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1. 发明申请

WO0200496A9 FLOATING PLATFORM FOR OFFSHORE DRILLING OR PRODUCTION OF HYDROCARBONS 审中-公开
标题翻译：用于海上钻井或生产石油的浮动平台
公开(公告)号：WO0200496A9
公开(公告)日：2003-01-23
申请号：PCT/NO0100266
申请日：2001-06-22
申请人： MOSS MARITIME AS , KRISTENSEN PER HERBERT , HUSEM IDA , PETTERSEN ERIK
发明人： KRISTENSEN PER HERBERT , HUSEM IDA , PETTERSEN ERIK
IPC分类号： B63B35/44
CPC分类号： B63B35/4413
摘要： A floating platform for offshore drilling or production of hydrocarbons comprises a topsides with drilling and/or production equipment (8), and a substructure comprising a lower pontoon (3) and columns (4) connecting the pontoon (3) to the topsides (1). During its operation the platform is exposed to wave forces (9) which cause heave motion (v) and roll and pitch motion (p) of the platform. The substructure has a draught (11) which is at least 40 metres, preferably at least 50 metres and most preferred at least 60 metres, and the ratio between the distance (16) between the columns' centre axes (25), measured along a side of the substructure, and the lower substructure's draught (11) is between 1.0 and 1.5, preferably between 1.2 and 1.4 and most preferred between 1.3 and 1.35.
摘要翻译：用于海上钻井或生产碳氢化合物的浮动平台包括具有钻井和/或生产设备（8）的顶部，以及包括将浮筒（3）连接到顶板（1）的下浮筒（3）和柱（4）的子结构）。在其操作期间，平台暴露于引起平台的起伏运动（v）和滚动和俯仰运动（p）的波浪力（9）。子结构具有至少40米，优选至少50米，最优选至少60米的吃水（11），以及沿着下部结构的通气口（11）在1.0和1.5之间，优选在1.2和1.4之间，最优选在1.3和1.35之间。

2. 发明申请

WO1992009276A1 AROMATIC ALDEHYDES AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL FOR THE TREATMENT OF SKIN DISEASES AND ARTHRITIS 审中-公开
标题翻译：芳香醛和衍生物及其用于治疗皮肤疾病和神经病的药物组合物
公开(公告)号：WO1992009276A1
公开(公告)日：1992-06-11
申请号：PCT/NO1991000147
申请日：1991-11-25
申请人： NORSK HYDRO A.S , BORRETZEN, Bernt , PETTERSEN, Erik, Olai , LARSEN, Rolf, Olav , DORNISH, John, Michael , RAMDAHL, Thomas , OFTEBRO, Reidar
发明人： NORSK HYDRO A.S
IPC分类号： A61K31/11
CPC分类号： A61K31/7004 , A61K31/11 , A61K31/365 , A61K31/505
摘要： The use of compounds of formula (I) for the treatment of cells having an abnormally elevated cell proliferation, which results in diseases such as psoriasis, inflammatory diseases, rheumatic diseases and allergic dermatologic reactions.
摘要翻译：使用式（I）化合物治疗具有异常升高的细胞增殖的细胞，其导致诸如牛皮癣，炎性疾病，风湿性疾病和变态反应皮肤病反应的疾病。

