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1. 发明申请

WO2006017400A8 BIOPSY DEVICE WITH SELECTABLE TISSUE RECEIVING APERTURE ORIENTATION AND SITE ILLUMINATION 审中-公开
标题翻译：具有选择性组织的生物装置接收孔径方位和场地照明
公开(公告)号：WO2006017400A8
公开(公告)日：2006-10-05
申请号：PCT/US2005027071
申请日：2005-07-29
申请人： SENORX INC , SHABAZ MARTIN V , QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SAFABASH JASON H
发明人： SHABAZ MARTIN V , QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SAFABASH JASON H
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/32 , A61B17/34
CPC分类号： A61B10/0275 , A61B10/0266 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473 , A61B2017/00486 , A61B2017/3405 , A61B2090/3908 , A61B2090/3987
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a patient target site. The device includes a probe component (11) with an elongated tubular section (15), a penetrating distal tip (16) and a tissue receiving aperture (17) in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member (20) which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device has a driver component (12) to which the probe component is releasably secured. The driver has a drive member (22,23) for adjusting the orientation of the tubular section and one or more drive members (30) for moving the tissue cutting member within the tubular section to sever a tissue specimen. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational.
摘要翻译：本发明涉及一种用于从患者靶位置分离和收集组织标本的系统和装置。该装置包括具有细长管状部分（15）的探针部件（11），远侧末端的管状部分的远端中的穿透远端（16）和组织接收孔（17），以及组织切割构件（20），其可滑动地设置在所述探针构件内，以通过对所述组织切割构件的内腔施加真空来切割通过所述孔被拉入所述装置的内部的组织样本。该装置具有驱动器部件（12），探头部件可释放地固定到该部件上。驱动器具有用于调节管状部分的取向的驱动构件（22,23）和用于移动管状部分内的组织切割构件以切断组织样本的一个或多个驱动构件（30）。赋予组织切割器的运动至少是纵向的，并且优选地也是振动和/或旋转。

2. 发明申请

WO2007019445A1 BIOPSY DEVICE WITH FLUID DELIVERY TO TISSUE SPECIMENS 审中-公开
标题翻译：具有流体输送到组织样本的生物装置
公开(公告)号：WO2007019445A1
公开(公告)日：2007-02-15
申请号：PCT/US2006/030722
申请日：2006-08-04
申请人： SENORX, INC. , QUICK, Richard, L. , SHABAZ, Martin, V. , LOUW, Frank, R. , LUBOCK, Paul , SAFABASH, Jason, H.
发明人： QUICK, Richard, L. , SHABAZ, Martin, V. , LOUW, Frank, R. , LUBOCK, Paul , SAFABASH, Jason, H.
IPC分类号： A61B10/02 , A61B17/32 , A61B17/00
CPC分类号： A61B17/32002 , A61B10/0275 , A61B10/0283 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473
摘要： The invention is directed to a system and method for separating and collecting one or more tissue specimens from a target site within a patient and flushing the specimen to remove blood, debris and the like before the specimen is removed from the biopsy device. The flow of flushing fluid to the tissue collector is preferably controlled to coincide with delivery of one or more specimens to the collecting tray or basket of the device or after the receipt of the specimen within the tissue collector to ensure that the fluid (16) is applied to a fresh specimen. The tissue tray or basket within the tissue collector (14) has an open or foraminous portion to facilitate removal of fluid, such as the applied fluid and blood, and other debris from the tissue specimens on the tray. Vacuum (22) is provided within the tissue collector, preferably under the tray to remove fluid and debris from the collector interior.
摘要翻译：本发明涉及一种用于从患者内的目标部位分离和收集一个或多个组织样本的系统和方法，并且在从活检装置移除样本之前冲洗样本以除去血液，碎屑等。冲洗流体到组织收集器的流动优选地被控制以与一个或多个样本递送到装置的收集盘或篮子之间或在组织收集器中收到样本之后确保流体（16）是应用于新鲜的标本。组织收集器（14）内的纸巾托盘或篮子具有开放或有孔的部分，以有助于从托盘上的组织标本中去除流体，例如施加的流体和血液以及其它碎屑。真空（22）设置在组织收集器内，优选在托盘下面，以从收集器内部去除流体和碎屑。

