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1. 发明申请

WO2011019545A1 MEDICAL DEVICE AND METHOD OF MANUFACTURING SAME 审中-公开
标题翻译：医疗装置及其制造方法
公开(公告)号：WO2011019545A1
公开(公告)日：2011-02-17
申请号：PCT/US2010/044242
申请日：2010-08-03
申请人： WILLIAM COOK EUROPE APS , COOK INCORPORATED , PETERSEN, Jesper, Schade
发明人： PETERSEN, Jesper, Schade
IPC分类号： A61F2/06 , A61F2/82
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/075 , A61F2002/8483 , A61F2220/0075
摘要： An implantable medical device (24) includes a graft member (26), at least one stent (10) and at least one barb element (12). The stent (10) has wrapped therearound a barb element (12) formed of a length of at least one wire provided with first and second ends (14, 16) forming barb prongs. In an intermediate zone (22), the barb element (12) is wrapped or coiled. The two pronged ends (14, 16) extend out of the graft element (26) to provide an anchoring function to the medical device. As well as being wrapped onto a strut of the stent (10), the barb element (12) is sutured to the stent (10) and to the graft material (26) by suture stitching (28). The turns of the coiling or wrapping in intermediate section (22) assist in fixing the barb element (12) relative to the suture (28) and thus to the stent graft (24). The barb elements (12) could be made of any suitable material, including Nitinol.
摘要翻译：植入式医疗装置（24）包括移植件（26），至少一个支架（10）和至少一个倒钩元件（12）。支架（10）已经包围由设置有形成倒刺的第一和第二端（14,16）的至少一根线的长度形成的倒钩元件（12）。在中间区域（22）中，倒钩元件（12）被包裹或卷绕。两个叉头端部（14,16）从移植物元件（26）延伸出来，以向医疗装置提供锚定功能。除了被包裹到支架（10）的支柱之外，倒钩元件（12）通过缝合缝合（28）被缝合到支架（10）和移植物材料（26）。卷绕或卷绕在中间部分（22）中的匝有助于相对于缝合线（28）固定倒钩元件（12），从而有助于将支架移植物（24）固定。倒钩元件（12）可以由任何合适的材料制成，包括镍钛诺。

2. 发明申请

WO2010126964A1 INTRODUCER ASSEMBLY AND METHOD OF MANUFACTURING AN INTRODUCER ASSEMBLY 审中-公开
标题翻译：引言组件和制造引言组件的方法
公开(公告)号：WO2010126964A1
公开(公告)日：2010-11-04
申请号：PCT/US2010/032704
申请日：2010-04-28
申请人： WILLIAM COOK EUROPE APS , COOK INCORPORATED , RASMUSSEN, Erik, Edelboe , OEHLENSCHLAEGER, Bent , PETERSEN, Jesper, Schade
发明人： RASMUSSEN, Erik, Edelboe , OEHLENSCHLAEGER, Bent , PETERSEN, Jesper, Schade
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2250/0071 , Y10T29/49826
摘要： An introducer assembly (10) includes a guide wire catheter (12), a pusher element (16), an external manipulation unit (28) and an external sheath (30). The distal end (18) of the pusher element (16) is bonded, with adhesive or other bonding agent (32), to the guide wire catheter (12) so as to fix these components together at the distal end (18) of the pusher element (16). This reduces twisting of the pusher element (16) relative to the guide wire catheter (12) and thus twisting of any implantable medical device carried on the introducer assembly (10). This can reduce incorrect deployment of the implantable medical device and reduce instances of an abortive medical procedure. In addition, such bonding increases the torque resistance of the guide wire catheter (12) and pusher element (16) to reduce overall twisting at the distal end of the introducer assembly (10).
摘要翻译：导引器组件（10）包括导丝导管（12），推动元件（16），外部操纵单元（28）和外护套（30）。推动器元件（16）的远端（18）用粘合剂或其它粘合剂（32）与导丝导管（12）接合，以便将这些部件固定在一起的远端（18）处推动元件（16）。这减少了推动器元件（16）相对于导丝导管（12）的扭转，从而扭转承载在导引器组件（10）上的任何可植入医疗装置。这可以减少可植入医疗装置的不正确部署并减少堕胎医疗过程的实例。此外，这种接合增加了导丝导管（12）和推动元件（16）的扭矩阻力，以减小导引器组件（10）的远端处的整体扭转。

