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1. 发明申请

WO2002085832A2 SOLID MIXTURES OF ALPHA-HYDROXYCARBONYL DERIVATIVES OF ALPHA-METHYLSTYRENE OLIGOMERS AND THEIR USE 审中-公开
标题翻译： ALPHA-甲基苯乙烯低聚物的ALPHA-羟基羰基衍生物及其用途的固体混合物
公开(公告)号：WO2002085832A2
公开(公告)日：2002-10-31
申请号：PCT/EP2002/003674
申请日：2002-04-03
申请人： LAMBERTI SPA , VISCONTI, Marco , NORCINI, Gabriele , LI BASSI, Giuseppe
发明人： VISCONTI, Marco , NORCINI, Gabriele , LI BASSI, Giuseppe
IPC分类号： C07C49/83
CPC分类号： G03F7/031 , C07C45/81 , C07C49/83 , C08F2/50 , C08F6/12
摘要： The present invention refers to solid mixtures of alpha hydroxycarbonyl derivatives of alpha-methylstyrene oligomers containing at least 90 % of the dimer isomers, the dimer isomer ratio being between 2.5 and 7, to their preparation and to their use as photoinitiators in photopolymerisation.
摘要翻译：本发明涉及α-甲基苯乙烯低聚物的α-羟基羰基衍生物的固体混合物，它们含有至少90％的二聚体异构体，二聚体异构体比例在2.5和7之间，与它们的制备和在光聚合反应中作为光引发剂的用途。

2. 发明申请

WO1997024341A1 THIOL DERIVATIVES WITH METALLOPEPTIDASE (ACE/NEP) INHIBITORY ACTIVITY 审中-公开
标题翻译：具有金属蛋白酶（ACE / NEP）抑制活性的THIOL衍生物
公开(公告)号：WO1997024341A1
公开(公告)日：1997-07-10
申请号：PCT/EP1996005496
申请日：1996-12-09
申请人： ZAMBON GROUP S.P.A. , PELLACINI, Franco , ROMAGNANO, Stefano , NORCINI, Gabriele , SANTANGELO, Francesco , SEMERARO, Claudio
发明人： ZAMBON GROUP S.P.A.
IPC分类号： C07D275/02
CPC分类号： C07D333/24 , C07D213/55 , C07D277/30
摘要： Compounds of formula (I) wherein R, R1, R2, R3 have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described. The compounds of formula (I) are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.
摘要翻译：描述了其中R，R 1，R 2，R 3具有本说明书中报道的含义，其制备方法和含有它们作为活性成分的药物组合物的式（I）化合物。式（I）化合物具有混合的ACE抑制和NEP抑制活性，可用于治疗心血管疾病。

3. 发明申请

WO1995028417A1 PHOSPHONYLDIPEPTIDES USEFUL IN THE TREATMENT OF CARDIOVASCULAR DISEASES 审中-公开
标题翻译：用于治疗心血管疾病的磷酰胆碱
公开(公告)号：WO1995028417A1
公开(公告)日：1995-10-26
申请号：PCT/EP1995001322
申请日：1995-04-11
申请人： ZAMBON GROUP S.P.A. , NORCINI, Gabriele , MORAZZONI, Gabriele , SANTANGELO, Francesco
发明人： ZAMBON GROUP S.P.A.
IPC分类号： C07K05/06
CPC分类号： C07K5/06191 , A61K38/00
摘要： Compounds of formula (II) wherein R is a biphenyl group optionally substituted by one or more substituents, the same or different, selected among halogen atoms, hydroxy groups, alkoxy, alkyl or thioalkyl groups having from 1 to 6 carbon atoms in the alkyl moiety, carboxylic groups, nitro groups, amino, mono- or di-alkylamino groups having from 1 to 6 carbon atoms in the alkyl moiety; R1 is a hydrogen atom or a straight or branched C1-C4 alkyl; R2 is a straight or branched C1-C6 alkyl or an arylalkyl having from 1 to 6 carbon atoms in the alkyl moiety wherein the aryl is a phenyl, a naphthyl or a 5 or 6 membered aromatic heterocycle with one or two heteroatoms selected among nitrogen, oxygen and sulphur, optionally substituted as above indicated for the R substituent; R3 is a straight or branched C1-C6 alkyl, optionally containing one or more fluorine atoms, or an arylalkyl having from 1 to 6 carbon atoms in the alkyl moiety; the carbon atoms marked with an asterisk are asymmetric carbon atoms; and their pharmaceutically acceptable salts, are described. The compounds of formula (II) are useful in the treatment of cardiovascular diseases.
摘要翻译：式（II）化合物其中R是任选被一个或多个选自在烷基部分中具有1至6个碳原子的卤素原子，羟基，烷氧基，烷基或硫代烷基中的一个或多个相同或不同的取代基取代的联苯基，羧基，硝基，氨基，在烷基部分具有1至6个碳原子的一或二烷基氨基; R1是氢原子或直链或支链C 1 -C 4烷基; R2是直链或支链的C 1 -C 6烷基或在烷基部分具有1至6个碳原子的芳基烷基，其中芳基是苯基，萘基或具有一个或两个选自氮，氧和硫，任选地被如上述R取代基所取代; R3是任选地含有一个或多个氟原子的直链或支链C 1 -C 6烷基或在烷基部分具有1至6个碳原子的芳基烷基; 标有星号的碳原子是不对称碳原子; 及其药学上可接受的盐。式（II）的化合物可用于治疗心血管疾病。

