专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO1996004254A3 BENZODIAZEPINE DERIVATIVES 审中-公开
公开(公告)号：WO1996004254A3
公开(公告)日：1996-02-15
申请号：PCT/JP1995001497
申请日：1995-07-27
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , NIPPON SHOKUBAI CO., LTD. , SATO, Yoshinari , SAKANE, Kazuo , TABUCHI, Seiichiro , MITSUI, Hitoshi , KATSUMI, Ikuyo , SATOH, Yuichi
发明人： FUJISAWA PHARMACEUTICAL CO., LTD. , NIPPON SHOKUBAI CO., LTD.
IPC分类号： C07D243/14

2. 发明申请

WO9604254A2 BENZODIAZEPINE DERIVATIVES 审中-公开
标题翻译：苯并咪唑衍生物
公开(公告)号：WO9604254A2
公开(公告)日：1996-02-15
申请号：PCT/JP9501497
申请日：1995-07-27
申请人： FUJISAWA PHARMACEUTICAL CO , NIPPON CATALYTIC CHEM IND , SATO YOSHINARI , SAKANE KAZUO , TABUCHI SEIICHIRO , MITSUI HITOSHI , KATSUMI IKUYO , SATOH YUICHI
发明人： SATO YOSHINARI , SAKANE KAZUO , TABUCHI SEIICHIRO , MITSUI HITOSHI , KATSUMI IKUYO , SATOH YUICHI
IPC分类号： C07D243/14 , A61K31/55 , A61K31/551 , A61P1/00 , A61P25/04 , A61P25/18 , C07D243/24 , C07D243/26 , C07D401/06 , C07D403/06 , C07D405/06 , C07D409/06 , C07D413/06 , C07D417/06 , C07D487/08 , C07D401/12 , C07D403/12 , C07D403/14 , C07D407/12 , C07D407/14 , C07D409/12 , C07D413/12 , C07D417/14 , C07F5/02
CPC分类号： C07D243/24
摘要： Benzodiazepine derivatives of formula (I) wherein R is aryl which may have one or more suitable substituent(s), R is C3-C8 cycloalkyl which may have one or more suitable substituent(s), A is lower alkylene, R is a heterocyclic group selected from the group consisting of tetrahydrofuryl, dioxolanyl, furyl, thienyl, isoxazolyl, pyridyl, benzimidazolyl, benzothiazolyl, benzoxazolyl, benzopyranyl, quinolyl, isoquinolyl, tetrahydroisoquinolyl, benzothienyl and benzofuryl, each of which may have one or more suitable substituent(s), or a pharmaceutically acceptable salt thereof, which are useful as a medicament.
摘要翻译：式（I）的苯并二氮杂衍生物，其中R 1为可具有一个或多个合适取代基的芳基，R 2为可具有一个或多个合适取代基的C 3 -C 8环烷基，A较低亚烷基，R 3是选自四氢呋喃基，二氧戊环基，呋喃基，噻吩基，异恶唑基，吡啶基，苯并咪唑基，苯并噻唑基，苯并恶唑基，苯并吡喃基，喹啉基，异喹啉基，四氢异喹啉基，苯并噻吩基和苯并呋喃基的杂环基。具有一种或多种可用作药物的合适的取代基或其药学上可接受的盐。

3. 发明申请

WO1994011375A1 TRICYCLIC COMPOUND 审中-公开
标题翻译：三聚体化合物
公开(公告)号：WO1994011375A1
公开(公告)日：1994-05-26
申请号：PCT/JP1993001601
申请日：1993-11-04
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , SATO, Yoshinari , ITANI, Hiromichi
发明人： FUJISAWA PHARMACEUTICAL CO., LTD.
IPC分类号： C07D487/06
CPC分类号： C07D487/06
摘要： A tricyclic compound useful as a medicine, represented by general formula (I), a pharmaceutically acceptable salt thereof, an intermediate therefor, a process for producing the same, and a cholecystokinin antagonist, wherein R represents hydrogen, carboxyl, protected carboxyl, carboxy(lower)alkyl, protected carboxy(lower)alkyl, carboxy(lower)alkanoyl, protected carboxy(lower)alkanoyl, carboxy(lower)alkenoyl, protected carboxy(lower)alkenoyl, optionally substitued heterocyclic carbonyl(lower)alkyl, or optionally substituted heterocyclic carbonyl(lower)alkanoyl; R represents optionally substituted aryl; and R represents acyl.
摘要翻译：用作药物的三环化合物，由通式（I）表示，其药学上可接受的盐，其中间体，其制备方法和缩胆囊素拮抗剂，其中R 1表示氢，羧基，被保护的羧基，羧基（低级）烷基，保护的羧基（低级）烷基，羧基（低级）烷酰基，保护的羧基（低级）烷酰基，羧基（低级）烯酰基，被保护的羧基（低级）烯酰基，任选取代的杂环羰基（低级）任选取代的杂环羰基（低级）烷酰基; R 2表示任选取代的芳基; R 3表示酰基。

