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1. 发明申请

WO2008077399A1 A METHOD OF CONTROLLING A SPRAY DRYER APPARATUS BY REGULATING AN INLET AIR FLOW RATE, AND A SPRAY DRYER APPARATUS 审中-公开
标题翻译：通过调节入口空气流量来控制喷雾干燥器装置的方法和喷雾干燥机装置
公开(公告)号：WO2008077399A1
公开(公告)日：2008-07-03
申请号：PCT/DK2006/050081
申请日：2006-12-22
申请人： NIRO A/S , NIELSEN, Peter Schultz
发明人： NIELSEN, Peter Schultz
IPC分类号： B01D1/16 , F26B21/10 , F26B21/12
CPC分类号： B01D1/16 , F26B3/12
摘要： A method of controlling a spray dryer apparatus having a spray dryer chamber (1), an air inlet (2), an inlet air control system (11) including a fan (13) and an air heater (14), a feed inlet (3), and an exhaust air outlet (4), comprising determining a content (Y) of moisture of inlet air, determining an inlet air temperature set value (T inlet ) in dependence of the inlet air moisture content (Y), determining an inlet air temperature measured value of inlet air between the air heater (14) and the spray dryer chamber (1), and regulating the inlet air temperature in dependence of the inlet air temperature set value and the inlet air temperature measured value, and determining an outlet air temperature of the exhaust air and regulating an inlet air flow rate in dependence of the outlet air temperature.
摘要翻译：一种控制喷雾干燥器设备的方法，该设备具有喷雾干燥器室（1），空气入口（2），包括风扇（13）和空气加热器（14）的入口空气控制系统（11），进料入口 3）和排气出口（4），包括确定入口空气的水分含量（Y），根据入口空气湿度确定入口空气温度设定值（T 入口）含量（Y），确定空气加热器（14）和喷雾干燥器室（1）之间的入口空气的入口空气温度测量值，并根据入口空气温度设定值和入口空气调节入口空气温度温度测量值，以及确定废气的出口空气温度并根据出口空气温度调节入口空气流量。

2. 发明申请

WO2007124745A1 AGGLOMERATION APPARATUS AND METHOD FOR PRODUCING AGGLOMERATED PARTICLES 审中-公开
标题翻译：聚集装置和生产聚集颗粒的方法
公开(公告)号：WO2007124745A1
公开(公告)日：2007-11-08
申请号：PCT/DK2006/000238
申请日：2006-05-02
申请人： NIRO A/S , NIELSEN, Peter Schultz
发明人： NIELSEN, Peter Schultz
IPC分类号： B01J2/16
CPC分类号： B01J2/16 , B29B9/08 , B29L2031/772 , F26B3/08
摘要： The invention relates to an agglomeration apparatus comprising a fluid bed, a source of descending particles, one or more nozzles for atomizing an agglomeration fluid and an outlet for discharging the agglomerated particles. In the fluid bed, the particles are guided towards the outlet and pass an outer and an inner zone. The apparatus provides for the production of an improved agglomerated particulate product with a low content of fine particles.
摘要翻译：本发明涉及包括流化床，下降颗粒源，用于雾化附聚流体的一个或多个喷嘴和用于排出附聚颗粒的出口的附聚装置。在流化床中，颗粒被引导到出口并通过外部和内部区域。该装置提供具有低含量细颗粒的改进的附聚颗粒产物的生产。

3. 发明申请

WO2007071240A1 A PLANT AND A PROCESS FOR PRODUCTION OF TABLETS 审中-公开
标题翻译：一种植物和一种生产片剂的方法
公开(公告)号：WO2007071240A1
公开(公告)日：2007-06-28
申请号：PCT/DK2005/000829
申请日：2005-12-23
申请人： NIRO A/S , MADSEN, Michelle, Milling , SCHWARTZBACK, Henrik
发明人： MADSEN, Michelle, Milling , SCHWARTZBACK, Henrik
IPC分类号： A61J3/10 , A61K9/20
CPC分类号： A61J3/10 , A61K9/2095
摘要： The invention relates to a plant for production of tablets, a process for production of tablets and tablets as such. The plant comprises a mixing device producing a mixed liquid feed of active pharmaceutical ingredient and excipients. A spray dryer atomizes the mixed liquid feed and dried particles with a high flowability are produced. The dried particles are subsequently compressed to tablets in a tablet press. The invention possesses several advantages, including the possibility of using an auto mated rotary tablet press directly, thereby reducing the number of unit operations in the tablet production.
摘要翻译：本发明涉及一种用于生产片剂的植物，片剂和片剂的生产方法。该植物包括产生活性药物成分和赋形剂的混合液体饲料的混合装置。喷雾干燥器使混合液体进料雾化，产生具有高流动性的干燥颗粒。随后将干燥的颗粒在压片机中压制成片剂。本发明具有几个优点，包括直接使用自动旋转式压片机的可能性，从而减少片剂生产中的单元操作的数量。

