专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2013022982A3 PEGYLATED TYROSYL-TRNA SYNTHETASE POLYPEPTIDES 审中-公开
标题翻译：聚对苯二甲酸二异氰酸酯合成酶多糖
公开(公告)号：WO2013022982A3
公开(公告)日：2013-04-25
申请号：PCT/US2012050012
申请日：2012-08-08
申请人： ATYR PHARMA INC , WATKINS JEFFRY D , BUECHLER YING JI , WU CHI-FANG , DO MINH-HA , VASSEROT ALAIN P , MENDLEIN JOHN D
发明人： WATKINS JEFFRY D , BUECHLER YING JI , WU CHI-FANG , DO MINH-HA , VASSEROT ALAIN P , MENDLEIN JOHN D
IPC分类号： C12N9/00 , A61K38/43 , A61P7/00 , C12N11/10
CPC分类号： C12N9/93 , A61K38/00 , A61K47/60 , C12Y601/01001
摘要： The present invention provides PEGylated tyrosyl-tRNA synthetase (YRS) polypeptides, compositions comprising the same, and methods of using such polypeptides and compositions for treating or diagnosing a variety of conditions. The PEGylated YRS polypeptides of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic properties compared to non-PEGylated YRS polypeptides.
摘要翻译：本发明提供聚乙二醇化酪氨酰-tRNA合成酶（YRS）多肽，包含其的组合物，以及使用这些多肽和组合物治疗或诊断各种病症的方法。本发明的聚乙二醇化YRS多肽与非聚乙二醇化的YRS多肽相比具有改善的控制释放性质，稳定性，半衰期和其他药代动力学性质。

2. 发明申请

WO2011139853A3 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF ALANYL TRNA SYNTHETASES 审中-公开
标题翻译：与ALANYL TRNA合成蛋白质蛋白相关的治疗，诊断和抗体组合物的创新发现
公开(公告)号：WO2011139853A3
公开(公告)日：2012-05-10
申请号：PCT/US2011034387
申请日：2011-04-28
申请人： ATYR PHARMA INC , PANGU BIOPHARMA LTD , GREENE LESLIE ANN , CHIANG KYLE P , HONG FEI , VASSEROT ALAIN P , LO WING-SZE , WATKINS JEFFRY D , MENDLEIN JOHN D , QUINN CHERYL L
发明人： GREENE LESLIE ANN , CHIANG KYLE P , HONG FEI , VASSEROT ALAIN P , LO WING-SZE , WATKINS JEFFRY D , MENDLEIN JOHN D , QUINN CHERYL L
IPC分类号： C12N9/00 , A61K38/43 , C07K16/40 , C07K19/00 , C12N15/113 , C12N15/52 , G01N33/68
CPC分类号： C07K16/40 , A61K35/12 , A61K38/00 , A61K38/53 , C07K14/00 , C07K2317/24 , C07K2317/622 , C07K2319/33 , C12N5/0602 , C12N9/18 , C12N9/93 , C12N9/96 , C12Y601/01 , C12Y601/01007 , G01N33/5008 , G01N33/573 , G01N33/68 , G01N2333/9015 , G01N2500/00
摘要： Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
摘要翻译：提供了包含新确定的氨酰-tRNA合成酶的蛋白质片段的组合物，其编码它们的多核苷酸及其互补物，相关试剂及其在诊断，药物发现，研究和治疗应用中的使用方法。

3. 发明申请

WO2012048125A3 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED PROTEIN FRAGMENTS OF TRYPTOPHANYL TRNA SYNTHETASES 审中-公开
公开(公告)号：WO2012048125A3
公开(公告)日：2012-04-12
申请号：PCT/US2011/055130
申请日：2011-10-06
申请人： ATYR PHARMA, INC. , PANGU BIOPHARMA LIMITED , GREENE, Leslie Ann , CHIANG, Kyle P. , HONG, Fei , VASSEROT, Alain P. , LO, Wing-Sze , WATKINS, Jeffry D. , QUINN, Cheryl L. , MENDLEIN, John D.
发明人： GREENE, Leslie Ann , CHIANG, Kyle P. , HONG, Fei , VASSEROT, Alain P. , LO, Wing-Sze , WATKINS, Jeffry D. , QUINN, Cheryl L. , MENDLEIN, John D.
IPC分类号： A61K38/16 , A61K38/10 , A61K38/08 , A61K39/395 , A61P3/00 , A61P9/00 , A61P29/00
摘要： Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.

