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1. 发明申请

WO2012097770A8 METHOD AND DEVICE FOR TESTING TREATMENTS WHICH INTRODUCE ENERGY INTO OBJECTS 审中-公开
标题翻译：用于测试建筑物能源公司的方法和设备结束疗程组合
公开(公告)号：WO2012097770A8
公开(公告)日：2013-06-06
申请号：PCT/DE2011002080
申请日：2011-11-28
申请人： FRAUNHOFER GES FORSCHUNG , HAERTLING THOMAS , MAYER ANTON , OPITZ JOERG , SCHREIBER JUERGEN , DERENKO SUSAN , WETZEL CHRISTIANE
发明人： HAERTLING THOMAS , MAYER ANTON , OPITZ JOERG , SCHREIBER JUERGEN , DERENKO SUSAN , WETZEL CHRISTIANE
IPC分类号： G01N21/64 , G01T1/10
CPC分类号： G01N21/643 , A61L2/087 , A61L2/28 , A61L2202/24 , C21D1/54 , C21D8/1272 , C21D11/00 , C21D2201/05 , G01N21/6408
摘要： The invention relates to a method and device (10) for testing treatments (14) which introduce energy into objects (1), wherein the method comprises the following steps: bonding at least one chemical, optically luminescent compound (3) onto at least one indicator element (6) for testing the treatments (14), wherein at least one luminescence property of the chemical compound (3) can be changed; assigning at least one indicator element (6) to the object (1), wherein the indicator element (6) and the object (1) are simultaneously subjected to the same conditions of the energy-introducing treatment (14); changing the luminescence property of the chemical compound (3), wherein the level of the change to the luminescence property depends upon the energy-introducing treatment (14; irradiating (13) the chemical compound (3) with electromagnetic radiation directed onto the indicator (6) for excitation of the luminescence during the energy-introducing treatment or following the energy-introducing treatment (14) in order to demonstrate the instantaneous energy-introducing treatment (14) or the energy-introducing treatment (14) carried out; time-resolved and/or spectrally-resolved detection of electromagnetic radiation (12) emitted as a result of luminescence of the chemical compound of the indicator element (6) during the luminescence-emitting irradiation (13) or after the luminescence-emitting irradiation (13) is switched off; providing time-resolved and/or spectrally-resolved detection signals from a detector (5) to at least one evaluation unit (9) in which: - the detection signals (17) and reference signals (18) which are stored in a memory (16) and which consist of at least one previously determined reference value and/or at least one reference wavelength or of at least one reference wavelength spectrum are compared and - the energy-introducing treatment (14) carried out on the object (1) is demonstrably established; and displaying same in a display unit (15) after testing for the presence of at least one energy input (14) in the object (1) on the basis of the achieved changed luminescence property of the chemical compound (3).
摘要翻译：本发明涉及一种用于检查物体（1）的能量输入端的处理（14）的方法和设备（10），所述方法包括以下步骤： - 结合的至少一种化学，光学发光化合物（3）与至少一个指示器构件（6 ）来测试处理（14），其中所述化学化合物中的至少一个发光特性（3）是可变的， - 分配至少一个指示器构件（6）与所述对象（1），其中所述指示器构件（6）和所述对象（1）在同一时间在同一的能量输入端处理（14）的条件下被暴露， - 在化学化合物的发光变化（3），其特征在于，改变在能源输入端处理（14）取决于的发光水平， - 与所述化学化合物（3）的辐射（13）所述指示器元件（6）上引导电磁辐射为d时的发光的激励他能源压延治疗或用于检测所述能量一个杰出的目前的治疗（14）或能量一个未决处理（14）中，下面的能量处理（14）的输入 - 时间分辨和/或化学化合物的发光的结果的光谱分辨的检测（指示元件6的在lumineszenzauslösenden辐射期间）发射的电磁辐射（12）（13）或关断lumineszenzauslösenden照射（13），后 - 提供（通过从检测器5）的至少一个分析单元的时间分辨和/或spektralaufgelösten检测信号（9），在该携带·从至少一个预先确定的参考值和/或至少一个参考波长或至少一个参考波长光谱和·可证明的检测的检测信号（17）和在存储器（16）中存储的基准信号（18）之间的比较至少一个能量输入（14）的存在的检查后在所述对象（1）在发光所实现的变化的基础上，在显示单元（15）的显示 - 对象的恢复（1）能量的一个杰出的治疗进行/秒（14），和化学化合物（3）。