4. 发明申请

WO2005061089A1 A METHOD AND APPARATUS FOR PRODUCING MICRO PARTICLES 审中-公开
标题翻译：一种生产微粒子的方法和装置
公开(公告)号：WO2005061089A1
公开(公告)日：2005-07-07
申请号：PCT/DK2004/000617
申请日：2004-09-16
申请人： NIRO A/S , HANSEN, Ove, Emil , PAGE, Trevor, Gordon
发明人： HANSEN, Ove, Emil , PAGE, Trevor, Gordon
IPC分类号： B01J2/04
CPC分类号： B01D1/18 , B01J2/04 , B29C43/34 , B29C2043/3494
摘要： The invention relates to a method and apparatus for producing substantially monodisperse micro particles preferably of heat sensible material using a carrier gas and a drying gas. Relatively dense micro particles with diameters in the range 1-120µm with a very narrow span.
摘要翻译：本发明涉及一种用于使用载气和干燥气体来生产基本上单分散微粒子的方法和装置，其优选地是热敏材料。直径在1-120μm范围内的相对密集的微粒具有非常窄的跨度。

5. 发明申请

WO2003086091A1 PROCESS AND PLANT FOR EVAPORATIVE CONCENTRATION AND CRYSTALLIZATION OF A VISCOUS LACTOSE-CONTAINING AQUEOUS LIQUID 审中-公开
标题翻译：含有乳酸的含水乳液的蒸发浓缩和结晶的方法和设备
公开(公告)号：WO2003086091A1
公开(公告)日：2003-10-23
申请号：PCT/DK2003/000193
申请日：2003-03-21
申请人： NIRO A/S , HENNINGFIELD, Thomas, David , DINESEN, Richard, Andrew
发明人： HENNINGFIELD, Thomas, David , DINESEN, Richard, Andrew
IPC分类号： A23C1/12
CPC分类号： C13B30/02 , A23C21/00 , C13K5/00
摘要： Crystalline α-lactose monohydrate is recovered from a viscous lactose-containing aqueous liquid by subjecting said liquid to simultaneous heating, removal of evaporated vapor and mechanical agitation at high shear rate to provide a crystallization promoting decrease of the viscosity of the liquid with crystals formed and suspended therein to progressively concentrate the agitated liquid and simultaneously crystallize lactose therefrom. Subsequent cooling, drying, and disintegration yield particulate α-lactose monohydrate
摘要翻译：通过使所述液体同时加热，除去蒸发的蒸气并在高剪切速率下进行机械搅拌以提供结晶，促进液体形成的粘度降低，形成晶体，从含粘性乳糖的含水液体中回收结晶的α-乳糖一水合物悬浮在其中以逐渐浓缩搅拌的液体并同时从其中结晶乳糖。随后冷却，干燥和分解产生颗粒状α-乳糖一水合物

