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1. 发明申请

WO2022051165A1 OIL-IN-WATER EMULSION GUMMY COMPOSITION 审中-公开
公开(公告)号：WO2022051165A1
公开(公告)日：2022-03-10
申请号：PCT/US2021/047732
申请日：2021-08-26
申请人： PHARMAVITE LLC
发明人： GE, Haiyan , PACHECO, Javier
IPC分类号： A23L33/115 , A23G3/34 , A23L27/10 , A23L29/238 , A23L29/256 , A23L29/281 , A23L33/15 , A23L33/16
摘要： A gummy composition including a set emulsification of an oil phase in a water phase, wherein the water phase comprises a structurant, and wherein the gummy composition has a hardness of 150 gForce or greater and a water activity below 0.73. A method including administering a gummy composition including a set emulsification of an oil phase in a water phase and the gummy composition includes a hardness of 150 gForce or greater and a water activity below 0.73.

2. 发明申请

WO2014059045A1 NATURAL COATING FORMULAS AND COMPOSITION FOR COATING TABLETS 审中-公开
标题翻译：自然涂料配方和涂料组合物
公开(公告)号：WO2014059045A1
公开(公告)日：2014-04-17
申请号：PCT/US2013/064173
申请日：2013-10-09
申请人： PHARMAVITE LLC
发明人： WANG, Linji , MORIN, Louis A. , ROPER, Douglas R. , DOWNING, Kendall M.
IPC分类号： A61K9/28 , A61K9/34 , A61K9/48 , A61J3/06
CPC分类号： A61K47/38 , A61J3/005 , A61K9/2866 , A61K9/288 , A61K47/44 , A61K47/46
摘要： A solid dosage form coating composition including gray oyster shell powder in a form suitable to be coated on a solid dosage form. A method including coating a solid dosage form with a coating composition comprising gray oyster shell powder; and drying the coating composition into a film.
摘要翻译：一种固体剂型涂料组合物，其包含适于涂覆在固体剂型上的形式的灰牡蛎壳粉末。一种包括用包含灰蚝壳粉末的涂料组合物涂覆固体剂型的方法; 并将涂料组合物干燥成膜。

3. 发明申请

WO2021226541A1 GELATIN AND PECTIN GUMMY COMPOSITION FOR STARCHLESS PRODUCTION 审中-公开
公开(公告)号：WO2021226541A1
公开(公告)日：2021-11-11
申请号：PCT/US2021/031419
申请日：2021-05-07
申请人： PHARMAVITE, LLC
发明人： GE, Haiyan , WU, Yan
IPC分类号： A23G3/34 , A23G3/36 , A23G3/48 , A23L29/231 , A23L29/281
摘要： A gummy composition including a gelatin; a pectin; a food-grade organic acid; and water, wherein the gummy composition has a pH of 3.1 to 3.45 or a Brix range of 76 to 81, and wherein the gummy composition has a removal time of 30 minutes or less in a starchless mold.

