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1. 发明申请

WO2003008440A2 NUCLEIC ACID MOLECULES ENCODING PROTEINS ESSENTIAL FOR PLANT GROWTH AND DEVELOPMENT AND USES THEREOF 审中-公开
标题翻译：核酸分子编码蛋白质对植物生长和发育的重要性及其用途
公开(公告)号：WO2003008440A2
公开(公告)日：2003-01-30
申请号：PCT/EP2002/007929
申请日：2002-07-16
申请人： SYNGENTA PARTICIPATIONS AG , LEVIN, Joshua, Zvi , PATTON, David, Andrew , MCELVER, John, Alan , BUDZISZEWSKI, Gregory, Joseph , ZHOU, Qing , AUX, George, W. , TOSSBERG, John , WEGRICH GLOVER, Lyn , ASHBY, Carl, Sandidge , THOMAS, Carl, Randall , MADHAVEN, Ernie , LEWIS, Sharon , DUNN, Jill , CATES, Eddie , LAW, Marcus, Dixon
发明人： LEVIN, Joshua, Zvi , PATTON, David, Andrew , MCELVER, John, Alan , BUDZISZEWSKI, Gregory, Joseph , ZHOU, Qing , AUX, George, W. , TOSSBERG, John , WEGRICH GLOVER, Lyn , ASHBY, Carl, Sandidge , THOMAS, Carl, Randall , MADHAVEN, Ernie , LEWIS, Sharon , DUNN, Jill , CATES, Eddie , LAW, Marcus, Dixon
IPC分类号： C07K14/00
CPC分类号： G01N33/5097 , C07K14/415 , C12N9/00 , G01N2333/415 , G01N2500/04
摘要： Nucleotide sequences are isolated from Arabidopsis thaliana that code for proteins essential for plant growth and developement. The essentially of the proteins may be exploited by recombinantly expressing the proteins and using them in screening assays to identify compounds that interact with or inhibit the proteins and are therefore potential herbicides.
摘要翻译：从拟南芥中分离出核苷酸序列，其编码植物生长和发育必需的蛋白质。可以通过重组表达蛋白质来开发基本上的蛋白质，并且在筛选测定中使用它们来鉴定与蛋白质相互作用或抑制蛋白质并因此是潜在的除草剂的化合物。

2. 发明申请

WO9617944A3 ENHANCED BIOTIN BIOSYNTHESIS IN PLANT TISSUE ENHANCED BIOTIN BIOSYNTHESIS IN PLANT TISSUE 审中-公开
标题翻译：植物组织中增强生物素生物素在植物组织中增强生物素生物
公开(公告)号：WO9617944A3
公开(公告)日：1996-08-29
申请号：PCT/EP9504659
申请日：1995-11-27
申请人： CIBA GEIGY AG , PATTON DAVID ANDREW
发明人： PATTON DAVID ANDREW
IPC分类号： A01H5/00 , C12N5/00 , C12N5/10 , C12N9/00 , C12N9/10 , C12N15/09 , C12N15/52 , C12N15/82 , C12R1/91 , C12N5/04
CPC分类号： C12N15/8243 , C12N9/00 , C12N9/1096 , C12N15/52
摘要： The present invention reveals that biotin biosynthesis in a plant is enhanced when the level of one or more of the enzymes in the plant biotin biosynthetic pathway is increased. Based upon this revelation methods which increase the level of one or more biotin biosynthetic enzymes in plant tissue are provided as a means for achieving enhanced levels of biotin in plant tissue. In particular, a method for enhancing biotin levels by introducing a chimeric gene capable of expressing a biotin biosynthetic enzyme into plant tissue is provided. Resulting transgenic plant tissue, including whole plants, having enhanced levels of biotin are also provided.

