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    • 2. 发明申请
    • NOVEL SYNERGISTIC COMPOSITION COMPRISING OF A CAROTENOID, SERM AND AN AMINO ACID DERIVATIVE THEREOF
    • 含有碳酸ID,,,OF OF OF OF OF OF OF OF OF OF OF OF OF OF OF OF OF OF OF OF OF OF OF OF
    • WO2013160914A1
    • 2013-10-31
    • PCT/IN2013/000277
    • 2013-04-23
    • RAMANAN, Ezhil Arasan
    • RAMANAN, Ezhil Arasan
    • A61K31/122A61K31/138A61K31/198A61P15/08
    • A61K31/122A61K31/138A61K31/198A61K2300/00
    • The present invention refers to a combination for ovulation induction and infertility in women. The present invention particularly relates to a synergistic composition comprising a carotenoid, and an antioxidant over and above an agent that induces ovulation. The synergistic composition for inducing ovulation comprising a combination of antioxidants with a carotenoid and a selective estrogen receptor modulator (SERM) or an aromatase inhibitor. The present invention preferably refers to Astaxanthin and N acetyl cysteine added to the regular treatment of a selective estrogen receptor modulator and an aromatase inhibitor. More specifically, the invention relates to the use of such synergistic composition for inducing ovulation thereby increasing the pregnancy outcome with the complete management of infertility in particular in females who are disposed and predisposed to amenorrhea, hormonal imbalance, irregular menstruation, hyperinsulinemia related manifestations, obesity, PCOS, endometriosis and other factors.
    • 本发明涉及妇女排卵诱导和不育的组合。 本发明特别涉及一种包含类胡萝卜素和抗氧化剂的协同组合物,所述组合物在诱导排卵的试剂上和上方。 用于诱导排卵的协同组合物包含抗氧化剂与类胡萝卜素和选择性雌激素受体调节剂(SERM)或芳香酶抑制剂的组合。 本发明优选地是指加入到选择性雌激素受体调节剂和芳香酶抑制剂的常规治疗中的虾青素和N-乙酰半胱氨酸。 更具体地,本发明涉及这种协同组合物用于诱导排卵的用途,从而通过完全不孕症的管理来增加妊娠结局,特别是在处置并易于闭经,激素失调,不规则月经,高胰岛素血症相关表现,肥胖症的女性中 ,PCOS,子宫内膜异位症等因素。