3. 发明申请

WO2011098610A1 CARBONIC ANHYDRASE INHIBITORS 审中-公开
标题翻译：碳酸酐酶抑制剂
公开(公告)号：WO2011098610A1
公开(公告)日：2011-08-18
申请号：PCT/EP2011/052156
申请日：2011-02-14
申请人： UNIVERSITA DEGLI STUDI DI FIRENZE , UNIVERSITETET I OLSO , UNIVERSITY OF MANCHESTER , EBBESEN, Peter , SUPURAN, Claudiu T. , SCOZZAFAVA, Andrea , PETTERSEN, Erik Olai , WILLIAMS, Kaye , PASTOREKOVA, Silvia , DUBOIS, Ludwig , LAMBIN, Philippe
发明人： EBBESEN, Peter , SUPURAN, Claudiu T. , SCOZZAFAVA, Andrea , PETTERSEN, Erik Olai , WILLIAMS, Kaye , PASTOREKOVA, Silvia , DUBOIS, Ludwig , LAMBIN, Philippe
IPC分类号： A61K31/18 , A61P35/00 , C07C311/00
CPC分类号： A61K49/0021 , C07C307/02 , C07C307/10 , C07C335/18 , C07C2601/14
摘要： A carbonic anhydrase IX (CA IX) inhibitor which comprises a compound of general formula: R-NH-CX-NH-(CH 2 ) n -Ar-Q-SO 2 -NH 2 or a pharmaceutically-acceptable salt, derivative or prodrug thereof; wherein n = 0, 1 or 2; Q is O or NH; X is O or S; and R comprises an organic substituent group.
摘要翻译：包含通式为：R-NH-CX-NH-（CH2）n-Ar-Q-SO2-NH2的化合物或其药学上可接受的盐，衍生物或前药的碳酸酐酶IX（CA IX）抑制剂; 其中n = 0,1或2; Q是O或NH; X为O或S; R包含有机取代基。

4. 发明申请

WO2005085059A1 FLOATING STRUCTURE 审中-公开
标题翻译：浮动结构
公开(公告)号：WO2005085059A1
公开(公告)日：2005-09-15
申请号：PCT/NO2005/000074
申请日：2005-03-02
申请人： MOSS MARITIME AS , KRISTENSEN, Per, Herbert , PETTERSEN, Erik , HUSEM, Ida , SKOGEN, Tor
发明人： KRISTENSEN, Per, Herbert , PETTERSEN, Erik , HUSEM, Ida , SKOGEN, Tor
IPC分类号： B63B39/06
CPC分类号： B63B35/44 , B63B22/021
摘要： The present invention relates to a floating loading buoy (1) comprising a surface element (2), columns (3) connecting the surface element (2) to a submerged pontoon element (4), mooring devices (5) for securing the loading buoy (1) to the seabed (6), at least one attachment point (7) for transfer pipelines (8) from a production/processing/storage unit (9) to the loading buoy (1), mooring and transfer devices (10) for transferring fluid from the loading buoy (1) to a loading/unloading vessel (11). The surface element (2) is arranged floating in the water plane surface (12) and has a substantially rounded cross section in a substantially horizontal plane and a draught in the body of water, the columns (3) extend from the surface element (2) down to the pontoon element (4), which in a substantially horizontal plane has a substantially rounded external perimeter and a draught in the body of water. The proportion of the volume of the pontoon element (4) divided by the waterline area of the surface element (2) is in the range 4-7m, and preferably approximately 6m, and the draught of the surface element (2) divided by the draught of the pontoon element (4) is in the range 0.31-0.43 and where the vertical mooring rigidity for the loading buoy (1) is over 50% of the waterline rigidity for the loading buoy (1).
摘要翻译：本发明涉及一种浮动装载浮标（1），其包括表面元件（2），将表面元件（2）连接到淹没的浮筒元件（4）的柱（3），用于固定装载浮标的系泊装置（5）（1）到海底（6），用于从生产/处理/储存单元（9）到装载浮标（1），系泊和转移装置（10）的输送管线（8）的至少一个附接点（7）用于将流体从装载浮标（1）传送到装载/卸载容器（11）。表面元件（2）布置成浮在水平面（12）中，并且具有基本水平的平面中的基本圆形横截面和水体中的通风，柱（3）从表面元件（2）延伸）到浮体元件（4），其在基本上水平的平面中具有基本上圆形的外部周边和在水体中的通风。浮子元件（4）的体积除以表面元件（2）的水线面积的比例在4-7m的范围内，优选地约6m，并且表面元件（2）的通风量除以浮子元件（4）的通风范围为0.31-0.43，装载浮标（1）的垂直系泊刚度高于装载浮标（1）的水线刚度的50％以上。