3. 发明申请

WO2003008440A3 NUCLEIC ACID MOLECULES ENCODING PROTEINS ESSENTIAL FOR PLANT GROWTH 审中-公开
公开(公告)号：WO2003008440A3
公开(公告)日：2003-01-30
申请号：PCT/EP2002/007929
申请日：2002-07-16
申请人： SYNGENTA PARTICIPATIONS AG , LEVIN, Joshua, Zvi , PATTON, David, Andrew , MCELVER, John, Alan , BUDZISZEWSKI, Gregory, Joseph , ZHOU, Qing , AUX, George, W. , TOSSBERG, John , WEGRICH GLOVER, Lyn , ASHBY, Carl, Sandidge , THOMAS, Carl, Randall , MADHAVEN, Ernie , LEWIS, Sharon , DUNN, Jill , CATES, Eddie , LAW, Marcus, Dixon
发明人： LEVIN, Joshua, Zvi , PATTON, David, Andrew , MCELVER, John, Alan , BUDZISZEWSKI, Gregory, Joseph , ZHOU, Qing , AUX, George, W. , TOSSBERG, John , WEGRICH GLOVER, Lyn , ASHBY, Carl, Sandidge , THOMAS, Carl, Randall , MADHAVEN, Ernie , LEWIS, Sharon , DUNN, Jill , CATES, Eddie , LAW, Marcus, Dixon
IPC分类号： G01N33/68
摘要： Nucleotide sequences are isolated from Arabidopsis thaliana that code for proteins essential for plant growth and developement. The essentially of the proteins may be exploited by recombinantly expressing the proteins and using them in screening assays to identify compounds that interact with or inhibit the proteins and are therefore potential herbicides.

4. 发明申请

WO0200696A3 HERBICIDE TARGET GENES AND METHODS 审中-公开
标题翻译：除草剂目标基因和方法
公开(公告)号：WO0200696A3
公开(公告)日：2003-01-09
申请号：PCT/EP0107252
申请日：2001-06-26
申请人： SYNGENTA PARTICIPATIONS AG , PATTON DAVID ANDREW , ASHBY CARL SANDIDGE , VOLRATH SANDRA LYNN , MCELVER JOHN ALAN , BAUER MICHAEL WILLIAM
发明人： PATTON DAVID ANDREW , ASHBY CARL SANDIDGE , VOLRATH SANDRA LYNN , MCELVER JOHN ALAN , BAUER MICHAEL WILLIAM
IPC分类号： C12N9/00 , C12N9/12 , C12N15/54 , C12N15/82 , C12N15/52 , A01H5/00 , A01H5/10 , C12N5/10 , G01N33/573
CPC分类号： C12N9/93 , C12N9/12 , C12N9/1205 , C12N15/8274 , G01N2430/20 , G01N2500/00
摘要： The invention relates to genes isolated from Arabidopsis that code for proteins essential for normal plant development. The invention also includes the methods of using these proteins to discover new herbicides, based on the essentiality of the genes for normal growth and development. The invention can also be used in a screening assay to identify inhibitors that are potential herbicides. The invention is also applied to the development of herbicide tolerant plants, plant tissues, plant seeds, and plant cells.
摘要翻译：本发明涉及从拟南芥中分离的编码对正常植物发育必需的蛋白质的基因。本发明还包括基于正常生长和发育的基因的本质来使用这些蛋白质发现新的除草剂的方法。本发明还可用于筛选测定以鉴定潜在除草剂的抑制剂。本发明还适用于除草剂耐受性植物，植物组织，植物种子和植物细胞的开发。

5. 发明申请

WO0078799A3 MLO-GENES CONTROLLING DISEASES 审中-公开
标题翻译： MLO基因控制疾病
公开(公告)号：WO0078799A3
公开(公告)日：2001-07-26
申请号：PCT/EP0005576
申请日：2000-06-16
申请人： SYNGENTA PARTICIPATIONS AG , SALMERON JOHN MANUEL , WEISLO LAURA JEAN , STRAWN LESLIE JEAN , KRAMER CATHERINE MAE , WANG HELEN XIAOHUI , VERNOOIJ BERNARDUS THEODORUS , LEVIN JOSHUA ZVI , HEIFETZ PETER BERNARD , PATTON DAVID ANDREW , QUE QIUDENG
发明人： SALMERON JOHN MANUEL , WEISLO LAURA JEAN , STRAWN LESLIE JEAN , KRAMER CATHERINE MAE , WANG HELEN XIAOHUI , VERNOOIJ BERNARDUS THEODORUS , LEVIN JOSHUA ZVI , HEIFETZ PETER BERNARD , PATTON DAVID ANDREW , QUE QIUDENG
IPC分类号： C07K14/415 , C12N15/82 , A01H5/00 , C12N5/10 , C12N15/29 , C12Q1/68
CPC分类号： C12N15/8282 , C07K14/415
摘要： This invention describes genes encoding proteins which control resistance of plants to fungal pathogens. The invention also describes transgenic plants resistant to fungal pathogens and methods for making plants resistant to fungal pathogens. The invention further discloses a method to isolate additional genes coding for additional proteins controlling the resistance of plants to fungal pathogens.
摘要翻译：本发明描述了编码控制植物对真菌病原体的抗性的蛋白质的基因。本发明还描述了对真菌病原体有抗性的转基因植物和用于使植物对真菌病原体有抗性的方法。本发明进一步公开了一种方法，用于分离编码另外的控制植物对真菌病原体的抗性的另外的蛋白质的基因。