4. 发明申请

WO2011140135A3 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF METHIONYL-TRNA SYNTHETASES 审中-公开
标题翻译：创新发现与甲基丙METH氨酰合成酶蛋白片段有关的治疗，诊断和抗体组合物
公开(公告)号：WO2011140135A3
公开(公告)日：2012-04-05
申请号：PCT/US2011035056
申请日：2011-05-03
申请人： ATYR PHARMA INC , PANGU BIOPHARMA LTD , GREENE LESLIE ANN , CHIANG KYLE P , HONG FEI , VASSEROT ALAIN P , LO WING-SZE , WATKINS JEFFRY D , MENDLEIN JOHN D , QUINN CHERYL L
发明人： GREENE LESLIE ANN , CHIANG KYLE P , HONG FEI , VASSEROT ALAIN P , LO WING-SZE , WATKINS JEFFRY D , MENDLEIN JOHN D , QUINN CHERYL L
IPC分类号： A61K38/16 , A61K39/395 , A61P3/10 , A61P29/00 , A61P35/00 , C07K14/525
CPC分类号： C07K16/40 , A61K38/53 , C07K2317/24 , C07K2317/622 , C07K2317/76 , C07K2317/92 , C12N5/0602 , C12N9/93 , C12N9/96 , C12Y601/01 , C12Y601/0101 , G01N33/573 , G01N33/68 , G01N2333/9015
摘要： Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
摘要翻译：提供了包含氨基酰基-tRNA合成酶的新鉴定的蛋白片段，编码它们的多核苷酸及其互补物，相关试剂及其在诊断，药物开发，研究和治疗应用中的使用方法。

5. 发明申请

WO2011150279A2 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF GLUTAMINYL-TRNA SYNTHETASES 审中-公开
标题翻译：与谷氨酰胺-TRNA合成蛋白片段相关的治疗，诊断和抗体组合物的创新发现
公开(公告)号：WO2011150279A2
公开(公告)日：2011-12-01
申请号：PCT/US2011/038240
申请日：2011-05-26
申请人： ATYR PHARMA, INC. , PANGU BIOPHARMA LIMITED , GREENE, Leslie, Ann , CHIANG, Kyle, P. , HONG, Fei , VASSEROT, Alain, P. , LO, Wing-Sze , WATKINS, Jeffry, D. , QUINN, Cheryl, L. , MENDLEIN, John, D.
发明人： GREENE, Leslie, Ann , CHIANG, Kyle, P. , HONG, Fei , VASSEROT, Alain, P. , LO, Wing-Sze , WATKINS, Jeffry, D. , QUINN, Cheryl, L. , MENDLEIN, John, D.
IPC分类号： A61K38/16 , A61K38/08 , A61K38/10 , A61K39/395 , A61P35/00 , A61P3/10 , A61P29/00
CPC分类号： C07K16/40 , A61K9/0019 , A61K38/00 , C07K2317/24 , C07K2317/34 , C07K2317/92 , C12N9/93 , C12Y601/01 , G01N33/573 , G01N2333/9015
摘要： Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
摘要翻译：提供了包含新确定的氨酰-tRNA合成酶的蛋白质片段的组合物，其编码它们的多核苷酸及其互补物，相关试剂及其在诊断，药物发现，研究和治疗应用中的使用方法。