5. 发明申请

WO2004067372A1 FLOATING STRUCTURE 审中-公开
标题翻译：浮动结构
公开(公告)号：WO2004067372A1
公开(公告)日：2004-08-12
申请号：PCT/NO2004/000021
申请日：2004-01-26
申请人： MOSS MARITIME AS , KRISTENSEN, Per, Herbert , PETTERSEN, Erik
发明人： KRISTENSEN, Per, Herbert , PETTERSEN, Erik
IPC分类号： B63B21/50
CPC分类号： B63B39/00 , B63B1/107 , B63B21/50 , B63B2039/067
摘要： The invention relates to a floating structure 1, for instance a semi submersible platform, comprising a deck structure 2, vertical columns 3 and a pontoon structure 4. The floating structure 1 is moored to the seabed with anchor lines 7. The mooring of the floating structure is done with taut line anchoring system, where the vertical stiffness in the anchoring system is approximately 20% of the water plane stiffness for the floating structure. The invention also relates to a floating structure as described above where the pontoon structure 4 comprises at least two levels of pontoons and where the columns 3 are formed to give variable water plane stiffness.
摘要翻译：本发明涉及浮动结构1，例如半潜式平台，其包括甲板结构2，垂直立柱3和浮桥结构4.浮动结构1通过锚定线7停泊在海床上。浮动系泊系泊结构采用拉紧锚固系统，其中锚固系统中的垂直刚度大约为浮动结构的水平面刚度的20％。本发明还涉及如上所述的浮动结构，其中浮筒结构4包括至少两层浮筒，并且其中塔3形成以提供可变的水平面刚度。

6. 发明申请

WO0228704A9 PLATFORM STRUCTURE 审中-公开
标题翻译：平台结构
公开(公告)号：WO0228704A9
公开(公告)日：2002-06-06
申请号：PCT/NO0100403
申请日：2001-10-02
申请人： MOSS MARITIME AS , KRISTENSEN PER HERBERT , HUSEM IDA , PETTERSEN ERIK
发明人： KRISTENSEN PER HERBERT , HUSEM IDA , PETTERSEN ERIK
IPC分类号： B63B1/10 , B63B35/44
CPC分类号： B63B35/4413 , B63B1/107 , B63B2001/126 , B63B2001/128
摘要： The invention relates to a floating platform (1) for offshore drilling or production of hydrocarbons, comprising a topsides (2) and a structure (3) having a lower pontoon (4) and columns (5) connecting the pontoon (4) to the topsides (2). Heave motion (S1, S2) of the platform (1) causes a change in the metacentric height (GM) of the platform. To counteract this change in metacentric height, the columns (5) are so adapted that the moment of area inertia of the waterline area of the columns (5) decreases on downward heave motion (S1) abd increaes on upward heave motion (S2.
摘要翻译：本发明涉及用于海上钻井或生产碳氢化合物的浮动平台（1），其包括顶部（2）和具有下浮筒（4）的结构（3）和将浮筒（4）连接到上侧（2）。平台（1）的升降运动（S1，S2）导致平台的中心高度（GM）的变化。为了抵消中心高度的这种变化，列（5）适于使得列（5）的水线区域的面积惯性力矩随着向下的升沉运动（S1）abd而减小。