3. 发明申请

WO2011019546A1 IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：可植入医疗器械
公开(公告)号：WO2011019546A1
公开(公告)日：2011-02-17
申请号：PCT/US2010/044244
申请日：2010-08-03
申请人： WILLIAM COOK EUROPE APS , COOK INCORPORATED , RASMUSSEN, Erik , OEHLENSCHLAEGER, Bent , JENSEN, Kim, Moegelvang , PETERSEN, Jesper, Schade
发明人： RASMUSSEN, Erik , OEHLENSCHLAEGER, Bent , JENSEN, Kim, Moegelvang , PETERSEN, Jesper, Schade
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/844 , A61F2/86 , A61F2/89 , A61F2/90 , A61F2002/075 , A61F2002/8483 , A61F2210/0014 , A61F2220/0058 , A61F2220/0075 , A61F2310/00023
摘要： A stent graft (10) includes a tubular graft element (12) to which there are attached a plurality of stent rings (14). The stent rings (14) are formed of a plurality of stent struts (16) arranged in a zig-zag arrangement with alternating peaks (18) and valleys (20). The end-most stent (22) is located at the proximal end (24) of the graft tube (12). Between adjacent peaks (18) of the end-most stent (22), there is provided a series of bridging elements (28). These are preferably formed of Nitinol wire and to be substantially more flexible than the stent struts (14). The bridging elements (28) extend in the region of graft material between adjacent stent peaks (18) and are attached to the graft material, for example by suturing. The bridging elements (28) are substantially more flexible than the stent ring (22) and therefore impart little opening force on the graft material in comparison to the force produced by the stent ring (22). However, the bridging elements (28) impart enough force on the flaps (26) of graft material between the peaks (18) of the stent ring (28) keep these flaps (26) open, that is against the vessel wall. The bridging elements (28) can provide integral barbs (30).
摘要翻译：支架移植物（10）包括管状移植物元件（12），其上附接有多个支架环（14）。支架环（14）由布置成具有交替的峰（18）和谷（20）的之字形布置的多个支架支柱（16）形成。最终的支架（22）位于移植管（12）的近端（24）处。在最终支架（22）的相邻峰（18）之间，提供一系列桥接元件（28）。这些优选由镍钛诺丝形成，并且比支架支柱（14）基本上更具柔性。桥接元件（28）在相邻支架顶部（18）之间的移植材料区域中延伸并且例如通过缝合附接到移植物材料。桥接元件（28）比支架环（22）大得多的柔性，因此与支架环（22）产生的力相比，在接枝材料上施加很小的打开力。然而，桥接元件（28）在支架环（28）的峰（18）之间的移植材料的翼片（26）上赋予足够的力，使得这些翼片（26）打开，即抵靠血管壁。桥接元件（28）可以提供整体倒钩（30）。

4. 发明申请

WO2010129685A1 STENT GRAFT 审中-公开
公开(公告)号：WO2010129685A1
公开(公告)日：2010-11-11
申请号：PCT/US2010/033745
申请日：2010-05-05
申请人： WILLIAM COOK EUROPE APS , COOK INCORPORATED , MOERK, Tina , PETERSEN, Jesper, Schade , SOERENSEN, Marianne
发明人： MOERK, Tina , PETERSEN, Jesper, Schade , SOERENSEN, Marianne
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/966 , A61F2002/075 , A61F2230/0013 , A61F2230/005 , A61F2230/0054
摘要： A stent graft (30) has a bare end stent (31) which partially overlaps the next stent (32) with the end (36) of the graft material (34) being shaped to follow the distal peaks (35) of the end stent and the proximal peaks (47) of the next stent. The proximal peaks (37) of the end stent have a greater radius of curvature than the distal peaks (35) of the end stent.
摘要翻译：支架移植物（30）具有与接下来的支架（32）部分重叠的裸端支架（31），其中移植材料（34）的端部（36）被成形为跟随终端支架的远端（35）和下一个支架的近端峰（47）。末端支架的近端峰（37）具有比端支架的远端（35）更大的曲率半径。

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