4. 发明申请

WO1992003438A1 TRICYCLIC BENZODIAZEPINE DERIVATES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开
标题翻译：三氯苯二酮衍生自己的制剂和药物组合物
公开(公告)号：WO1992003438A1
公开(公告)日：1992-03-05
申请号：PCT/JP1991001112
申请日：1991-08-22
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , SATO, Yoshinari , MATUO, Teruaki , OGAHARA, Takatomo
发明人： FUJISAWA PHARMACEUTICAL CO., LTD.
IPC分类号： C07D487/06
CPC分类号： C07D487/06
摘要： Tricyclic compounds of the formula (I) wherein R is hydrogen or an organic group, R is aryl which may have suitable substituent(s), R is hydrogen or an acyl group and A is lower alkylene, and pharmaceutically acceptable salts thereof which are useful as a medicament.
摘要翻译：式（I）的三环化合物，其中R 1是氢或有机基团，R 2是可具有合适取代基的芳基，R 3是氢或酰基，A是低级亚烷基及其药学上可接受的盐，其可用作药物。

5. 发明申请

WO2004022540A3 PYRIDAZINONE AND PYRIDONE DERIVATIVES AS ADENOSINE ANTAGONISTS 审中-公开
标题翻译：吡咯烷酮和吡啶酮衍生物作为腺苷拮抗剂
公开(公告)号：WO2004022540A3
公开(公告)日：2004-07-01
申请号：PCT/JP0311271
申请日：2003-09-03
申请人： FUJISAWA PHARMACEUTICAL CO , TABUCHI SEIICHIRO , TSUTSUMI HIDEO , SATO YOSHINARI , AKAHANE ATSUSHI
发明人： TABUCHI SEIICHIRO , TSUTSUMI HIDEO , SATO YOSHINARI , AKAHANE ATSUSHI
IPC分类号： A61P9/10 , A61P25/00 , C07D213/64 , C07D213/73 , C07D401/04 , C07D401/14 , C07D417/14 , A61K31/501
CPC分类号： C07D213/64 , C07D213/73 , C07D401/04 , C07D401/14 , C07D417/14
摘要： A pyridazinone or pyridone compound of the following formula (I). wherein',Itor a salt thereof. The pyridazinone or pyridone compound (I) and a salt thereof of the present invention are adenosine antagonists and are useful for the prevention and/or treatment of depression, dementia (e.g. Alzheimer's disease, cerebrovascular dementia, dementia accompanying Parkinson's disease, etc.), Parkinson's disease, anxiety, pain, cerebrovascular disease (e.g. stroke, etc.), heart failure and the like.
摘要翻译：下式（I）的哒嗪酮或吡啶酮化合物。其中'，它是其盐。本发明的哒嗪酮或吡啶酮化合物（I）及其盐是腺苷拮抗剂，可用于预防和/或治疗抑郁，痴呆（例如阿尔茨海默病，脑血管性痴呆，伴有帕金森病的痴呆等），帕金森病，焦虑症，疼痛，脑血管病（例如中风等），心力衰竭等。

6. 发明申请

WO2004022540A2 PYRIDAZINONE COMPOUND AND PHARMACEUTICAL USE THEREOF 审中-公开
标题翻译：吡咯烷酮化合物及其药物用途
公开(公告)号：WO2004022540A2
公开(公告)日：2004-03-18
申请号：PCT/JP2003/011271
申请日：2003-09-03
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , TABUCHI, Seiichiro , TSUTSUMI, Hideo , SATO, Yoshinari , AKAHANE, Atsushi
发明人： TABUCHI, Seiichiro , TSUTSUMI, Hideo , SATO, Yoshinari , AKAHANE, Atsushi
IPC分类号： C07D213/73
CPC分类号： C07D213/64 , C07D213/73 , C07D401/04 , C07D401/14 , C07D417/14
摘要： A pyridazinone or pyridone compound of the following formula (I). wherein',Itor a salt thereof. The pyridazinone or pyridone compound (I) and a salt thereof of the present invention are adenosine antagonists and are useful for the prevention and/or treatment of depression, dementia (e.g. Alzheimer's disease, cerebrovascular dementia, dementia accompanying Parkinson's disease, etc.), Parkinson's disease, anxiety, pain, cerebrovascular disease (e.g. stroke, etc.), heart failure and the like.
摘要翻译：下式（I）的哒嗪酮或吡啶酮化合物。其中'，它或其盐。本发明的哒嗪酮或吡啶酮化合物（I）及其盐是腺苷拮抗剂，可用于预防和/或治疗抑郁，痴呆（例如阿尔茨海默病，脑血管性痴呆，伴有帕金森病的痴呆等），帕金森病，焦虑症，疼痛，脑血管疾病（例如中风等），心力衰竭等。