2. 发明申请

WO2010089147A8 SURFACE PLASMON RESONANCE SENSOR 审中-公开
标题翻译：表面等离子体共振传感器
公开(公告)号：WO2010089147A8
公开(公告)日：2010-10-07
申请号：PCT/EP2010000769
申请日：2010-02-08
申请人： FRAUNHOFER GES FORSCHUNG , OPITZ JOERG , SCHREIBER JUERGEN , GUBAREVICH TATIANA , LAPINA VICTORIA , BELYI VLADIMIR , KAZAK NIKOLAI , KROENING MICHAEL
发明人： OPITZ JOERG , SCHREIBER JUERGEN , GUBAREVICH TATIANA , LAPINA VICTORIA , BELYI VLADIMIR , KAZAK NIKOLAI , KROENING MICHAEL
IPC分类号： G01N21/55 , G01N33/543
CPC分类号： G01N21/554 , G01N33/54373 , Y10T436/143333
摘要： The application relates to a sensor using a gold layer (3) with embedded nanodiamonds (2) on which surface plasmon resonance (SPR) is used to detect target molecules (5).
摘要翻译：本申请涉及使用具有嵌入纳米金刚石（2）的金层（3）的传感器，其上使用表面等离子体共振（SPR）来检测目标分子（5）。

3. 发明申请

WO2012144696A1 PROSTATE CANCER DIAGNOSIS DEVICE USING FRACTAL DIMENSION VALUE 审中-公开
标题翻译：使用分数值的前列腺癌诊断装置
公开(公告)号：WO2012144696A1
公开(公告)日：2012-10-26
申请号：PCT/KR2011/005801
申请日：2011-08-09
申请人： IM CO., LTD. , FRAUNHOFER-GESELLSCHAFT , LEE, Sang Dae , KIM, Kyung Sik , BAIK, Jun Heum , KIM, Eunjung , HAN, Tae-Young , GERICH, Carola , ZEH, Christoph , HAERTLING, Thomas , OPITZ, Joerg , SCHREIBER, Juergen
发明人： LEE, Sang Dae , KIM, Kyung Sik , BAIK, Jun Heum , KIM, Eunjung , HAN, Tae-Young , GERICH, Carola , ZEH, Christoph , HAERTLING, Thomas , OPITZ, Joerg , SCHREIBER, Juergen
IPC分类号： A61B5/06 , A61B5/0275
CPC分类号： A61B1/307 , A61B1/043 , A61B5/0071 , A61B5/4381 , A61B5/7282 , G01N21/6486
摘要： The present invention relates to a prostate cancer diagnosis device including a semiconductor laser emitting an laser beam; an endoscope transmitting the laser beam to a biopsy tissue in a human body and receiving auto-fluorescence generated from the biopsy tissue; an optical unit transmitting the laser beam to the endoscope and receiving an auto-fluorescence generated from the biopsy tissue from the endoscope; a detection unit detecting the auto-fluorescence received by the optical unit and measuring intensity of a single photon corresponding to a single pulse to detect intensity of the time-dependent auto-fluorescence (hereinafter referred to as an auto-fluorescence measured value); and a diagnosis unit calculating fractal dimension values of the auto-fluorescence measured value using a fractal dimension algorithm, and a diagnosis method using the same.
摘要翻译：本发明涉及一种包含发射激光束的半导体激光器的前列腺癌诊断装置，将激光束传送到人体活检组织并接收从活检组织产生的自发荧光的内窥镜; 将所述激光束透射到所述内窥镜并从所述内窥镜接收从所述活检组织产生的自发荧光的光学单元; 检测单元，检测由光学单元接收的自动荧光，并测量与单个脉冲对应的单个光子的强度，以检测时间依赖性自动荧光的强度（以下称为自动荧光测量值）; 以及使用分维维数算法计算自动荧光测定值的分维数值的诊断部，以及使用其的诊断方法。