3. 发明申请

WO2010047984A1 MICRO-VITREORETINAL TROCAR BLADE 审中-公开
标题翻译： MICRO-VITREORETINAL TROCAR刀片
公开(公告)号：WO2010047984A1
公开(公告)日：2010-04-29
申请号：PCT/US2009/060307
申请日：2009-10-12
申请人： ALCON RESEARCH, LTD. , AUCHTER, Gregory, A. , AULD, Jack, R. , BERARDI, Randal, L. , FALLER, Harry, Edward , HICKINGBOTHAM, Dyson, W. , MCCOLLAM, Christopher, L. , SAFABASH, Jason, H. , SAUER, Willard, L.
发明人： AUCHTER, Gregory, A. , AULD, Jack, R. , BERARDI, Randal, L. , FALLER, Harry, Edward , HICKINGBOTHAM, Dyson, W. , MCCOLLAM, Christopher, L. , SAFABASH, Jason, H. , SAUER, Willard, L.
IPC分类号： A61B17/34 , A61F9/007
CPC分类号： A61B17/3417 , A61B2017/3454 , A61F9/007
摘要： Embodiments of a micro-vitreoretinal trocar blade (100) may have a top surface and a bottom surface that converge to form cutting edges. Each of the top surface and bottom surface have a large rounded apex to maximize the area of the blade. Each surface also has concave regions that may form the cutting edges. Advancing the MVR trocar blade into tissue causes the tissue to contact the apexes of the top and bottom surfaces. The apexes draw the tissue into contact with the cutting edges. The cutting edges incise the tissue such that the incision is sized to accommodate a trocar cannula. The geometry of the top surface and bottom surface ensure that the features of the blade do not protrude radially outside of the diametral envelope of the shaft (110).
摘要翻译：微玻璃体视网膜套管针叶片（100）的实施例可以具有会聚以形成切割边缘的顶表面和底表面。顶表面和底表面中的每一个具有大的圆形顶点以使刀片的面积最大化。每个表面还具有可形成切割边缘的凹形区域。将MVR套管针刀片推入组织使得组织接触顶表面和底表面的顶点。顶点使组织与切割边缘接触。切割边缘切开组织，使得切口的尺寸适于容纳套管针套管。顶表面和底表面的几何形状确保了叶片的特征不会径向地突出到轴（110）的直径外壳的外侧。

4. 发明申请

WO2014137983A1 AUTOMATED PRELOADED INTRAOCULAR LENS INJECTOR 审中-公开
标题翻译：自动预测的内窥镜镜头注射器
公开(公告)号：WO2014137983A1
公开(公告)日：2014-09-12
申请号：PCT/US2014/020138
申请日：2014-03-04
申请人： ABBOTT MEDICAL OPTICS INC. , SAFABASH, Jason, H.
发明人： SAFABASH, Jason, H.
IPC分类号： A61F2/16
CPC分类号： A61F2/1678 , A61F2/1662 , A61F2/167 , A61F2/1672
摘要： This intraocular lens (lOL) injector for delivering an lOL into an eye of a patient includes an lOL load chamber and connected delivery tube, and a spring-loaded push rod for urging the lOL through the delivery tube and out of a distal tip thereof. The injector includes an actuator (30) that is cocked to compress an automatic delivery coil spring (52). Cocking the actuator also folds the lOL and may elongate a dual optic lOL. A braking (48) mechanism may be provided to permit control of the spring-biased lOL advancement. The injector is in a pen style with finger plates on the side for better ergonomic control.
摘要翻译：用于将lOL输送到患者眼睛中的眼内透镜（lOL）注射器包括：lOL装载室和连接的输送管;以及弹簧加载的推杆，用于通过输送管推出lOL并从其远端顶端。喷射器包括致动器（30），其被压缩以压缩自动输送螺旋弹簧（52）。使致动器旋转也可以折叠LOL并且可以延长双光学元件。可以提供制动（48）机构以允许控制弹簧偏置的LOL前进。注射器是笔式，侧面有指板，用于更好的人体工程学控制。

5. 发明申请

WO2014137925A1 ATRAUMATIC IOL INSERTION CARTRIDGE OPENING 审中-公开
标题翻译： ATRAUMATIC IOL插入盒开放
公开(公告)号：WO2014137925A1
公开(公告)日：2014-09-12
申请号：PCT/US2014/019987
申请日：2014-03-03
申请人： ABBOTT MEDICAL OPTICS INC. , SAFABASH, Jason, H. , GAYLORD, David, W. , SPRINGER, Kevin, R.
发明人： SAFABASH, Jason, H. , GAYLORD, David, W. , SPRINGER, Kevin, R.
IPC分类号： A61F2/16
CPC分类号： A61F2/1678
摘要： This intraocular lens (IOL) injector cartridge has a proximal opening in a main body for receiving an IOL. The main body has a lumen that extends longitudinally to a distal end having an opening smaller than the IOL. Passage through the lumen compresses or rolls the IOL so that when the distal end is inserted through a small incision in the eye the IOL can be expelled into the capsular bag. The distal end of the cartridge is beveled with a leading tip in front of a trailing heel. The characteristics of the beveled end are such that damage to the IOL is reduced. The bevel may be straight or curved and includes a distal face defined by the thickness of the distal end between the lumen and an exterior surface. The distal face may be flush with the bevel or chamfered. An inner corner angle between the distal face and the lumen is ≥ 60° to reduce the chance of scratching the IOL as it passes out of the distal opening.
摘要翻译：该眼内透镜（IOL）注射器盒具有用于接收IOL的主体中的近端开口。主体具有纵向延伸到具有小于IOL的开口的远端的内腔。通过腔的通过压缩或滚动IOL，使得当远端通过眼睛中的小切口插入时，IOL可以被排出到囊袋中。墨盒的远端在后跟的前方具有前端尖端。倾斜端的特征使得减少对IOL的损伤。斜面可以是直的或弯曲的，并且包括由内腔和外表面之间的远端的厚度限定的远侧面。远侧面可以与斜面或倒角齐平。远端面和内腔之间的内角角度≥60°，以减少IOL从远端开口处刮伤的可能性。