6. 发明申请

WO2011146410A2 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF LEUCYL-TRNA SYNTHETASES 审中-公开
标题翻译：与LEUCYL-TRNA合成蛋白质蛋白相关的治疗，诊断和抗体组合物的创新发现
公开(公告)号：WO2011146410A2
公开(公告)日：2011-11-24
申请号：PCT/US2011/036684
申请日：2011-05-16
申请人： ATYR PHARMA, INC. , PANGU BIOPHARMA LIMITED , GREENE, Leslie, Ann , CHIANG, Kyle, P. , HONG, Fei , VASSEROT, Alain, P. , LO, Wing-Sze , WATKINS, Jeffry, D. , QUINN, Cheryl, L. , MENDLEIN, John, D.
发明人： GREENE, Leslie, Ann , CHIANG, Kyle, P. , HONG, Fei , VASSEROT, Alain, P. , LO, Wing-Sze , WATKINS, Jeffry, D. , QUINN, Cheryl, L. , MENDLEIN, John, D.
CPC分类号： C12N9/93 , A61K38/00 , A61K38/53 , A61K2039/505 , C07K16/40 , C12Q1/527 , C12Y601/01 , G01N33/573
摘要： Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
摘要翻译：提供了包含新确定的氨酰-tRNA合成酶的蛋白质片段的组合物，其编码它们的多核苷酸及其互补物，相关试剂及其在诊断，药物发现，研究和治疗应用中的使用方法。

7. 发明申请

WO2011139907A2 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF VALYL TRNA SYNTHETASES 审中-公开
标题翻译：与VALYL TRNA合成蛋白片段相关的治疗，诊断和抗体组合物的创新发现
公开(公告)号：WO2011139907A2
公开(公告)日：2011-11-10
申请号：PCT/US2011/034626
申请日：2011-04-29
申请人： ATYR PHARMA, INC. , PANGU BIOPHARMA LIMITED , GREENE, Leslie, Ann , CHIANG, Kyle, P. , HONG, Fei , VASSEROT, Alain, P. , LO, Wing-Sze , WATKINS, Jeffry, D. , MENDLEIN, John, D. , QUINN, Cheryl, L.
发明人： GREENE, Leslie, Ann , CHIANG, Kyle, P. , HONG, Fei , VASSEROT, Alain, P. , LO, Wing-Sze , WATKINS, Jeffry, D. , MENDLEIN, John, D. , QUINN, Cheryl, L.
IPC分类号： A61K38/16 , A61K38/17 , A61K39/395 , A61K48/00 , A61P35/00 , A61P3/10 , A61P29/00
CPC分类号： C07K16/40 , A61K9/0019 , A61K9/19 , A61K38/53 , C07K2317/24 , C07K2317/34 , C07K2317/92 , C12N5/0602 , C12N9/93 , C12N9/96 , C12Y601/01 , C12Y601/01009 , G01N33/5011 , G01N33/573 , G01N33/68 , G01N2333/9015 , G01N2500/10
摘要： Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
摘要翻译：提供了包含新确定的氨酰-tRNA合成酶的蛋白质片段的组合物，其编码它们的多核苷酸及其互补物，相关试剂及其在诊断，药物发现，研究和治疗应用中的使用方法。

8. 发明申请

WO2011139714A2 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF CYSTEINYL-TRNA SYNTHETASE 审中-公开
标题翻译：与CYSTEINYL-TRNA SYNTHETASE蛋白质片段相关的治疗，诊断和抗体组合物的创新发现
公开(公告)号：WO2011139714A2
公开(公告)日：2011-11-10
申请号：PCT/US2011/033988
申请日：2011-04-26
申请人： ATYR PHARMA, INC. , PANGU BIOPHARMA LIMITED , GREENE, Leslie Ann , CHIANG, Kyle, P. , HONG, Fei , VASSEROT, Alain, P. , LO, Wing-Sze , WATKINS, Jeffry, D. , MENDLEIN, John, D. , QUINN, Cheryl, L.
发明人： GREENE, Leslie Ann , CHIANG, Kyle, P. , HONG, Fei , VASSEROT, Alain, P. , LO, Wing-Sze , WATKINS, Jeffry, D. , MENDLEIN, John, D. , QUINN, Cheryl, L.
IPC分类号： A61K38/16 , A61K38/17 , A61K39/395 , A61P35/00 , A61P29/00 , A61P3/00
CPC分类号： C07K16/40 , A61K38/00 , A61K39/39591 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/76 , C12N9/93 , C12Y601/01016 , G01N33/573 , G01N2333/9015
摘要： Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
摘要翻译：提供了包含新确定的氨酰-tRNA合成酶的蛋白质片段的组合物，其编码它们的多核苷酸及其互补物，相关试剂及其在诊断，药物发现，研究和治疗应用中的使用方法。