7. 发明申请

WO1995018607A1 PHARMACEUTICAL COMPOSITIONS 审中-公开
标题翻译：药物组合物
公开(公告)号：WO1995018607A1
公开(公告)日：1995-07-13
申请号：PCT/NO1995000003
申请日：1995-01-03
申请人： NORSK HYDRO A.S , PETTERSEN, Erik, Olai , LARSEN, Rolf, Olaf , DORNISH, John, Michael , BORRETZEN, Bernt , OFTEBRO, Reidar , RAMDAHL, Thomas , MOEN, Vidar
发明人： NORSK HYDRO A.S
IPC分类号： A61K31/19
CPC分类号： A61K31/38 , A61K31/22 , A61K31/275 , A61K31/335 , A61K31/34 , A61K31/44
摘要： Pharmaceutical compositions which are useful for the treatment of cancer or illnesses which arise due to an abnormally elevated cell proliferation comprise acyl derivatives of aromatic aldehydes, especially arylidene diesters and alpha -alkoxyarylidene esters of general formula (I).
摘要翻译：可用于治疗由于异常升高的细胞增殖而引起的癌症或疾病的药物组合物包括芳族醛的酰基衍生物，特别是亚芳基二酯和通式（I）的α-烷氧基亚芳基酯。

8. 发明申请

WO2013050426A1 CARBONIC ANHYDRASE INHIBITOR COMPRISING A DITHIOCARBAMATE 审中-公开
标题翻译：含有二异氰酸酯的碳酸酐类抑制剂
公开(公告)号：WO2013050426A1
公开(公告)日：2013-04-11
申请号：PCT/EP2012/069548
申请日：2012-10-03
申请人： UNIVERSITETET I OSLO , UNIVERSITA DEGLI STUDI DI FIRENZE , SUPURAN, Claudiu, T. , SCOZZAFAVA, Andrea , MASINI, Emanuela , CARTA, Fabrizio , PETTERSEN, Erik, Olai , EBBESEN, Peter
发明人： SUPURAN, Claudiu, T. , SCOZZAFAVA, Andrea , MASINI, Emanuela , CARTA, Fabrizio , PETTERSEN, Erik, Olai , EBBESEN, Peter
IPC分类号： A61K31/145 , A61K31/198 , A61K31/325 , A61K31/40 , A61K31/401 , A61K31/417 , A61K31/426 , A61K31/4409 , A61K31/4453 , A61K31/451 , A61K31/495 , A61K31/5375 , C07C333/16 , A61P31/00 , A61P31/06
CPC分类号： A61K31/145 , A61K31/198 , A61K31/325 , A61K31/40 , A61K31/401 , A61K31/417 , A61K31/426 , A61K31/4409 , A61K31/4453 , A61K31/451 , A61K31/495 , A61K31/5375 , C07C333/16 , C07D207/16 , C07D211/64 , C07D213/40 , C07D233/61 , C07D277/48 , C07D295/108 , C07D295/13 , C07D295/24 , C07D295/32
摘要： A carbonic anhydrase inhibitor which comprises a compound of general formula: R 1 R 2 N-CS 2 - M + for use in the treatment of microbial infection, eye disease or cancer; wherein R 1 and R 2 are each independently selected from H or an organic substituent, or together form a ring, and optionally contain one or more heteroatoms; wherein R and R 2 together comprise at least 5 carbon atoms or at least 2 carbon atoms and a heteroatom, or R 2 comprises at least 4 carbon atoms; and wherein M + comprises a monovalent cation.
摘要翻译：一种碳酸酐酶抑制剂，其包含用于治疗微生物感染，眼病或癌症的通式为R1R2N-CS2-M +的化合物; 其中R 1和R 2各自独立地选自H或有机取代基，或一起形成环，并且任选地含有一个或多个杂原子; 其中R和R 2一起包含至少5个碳原子或至少2个碳原子和杂原子，或者R 2包含至少4个碳原子; 并且其中M +包含一价阳离子。

