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    • 2. 发明申请
    • AUTOMATIC CHEMICAL ASSAY CLASSIFICATION
    • 自动化学测试分类
    • WO2011061568A1
    • 2011-05-26
    • PCT/IB2009/055277
    • 2009-11-22
    • AZURE VAULT LTD.RUSSAK, Ze'ev
    • RUSSAK, Ze'ev
    • G01N21/00
    • G06F19/707
    • A computer implemented method for automatic chemical assay classification, the method comprising steps the computer is programmed to perform, the steps comprising: receiving a plurality of sets of parameters, each one of the received sets of parameters characterizing a respective assay of a chemical reaction, calculating a space enhancing proximity among points representative of assays of qualitatively identical chemical reactions, and representing each one of at least two of the received sets of parameters as a respective point in the calculated space, and dividing the points in the calculated space into a number of groups, according to proximity among the points in the calculated space, each group pertaining to a respective chemical reaction, thereby classifying the assays.
    • 一种用于自动化学测定分类的计算机实现方法,所述方法包括计算机被编程为执行的步骤,所述步骤包括:接收多组参数,所接收的参数组中的每一个表征化学反应的相应测定, 计算代表定性相同化学反应测定的点之间的邻近度的空间,并将所接收的参数组中的至少两个中的每一个表示为所计算的空间中的相应点,并将计算出的空间中的点划分为数 的组,根据计算空间中的点之间的接近度,各组属于相应的化学反应,从而对测定进行分类。
    • 3. 发明申请
    • IDENTIFYING TRANSITION POINTS IN CHEMICAL REACTIONS
    • 识别化学反应中的过渡点
    • WO2011030186A1
    • 2011-03-17
    • PCT/IB2009/053997
    • 2009-09-12
    • AZURE VAULT LTD.RUSSAK, Ze'ev
    • RUSSAK, Ze'ev
    • G01N33/48
    • C12Q1/6851G06F19/702G06F19/707C12Q2537/165
    • An apparatus for identifying transition points in a chemical reaction, the apparatus comprising: a property value receiver, configured to receive a plurality of values of a physical property of the chemical reaction, a linear function calculator, associated with the property value receiver, configured to calculate a linear function connecting two of the received values, the two values pertaining to a start and end of a time period, a difference calculator, associated with the linear function calculator, configured to calculate a difference between the linear function and a plurality of the received values pertaining to the time period, and a transition point identifier, associated with the difference calculator, configured to identify at least one transition point of the chemical reaction, using the calculated difference.
    • 一种用于识别化学反应中的转变点的装置,所述装置包括:属性值接收器,被配置为接收所述化学反应的物理性质的多个值,与所述属性值接收器相关联的线性函数计算器,被配置为 计算连接两个接收值的线性函数,与时间段的开始和结束有关的两个值,与线性函数计算器相关联的差分计算器,被配置为计算线性函数和多个 接收到的与时间有关的值,以及与差分计算器相关联的转换点标识符,其被配置为使用所计算的差异来识别化学反应的至少一个转变点。
    • 4. 发明申请
    • IDENTIFYING OUTLIERS AMONG CHEMICAL ASSAYS
    • 鉴定化学测定的出处
    • WO2012150524A1
    • 2012-11-08
    • PCT/IB2012/052030
    • 2012-04-23
    • RUSSAK, Ze'evAZURE VAULT LTD
    • RUSSAK, Ze'ev
    • C12Q1/68
    • G01N31/10G06F19/24
    • An apparatus for identifying outliers among chemical reaction assays, the apparatus comprising a transition point finder, configured to find at least one transition point in a cumulative function, the cumulative function giving a quantitative indication based on a count of points in a calculated space as a function of distance from a function dividing the calculated space into at least two groups, each one of the points representing results of a respective assay of a chemical reaction. The apparatus further comprises an outlier identifier, in communication with the transition point finder, configured to use a distance of the found transition point from the function dividing the calculated space, as a threshold, for identifying an outlier among the chemical reaction assays.
