专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2012156981A1 PHARMACEUTICAL COMPOSITIONS OF LURASIDONE 审中-公开
标题翻译： LURASIDONE的药物组合物
公开(公告)号：WO2012156981A1
公开(公告)日：2012-11-22
申请号：PCT/IN2012/000015
申请日：2012-01-05
申请人： CADILA HEALTHCARE LIMITED , KHERA, Brij , TREHAN, Aman , PATEL, Pankaj Ramanbhai
发明人： KHERA, Brij , TREHAN, Aman , PATEL, Pankaj Ramanbhai
IPC分类号： A61K9/16 , A61K9/20 , A61K31/496
CPC分类号： A61K31/496 , A61K9/1635 , A61K9/1652 , A61K9/2009 , A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/2077
摘要： The present invention relates to pharmaceutical compositions of lurasidone or salts thereof. In particular, the invention relates to pharmaceutical compositions of lurasidone or salts thereof with one or more water-insoluble pharmaceutical excipients. The invention also relates to processes for the preparation of such compositions and use thereof for treatment of schizophrenia, bipolar disorders or senile dementia.
摘要翻译：本发明涉及卢拉西酮或其盐的药物组合物。特别地，本发明涉及卢拉西酮或其盐与一种或多种水不溶性药物赋形剂的药物组合物。本发明还涉及制备这种组合物的方法及其用于治疗精神分裂症，双相性精神障碍或老年痴呆症的用途。

2. 发明申请

WO2011060422A2 VALVE SEAT INSTALLATION AND RETRIEVAL TOOL 审中-公开
标题翻译：阀座安装和检索工具
公开(公告)号：WO2011060422A2
公开(公告)日：2011-05-19
申请号：PCT/US2010/056846
申请日：2010-11-16
申请人： WEIR SPM, INC. , PATEL, Pankaj, H.
发明人： PATEL, Pankaj, H.
CPC分类号： F04B53/1087 , Y10T29/49407 , Y10T29/53596
摘要： A tool for replacing a valve seat of a reciprocating pump has a puller shaft connected to a puller head having at least two spring-biased dogs. An operator inserts the puller head into a valve bore and through a valve seat, the dogs retracting as the puller head moves through the valve seat, then snapping back outward. A hydraulic cylinder engages the puller shaft to exert a force on the puller shaft causing the dogs to dislodge the seat. The operator then places a replacement valve seat on a shoulder in the valve bore. The operator attaches an installing head to an installing shaft and inserts the installing head into the valve bore into contact with the replacement valve seat. The hydraulic cylinder applies a force in an opposite direction on the installing shaft to push the replacement valve seat into installed engagement.
摘要翻译：用于更换往复泵的阀座的工具具有连接到具有至少两个弹簧偏置卡爪的牵引头的牵引轴。操作人员将拉头插入阀孔并通过阀座，当牵引头移动通过阀座时，卡爪将收回，然后向外弹回。液压缸与牵引杆接合以在拉杆轴上施加力，导致狗移开座椅。然后操作人员将更换的阀座放置在阀孔的肩部上。操作人员将安装头安装到安装轴上，并将安装头插入阀孔与更换阀座接触。液压缸在安装轴上以相反的方向施加力，以将替换阀座推入安装接合。

3. 发明申请

WO2011008763A2 THREADED ROD PLUNGER INSTALLATION TOOL 审中-公开
标题翻译：螺纹杆式安装工具
公开(公告)号：WO2011008763A2
公开(公告)日：2011-01-20
申请号：PCT/US2010/041832
申请日：2010-07-13
申请人： WEIR SPM, INC. , PATEL, Pankaj
发明人： PATEL, Pankaj
IPC分类号： F04B53/00 , F04B53/22 , F04B39/00 , F04B47/00 , F04B17/00
CPC分类号： F04B23/00 , F04B53/22 , Y10T29/49229 , Y10T29/49231 , Y10T29/49236 , Y10T29/49826 , Y10T29/53 , Y10T29/53848 , Y10T29/53891 , Y10T29/53952
摘要： A plunger installation tool that exerts a force on a plunger for a reciprocating pump to install the plunger into a pump cylinder opening. Maintenance of the pump typically includes repacking of the packing that surrounds the plunger and revalving of the pump's inlet and outlet valve. To allow repacking or revalving, the pump is disassembled and the plunger is removed. The plunger installation tool threads onto the pump cylinder opening to provide a reaction point for a threaded rod that is driven at one end by a driver and engages the plunger at an opposite end during installation to push the plunger into the cylinder opening without the use of hammers by personnel.
摘要翻译：
柱塞安装工具，其对往复泵的柱塞施加力以将柱塞安装到泵缸开口中。泵的维护通常包括重新包装柱塞周围的填料并重新调整泵的入口和出口阀。为了允许重新包装或重新调整，泵被拆卸并且柱塞被移除。柱塞安装工具螺纹连接到泵筒开口上，以为螺杆提供反作用点，螺杆在一端由驱动器驱动并且在安装期间在相对端接合柱塞以将柱塞推入缸开口而不使用由人员敲击。