9. 发明申请

WO2012117107A1 METHOD OF DETERMINING WETHER A SUBJECT IS RESISTANT TO CHEMOTHERAPY WITH DNA DAMAGING AGENTS 审中-公开
标题翻译：确定一个主题的方法可以抵抗DNA损伤剂的化学疗法
公开(公告)号：WO2012117107A1
公开(公告)日：2012-09-07
申请号：PCT/EP2012/053674
申请日：2012-03-02
申请人： UNIVERSITETET I OSLO , EDIN, Nina, F., Jeppesen , PETTERSEN, Erik, Olai , SANDVIK, Joe, Alexander , EBBESEN, Peter
发明人： EDIN, Nina, F., Jeppesen , PETTERSEN, Erik, Olai , SANDVIK, Joe, Alexander , EBBESEN, Peter
IPC分类号： G01N33/50
CPC分类号： G01N33/5011 , G01N33/5091 , G01N2333/4703 , G01N2800/40 , G01N2800/44 , G01N2800/52
摘要： The present invention relates to a method for determining whether a subject is resistant to certain types of chemotherapy, specifically chemotherapy in which DNA damaging agents are used. A method of determining whether a subject is resistant to chemotherapy with DNA damaging agents, said method comprising determining whether a sample from said subject is capable of reducing the low dose hyper-radiosensitivity (HRS) phenotype in HRS proficient cells, said subject being resistant to said chemotherapy if said sample is capable of reducing the HRS phenotype in HRS proficient cells is provided. Preferred methods involve detection of free extracellular TGβ3 in said sample, determining whether the sample has the ability to increase cell survival in cells in response to radiation that induces the HRS phenotype in HRS proficient cells and determining whether said sample has the ability to decrease the mitotic ratio and/or mitotic ratio (irradiated cells/unirradiated cells) in cells in response to radiation that induces the HRS phenotype in HRS proficient cells.
摘要翻译：本发明涉及一种用于确定受试者是否耐受某些类型的化疗，特别是使用DNA损伤剂的化学疗法的方法。一种确定受试者是否耐受DNA损伤剂的化学疗法的方法，所述方法包括确定来自所述受试者的样品是否能够降低HRS精通细胞中的低剂量超辐射敏感性（HRS）表型，所述受试者耐受如果所述样品能够降低HRS精液细胞中的HRS表型，则表示化疗。优选的方法包括检测所述样品中的游离细胞外TGβ3，确定样品是否具有增加细胞响应于在HRS精通细胞中诱导HRS表型的辐射的细胞存活的能力，并确定所述样品是否具有减少有丝分裂的能力比例和/或有丝分裂比（照射细胞/未照射细胞）在细胞中响应于在HRS精通细胞中诱导HRS表型的辐射。

10. 发明申请

WO2003002404A1 SUBSTRUCTURE FOR A FLOATING OFFSHORE PLATFORM 审中-公开
标题翻译：浮动海洋平台的基础
公开(公告)号：WO2003002404A1
公开(公告)日：2003-01-09
申请号：PCT/NO2002/000228
申请日：2002-06-24
申请人： MOSS MARITIME AS , KRISTENSEN, Per, Herbert , PETTERSEN, Erik
发明人： KRISTENSEN, Per, Herbert , PETTERSEN, Erik
IPC分类号： B63B35/44
CPC分类号： B63B35/4413 , B63B1/107 , B63B2001/123 , B63B2001/128
摘要： A substructure for a floating offshore platform comprises one or more lower pontoons (1) and substantially vertical columns (2) with a substantially constant cross sectional area projecting upwards from the pontoon(s) (1). The substructure is exposed in the water (13) to wave forces that induce heave motion of the substructure. The substructure may be provided with a central column (3) with a conical portion (4), which during heave motion moves through the surface of the water. Alternatively, the substructure may be provided with conical elements that are mounted on the outside of one or more of the columns (2), forming one or more conical portions, which during heave motion move through the surface of the water.
摘要翻译：用于浮动海上平台的子结构包括一个或多个下浮筒（1）和基本上垂直的柱（2），其具有从浮筒（1）向上突出的基本恒定的横截面面积。子结构暴露在水（13）中以产生引起下结构起伏运动的波浪力。底部结构可以设置有具有锥形部分（4）的中心柱（3），其在升起运动期间移动通过水面。或者，子结构可以设置有锥形元件，其安装在一个或多个柱（2）的外侧上，形成一个或多个锥形部分，其在升起运动期间移动通过水的表面。

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