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1. 发明申请

WO2009146216A2 ANTIOXIDANT INFLAMMATION MODULATORS: NOVEL DERIVATIVES OF OLEANOLIC ACID 审中-公开
标题翻译：抗氧化剂溶解调节剂：油酸的新型衍生物
公开(公告)号：WO2009146216A2
公开(公告)日：2009-12-03
申请号：PCT/US2009041173
申请日：2009-04-20
申请人： REATA PHARMACEUTICALS INC , JIANG XIN , GREINER JACK , MARAVETZ LESTER L , SZUCS STEPHEN S , VISNICK MELEAN
发明人： JIANG XIN , GREINER JACK , MARAVETZ LESTER L , SZUCS STEPHEN S , VISNICK MELEAN
IPC分类号： C07J63/00 , A61K31/56 , A61P25/28 , A61P35/00
CPC分类号： C07J63/008
摘要： Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
摘要翻译：本文公开了新的齐墩果酸衍生物。还公开了制备这些化合物的方法。本发明的齐墩果酸衍生物可用于治疗和预防许多疾病，包括癌症，神经障碍，炎症和涉及氧化应激的病态。

2. 发明申请

WO1997012886A1 HERBICIDAL HETEROCYCLIC BENZISOXAZOLES AND BENZISOXAZOLIDINONES 审中-公开
标题翻译：除草剂杂环烷基苯并咪唑并苯并咪唑啉酮
公开(公告)号：WO1997012886A1
公开(公告)日：1997-04-10
申请号：PCT/US1996015826
申请日：1996-10-02
申请人： FMC CORPORATION , THEODORIDIS, George , MARAVETZ, Lester, L. , CRAWFORD, Scott, D.
发明人： FMC CORPORATION
IPC分类号： C07D413/10
CPC分类号： C07D413/04 , A01N43/80
摘要： Disclosed are novel herbicidal heterocyclic benzisoxazoles and benzisoxazolidinones of formula (I), wherein A is (a), (b), (c); U=N or NR; R=H, alkyl, alkenyl, alkoxycarbonylalkyl, alkoxycarbonylhaloalkyl, benzyl, phenyl, or cyanoalkyl; X=CO or CR ; R =H, CH2CN, CH2OCH3, alkyl, alkenyl, alkynyl, haloalkyl, or amino; R =halogen, alkyl, aryl, haloalkyl, alkoxycarbonyl, arylalkyl, or substituted haloalkyl; R =haloalkyl or alkyl; Y=H, halogen, cyano, or haloalkyl; Z=H or halogen.
摘要翻译：公开了式（I）的新型除草杂环苯并异恶唑和苯并异恶唑烷酮，其中A是（a），（b），（c）; U = N或NR; R = H，烷基，烯基，烷氧基羰基烷基，烷氧基羰基卤代烷基，苄基，苯基或氰基烷基; X = CO或CR <2>; R 1 = H，CH 2 CN，CH 2 OCH 3，烷基，烯基，炔基，卤代烷基或氨基; R 2 =卤素，烷基，芳基，卤代烷基，烷氧基羰基，芳烷基或取代的卤代烷基; R 3 =卤代烷基或烷基; Y = H，卤素，氰基或卤代烷基; Z = H或卤素。

3. 发明申请

WO2009146216A3 ANTIOXIDANT INFLAMMATION MODULATORS: NOVEL DERIVATIVES OF OLEANOLIC ACID 审中-公开
公开(公告)号：WO2009146216A3
公开(公告)日：2009-12-03
申请号：PCT/US2009/041173
申请日：2009-04-20
申请人： REATA PHARMACEUTICALS. INC. , JIANG, Xin , GREINER, Jack , MARAVETZ, Lester, L. , SZUCS, Stephen, S. , VISNICK, Melean
发明人： JIANG, Xin , GREINER, Jack , MARAVETZ, Lester, L. , SZUCS, Stephen, S. , VISNICK, Melean
IPC分类号： C07J63/00 , A61K31/56 , A61P25/28 , A61P35/00
摘要： Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.