4. 发明申请

WO2009068023A2 ARRANGEMENT FOR OPTICAL MONITORING AND/OR DETECTION OF PHYSICAL AND/OR CHEMICAL MEASUREMENT VARIABLES 审中-公开
标题翻译：安排光学监测和/或确定物理和/或化学度量的
公开(公告)号：WO2009068023A2
公开(公告)日：2009-06-04
申请号：PCT/DE2008002047
申请日：2008-11-28
申请人： FRAUNHOFER GES FORSCHUNG , WILHELMI BERND , SCHREIBER JUERGEN , NEBEL DIETER
发明人： WILHELMI BERND , SCHREIBER JUERGEN , NEBEL DIETER
IPC分类号： G01N21/77 , G01N17/04
CPC分类号： G01N21/7703 , G01N2021/7713 , G01N2021/7716 , G01N2021/7726
摘要： The invention relates to an optical arrangement for monitoring and/or detection of physical and/or chemical measurement variables, wherein electromagnetic radiation is emitted by at least one radiation source and directed by an optical fiber towards at least one optical detector. The aim of the invention is to propose possibilities for an optical detection of physical and/or chemical influences or measurement variables that is simpler, more cost-effective, and more reliable. In the arrangement according to the invention, electromagnetic radiation is directed from a radiation source toward an optical detector by an optical fiber. At least one sensitive region is present on the optical fiber in which the material of the optical fiber has been replaced by a material or mixture of materials that is optically transparent, at least in the range of a wavelength of the electromagnetic radiation. At at least one measurement temperature and/or measurement wavelength, said sensitive region has the same optical refraction index as the replaced material or the deviation of the optical refraction index of the material or mixture of materials is less than the difference between the optical refraction indices of the core and jacket of the optical fiber and, at the sensitive region, a change occurs in the complex refraction index by a modification of the material or mixture of materials as a result of the physical and/or chemical influence acting on the optical fiber and a change occurs in the transmission and/or reflection of the electromagnetic radiation.
摘要翻译：本发明涉及一种用于从至少一个辐射源在所述电磁辐射发射的物理和/或化学计量值的监测和/或确定的光学布置，并通过光纤引导到至少一个光检测器。本发明的目的是提出一种用于物理和/或化学的影响或测量的变量的简化，更便宜，更可靠的光学检测的可能性。在发明的安排，从放射线源通过光纤到光检测器看到的电磁辐射被引导。在光纤是其中光纤的材料已取代的物质或/其是光学透明的电磁辐射的波长的区域中的至少一个混合物的至少一个敏感区域存在。至少一个测量温度和/或测量所述波长包括相同的光学折射率作为替换材料，或物质或组合物的光学折射率的偏差小于在所述芯和所述光纤的包层和敏感区域的光学折射率发生的差在复折射率的变化，通过与作用于所述光纤的物理和/或化学的影响力的结果的物质物质或混合物的变形，以及在传输和/或电磁辐射的反射的变化。

5. 发明申请

WO2012144695A1 PROSTATE CANCER DIAGNOSIS DEVICE USING FRACTAL DIMENSION VALUE 审中-公开
标题翻译：使用分数值的前列腺癌诊断装置
公开(公告)号：WO2012144695A1
公开(公告)日：2012-10-26
申请号：PCT/KR2011/005785
申请日：2011-08-09
申请人： IM CO., LTD. , LEE, Sang Dae , KIM, Kyung Sik , BAIK, Jun Heum , KIM, Eunjung , HAN, Tae-Young , GERICH, Carola , ZEH, Christoph , HAERTLING, Thomas , OPITZ, Joerg , SCHREIBER, Juergen , FRAUNHOFER-GESELLSCHAFT
发明人： LEE, Sang Dae , KIM, Kyung Sik , BAIK, Jun Heum , KIM, Eunjung , HAN, Tae-Young , GERICH, Carola , ZEH, Christoph , HAERTLING, Thomas , OPITZ, Joerg , SCHREIBER, Juergen
IPC分类号： G01N33/52 , G01N21/64 , G01N33/68
CPC分类号： G01N21/6486 , G01N21/6408
摘要： The present invention relates to a prostate cancer diagnosis device including a semiconductor laser emitting a laser beam; an optical unit transmitting the laser beam to a prostate sample and receiving auto-fluorescence generated from the prostate sample; a detection unit detecting the auto-fluorescence received by the optical unit and measuring intensity of a single photon corresponding to a single pulse to detect intensity of the time-dependent auto-fluorescence (hereinafter referred to as an auto-fluorescence measured value); and a diagnosis unit calculating fractal dimension values D F of the auto-fluorescence measured value using a fractal dimension algorithm, and a prostate cancer diagnosis method using the same.
摘要翻译：本发明涉及一种包括发射激光束的半导体激光器的前列腺癌诊断装置，将激光束透射到前列腺样品并接收从前列腺样品产生的自发荧光的光学单元; 检测单元，检测由光学单元接收的自动荧光，并测量与单个脉冲对应的单个光子的强度，以检测时间依赖性自动荧光的强度（以下称为自动荧光测量值）; 以及使用分维数算法计算自动荧光测量值的分形维数DF的诊断单元，以及使用其的前列腺癌诊断方法。

