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1. 发明申请

WO1995004711A1 PROCESS FOR PRODUCING D-CHIRO-INOSITOL 审中-公开
标题翻译：生产D-CHIRO-INOSITOL的方法
公开(公告)号：WO1995004711A1
公开(公告)日：1995-02-16
申请号：PCT/JP1994001304
申请日：1994-08-08
申请人： HOKKO CHEMICAL INDUSTRY CO., LTD. , ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI , SATO, Kiyoshi , YOSHIDA, Makoto , KANBE, Kenji , HIRAZAWA, Kiyoshi , TAKEUCHI, Tomio
发明人： HOKKO CHEMICAL INDUSTRY CO., LTD. , ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI
IPC分类号： C07C35/16
CPC分类号： C07C35/16 , C07B2200/07 , C07C29/10 , C07C2601/14
摘要： A process for producing D-chiro-inositol which comprises either mixing an aqueous solution of kasugamycin or a salt thereof with a strongly acidic ion-exchange resin (of H type) in a reactor or bringing the aqueous solution into contact with the resin in a column packed therewith, heating the aqueous solution and the resin under normal or applied pressure to effect hydrolysis of kasugamycin to thereby prepare an acidic reaction solution containing D-chiro-inositol, separating the acidic reaction solution from the resin, and recovering D-chiro-inositol from the solution. In this stage, it is possible to obtain efficiently high-purity D-chiro-inositol by passing the acidic reaction solution first through a column packed with a strongly acidic ion-exchange resin (of H type) and then through another column packed with a strongly basic ion-exchange resin (of OH type) to prepare a neutral eluate containing D-chiro-inositol, and concentrating the eluate to effect deposition of D-chiro-inositol crystals.
摘要翻译：一种生产D-手性肌醇的方法，其包括在反应器中混合春日霉素或其盐与强酸性离子交换树脂（H +型）的水溶液或使水溶液与树脂在正常或施加压力下加热水溶液和树脂，以实现春雷霉素的水解，从而制备含有D-手性肌醇的酸性反应溶液，将酸性反应溶液与树脂分离，并回收D - 肌醇溶液。在这个阶段，通过使酸性反应溶液首先通过填充有强酸性离子交换树脂（H +型）的柱然后通过另一个柱子，可以有效地获得高纯度D-手性肌醇填充强碱性离子交换树脂（OH型）以制备含有D-手性肌醇的中性洗脱液，并浓缩洗脱液以实现D-手性肌醇晶体的沉积。

2. 发明申请

WO1996010405A1 ANTITUMOR AGENT 审中-公开
标题翻译：抗菌剂
公开(公告)号：WO1996010405A1
公开(公告)日：1996-04-11
申请号：PCT/JP1995001893
申请日：1995-09-20
申请人： KYOWA HAKKO KOGYO CO., LTD. , SAITO, Hiromitsu , AMISHIRO, Nobuyoshi , NAGAMURA, Satoru , KOBAYASHI, Eiji , OKAMOTO, Akihiko , GOMI Katsushige , YAMASHITA, Kinya , SATO, Kiyoshi , NAKAKURA, Masashi , HAYAKAWA, Eiji
发明人： KYOWA HAKKO KOGYO CO., LTD.
IPC分类号： A61K31/40
CPC分类号： C07D487/04 , C07D487/10
摘要： An antitumor agent against drug-fast tumors containing a compound represented by general formula (2) or (a) or a pharmacologically acceptable salt thereof as the active ingredient; wherein X represents Cl or Br; and R represents NR R (wherein R and R represent each independently hydrogen or C1-C4 linear or branched alkyl) or a group of formula (b) (wherein R represents CH2 or N-CH3). The agent has an excellent antitumor activity against drug-insensitive tumors and is useful as an antitumor agent against drug-fast tumors.
摘要翻译：一种含有通式（2）或（a）所示化合物或其药理学上可接受的盐作为有效成分的药物抗肿瘤药物的抗肿瘤剂; 其中X表示Cl或Br; 和R表示NR 1 R 2（其中R 1和R 2各自独立地表示氢或C 1 -C 4直链或支链烷基）或式（b）的基团（其中R 3表示 CH2或N-CH3）。该药剂对药物不敏感的肿瘤具有优异的抗肿瘤活性，可用作抗药物肿瘤的抗肿瘤剂。