6. 发明申请

WO03074653A2 NUCLEIC ACID MOLECULES ENCODING PROTEINS ESSENTIAL FOR PLANT GROWTH AND DEVELOPMENT AND USES THEREOF 审中-公开
标题翻译：核酸分子编码蛋白质对植物生长和发育的重要性及其用途
公开(公告)号：WO03074653A2
公开(公告)日：2003-09-12
申请号：PCT/US0304787
申请日：2003-02-14
申请人： SYNGENTA PARTICIPATIONS AG , LEVIN JOSHUA Z , PATTON DAVID ANDREW , MCELVER JOHN ALAN , ZHOU QING , AUX GEORGE W , TOSSBERG JOHN , ASHBY CARL , DUNN JILL , CATES EDDIE , LAW MARCUS DIXON , BUDZISZEWSKI GREGORY W , NYFELER BEAT , WU JIAQIAN , YATES MICHAEL , WARREN GREGORY W , STULTS LARRY , VRANA BRUCE , MORTON MARCIA , SCHWARTZ RANDEE , LEBEL EDOUARD GUILLAUME
发明人： LEVIN JOSHUA Z , PATTON DAVID ANDREW , MCELVER JOHN ALAN , ZHOU QING , AUX GEORGE W , TOSSBERG JOHN , ASHBY CARL , DUNN JILL , CATES EDDIE , LAW MARCUS DIXON , BUDZISZEWSKI GREGORY W , NYFELER BEAT , WU JIAQIAN , YATES MICHAEL , WARREN GREGORY W , STULTS LARRY , VRANA BRUCE , MORTON MARCIA , SCHWARTZ RANDEE , LEBEL EDOUARD GUILLAUME
IPC分类号： C07K14/415 , C12N
CPC分类号： C07K14/415
摘要： Nucleotide sequences are isolated from Arabiodpsis thaliana that code for proteins essential for plant growth and development. The essentially of the proteins may be exploited by recombinantly expressing the proteins and using them in screening assays to identify compounds that interact with or inhibit the proteins and are therefore potential herbicides.
摘要翻译：从拟南芥中分离出核苷酸序列，其编码植物生长和发育必需的蛋白质。可以通过重组表达蛋白质来开发基本上的蛋白质，并且在筛选测定中使用它们来鉴定与蛋白质相互作用或抑制蛋白质并因此是潜在的除草剂的化合物。

7. 发明申请

WO2003074653A3 NUCLEIC ACID MOLECULES ENCODING PROTEINS ESSENTIAL FOR PLANT GROWTH AND DEVELOPMENT AND USES THEREOF 审中-公开
公开(公告)号：WO2003074653A3
公开(公告)日：2003-09-12
申请号：PCT/US2003/004787
申请日：2003-02-14
申请人： SYNGENTA PARTICIPATIONS AG , LEVIN, Joshua, Z. , PATTON, DAVID, Andrew , MCELVER, John, Alan , ZHOU, Qing , AUX, George, W. , TOSSBERG, John , ASHBY, Carl , DUNN, Jill , CATES, Eddie , LAW, Marcus, Dixon , BUDZISZEWSKI, Gregory, W. , NYFELER, Beat , WU, Jiaqian , YATES, Michael , WARREN, Gregory, W. , STULTS, Larry , VRANA, Bruce , MORTON, Marcia , SCHWARTZ, Randee , LEBEL, Edouard, Guillaume
发明人： LEVIN, Joshua, Z. , PATTON, DAVID, Andrew , MCELVER, John, Alan , ZHOU, Qing , AUX, George, W. , TOSSBERG, John , ASHBY, Carl , DUNN, Jill , CATES, Eddie , LAW, Marcus, Dixon , BUDZISZEWSKI, Gregory, W. , NYFELER, Beat , WU, Jiaqian , YATES, Michael , WARREN, Gregory, W. , STULTS, Larry , VRANA, Bruce , MORTON, Marcia , SCHWARTZ, Randee , LEBEL, Edouard, Guillaume
IPC分类号： C12Q1/37
摘要： Nucleotide sequences are isolated from Arabidopsis thaliana that code for proteins essential for plant growth and development. The essential proteins may be exploited by recombinantly expressing the proteins and using them in screening assays to identify compounds that interact with or inhibit the proteins and are therefore potential herbicides.