4. 发明申请

WO2010103035A1 PROCESS FOR THE PREPARATION OF CRYSTALLINE MIXTURES OF ALPHA-HYDROXYCARBONYL DERIVATIVES OF ALPHA-METHYLSTYRENE DIMERS 审中-公开
标题翻译：制备ALPHA-甲基苯乙烯二聚体的α-羟基羰基衍生物的晶体混合物的方法
公开(公告)号：WO2010103035A1
公开(公告)日：2010-09-16
申请号：PCT/EP2010/053021
申请日：2010-03-10
申请人： LAMBERTI SPA , LI BASSI, Giuseppe , NORCINI, Gabriele , FEDERICI, Leonardo
发明人： LI BASSI, Giuseppe , NORCINI, Gabriele , FEDERICI, Leonardo
IPC分类号： C07C45/81 , C07C49/83 , C08F2/50 , G03F7/031
CPC分类号： C08F2/50 , C07C45/81 , G03F7/031 , C07C49/82
摘要： Process for the preparation of the powdery crystalline mixtures of alpha-hydroxycarbonyl derivatives of alpha-methylstyrene dinners comprising the use of a solvent having polarity from 0 to 0.1.
摘要翻译：制备α-甲基苯乙烯二甲醚的α-羟基羰基衍生物的粉状结晶混合物的方法，其包括使用极性为0至0.1的溶剂。

5. 发明申请

WO2009037130A1 PHOTOINITIATORS FOR ENERGY CURING 审中-公开
标题翻译：光能固化装置
公开(公告)号：WO2009037130A1
公开(公告)日：2009-03-26
申请号：PCT/EP2008/061726
申请日：2008-09-05
申请人： LAMBERTI SPA , ROMAGNANO, Stefano , NORCINI, Gabriele , LI BASSI, Giuseppe , VISCONTI, Marco , DIETLIN, Celine , ALLONAS, Xavier , FOUASSIER, Jean Pierre
发明人： ROMAGNANO, Stefano , NORCINI, Gabriele , LI BASSI, Giuseppe , VISCONTI, Marco , DIETLIN, Celine , ALLONAS, Xavier , FOUASSIER, Jean Pierre
IPC分类号： C08F2/50
CPC分类号： C08F2/50 , G03F7/031
摘要： Photopolymerisable systems for coatings or photolithography comprising radically photopolimerisable oligomers and/or monomers having ethylenically unsaturated groups and, as photoinitiator, at least one compoundof formula (I).
摘要翻译：包含自由基可光聚合的低聚物和/或具有烯键式不饱和基团的单体和用作光引发剂的至少一种式（I）化合物的用于涂料或光刻的可光聚合体系。

6. 发明申请

WO2005014515A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS 审中-公开
标题翻译：用于制备高厚度涂层的透明可光聚合系统
公开(公告)号：WO2005014515A2
公开(公告)日：2005-02-17
申请号：PCT/EP2004/051699
申请日：2004-08-03
申请人： LAMBERTI SPA , NORCINI, Gabriele , ROMAGNANO, Stefano , VISCONTI, Marco , LI BASSI, Giuseppe
发明人： NORCINI, Gabriele , ROMAGNANO, Stefano , VISCONTI, Marco , LI BASSI, Giuseppe
IPC分类号： C07C49/84
CPC分类号： C07D295/108 , C07C45/46 , C07C45/63 , C07C45/64 , C07C49/84 , C07C225/16 , C07C2601/14 , C08F2/50 , G03F7/031
摘要： The present invention relates to clear photopolymerisable systems for the preparation of high thickness coatings, to a procedure for their application and to the solid surfaces coated with them.
摘要翻译：本发明涉及用于制备高厚度涂层的透明可光聚合体系，涉及它们的应用程序和涂覆它们的固体表面。