4. 发明申请

WO2010132767A1 REMOVABLE COUPON AND METHODS OF MANUFACTURE 审中-公开
标题翻译：可拆卸机架及其制造方法
公开(公告)号：WO2010132767A1
公开(公告)日：2010-11-18
申请号：PCT/US2010/034895
申请日：2010-05-14
申请人： PHARMAVITE LLC , ATKIN, Gail, V.
发明人： ATKIN, Gail, V.
IPC分类号： B65D51/24 , B65D55/06
CPC分类号： B65D51/245 , B65D55/066 , B65D2203/00 , B65D2251/0015 , B65D2251/0093
摘要： A container assembly (100) including a composite inner seal (120) with a removable coupon (135) affixed thereon by a pressure-sensitive agent, thus sealing an opening of the container is disclosed. In some embodiments, the removable coupon (135) is capable of being removed intact. Methods of manufacturing a container assembly (100) including fabricating an inner composite seal (120) and a removable coupon (135) are disclosed. The removable component (135) is removably affixed to a top surface of the inner composite seal (120) by application of a pressure-sensitive agent thus forming a multi-layered seal. The multi-layered seal may be positioned and/or inserted within a container cap (125) in preparation for completing downstream bottling of a medicinal substance. Methods of providing a product/residue-free removable coupon (135) to a user wherein the removable coupon (135) is included within the container assembly, but free from contact with the product within the container are disclosed. In some embodiments, the removable coupon is provided as a removable component affixed to a composite inner seal (120) that seals an opening of the container (100).
摘要翻译：公开了一种容器组件（100），其包括具有通过压敏粘合剂固定在其上的可拆卸试样（135）的复合内密封件（120），从而密封容器的开口。在一些实施例中，可移除优惠券（135）能够被完整地移除。公开了制造包括制造内部复合密封件（120）和可拆卸试样（135）的容器组件（100）的方法。通过施加压敏剂从而形成多层密封，可移除部件（135）可移除地固定到内复合密封件（120）的顶表面。多层密封件可以定位和/或插入容器盖（125）内，以准备完成药物的下游装瓶。向使用者提供产品/无残留物的可拆卸试样（135）的方法，其中可拆卸试样（135）包括在容器组件内，但不与容器内的产品接触。在一些实施例中，可拆卸附件被提供为固定到密封容器（100）的开口的复合内密封件（120）的可移除部件。

5. 发明申请

WO2023069761A1 TRIBUTYRIN SUPPLEMENTATION PROVIDES BENEFITS FOR MENTAL WELLNESS, IMMUNE HEALTH AND FAT METABOLISM 审中-公开
公开(公告)号：WO2023069761A1
公开(公告)日：2023-04-27
申请号：PCT/US2022/047501
申请日：2022-10-22
申请人： PHARMAVITE LLC
发明人： SHARMA, Vandana , MITMESSER, Susan Hazels
IPC分类号： A23L33/115
摘要： A method of improving mood, improving coping with stress, improving metabolism, and/or improving immune system function including administering of an amount of tributyrin to or by a subject sufficient to release at least a portion of butyrate from the administered amount in the small intestine of the subject to improve a mood, improve a coping with stress, improve a metabolism and/or improve an immune system function of the subject. A method of improving mood, improving coping with stress, improving metabolism, and/or improving immune system function including administering of an amount of tributyrin to or by a subject sufficient to release a first portion of butyrate from the administered amount in the small intestine of the subject and a second portion of butyrate in the colon to improve mood, improve coping with stress, improve a metabolism and/or improve an immune system function of the subject. A dietary supplement composition comprising an amount of tributyrin sufficient to release at least a portion of butyrate in the small intestine and a second portion in colon.

6. 发明申请

WO2022036121A1 PREBIOTIC COMPOSITION OF PECTIN, BETA-GLUCAN, XYLOOLIGOSACCHARIDE AND/OR ASHWAGANDHA AND A METHOD OF IMPROVING MOOD 审中-公开
公开(公告)号：WO2022036121A1
公开(公告)日：2022-02-17
申请号：PCT/US2021/045777
申请日：2021-08-12
申请人： PHARMAVITE, LLC
发明人： SHARMA, Vandana , MITMESSER, Susan Hazels
IPC分类号： A61K9/00 , A61K9/20 , A61K31/732 , A61K9/48 , A61K31/715 , A61K31/716 , A61K36/00 , A61P25/00 , A61P25/22 , A61P25/24 , A61P43/00 , C08B37/00
摘要： A composition and a method for improving mood, particularly reducing stress, anxiety and/or depression including administering a composition including at least two prebiotics selected from a source of pectin, a source of beta-glucan, a source of xylooligosaccharide and Ashwagandha. The composition may be in the form of a supplement that is added to a diet (supplements a normal human diet). The composition includes the at least two prebiotics in an amount to increase production of (A) tryptophan or (B) tryptophan and/or at least one of (i) indole, (ii) an indole derivative, (iii) 2,3-pyridinecarboxylic acid (iv) 3-(4-hydroxyphenyl) propionic acid and (v) a short chain fatty acid or (C) any other metabolite (e.g., dopamine, serotonin, GABA) relevant to (eg. benefitting) brain health such as improving mood.

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