4. 发明申请

WO2009125424A3 PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC ACTIVITIES 审中-公开
公开(公告)号：WO2009125424A3
公开(公告)日：2009-10-15
申请号：PCT/IN2008/000831
申请日：2008-12-10
申请人： CADILA HEALTHCARE LIMITED , BAHEKAR, Rajesh, H. , JAIN, Mukul, R , PATEL, Pankaj, Ramanbhai
发明人： BAHEKAR, Rajesh, H. , JAIN, Mukul, R , PATEL, Pankaj, Ramanbhai
IPC分类号： C07K14/605 , A61K38/26
摘要： The present invention provides novel peptidomimetics, of formula (I), which primarily act as glucose dependent insulin secretagogues. Furthermore, it was found that these peptidomimetics showed glucagon receptor antagonistic activity, along with the GLP-I receptor agonistic activity.

5. 发明申请

WO2009125424A2 PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC ACTIVITIES 审中-公开
标题翻译：具有GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC活动的肽酶
公开(公告)号：WO2009125424A2
公开(公告)日：2009-10-15
申请号：PCT/IN2008000831
申请日：2008-12-10
申请人： CADILA HEALTHCARE LTD , BAHEKAR RAJESH H , JAIN MUKUL R , PATEL PANKAJ RAMANBHAI
发明人： BAHEKAR RAJESH H , JAIN MUKUL R , PATEL PANKAJ RAMANBHAI
IPC分类号： C07K14/605 , A61K38/26
CPC分类号： C07K14/605 , A61K38/00
摘要： The present invention provides novel peptidomimetics, of formula (I), which primarily act as glucose dependent insulin secretagogues. Furthermore, it was found that these peptidomimetics showed glucagon receptor antagonistic activity, along with the GLP-I receptor agonistic activity.
摘要翻译：本发明提供式（I）的新型肽模拟物，其主要作为葡萄糖依赖性胰岛素促分泌剂。此外，发现这些肽模拟物显示胰高血糖素受体拮抗活性，以及GLP-1受体激动活性。

6. 发明申请

WO2009063495A3 SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS 审中-公开
标题翻译：取代的吲哚及其衍生物作为甘油调节剂
公开(公告)号：WO2009063495A3
公开(公告)日：2009-08-06
申请号：PCT/IN2008000582
申请日：2008-09-11
申请人： CADILA HEALTHCARE LTD , SRIVASTAVA BRIJESH KUMAR , PATEL PANKAJ RAMANBHAI
发明人： SRIVASTAVA BRIJESH KUMAR , PATEL PANKAJ RAMANBHAI
IPC分类号： C07D209/12 , A61K31/404 , A61P29/00 , C07D209/32
CPC分类号： C07D209/12 , C07D209/32
摘要： The present invention relates to novel substituted indole and indole derivatives to pharmaceutical compositions comprising the same, and to uses thereof. Compounds of the invention share pharmacological properties with cannabinoids and have a common wide range of beneficial therapeutic indications, hi particular, compounds of the invention are useful analgesic and anti-inflammatory agents by modulating the CB2 receptor.
摘要翻译：本发明涉及新颖的取代的吲哚和吲哚衍生物用于包含它们的药物组合物及其应用。本发明的化合物与大麻素具有共同的药理学性质，并且具有普遍的广泛的有益的治疗适应症。特别地，本发明的化合物是通过调节CB2受体是有用的止痛剂和抗炎剂。

7. 发明申请

WO2009053999A3 SULFOXIMINE DERIVATIVES AS FACTOR XA INHIBITORS 审中-公开
标题翻译： SULFOXIMINE DERIVATIVES作为因子XA抑制剂
公开(公告)号：WO2009053999A3
公开(公告)日：2009-08-06
申请号：PCT/IN2008000483
申请日：2008-08-04
申请人： CADILA HEALTHCARE LTD , PANDYA VRAJESH B , PATEL PANKAJ RAMANBHAI
发明人： PANDYA VRAJESH B , PATEL PANKAJ RAMANBHAI
IPC分类号： C07D213/75 , A61K31/44 , A61P7/02 , C07D213/81 , C07D401/12
CPC分类号： C07D213/75 , C07D213/81 , C07D401/12
摘要： The present invention relates to novel substituted sulfoximine derivatives of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation.
摘要翻译：本发明涉及通式（I）的新型取代的亚磺酰亚胺衍生物，其互变异构形式，其立体异构体，其药学上可接受的盐，含有它们的药物组合物，其制备方法，这些化合物在医药中的用途以及涉及他们的准备。