7. 发明申请

WO1997019102A1 PHOSPHONIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY 审中-公开
标题翻译：具有金属蛋白酶抑制活性的磷酸衍生物
公开(公告)号：WO1997019102A1
公开(公告)日：1997-05-29
申请号：PCT/EP1996004911
申请日：1996-11-11
申请人： ZAMBON GROUP S.P.A. , NORCINI, Gabriele , BOTTA, Daniela , SANTANGELO, Francesco
发明人： ZAMBON GROUP S.P.A.
IPC分类号： C07K05/062
CPC分类号： C07K5/06191 , A61K38/00 , Y02P20/55
摘要： Compounds of formula (I) wherein R is an alkyl, aryl or arylalkyl group wherein the aryl is phenyl, naphthyl or heterocycle; R1 and R2, the same or different, are hydrogen atoms or alkyl groups; R3 is an aryl or arylalkyl group wherein the aryl is as above; R4 is a heterocycle optionally substituted with a heterocycle or phenyl, or it is a phenyl group substituted with a heterocycle (R4 is not imidazole or indole); X is a bond or -OCONH or -CONH- group, processes for their preparation and pharmaceutical compositions thereof, are described. The compounds of formula (I) are endowed with a dual ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.
摘要翻译：式（I）化合物，其中R是烷基，芳基或芳基烷基，其中芳基是苯基，萘基或杂环; R1和R2相同或不同，是氢原子或烷基; R3是芳基或芳基烷基，其中芳基如上所述; R4是任选被杂环或苯基取代的杂环，或它是被杂环取代的苯基（R4不是咪唑或吲哚）; X是键或-OCONH或-CONH-基，其制备方法及其药物组合物。式（I）化合物具有双重ACE抑制和NEP抑制活性，可用于治疗心血管疾病。

8. 发明申请

WO2008104436A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS 审中-公开
标题翻译：水滑石作为光敏剂
公开(公告)号：WO2008104436A1
公开(公告)日：2008-09-04
申请号：PCT/EP2008/051183
申请日：2008-01-31
申请人： LAMBERTI SPA , CASIRAGHI, Angelo , VISCONTI, Marco , NORCINI, Gabriele , DIETLIN, Céline , ALLONAS, Xavier , FOUASSIER, Jean Pierre , LI BASSI, Giuseppe
发明人： CASIRAGHI, Angelo , VISCONTI, Marco , NORCINI, Gabriele , DIETLIN, Céline , ALLONAS, Xavier , FOUASSIER, Jean Pierre , LI BASSI, Giuseppe
IPC分类号： B41C1/00 , C08F2/48 , G03F7/00
CPC分类号： C08F2/50 , G03F7/031
摘要： The present invention concerns photopolymerisable systems comprising reactive oligomers and/or monomers having ethylenically unsaturated groups and as photoinitiator at least one hydroxamic ester of Formula (I) or (II) or (III).
摘要翻译：本发明涉及包含具有烯属不饱和基团的反应性低聚物和/或单体和作为光引发剂的至少一种式（I）或（II）或（III）的异羟肟酸酯的可光聚合体系。

9. 发明申请

WO03008404A3 SULFONIUM SALTS AS PHTOINITIATORS FOR RADIATION CURABLE SYSTEMS 审中-公开
标题翻译： SULFONIUM SALTS作为辐射可固化系统的试剂
公开(公告)号：WO03008404A3
公开(公告)日：2003-08-28
申请号：PCT/EP0207415
申请日：2002-07-04
申请人： LAMBERTI SPA , NORCINI GABRIELE , CASIRAGHI ANGELO , VISCONTI MARCO , LI BASSI GIUSEPPE
发明人： NORCINI GABRIELE , CASIRAGHI ANGELO , VISCONTI MARCO , LI BASSI GIUSEPPE
IPC分类号： C07D335/12 , C07D333/76 , C07D335/16 , C07D339/08 , G03F7/004 , G03F7/038 , G03F7/031
CPC分类号： C07D339/08 , C07D333/76 , C07D335/16 , G03F7/0045 , G03F7/038
摘要： The present invention relates to sulfonium salts, to methods for their preparation and to radiation curable compositions containing them as photoinitiators.
摘要翻译：本发明涉及锍盐，其制备方法和含有它们作为光引发剂的可辐射固化组合物。

10. 发明申请

WO02085832A3 SOLID MIXTURES OF ALPHA-HYDROXYCARBONYL DERIVATIVES OF ALPHA-METHYLSTYRENE OLIGOMERS AND THEIR USE 审中-公开
标题翻译： α-甲基苯乙烯低聚物的α-羟基羰基衍生物的固体混合物及其使用
公开(公告)号：WO02085832A3
公开(公告)日：2002-12-27
申请号：PCT/EP0203674
申请日：2002-04-03
申请人： LAMBERTI SPA , VISCONTI MARCO , NORCINI GABRIELE , LI BASSI GIUSEPPE
发明人： VISCONTI MARCO , NORCINI GABRIELE , LI BASSI GIUSEPPE
IPC分类号： C07C45/81 , C07C49/83 , C08F2/50 , C08F6/12 , C08F8/48 , G03F7/031
CPC分类号： G03F7/031 , C07C45/81 , C07C49/83 , C08F2/50 , C08F6/12
摘要： The present invention refers to solid mixtures of alpha hydroxycarbonyl derivatives of alpha-methylstyrene oligomers containing at least 90 % of the dimer isomers, the dimer isomer ratio being between 2.5 and 7, to their preparation and to their use as photoinitiators in photopolymerisation.
摘要翻译：本发明涉及α-甲基苯乙烯低聚物的α-羟基羰基衍生物的固体混合物，其含有至少90％的二聚体异构体，二聚体异构体比例为2.5-7，它们的制备及其作为光聚合引发剂的用途。

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