7. 发明申请

WO2004089939A1 CONDENSED FURAN DERIVATIVES AS ADENOSINE ANTAGONISTS 审中-公开
标题翻译：浓缩的呋喃衍生物作为腺苷拮抗剂
公开(公告)号：WO2004089939A1
公开(公告)日：2004-10-21
申请号：PCT/JP2004/003435
申请日：2004-03-15
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , YONISHI, Satoshi , ITANI, Hiromichi , SATO, Yoshinari , TSUTSUMI, Hideo , AKAHANE, Atsushi
发明人： YONISHI, Satoshi , ITANI, Hiromichi , SATO, Yoshinari , TSUTSUMI, Hideo , AKAHANE, Atsushi
IPC分类号： C07D405/04
CPC分类号： C07D491/04 , C07D405/04
摘要： A novel compound of the following formula (I): wherein Z is a phenyl or pyridyl which condenses to a furan ring; X is CH or N; R 1 is hydrogen or optionally substituted lower alkyl; R 2 is hydrogen, halogen or lower alkoxy; and R 3 is hydrogen, hydroxy, lower alkyl, lower alkoxy or halogen, or a salt thereof. The compound (I) and salt thereof of the present invention are adenosine antagonists and are useful for the prevention and/or treatment of depression, dementia (e.g. Alzheimer's disease, cerebrovascular dementia, dementia accompanying Parkinson's disease, etc.), Parkinson's disease, anxiety, pain, cerebrovascular disease (e.g. stroke, etc.), heart failure and the like.
摘要翻译：下式（I）的新化合物：其中Z是与呋喃环稠合的苯基或吡啶基; X是CH或N; R 1是氢或任选取代的低级烷基; R 2是氢，卤素或低级烷氧基; 和R 3是氢，羟基，低级烷基，低级烷氧基或卤素，或其盐。本发明的化合物（I）及其盐是腺苷拮抗剂，可用于预防和/或治疗抑郁，痴呆（例如阿尔茨海默病，脑血管性痴呆，伴随帕金森病的痴呆等），帕金森病，焦虑症，疼痛，脑血管疾病（例如中风等），心力衰竭等。

8. 发明申请

WO1998015535A1 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS 审中-公开
标题翻译： 1,4-苯并恶嗪酮及其作为CCK拮抗剂的用途
公开(公告)号：WO1998015535A1
公开(公告)日：1998-04-16
申请号：PCT/JP1997003483
申请日：1997-09-29
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , NIPPON SHOKUBAI CO., LTD. , SATO, Yoshinari , TABUCHI, Seiichiro , MITSUI, Hitoshi , KATSUMI, Ikuyo , YAMAMOTO, Naoko
发明人： FUJISAWA PHARMACEUTICAL CO., LTD. , NIPPON SHOKUBAI CO., LTD.
IPC分类号： C07D243/14
CPC分类号： C07K5/0821 , A61K38/00 , C07D243/14 , C07D243/18 , C07K5/0205 , C07K5/06139
摘要： Benzodiazepine derivatives of formula (I) wherein R is alkyl or cycloalkyl-alkyl when R is hydrogen, or R is a variety of specified groups when R is alkyl, halogen or dialkylamino, are useful as cholecystokinin antagonists.
摘要翻译：当R 4为氢时R 2为烷基或环烷基 - 烷基的式（I）的苯并二氮杂衍生物，或当R 4为烷基，卤素或二烷基氨基时，R 2为多种规定基团作为缩胆囊素拮抗剂有用。

9. 发明申请

WO1992001683A1 BENZODIAZEPINE DERIVATIVES 审中-公开
标题翻译：苯并咪唑衍生物
公开(公告)号：WO1992001683A1
公开(公告)日：1992-02-06
申请号：PCT/JP1991000952
申请日：1991-07-17
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , SATO, Yoshinari , ITANI, Hiromichi , OGAHARA, Takatomo
发明人： FUJISAWA PHARMACEUTICAL CO., LTD.
IPC分类号： C07D403/06
CPC分类号： C07D401/14 , C07D243/24 , C07D403/06 , C07D403/14
摘要： Benzodiazepine derivatives of formula (I), wherein R is heterocyclic group which may have one or more suitable substituent(s), or cyano, R is hydrogen or halogen, R is aryl which may have one or more suitable substituent(s), R is aryl which may have one or more suitable substituent(s), etc., and A is lower alkylene, and pharmaceutically acceptable salts thereof which are useful as a medicament.
摘要翻译：式（I）的苯并二氮杂衍生物，其中R 1是可以具有一个或多个合适的取代基的杂环基或氰基，R 2是氢或卤素，R 3是可以具有一个或更合适的取代基，R 4是可以具有一个或多个合适的取代基等的芳基，A是可用作药物的低级亚烷基及其药学上可接受的盐。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式