR TREATING PROSTATE CANCER WITH HERBAL COMPOSITIONS 审中-公开
标题翻译：用草药组合物治疗前列腺癌的方法
公开(公告)号：WO2005056032A1
公开(公告)日：2005-06-23
申请号：PCT/US2004/040568
申请日：2004-12-03
申请人： NEW CHAPTER, INC. , NEWMARK, Thomas , SCHULICK, Paul , KATZ, Aaron
发明人： NEWMARK, Thomas , SCHULICK, Paul , KATZ, Aaron
IPC分类号： A61K35/78
CPC分类号： A61K36/82 , A61K36/185 , A61K36/42 , A61K36/53 , A61K36/889 , A61K36/906 , A61K2300/00
摘要： The inventive subject matter relates to methods for treating prostate cancer, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.
摘要翻译：本发明涉及用于治疗前列腺癌的方法，包括施用包含治疗有效量的迷迭香，姜黄，牛至和姜的超临界提取物的组合物; 以及治疗有效量的圣罗勒，姜，姜黄，黄芩，迷迭香，绿茶，胡章，中国黄连和小檗碱的水醇提取物。

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