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1. 发明申请

WO2018009582A1 POROUS METAL DEVICES 审中-公开
标题翻译：多孔金属器件
公开(公告)号：WO2018009582A1
公开(公告)日：2018-01-11
申请号：PCT/US2017/040770
申请日：2017-07-05
申请人： POROSTEON DEVELOPMENT LLC
发明人： AIHARA, Hokuto , ZIDER, John , ZIDER, Robert, B , FANTON, Gary, S. , CARPENTER, Scott , DUERIG, Thomas
IPC分类号： B22F3/23 , C22C1/08 , A61L27/04 , A61L27/14 , A61L27/56
摘要： Devices comprising a component which has an open porous structure composed of an alloy of nickel and titanium or a mixture of nickel and titanium. The devices can be implanted in a mammalian body and provide desired interaction with protein, blood, ions, bone cells, and tissue. The devices are particularly useful for providing a substrate for the ingrowth of bone. In the open pore structure, preferably more than 95 % of the pores having a size of 50-1000 pm, particularly 50-600 μητι, with a pore size standard deviation of 250 μητι or less, particularly of 150 pm or less, and an average porosity by volume of 40-80%. When the device is implanted adjacent to a cancellous bone, the porous component preferably has a modulus of 0.1-1.2 GPa. When the device is implanted adjacent to cortical bone, the porous component preferably has a modulus of 16 to 24 GPa. The devices are also useful for filtering a liquid.
摘要翻译：包括具有由镍和钛的合金或镍和钛的混合物构成的开放式多孔结构的器件的器件。这些装置可以植入哺乳动物体内并提供与蛋白质，血液，离子，骨细胞和组织的所需相互作用。这些装置对于为骨头向内生长提供基材特别有用。在开孔结构中，优选具有50-1000微米，特别是50-600微米的尺寸的孔的95％以上，孔尺寸标准偏差为250微米或更小，特别是150微米或更小，以及平均孔隙率按体积计为40-80％。当装置邻近松质骨植入时，多孔部件优选具有0.1-1.2GPa的模量。当装置邻近皮质骨植入时，多孔部件优选具有16至24GPa的模量。这些设备也可用于过滤液体。

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