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1. 发明申请

WO2007106344A2 OPTICAL ASSAY APPARATUS AND METHODS 审中-公开
标题翻译：光学测试装置和方法
公开(公告)号：WO2007106344A2
公开(公告)日：2007-09-20
申请号：PCT/US2007/005691
申请日：2007-03-07
申请人： RESEARCH INTERNATIONAL, INC. , SAASKI, Elric, W. , MCCRAE, David, A.
发明人： SAASKI, Elric, W. , MCCRAE, David, A.
IPC分类号： G01J3/02
CPC分类号： G01N21/552 , G01N21/0303 , G01N21/07 , G01N21/6428 , G01N21/645 , G01N21/648 , G01N21/7703 , G01N2021/6482 , G01N2021/7786 , G01N2021/7796 , Y10S435/808 , Y10S436/805
摘要： Optical assay apparatus (11) and methods having an optical assay cup (10) for detecting analytes (52) in a sample fluid. The cup's sidewall (14) may include an optical waveguide (28) having a detection coating (50) on its inner surface (32). During use, the waveguide (28) receives evanescent or darkfield interrogation light (24a, 24b), interrogates the cup's interior volume (68) with it, and emits signal light (58) as a function of the analytes. The detection coating may have fluid or non-fluid detection layers (51a-c), at least part of which may form at least part of a waveguide (29) for the interrogation light. The cup may be spun during use, such as to centrifugal ly-concentrate any high-density analytes towards cup's sidewall. The assay apparatus may further include an interrogation light source (26), a cover (16) or spinning apparatus (25) for the cup, and an optical detector (60) for the signal light.
摘要翻译：光学测定装置（11）和具有用于检测样品流体中的分析物（52）的光学测定杯（10）的方法。杯的侧壁（14）可以包括在其内表面（32）上具有检测涂层（50）的光波导（28）。在使用期间，波导（28）接收消逝或暗场询问光（24a，24b），用它询问杯子的内部容积（68），并发射作为分析物的函数的信号光（58）。检测涂层可以具有流体或非流体检测层（51a-c），其至少部分可以形成用于询问光的波导（29）的至少一部分。杯子可以在使用过程中旋转，例如将任何高密度分析物离心浓缩到杯子的侧壁。测定装置还可以包括用于杯子的询问光源（26），盖（16）或旋转设备（25）和用于信号光的光学检测器（60）。

2. 发明申请

WO2007106344A3 OPTICAL ASSAY APPARATUS AND METHODS 审中-公开
标题翻译：光学测试装置和方法
公开(公告)号：WO2007106344A3
公开(公告)日：2008-10-30
申请号：PCT/US2007005691
申请日：2007-03-07
申请人： RES INT INC , SAASKI ELRIC W , MCCRAE DAVID A
发明人： SAASKI ELRIC W , MCCRAE DAVID A
IPC分类号： C12M1/34
CPC分类号： G01N21/552 , G01N21/0303 , G01N21/07 , G01N21/6428 , G01N21/645 , G01N21/648 , G01N21/7703 , G01N2021/6482 , G01N2021/7786 , G01N2021/7796 , Y10S435/808 , Y10S436/805
摘要： Optical assay apparatus (11) and methods having an optical assay cup (10) for detecting analytes (52) in a sample fluid. The cup's sidewall (14) may include an optical waveguide (28) having a detection coating (50) on its inner surface (32). During use, the waveguide (28) receives evanescent or darkfield interrogation light (24a, 24b), interrogates the cup's interior volume (68) with it, and emits signal light (58) as a function of the analytes. The detection coating may have fluid or non-fluid detection layers (51a-c), at least part of which may form at least part of a waveguide (29) for the interrogation light. The cup may be spun during use, such as to centrifugal ly-concentrate any high-density analytes towards cup's sidewall. The assay apparatus may further include an interrogation light source (26), a cover (16) or spinning apparatus (25) for the cup, and an optical detector (60) for the signal light.
摘要翻译：光学测定装置（11）和具有用于检测样品流体中的分析物（52）的光学测定杯（10）的方法。杯的侧壁（14）可以包括在其内表面（32）上具有检测涂层（50）的光波导（28）。在使用期间，波导（28）接收消逝或暗场询问光（24a，24b），用它询问杯子的内部容积（68），并发射作为分析物的函数的信号光（58）。检测涂层可以具有流体或非流体检测层（51a-c），其至少部分可以形成用于询问光的波导（29）的至少一部分。杯子可以在使用过程中旋转，例如将任何高密度分析物离心浓缩到杯子的侧壁。测定装置还可以包括用于杯子的询问光源（26），盖（16）或旋转设备（25）和用于信号光的光学检测器（60）。

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