3. 发明申请

WO1990007510A1 POLYETHER ANTIBIOTIC MI215-NF3, PRODUCTION THEREOF, AND DRUG FOR TREATING FOWL COCCIDIOSIS 审中-公开
标题翻译：聚醚抗生素MI215-NF3，其生产方法及用于治疗肝癌的药物
公开(公告)号：WO1990007510A1
公开(公告)日：1990-07-12
申请号：PCT/JP1989001328
申请日：1989-12-28
申请人： HOKKO CHEMICAL INDUSTRY CO., LTD. , ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI , TAKEUCHI, Tomio , TAKAHASHI, Yoshikazu , HAMADA, Masa , NAGANAWA, Hiroshi , SATO, Kiyoshi
发明人： HOKKO CHEMICAL INDUSTRY CO., LTD. , ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI
IPC分类号： C07D493/10
CPC分类号： C07D493/10 , C12P17/181
摘要： This invention relates to a new polyether antibiotic MI215-NF3 of formula (I) and salts thereof. These compounds are actinomycetes obtained from the culture of Actinomadura sp. MI215-NF3, a new strain belonging to the genus Actinomadura. They are used effectively for the treatment of fowl coccidiosis and also have a useful antibacterial activity against certain bacteria.

4. 发明申请

WO1994012448A1 PROCESS FOR PRODUCING CERAMIC PRODUCT 审中-公开
标题翻译：生产陶瓷制品的工艺
公开(公告)号：WO1994012448A1
公开(公告)日：1994-06-09
申请号：PCT/JP1993001730
申请日：1993-11-26
申请人： TONEN CORPORATION , KAYA, Hiroshi; , SATO, Kiyoshi; , MOROZUMI, Hiroki; , TEZUKA, Atsushi; , AOKI, Tomoko; , NAKAHARA, Hirohiko; , SUZUKI, Tadashi; , ISODA, Takeshi;
发明人： TONEN CORPORATION
IPC分类号： C04B35/58
CPC分类号： C04B41/009 , C04B35/589 , C04B35/80 , C04B35/806 , C04B41/4554 , C04B41/5053 , C04B41/52 , C04B41/81 , C04B41/87 , C04B41/89 , C04B41/4531 , C04B41/524 , C04B35/00 , C04B35/58 , C04B38/00
摘要： A ceramic product is produced by mixing a preform of metallic or ceramic fibers or a porous ceramic with at least one polysilazane (1) having a number-average molecular weight of 20 to 3,000 and a cold viscosity of less than 1 Pa.s and selected from among a polysilazane mainly comprising repeating units of the formula -[(SiH2)n(NH)r]- (wherein n and r are each 1, 2 or 3) and derivatives based thereon, such as copolymers, modified polymers and cross-linked polymers, and at least one polysilazane (2) selected from among ones having a number-average molecular weight of 200 to 100,000 and a cold viscosity of 100 Pa.s or above and solid ones, impregnating the mixture with a polysilazane-base polymer mixture having a number-average molecular weight of 200 to 3,000 and a cold viscosity of 100 Pa.s or less, hardening the resulting mixture by cross-linking, firing the same into a ceramic, and repeating these operations. Examples of the polysilazanes include inorganic polysilazane, inorganic polysiloxazane, polyorgano(hydro)silazane, modified polysilazane and polymetallosilazane. It is possible to inhibit the delamination of the fibers by applying CVD coating before or after the impregnation, hardening and firing of the preform.
摘要翻译：通过将金属或陶瓷纤维或多孔陶瓷的预制件与至少一种数均分子量为20至3,000并且冷粘度小于1Pa.s的聚硅氮烷（1）混合制备陶瓷产品，并选择来自主要包含式 - [（SiH 2）n（NH）r] - （其中n和r各自为1,2或3）的重复单元的聚硅氮烷及其衍生物，例如共聚物，改性聚合物和交联剂，连接的聚合物和至少一种选自数均分子量为200〜100,000，冷粘度为100Pa·s以上的聚硅氮烷（2）和固体聚合物，将聚硅氮烷基聚合物数均分子量为200〜3000，冷粘度为100Pa·s以下的混合物，通过交联硬化所得到的混合物，将其烧成陶瓷，并重复这些操作。聚硅氮烷的实例包括无机聚硅氮烷，无机聚硅氮烷，聚有机（水）硅氮烷，改性聚硅氮烷和聚金属硅氮烷。通过在预成型体的浸渍，硬化和烧制之前或之后施加CVD涂层可以抑制纤维的分层。