6. 发明申请

WO2006017400A3 BIOPSY DEVICE WITH SELECTABLE TISSUE RECEIVING APERTURE ORIENTATION AND SITE ILLUMINATION 审中-公开
标题翻译：具有选择性组织的生物装置接收孔径方位和场地照明
公开(公告)号：WO2006017400A3
公开(公告)日：2006-05-18
申请号：PCT/US2005027071
申请日：2005-07-29
申请人： SENORX INC , SHABAZ MARTIN V , QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SAFABASH JASON H
发明人： SHABAZ MARTIN V , QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SAFABASH JASON H
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/32 , A61B17/34
CPC分类号： A61B10/0275 , A61B10/0266 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473 , A61B2017/00486 , A61B2017/3405 , A61B2090/3908 , A61B2090/3987
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component (11) with an elongated tubular section (15), a penetrating distal tip (16) and a tissue receiving aperture (17) in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member (20) which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component (12) to which the probe component is releasably secured. The driver has a drive member (22,23) for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members (30) for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.
摘要翻译：本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。该装置包括具有细长管状部分（15）的探针部件（11），远侧末端的管状部分的远端中的穿透远侧末端（16）和组织接收孔（17），以及组织切割构件（20），其可滑动地设置在所述探针构件内，以通过对所述组织切割构件的内腔施加真空来切割通过所述孔被拉入所述装置的内部的组织样本。该装置还具有驱动器部件（12），探针部件可释放地固定到该部件上。驱动器具有用于调节管状部分的取向并因此调节其中的孔的驱动构件（22,23）和一个或多个驱动构件（30），用于移动管状区段内的组织切割构件以从组织切断组织样本通过孔延伸到管状部分的内部。赋予组织切割器的运动至少是纵向的，并且优选地也是振动和/或旋转以有效地将组织样本与延伸穿过管状部分中的孔的组织分离。

7. 发明申请

WO2006017400A2 BIOPSY DEVICE WITH SELECTABLE TISSUE RECEIVING APERTURE ORIENTATION AND SITE ILLUMINATION 审中-公开
标题翻译：具有选择性组织的生物装置接收孔径方位和场地照明
公开(公告)号：WO2006017400A2
公开(公告)日：2006-02-16
申请号：PCT/US2005/027071
申请日：2005-07-29
申请人： SENORX, INC. , SHABAZ, Martin, V. , QUICK, Richard, L. , LOUW, Frank, R. , LUBOCK, Paul , SAFABASH, Jason, H.
发明人： SHABAZ, Martin, V. , QUICK, Richard, L. , LOUW, Frank, R. , LUBOCK, Paul , SAFABASH, Jason, H.
IPC分类号： A61B10/00
CPC分类号： A61B10/0275 , A61B10/0266 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473 , A61B2017/00486 , A61B2017/3405 , A61B2090/3908 , A61B2090/3987
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured. The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.
摘要翻译：本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。该装置包括具有细长管状部分的探针部件，穿透远侧末端和在远端顶端的管状部分的远端中的组织接收孔，以及组织切割构件，其可滑动地设置在探针构件内以切割组织样本通过向组织切割构件的内腔施加真空而通过孔被拉入装置的内部。该装置还具有驱动器部件，探针组件可释放地固定到该部件上。驱动器具有用于调节管状部分的方向并因此调节其中的孔的驱动构件和一个或多个驱动构件，用于移动管状区段内的组织切割构件以将组织样本从延伸到管状部分内部的组织切断通过光圈。赋予组织切割器的运动至少是纵向的，并且优选地也是振动和/或旋转以有效地将组织样本与延伸穿过管状部分中的孔的组织分离。

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