9. 发明申请

WO1998017178A1 MEASUREMENT OF OBJECT LAYER THICKNESS USING ULTRA-SONIC METHODS AND DEVICES 审中-公开
标题翻译：使用超声波方法和器件测量物体层厚度
公开(公告)号：WO1998017178A1
公开(公告)日：1998-04-30
申请号：PCT/US1997018993
申请日：1997-10-21
申请人： LANG, Philipp , GRAMPP, Stephan , MENDLEIN, John, D.
IPC分类号： A61B08/00
CPC分类号： A61B5/4872 , A61B5/6843 , A61B8/0858 , A61B8/4272
摘要： The present invention provides for a method of measuring layer thickness in an object comprising transmitting at least a first and a second ultra-sonic pulse from at least a first and second position; measuring at least one reflective distance from the first pulse and at least one reflective distance from the second pulse, wherein the reflective distance is from the object's external surface (or probe) to a reflective interface (5) of at least one layer; selecting the reflective distance having the shortest reflective distance to indicate the distance between the external surface (or probe surface) and the reflective interface (5) of at least one layer, wherein the selecting of the shortest reflective distance reduces ultra-sonic transmission parallax of the first and second pulses relative to a plane (4) in the object.
摘要翻译：本发明提供一种测量物体中的层厚度的方法，包括从至少第一和第二位置至少传输第一和第二超声波脉冲; 测量与第一脉冲的至少一个反射距离和距离第二脉冲的至少一个反射距离，其中反射距离是从物体的外表面（或探针）到至少一层的反射界面（5）; 选择具有最短反射距离的反射距离以指示至少一层的外表面（或探针表面）和反射界面（5）之间的距离，其中选择最短反射距离减小超声波透射视差相对于物体中的平面（4）的第一和第二脉冲。

10. 发明申请

WO2012021249A2 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF HISTIDYL-TRNA SYNTHETASES 审中-公开
标题翻译：创新发现与HISTIDYL-TRNA合成酶蛋白片段有关的治疗，诊断和抗体组合物
公开(公告)号：WO2012021249A2
公开(公告)日：2012-02-16
申请号：PCT/US2011/043758
申请日：2011-07-12
申请人： ATYR PHARMA, INC. , PANGU BIOPHARMA LIMITED , GREENE, Leslie, Ann , CHIANG, Kyle, P. , HONG, Fei , VASSEROT, Alain, P. , LO, Wing-Sze , WATKINS, Jeffry, D. , QUINN, Cheryl, L. , MENDLEIN, John, D.
发明人： GREENE, Leslie, Ann , CHIANG, Kyle, P. , HONG, Fei , VASSEROT, Alain, P. , LO, Wing-Sze , WATKINS, Jeffry, D. , QUINN, Cheryl, L. , MENDLEIN, John, D.
IPC分类号： A61K38/16 , A61K38/10 , A61K38/08 , A61K39/395 , A61P35/00 , A61P3/10 , A61P3/00
CPC分类号： C12N9/93 , A61K38/00 , A61K38/53 , C07K16/40 , C12N5/0602 , C12N9/96 , C12Y601/01 , C12Y601/01021 , G01N33/68
摘要： Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
摘要翻译：提供了包含氨酰基-tRNA合成酶的新鉴定的蛋白片段，编码它们的多核苷酸及其互补物的组合物，相关试剂及其在诊断，药物开发，研究和治疗应用中的使用方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式