4. 发明申请

WO2004105488A1 HYDRAZONE DERIVATIVES FOR COMBATTING HARMFUL INSECTS AND ARACHNIDS 审中-公开
标题翻译：用于混合有害物质和毒素的氢氯吡啶衍生物
公开(公告)号：WO2004105488A1
公开(公告)日：2004-12-09
申请号：PCT/EP2004/005681
申请日：2004-05-26
申请人： BASF AKTIENGESELLSCHAFT , HOFMANN, Michael , KORDES, Markus , LANG, Udo , BAUMANN, Ernst , VON DEYN, Wolfgang , PUHL, Michael , SCHMIDT, Thomas , STEINER, Gerd , TREACY, Michael, F. , CULBERTSON, Deborah, L. , BUCCI, Toni , HONG-MING, Shieh , MARAVETZ, Lester, L.
发明人： HOFMANN, Michael , KORDES, Markus , LANG, Udo , BAUMANN, Ernst , VON DEYN, Wolfgang , PUHL, Michael , SCHMIDT, Thomas , STEINER, Gerd , TREACY, Michael, F. , CULBERTSON, Deborah, L. , BUCCI, Toni , HONG-MING, Shieh , MARAVETZ, Lester, L.
IPC分类号： A01N37/28
CPC分类号： C07D213/86 , A01N37/28 , A01N43/08 , A01N43/10 , A01N43/12 , A01N43/38 , A01N43/40 , A01N43/50 , A01N43/54 , A01N43/56 , A01N43/60 , A01N43/90 , A01N51/00 , C07D231/14 , C07D261/18 , C07D405/12 , C07D409/12 , C07D413/12
摘要： The present invention relates to a method for combatting insects or arachnids which comprises contacting the insects or the arachnids, their habitat, breeding ground, food supply, plant, seed, soil, area, material or environment in which the insects or the arachnids are growing or may grow, or the materials, plants, seeds, soils, surfaces or spaces to be protected from insect or arachnid attack or infestation with a pesticidally effective amount of a compound of the general formula (I) or a salt thereof wherein: Ar is a cyclic radical, n is 0 or 1, X is CO or SO 2 and R 1 to R 4 are as defined in claim 1.
摘要翻译：本发明涉及一种防治昆虫或蜘蛛的方法，包括使昆虫或蜘蛛，其栖息地，繁殖地，食物供应，植物，种子，土壤，昆虫或蜘蛛生长的土壤，区域，物质或环境接触或可能生长的材料，植物，种子，土壤，表面或空间，以防止昆虫或蛛形纲虫攻击或侵染与杀虫有效量的通式（I）化合物或其盐，其中：Ar是环状基团，n为0或1，X为CO或SO 2，R 1至R 4如权利要求1所定义。

5. 发明申请

WO2003051823A1 BETA-AMINO-ALPHA-CYANOACRYLATES AND THEIR USE AS HERBICIDES 审中-公开
标题翻译： β-氨基-AlPHA-氰基丙烯酸酯及其作为除草剂的用途
公开(公告)号：WO2003051823A1
公开(公告)日：2003-06-26
申请号：PCT/EP2002/014355
申请日：2002-12-17
申请人： BASF AKTIENGESELLSCHAFT , EVERSON, Albert, C. , COUGHLIN, Daniel, J. , GUACIARO, Michael, A. , FLEMING, Linda, B. , MARAVETZ, Lester, L. , HUPPATZ, John, L.
发明人： EVERSON, Albert, C. , COUGHLIN, Daniel, J. , GUACIARO, Michael, A. , FLEMING, Linda, B. , MARAVETZ, Lester, L. , HUPPATZ, John, L.
IPC分类号： C07C255/23
CPC分类号： C07C255/23 , A01N37/42 , A01N37/44 , A01N43/08 , A01N43/16 , A01N43/18 , C07C255/30 , C07C255/31 , C07C323/60 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07D307/14 , C07D307/16 , C07D309/04 , C07D309/06
摘要： β-Amino-α-Cyanoacrylates of formula I where the variables have the following meanings: R 1 is n-alkyl, n-alkenyl or alkoxyalkyl; R 2 ,R 3 are alkyl, which may be partially or fully halogenated and/or may carry a substituent from the group consisting of cyano, alkoxy, haloalkoxy, alkylthio, haloalkylthio, C 1 -C 6 -alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl and haloalkylsulfonyl, are alkenyl or alkynyl; or R 2 and R 3 together with the carbon atom to which they are attached form a cycloalkyl ring in which one or two nonadjacent CH 2 groups may be replaced by oxygen or sulfur, and where the cycloalkyl ring may be substituted by halogen or alkyl; R 4 is hydrogen, halogen, cyano or alkyl, where the substituents R 2 , R 3 and R 4 or two of the radicals R 2 , R 3 and R 4 are not simultaneously methyl, and their agriculturally useful salts, processes and intermediates for their preparation; and the use of these compounds or of compositions comprising these compounds for controlling undesirable plants are described.
摘要翻译：其中变量具有以下含义：R 1是正烷基，正 - 链烯基或烷氧基烷基; - 芳基 - R 2是烷基，其可以是部分或完全卤化的和/或可以携带从氰基，烷氧基，卤代烷氧基，烷硫基，卤代烷硫基中的取代基 C 1 -C 6烷基亚磺酰基，卤代烷基亚磺酰基，烷基磺酰基和卤代烷基磺酰基是烯基或炔基; 或R 2和R 3与它们所连接的碳原子一起形成环烷基环，其中一个或两个不相邻的CH 2基团可以被氧或硫取代，并且其中环烷基环可被卤素或烷基取代; R 4是氢，卤素，氰基或烷基，其中取代基R 2，R 3，R 4和/ 或两个基团R 2，R 3，R 3和R 4不同时为甲基，并且它们的农业用途的盐，方法和中间体用于它们制备; 并且描述了这些化合物或包含这些化合物的组合物用于防治不期望的植物的用途。