    • 一种用于识别化学反应测定中的异常值的装置,所述装置包括转换点查找器,其被配置为找到累积函数中的至少一个转变点,所述累积函数基于计算空间中的点数计算为定量指示,作为 从将计算出的空间分成至少两组的函数的距离的函数,每个点表示化学反应的相应测定的结果。 该装置还包括与转换点查找器通信的异常值标识符,其被配置为使用从所计算的空间除以函数的所找到的转换点的距离作为阈值,用于识别化学反应测定中的异常值。
    • 5. 发明申请
    • RATE BASED IDENTIFICATION OF REACTION POINTS
    • 基于速率的反应点识别
    • WO2012123895A1
    • 2012-09-20
    • PCT/IB2012/051182
    • 2012-03-13
    • RUSSAK, Ze'evAZURE VAULT LTD
    • RUSSAK, Ze'ev
    • C12Q1/68
    • C12Q1/686G06F19/702
    • An apparatus for identifying transition points in a chemical reaction, the apparatus comprising: a property value receiver, configured to receive a plurality of values of a physical property of the chemical reaction, a function calculator, associated with the property value receiver, configured to calculate a function and verify that the function has a line of best fit with a same slope as a linear function connecting two of the received values, the two values pertaining to a start and end of a time period, a difference calculator, associated with the function calculator, configured to calculate a difference between the calculated function and a plurality of the received values pertaining to the time period having the start and end, and a transition point identifier, associated with the difference calculator, configured to identify at least one transition point of the chemical reaction, using the calculated difference.
    • 一种用于识别化学反应中的转变点的装置,所述装置包括:属性值接收器,被配置为接收所述化学反应的物理性质的多个值,与所述属性值接收器相关联的函数计算器,被配置为计算 函数,并验证该函数具有与连接两个接收值的线性函数相同斜率的最佳拟合线,与时间段的开始和结束相关的两个值,与该函数相关联的差分计算器 计算器,被配置为计算所计算的函数和与具有开始和结束的时间段有关的多个接收值之间的差异,以及与差分计算器相关联的转换点标识符,其被配置为识别至少一个转换点 化学反应,使用计算的差异。
    • 7. 发明申请
    • CUMULATIVE DIFFERENTIAL CHEMICAL ASSAY IDENTIFICATION
    • 累积差分化学测定鉴定
    • WO2013054288A1
    • 2013-04-18
    • PCT/IB2012/055517
    • 2012-10-11
    • RUSSAK, Ze'evAZURE VAULT LTD
    • RUSSAK, Ze'ev
    • G01N25/04
    • G06F19/20C12Q1/6816C12Q1/6851C12Q1/686G01N21/64G01N21/6428G06F19/702C12Q2527/107C12Q2537/165C12Q2563/107
    • An apparatus comprising: a value receiver, configured to receive fluorescence values measured during a chemical reaction involving a test sample, each value pertaining to a respective physical parameter value, a difference calculator, configured to calculate differences, each difference being between respective one of the measured fluorescence values and one of reference fluorescence values of a reference sample, each reference fluorescence value pertaining to a respective physical parameter value, a cumulative index calculator, configured to calculate a cumulative index, by selecting a first difference among the calculated differences, and selecting and adding to the first difference differences, each one of the added differences being selected according to a proximity standard applied on each two differences selected in a sequence, the proximity standard being based on proximity of physical parameter values and difference size, and a similarity determiner, configured to determine similarity between the samples, using the calculated cumulative index.
    • 一种装置,包括:值接收器,被配置为接收在涉及测试样本的化学反应期间测量的荧光值,与相应物理参数值相关的每个值,差分计算器,被配置为计算差异,每个差异在 测量荧光值和参考样品的参考荧光值之一,与相应物理参数值相关的每个参考荧光值,累积指数计算器,被配置为通过选择计算出的差异中的第一差异来选择累积指数,并选择 并且添加到所述第一差异差异中,根据应用于在序列中选择的每个两个差异的接近度标准来选择每个所述相加的差异,所述接近度标准基于物理参数值和差异大小的接近度,以及相似性确定器 ,配置为确定sim 样本之间的不一致,使用计算的累积指数。