6. 发明申请

WO1995031276A1 COMPACTING GRANULATOR 审中-公开
标题翻译：压实造粒机
公开(公告)号：WO1995031276A1
公开(公告)日：1995-11-23
申请号：PCT/DK1995000190
申请日：1995-05-15
申请人： NIRO A/S , FUNDER, Christian, Reedtz , HANSEN, Morten, Mohr , HANSEN, Ove, Emil , HEIN, Torben , LARSEN, Tage, Moller , NIELSEN, Elo
发明人： NIRO A/S
IPC分类号： B01J02/12
CPC分类号： B01J2/24 , B01J2/12
摘要： A compacting granulator for continuous, compacting granulation comprises a substantially horizontal rotatable drum, through which an eccentric shaft extends, which carries compacting means which partly transfer substantial amounts of energy to the granulate possible for attainment of a high degree of compacting, partly hurl up the material under treatment, so that the material, while hurled up, is brought in intimate contact with a treatment liquid sprayed through the nozzle. A stationary scraper as well as nozzles with individual feed supply ensure great flexibility and a reliable operation.
摘要翻译：用于连续压实造粒的压实造粒机包括基本上水平的可旋转滚筒，偏心轴穿过该滚筒，其承载压实装置，该压实装置部分地将大量能量部分地转移到颗粒，以实现高度的压实，部分地上升处理过的材料，使得材料在被喷出的同时与通过喷嘴喷射的处理液体紧密接触。固定刮刀以及具有单独进料供应的喷嘴确保了很大的灵活性和可靠的操作。

7. 发明申请

WO2009006891A1 METHOD FOR FREEZE-DRYING A PRODUCT AND FREEZE-DRYING APPARATUS FOR CARRYING OUT THE METHOD 审中-公开
标题翻译：冷冻干燥方法及冷冻干燥装置的实施方法
公开(公告)号：WO2009006891A1
公开(公告)日：2009-01-15
申请号：PCT/DK2007/050089
申请日：2007-07-10
申请人： NIRO A/S , LASSEN, Steen , PEDERSEN, Morten Woldsted
发明人： LASSEN, Steen , PEDERSEN, Morten Woldsted
IPC分类号： F26B5/06
CPC分类号： F26B5/06
摘要： A method for freeze-drying a product using a freeze-drying apparatus, said method comprising the steps of providing a freeze-drying apparatus 5 (1), providing said freeze-drying apparatus with a plurality of product receptacles (11) comprising a solid bottom (14) and an open top (13), and with a plurality of heating elements (10) comprising a bottom surface (16) and a top surface (15), providing a product to be freeze- dried in each of said product receptacles (11), placing said product 10 receptacles (11) and said heating elements (10) above one another such that at least one heating element (10) is placed between each two product receptacles (11), and providing heat radiation from said heating element (10) to said product, wherein the energy of said heat radiation is dependent on whether the heat is transferred directly to said product 15 or through the bottom (14) of said product receptacle (11) to said product.
摘要翻译：一种使用冷冻干燥装置对产品进行冷冻干燥的方法，所述方法包括以下步骤：提供冷冻干燥装置5（1），为冷冻干燥装置提供多个产品容器（11），其包括固体底部（14）和开口顶部（13），以及包括底部表面（16）和顶部表面（15）的多个加热元件（10），提供在每个所述产品中被冷冻干燥的产品容器（11），将所述产品10容器（11）和所述加热元件（10）放置在彼此之上，使得至少一个加热元件（10）被放置在每个两个产品容器（11）之间，并且提供来自所述加热元件（10）到所述产品，其中所述热辐射的能量取决于热量是直接传递到所述产品15还是通过所述产品容器（11）的底部（14）转移到所述产品。

8. 发明申请

WO2007071235A1 A NOZZLE ARRANGEMENT AND A METHOD OF MOUNTING THE NOZZLE ARRANGEMENT IN A WALL OF A SPRAY DRYING APPARATUS 审中-公开
标题翻译：喷嘴布置方法和安装喷雾干燥装置的喷嘴布置方法
公开(公告)号：WO2007071235A1
公开(公告)日：2007-06-28
申请号：PCT/DK2005/000808
申请日：2005-12-20
申请人： NIRO A/S , NOWAK, Martin
发明人： NOWAK, Martin
IPC分类号： F26B3/12 , B01D1/20 , B05B15/06
CPC分类号： B01D1/20 , F26B3/12
摘要： The nozzle arrangement (10) has a nozzle lance (11) and a nozzle having a longitudinal axis. A securing device (20) is adapted to secure the nozzle lance to a ceiling or wall of a drying chamber of the spray drying apparatus. The securing device comprises adjustment means including at least a first and a second adjustment disk (21, 22) releasably connected with each other, by which it is possible to shift the longitudinal axis of the nozzle.
摘要翻译：喷嘴装置（10）具有喷嘴喷枪（11）和具有纵向轴线的喷嘴。固定装置（20）适于将喷嘴喷枪固定到喷雾干燥装置的干燥室的天花板或墙壁上。固定装置包括调节装置，该调节装置至少包括彼此可释放地连接的第一和第二调节盘（21,22），借此可以使喷嘴的纵向轴线移动。