6. 发明申请

WO1997012884A1 HERBICIDAL 6-HETEROCYCLIC INDAZOLE DERIVATIVES 审中-公开
标题翻译：除草剂6-杂环吲哚衍生物
公开(公告)号：WO1997012884A1
公开(公告)日：1997-04-10
申请号：PCT/US1996015963
申请日：1996-10-03
申请人： FMC CORPORATION , MARAVETZ, Lester, L. , THEODORIDIS, George
发明人： FMC CORPORATION
IPC分类号： C07D403/04
CPC分类号： C07D231/56 , A01N43/56 , A01N43/80 , A01N47/38 , C07D403/04 , C07D403/14 , C07D405/14 , C07D413/14
摘要： Novel herbicidal compounds, compositions containing them, and methods for their preparation and use in controlling weeds are disclosed. The novel herbicidal compounds are indazoles having general formulae (1), wherein Q is (2) or (3); T is H, alkyl, cycloalkyl, alkoxyalkyl, cyanoalkyl, phenylalkyl, alkenyl, haloalkyl, alkenyloxycarbonyl, alkoxycarbonylakenyl, haloalkenyl, alkadienyl, alkynyl, alkylcarbonyl, (dialkylamino)thiocarbonyl, dialkylaminocarbonyl, haloalkylcarbonyl, alkylsulfonyl, haloalkylsulfonyl, alkylaminosulfonyl, cyanothioalkylcarbonyl, dialkylaminosulfonyl, phenylalkylsulfonyl, oxacycloalkylmethyl, tetrahydrofuran-2-on-3-yl, 3-halo-5-haloalkyl-2-pyridyl, (4), (5), (6) or (7); U is H, halogen, alkyl, and nitro; V is H, halogen; W is H, Na, amino, alkyl, and haloalkyl; X is O or S; Y is alkyl or haloalkyl; Z is H or halogen; R is halogen; R is haloalkoxy; R is alkyl; R is H or methyl; R is OH, ONa, OK, ONH4, O-alkylammonium, O-dialkylammonium, alkoxy, haloalkoxy, nitroalkoxy, cyanoalkoxy, propargyloxy, NH2, NH-phenyl, NHCH2Ph, N(alkyl)2, NH-alkyl, N(alkyl)(alkoxy), NH-alkynyl; NHCH2(halophenyl), NHCH2(nitrophenyl), NHSO2-alkyl, NHSO2-haloalkyl, NHSO2-phenyl, NHOCH2Ph, CH2SCN, S-alkyl, CH2S-alkyl, nitroalkoxy, OCH2Ph, OCH2CO2-alkyl, SCH2Ph, SCH2CO2-alkyl, cycloalkylalkoxy, or oxacycloalkylalkoxy; and R represents one or two substituents selected from alkyl, halogen, and nitro.
摘要翻译：公开了新颖的除草化合物，含有它们的组合物及其制备和用于控制杂草的方法。新型除草化合物为具有通式（1）的吲唑，其中Q为（2）或（3）; 烷基羰基，二烷基氨基羰基，卤代烷基羰基，烷基磺酰基，卤代烷基磺酰基，烷基氨基磺酰基，氰基硫代烷基羰基，二烷基氨基磺酰基，苯基烷基磺酰基，苯基烷基磺酰基，苯基烷基磺酰基，（4），（5），（6）或（7）所示的化合物，或其药学上可接受的盐。 U是H，卤素，烷基和硝基; V是H，卤素; W是H，Na，氨基，烷基和卤代烷基; X是O或S; Y是烷基或卤代烷基; Z是H或卤素; R是卤素; R 1是卤代烷氧基; R 2是烷基; R 3是H或甲基; R 4是OH，ONa，OK，ONH 4，O-烷基铵，O-二烷基铵，烷氧基，卤代烷氧基，硝基烷氧基，氰基烷氧基，炔丙氧基，NH 2，NH-苯基，NHCH 2 Ph，N（烷基）2，（烷基）（烷氧基），NH-炔基; NHCH2（卤代苯基），NHCH2（硝基苯基），NHSO2-烷基，NHSO2-卤代烷基，NHSO2-苯基，NHOCH2Ph，CH2SCN，S-烷基，CH2S-烷基，硝基烷氧基，OCH2Ph，OCH2CO2-烷基，SCH2Ph，SCH2CO2-烷基，环烷基烷氧基，或氧杂环烷基烷氧基; R 5表示选自烷基，卤素和硝基的一个或两个取代基。

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