5. 发明申请

WO1988009612A1 METHOD OF PRODUCING HERBICIDE-RESISTANT RICE PLANT, SAID RICE PLANT AND SEED OF SAID RICE PLANT 审中-公开
标题翻译：生产抗除草剂植物的方法，种子植物和种子植物
公开(公告)号：WO1988009612A1
公开(公告)日：1988-12-15
申请号：PCT/JP1988000534
申请日：1988-05-31
申请人： HOKKO CHEMICAL INDUSTRY CO., LTD. , TERAKAWA, Teruhiko , SATO, Kiyoshi
发明人： HOKKO CHEMICAL INDUSTRY CO., LTD.
IPC分类号： A01H01/00
CPC分类号： A01H4/00 , A01H1/02 , A01H5/10
摘要： This invention relates to a method of producing a herbicide-resistant rice plant which comprises cultivating a callus comprising a cultured cell de dedifferentiated from a tissue of a rice plant in a plant tissue culture medium containing a herbicide added thereto, selecting and taking out a mutant of the callus having herbicide resistance proliferated in the medium containing the herbicide, transferring the mutant to a redifferentiation medium to redifferentiate into a young rice plant, cultivating the redifferentiated young rice plant, and selecting and collecting a plurality of herbicide-resistant seeds from the fructified rice plant. This invention also provides a herbicide-resistant rice plant or a seed of the same.

6. 发明申请

WO1991007261A1 DRYING METHOD FOR WOOD OR THE LIKE 审中-公开
标题翻译：用于木材或类似物的干燥方法
公开(公告)号：WO1991007261A1
公开(公告)日：1991-05-30
申请号：PCT/JP1990001473
申请日：1990-11-13
申请人： MIYAGIKEN , KYOGYOKUMIAI SENDAI FANICHIA , TAKAHASHI, Hideaki , TAMAKAWA, Kinji , SATO, Kiyoshi , SUZUKI, Isao , YUNOME, Satoshi , HONMA, Katsumi , SUZUKI, Yasuo
发明人： MIYAGIKEN , KYOGYOKUMIAI SENDAI FANICHIA
IPC分类号： B27K03/34
CPC分类号： B27K3/34 , B27K5/001 , B27K5/04 , F26B21/06
摘要： This invention relates to a drying method for wood and the like which comprises conducting impregnation treatment by allowing a plant manufactured lumber to be impregnated with an organic impregnant and subjected to a hydrothermal reaction (hydrolysis), fitting an acoustic emission sensor to the lumber or the like thus subjected to the impregnation treatment, detecting an acoustic emission which the lumber or the like generates with the change of their wood structure as a signal, forecasting cracks in the lumber or the like by data-processing the signal and carrying out heat treatment while controlling the atmosphere using temperature and humidity as operation factors on the basis of the forecast data so that no cracks occur in the lumber or the like. The present invention relates also to a drying method of lumber or the like which is characterized in that heating and drying are carried out after the lumber or the like is impregnation treated with an organic impregnant.
摘要翻译：本发明涉及一种用于木材等的干燥方法，其包括通过使植物制造的木材浸渍有机浸渍剂进行浸渍处理并进行水热反应（水解），将声发射传感器装配到木材或像这样进行浸渍处理，通过木材结构的变化作为信号，检测木材等产生的声发射，通过数据处理信号并进行热处理来预测木材等中的裂纹，同时基于预测数据，使用温度和湿度控制气氛作为操作因素，使得在木材等中不发生裂纹。本发明还涉及木材等的干燥方法，其特征在于在用有机浸渍剂浸渍处理木材等之后进行加热和干燥。

7. 发明申请

WO1991005643A1 METHOD OF MODIFYING TREATMENT OF TIMBER AND THE LIKE 审中-公开
标题翻译：修改木材处理方法等
公开(公告)号：WO1991005643A1
公开(公告)日：1991-05-02
申请号：PCT/JP1990001332
申请日：1990-10-16
申请人： MIYAGIKEN , KYOGYOKUMIAI SENDAI FANICHIA , TAKAHASHI, Hideaki , TAMAKAWA, Kinji , SATO, Kiyoshi , SUZUKI, Isao , YUNOME, Satoshi , HONMA, Katsumi , SUZUKI, Yasuo
发明人： MIYAGIKEN , KYOGYOKUMIAI SENDAI FANICHIA
IPC分类号： B27K05/00
CPC分类号： B27K3/36 , B27K5/04 , F26B21/06
摘要： Confident that, when cracks occur in a piece of timber due to the heat treatment of the timber, an acoustic emission (AE) should occur, an effective AE signal directly involved with the cracks is discriminated and detected, and, in addition to this, the total (integrated) number of events and the rate of occurrences of AE are monitored while the drying treatment process and the high temperature treatment process are discriminated to thereby put all above evidences together to predict cracks occurring during the processes of the drying treatment and the high temperature treatment, whereby the temperature and humidity are controlled on the basis of the predicted information to thereby control the atmosphere such that the cracks will not occur. Furthermore, in that case, the timber is impregnated with a specific organic solvent medium to conduct the impregnating treatment where the water and the heat react chemically with each other, whereby the interior of the piece of timber is plasticized and the cracks due to the heating treatment are prevented from occurring and the brittleness in the quality of timber due to the high temperature treatment is greatly bettered, thus improving the workability of the timber.

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