6. 发明申请

WO2011098079A2 SENSING SYSTEM FOR DETERMINING THE FATIGUE ON METAL COMPONENTS 审中-公开
标题翻译：传感器系统确定疲劳的金属部件
公开(公告)号：WO2011098079A2
公开(公告)日：2011-08-18
申请号：PCT/DE2011000154
申请日：2011-02-10
申请人： FRAUNHOFER GES FORSCHUNG , ZASIMCHUCK ELENA , GORDIENKO YURI , SCHREIBER JUERGEN
发明人： ZASIMCHUCK ELENA , GORDIENKO YURI , SCHREIBER JUERGEN
IPC分类号： G01N3/32
CPC分类号： G01N3/32 , G01L1/00 , G01M5/0033 , G01M5/0083 , G01M5/0091 , G01N2203/0073 , G01N2203/0623 , G01N2203/0629
摘要： The invention relates to a sensing system for determining the fatigue on metal components. The aim of the invention is to provide a sensing system for non-destructively determining the fatigue on metal components, said system being usable in a flexible manner. The sensing system according to the invention is fixed to a component by means of a multilayer structure. A first layer formed from monocrystalline metal is directly bonded over the entire area of a surface of the component. A second electrically insulating polymer layer and a third layer which is sensitive or which contains sensing elements are applied on said first layer.
摘要翻译：本发明涉及一种传感器系统，用于确定金属部件的疲劳。本发明的目的是提供用于非破坏性地确定金属组分的可用的疲劳，这是提供灵活的传感器系统。根据本发明的传感器系统安装于组件上的多层结构。形成在整个表面层上的第一单晶金属直接附着材料配合的部件的表面上。在该第一层，第二电绝缘聚合物层和含有敏感或传感器元件的第三层被施加。

7. 发明申请

WO2008080395A2 METHOD FOR DETERMINING THE REMAINING SERVICE LIFE AND/OR FATIGUE STATE OF COMPONENTS 审中-公开
标题翻译：方法用于确定组件的剩余寿命和/或处于疲劳状态
公开(公告)号：WO2008080395A2
公开(公告)日：2008-07-10
申请号：PCT/DE2008000020
申请日：2008-01-02
申请人： FRAUNHOFER GES FORSCHUNG , SCHREIBER JUERGEN , KROENING MICHAEL , PANIN VIKTOR JEFGENEVITSCH
发明人： SCHREIBER JUERGEN , KROENING MICHAEL , PANIN VIKTOR JEFGENEVITSCH
CPC分类号： G01N3/32 , G01N27/72 , G01N27/9046 , G01N2203/0073 , G01N2203/0218
摘要： The invention relates to a method for determining the remaining service life and/or fatigue state of components. The object of the invention is to propose a possibility by means of which the fatigue state and/or the remaining service life of components made of pliable metallic materials can be non-destructively determined without having knowledge of any of the stresses or previous damage already having affected the respective component. In order to determine the remaining service life and/or the fatigue state of components made of pliable metallic or brittle material, the procedure is such that stress amplitudes are determined on the component in a locally defined manner within characteristic time intervals ?ti with load cycles per time interval a(?t i ) = ?N (?t i ) /?t i associated therewith in a time-referenced manner. For this purpose, the load cycles NB (?t i ) representative of the determined stress amplitudes until the breaking point has been reached are ascertained from the Wöhler curve of the respective material, the fractal dimension DF (m) is determined from the measured electric or magnetic noise signals for larger time intervals ?T m = ? ?t i, and the remaining service life, or the fatigue state, is determined from the same.
摘要翻译：本发明涉及一种用于确定剩余使用寿命和/或部件的疲劳状态的方法。本发明的目的是提出一种可能性，用以确定所述疲劳状况和/或由塑性可变形的金属材料非破坏性地，不需事先已知的部件已经针织负载或以前损伤部件的剩余使用寿命。为了确定由可塑性变形的金属或脆性材料的剩余寿命和/或部件的疲劳状态下，该过程是这样的一个局部在组件电压振幅的特性的时间间隔内限定≤T_{I 与它们相关的周期数每时间间隔（？吨_{I ）= N（T _{I ）/ΔT_{I 是相对于时间来决定。从特定材料的SN曲线，所确定的电压振幅的负载循环Ñ_{乙（T _{I ）代表由此确定直到从用于测量的电或磁噪声信号在到达突破点更大的时间间隔≤T_{米 =？ ≤T_{I 分形维数D _{˚F（M）确定，并且计算剩余寿命或疲劳状况。}}}}}}}}}

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