9. 发明申请

WO2007036227A1 AN APPARATUS AND A PROCESS FOR DRYING HIGH CARBOHYDRATE CONTENT LIQUIDS 审中-公开
标题翻译：一种用于干燥高碳水化合物液体的装置和方法
公开(公告)号：WO2007036227A1
公开(公告)日：2007-04-05
申请号：PCT/DK2005/000624
申请日：2005-09-30
申请人： NIRO A/S , BONKE, Johnny
发明人： BONKE, Johnny
IPC分类号： A23C1/04 , A23C21/00
CPC分类号： F26B3/12 , A23C1/04 , A23C21/00 , F26B3/08
摘要： The invention relates to an apparatus for drying a liquid predominately containing solid matter of carbohydrates to a non-sticky powder. The apparatus comprises a spray drying chamber (5) in the upper part of which a spraying element (4) capable of atomizing liquid predominately containing solid matter of carbohydrates to droplets is positioned, means (6) for supplying a drying gas to the atomized droplets for partially drying thereof to moist particles, and a residence device (9) for post-crystallisation of the moist particles received from the drying chamber to a non-sticky powder. The apparatus further comprises a filter element (7) arranged internally in the spraying chamber, and means (16) for withdrawing the spent drying gas through the filter element. The apparatus is suitable for treating liquids with a high content of carbohydrates such as whey and whey permeate. Also disclosed is a process for producing non-sticky powders.
摘要翻译：本发明涉及一种用于将主要含有碳水化合物固体物质的液体干燥成非粘性粉末的装置。该装置包括一个喷雾干燥室（5），其上部设有能够将主要含有碳水化合物固体物质的液体雾化至液滴的喷射元件（4），用于将干燥气体供应至雾化液滴的装置（6）用于将其部分干燥成湿颗粒;以及用于将从干燥室接收的湿颗粒后结晶至非粘性粉末的停留装置（9）。该装置还包括布置在喷雾室内部的过滤元件（7），以及用于通过过滤器元件抽出废的干燥气体的装置（16）。该设备适用于处理高含量碳水化合物如乳清和乳清渗透物的液体。还公开了生产非粘性粉末的方法。

10. 发明申请

WO1998000001A2 A METHOD OF CLEANING A FILTER UNIT, AND A FILTER UNIT FOR FILTERING GAS 审中-公开
标题翻译：清洗过滤器的方法和用于过滤气体的过滤器单元
公开(公告)号：WO1998000001A2
公开(公告)日：1998-01-08
申请号：PCT/DK1997000495
申请日：1997-10-31
申请人： NIRO A/S , BACH, Poul , MOLLER, Henning, Birger , PIPPER, Nicolai
发明人： NIRO A/S
IPC分类号： B01D46/04
CPC分类号： B01D46/0068 , B01D46/0082 , B01D46/04 , B01D46/4281
摘要： A filter unit (1) has a plurality of filter elements (7) extending from a plate (6, 32) which divides the unit into a lower inlet side (9) for gas carrying product and an upper outlet side (8) for filtered clean gas. A cleaning-in-place of the filter elements is performed by supplying cleaning liquid in a sequence of several separate liquid pulses which are mixed with the pressurized gas pulses. The ejection of the individual pulse of pressurized gas is initiated at the earliest simultaneously with or after initiation of ejection of the corresponding pulse of cleaning liquid.
摘要翻译：过滤器单元（1）具有从板（6,32）延伸的多个过滤器元件（7），所述板将所述单元分成用于气体输送产品的下入口侧（9）和用于过滤的上出口侧（8）清洁气体。通过以与加压气体脉冲混合的几个分开的液体脉冲的顺序供应清洁液体来进行过滤元件的清洗。加压气体的单个脉冲的喷射在最初同时或者在相应的清洗液脉冲的喷射开始之后开始。

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