8. 发明申请

WO2009087664A1 PROCESS FOR PREPARING CHEMICALLY AND CHIRALLY PURE SOLIFENACIN BASE AND ITS SALTS 审中-公开
标题翻译：化学和精制固体碱基及其盐的制备方法
公开(公告)号：WO2009087664A1
公开(公告)日：2009-07-16
申请号：PCT/IN2008/000797
申请日：2008-12-02
申请人： CADILA HEALTHCARE LIMITED , DAVE, Mayank, Ghanshyambhai , PANDEY, Bipin , KOTHARI, Himanshu, M. , PATEL, Pankaj, Ramanbhai
发明人： DAVE, Mayank, Ghanshyambhai , PANDEY, Bipin , KOTHARI, Himanshu, M. , PATEL, Pankaj, Ramanbhai
IPC分类号： C07D453/02 , A61K31/439 , A61P13/10
CPC分类号： C07D453/02
摘要： The present invention provides improved processes for preparing chemically and chirally pure Solifenacin base. The present invention also provides for a composition comprising of a salt of Solifenacin having at least 98 % purity. The present invention also disclose certain new salts of Solifenacin as well as well as new polymorphic forms of Solifenacin hydrochloride and Solifenacin oxalate, in pure form.
摘要翻译：本发明提供了用于制备化学和手性纯的索赖那新碱的改进方法。本发明还提供了包含至少98％纯度的索非那新盐的组合物。本发明还公开了Solifenacin的某些新盐以及纯的形式的盐酸索非那新和草苯甲酸索非那新的新多晶型物。

9. 发明申请

WO2009087649A1 RENIN INHIBITORS 审中-公开
标题翻译：雷宁抑制剂
公开(公告)号：WO2009087649A1
公开(公告)日：2009-07-16
申请号：PCT/IN2008/000662
申请日：2008-10-13
申请人： CADILA HEALTHCARE LIMITED , DESAI, Jigar , THOMBARE, Pravin, S. , JAIN, Mukul, R. , PATEL, Pankaj, Ramanbhai
发明人： DESAI, Jigar , THOMBARE, Pravin, S. , JAIN, Mukul, R. , PATEL, Pankaj, Ramanbhai
IPC分类号： C07D207/14 , C07D207/16 , C07D209/08 , C07D211/16 , C07D211/22 , C07D213/64 , C07D215/08 , C07D215/12 , C07D215/14 , C07D215/18 , C07D215/20 , C07D215/26 , C07D217/06 , C07D265/36 , C07D401/06 , C07D403/04 , C07D295/185 , A61K31/4709 , A61P9/00
CPC分类号： C07D215/08 , C07D207/14 , C07D207/16 , C07D209/08 , C07D211/16 , C07D211/22 , C07D213/64 , C07D215/12 , C07D215/14 , C07D215/18 , C07D215/20 , C07D215/26 , C07D217/06 , C07D265/36 , C07D295/185 , C07D401/06 , C07D403/04
摘要： The present invention relates to novel renin inhibitors of general formula (1), novel intermediates involved in their synthesis, their pharmaceutically acceptable salts and pharmaceutical compositions containing them. The present invention also relates to a process of preparing compounds of general formula (1), their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis.
摘要翻译：本发明涉及通式（1）的新型肾素抑制剂，涉及其合成的新中间体，其药学上可接受的盐和含有它们的药物组合物。本发明还涉及制备通式（1）的化合物，其互变异构形式，其药学上可接受的盐，含有它们的药物组合物和参与其合成的新中间体的方法。

10. 发明申请

WO2009066320A2 FUSION PROTEIN SYSTEMS SUITABLE FOR HIGH EXPRESSION OF PEPTIDES 审中-公开
标题翻译：用于表达高表达的融合蛋白质系统
公开(公告)号：WO2009066320A2
公开(公告)日：2009-05-28
申请号：PCT/IN2008/000599
申请日：2008-09-22
申请人： CADILA HEALTHCARE LIMITED , MENDIRETTA, Sanjeev, Kumar , PATEL, Pankaj, R. , BANDYOPADHYAY, Sanjay , SARASWAT, Vibhor , SINGH, Arun, Kumar
发明人： MENDIRETTA, Sanjeev, Kumar , PATEL, Pankaj, R. , BANDYOPADHYAY, Sanjay , SARASWAT, Vibhor , SINGH, Arun, Kumar
IPC分类号： C07K14/435
CPC分类号： C12N15/62 , C07K14/535 , C07K14/62 , C07K14/635 , C12P21/02
摘要： The present invention discloses an improved process for the production of desired recombinant peptides from bacterial cells by using G-CSF as a novel fusion partner for their high level expression in these cells. The invention further provides an expression system comprising the fusion protein wherein the G-CSF is operatively linked to the peptide of interest via an enzymatic or chemical cleavage site which can be used to separate the fusion partner from the said peptide.
摘要翻译：本发明公开了通过使用G-CSF作为这些细胞中高水平表达的新型融合配偶体从细菌细胞中产生所需重组肽的改进方法。本发明还提供了包含融合蛋白的表达系统，其中G-CSF通过酶或化学切割位点可操作地连接到目的肽，其可用于从融合配偶体与所述肽分离。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式