8. 发明申请

WO0053782A3 HERBICIDE TARGET GENES AND METHODS 审中-公开
标题翻译：除草剂目标基因和方法
公开(公告)号：WO0053782A3
公开(公告)日：2000-12-21
申请号：PCT/EP0001884
申请日：2000-03-03
申请人： NOVARTIS AG , NOVARTIS ERFIND VERWALT GMBH , PATTON DAVID ANDREW , ASHBY CARL SANDIDGE , THOMAS CARLA RANDALL , MCELVER JOHN ALAN , LEVIN JOSHUA ZVI , BUDZISZEWSKI GREGORY JOSEPH
发明人： PATTON DAVID ANDREW , ASHBY CARL SANDIDGE , THOMAS CARLA RANDALL , MCELVER JOHN ALAN , LEVIN JOSHUA ZVI , BUDZISZEWSKI GREGORY JOSEPH
IPC分类号： C07K14/415 , C12N9/10 , C12N9/14 , C12N9/90 , C12N15/29 , C12N15/54 , C12N15/55 , C12N15/61 , C12N15/82
CPC分类号： C12N9/1029 , C07K14/415 , C12N9/14 , C12N9/90 , C12N15/8274
摘要： The invention relates to genes isolated from Arabidopsis that code for proteins essential for normal plant development. The invention also includes the methods of using these proteins to discover new herbicides, based on the essentiality of the genes for normal growth and development. The invention can also be used in a screening assay to identify inhibitors that are potential herbicides. The invention is also applied to the development of herbicide tolerant plants, plant tissues, plant seeds, and plant cells.
摘要翻译：本发明涉及从拟南芥分离的基因，其编码正常植物发育必需的蛋白质。本发明还包括基于正常生长和发育的基因的本质来使用这些蛋白质发现新的除草剂的方法。本发明还可用于筛选测定以鉴定潜在除草剂的抑制剂。本发明还适用于除草剂耐受性植物，植物组织，植物种子和植物细胞的开发。

9. 发明申请

WO1996017944A2 ENHANCED BIOTIN BIOSYNTHESIS IN PLANT TISSUE 审中-公开
标题翻译：植物组织中增强生物素生物素
公开(公告)号：WO1996017944A2
公开(公告)日：1996-06-13
申请号：PCT/EP1995004659
申请日：1995-11-27
申请人： CIBA-GEIGY AG , PATTON, David, Andrew
发明人： CIBA-GEIGY AG
IPC分类号： C12N15/82
CPC分类号： C12N15/8243 , C12N9/00 , C12N9/1096 , C12N15/52
摘要： The present invention reveals that biotin biosynthesis in a plant is enhanced when the level of one or more of the enzymes in the plant biotin biosynthetic pathway is increased. Based upon this revelation methods which increase the level of one or more biotin biosynthetic enzymes in plant tissue are provided as a means for achieving enhanced levels of biotin in plant tissue. In particular, a method for enhancing biotin levels by introducing a chimeric gene capable of expressing a biotin biosynthetic enzyme into plant tissue is provided. Resulting transgenic plant tissue, including whole plants, having enhanced levels of biotin are also provided.
摘要翻译：本发明揭示当植物生物素生物合成途径中的一种或多种酶的水平增加时，植物中的生物素生物合成增强。基于提高植物组织中一种或多种生物素生物合成酶水平的这种启示方法，作为在植物组织中达到提高生物素水平的手段。特别地，提供了通过将能够表达生物素生物合成酶的嵌合基因导入植物组织来提高生物素水平的方法。还提供了具有增强的生物素水平的所得转基因植物组织，包括整株植物。

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