专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2012125782A3 APPARATUS FOR OXYGENATION AND PERFUSION OF TISSUE FOR ORGAN PRESERVATION 审中-公开
公开(公告)号：WO2012125782A3
公开(公告)日：2012-09-20
申请号：PCT/US2012/029157
申请日：2012-03-15
申请人： PARAGONIX TECHNOLOGIES, INC. , JUDSON, Jared , MAIER, Lisa Maria
发明人： JUDSON, Jared , MAIER, Lisa Maria
IPC分类号： A01N1/02
摘要： An apparatus (10) according to an embodiment is configured to oxygenate and perfuse a bodily tissue (T) for extracorporeal preservation of the bodily tissue. The apparatus includes a pneumatic system, a pumping chamber (14), and an organ chamber (30). The pneumatic system is configured for the controlled delivery of fluid to and from the pumping chamber based on a predetermined control scheme. The pumping chamber is configured to diffuse a gas into a perfusate and to generate a pulse wave for moving the perfusate through the bodily tissue. The pumping chamber is configured to substantially automatically purge excess fluid from the pumping chamber to an area external to the apparatus. A semi -permeable membrane (20) is inclined from the first side (22) towards the second side (24) of the apparatus in order to direct a rising fluid towards a port (38) disposed at the highest portion of the pumping chamber.

2. 发明申请

WO2012125782A2 APPARATUS FOR OXYGENATION AND PERFUSION OF TISSUE FOR ORGAN PRESERVATION 审中-公开
标题翻译：用于组织保存的组织的氧化和吸收的装置
公开(公告)号：WO2012125782A2
公开(公告)日：2012-09-20
申请号：PCT/US2012029157
申请日：2012-03-15
申请人： PARAGONIX TECHNOLOGIES INC , JUDSON JARED , MAIER LISA MARIA
发明人： JUDSON JARED , MAIER LISA MARIA
IPC分类号： A01N1/02
CPC分类号： A01N1/0247 , A01N1/00 , A01N1/02 , A01N1/0236
摘要： An apparatus according to an embodiment is configured to oxygenate and perfuse a bodily tissue for extracorporeal preservation of the bodily tissue. The apparatus includes a pneumatic system, a pumping chamber, and an organ chamber. The pneumatic system is configured for the controlled delivery of fluid to and from the pumping chamber based on a predetermined control scheme. The predetermined control scheme can be, for example, a time-based control scheme or a pressure-based control scheme. The pumping chamber is configured to diffuse a gas into a perfusate and to generate a pulse wave for moving the perfusate through a bodily tissue. The organ chamber is configured to receive the bodily tissue and the perfusate. The organ chamber is configured to substantially automatically purge excess fluid from the organ chamber to the pumping chamber. The pumping chamber is configured to substantially automatically purge excess fluid from the pumping chamber to an area external to the apparatus.
摘要翻译：根据一个实施方案的装置被配置为对身体组织进行氧化和灌注以体外保存身体组织。该装置包括气动系统，泵送室和器官腔。气动系统构造成基于预定的控制方案来控制向泵送室输送流体。预定控制方案可以是例如基于时间的控制方案或基于压力的控制方案。泵送室被配置为将气体扩散到灌注液中并产生用于使灌注液通过身体组织移动的脉搏波。器官腔室构造成接收身体组织和灌注液。器官腔室构造成基本上自动地将多余的液体从器官腔排出到泵送室。泵送室被配置为基本上自动地将多余的流体从泵送室排出到设备外部的区域。

3. 发明申请

WO2006099569A3 METHODS AND COMPOSITIONS FOR BERYLLIUM-INDUCED DISEASE 审中-公开
标题翻译： BILLLLIUM诱发疾病的方法和组合
公开(公告)号：WO2006099569A3
公开(公告)日：2009-04-09
申请号：PCT/US2006009631
申请日：2006-03-13
申请人： NAT JEWISH MED & RES CENTER , FONTENOT ANDREW P , KOTZIN BRIAN L , NEWMAN LEE S , MAIER LISA
发明人： FONTENOT ANDREW P , KOTZIN BRIAN L , NEWMAN LEE S , MAIER LISA
IPC分类号： C12P21/04
CPC分类号： G01N33/6863 , G01N33/56972 , G01N2800/12 , G01N2800/24
摘要： The present invention provides for methods for detection, diagnosis and prognosis of beryllium-induced disease. In one embodiment, the methods include exposing immune cells from subjects suspected of having beryllium-induced disease to beryllium and assessing the Th-1 cytokines produced. Other embodiments include the use of exposing immune cells from subjects suspected of having beryllium-induced disease to beryllium and assessing Th-1 cytokines produced and using these assessments to indicate the stage of progression of the disease. Therapeutic methods involve assessing the onset or progression of beryllium-induced disease before during and after exposure to a treatment for the disease.
摘要翻译：本发明提供了铍诱发疾病的检测，诊断和预后的方法。在一个实施方案中，所述方法包括将怀疑患有铍诱发疾病的受试者的免疫细胞暴露于铍并评估产生的Th-1细胞因子。其他实施方案包括将怀疑患有铍诱发疾病的受试者的免疫细胞暴露于铍并评估所产生的Th1细胞因子并使用这些评估来指示疾病进展阶段的用途。治疗方法包括在暴露于该疾病的治疗之前和之后评估铍诱发的疾病的发作或进展。

4. 发明申请

WO2006099569A2 METHODS AND COMPOSITIONS FOR BERYLLIUM-INDUCED DISEASE 审中-公开
标题翻译： BILLLLIUM诱发疾病的方法和组合
公开(公告)号：WO2006099569A2
公开(公告)日：2006-09-21
申请号：PCT/US2006/009631
申请日：2006-03-13
申请人： NATIONAL JEWISH MEDICAL AND RESEARCH CENTER , FONTENOT, Andrew P. , KOTZIN, Brian L. , NEWMAN, Lee S. , MAIER, Lisa
发明人： FONTENOT, Andrew P. , KOTZIN, Brian L. , NEWMAN, Lee S. , MAIER, Lisa
IPC分类号： C12Q1/68
CPC分类号： G01N33/6863 , G01N33/56972 , G01N2800/12 , G01N2800/24
摘要： The present invention provides for methods for detection, diagnosis and prognosis of beryllium-induced disease. In one embodiment, the methods include exposing immune cells from subjects suspected of having beryllium-induced disease to beryllium and assessing the Th-1 cytokines produced. Other embodiments include the use of exposing immune cells from subjects suspected of having beryllium-induced disease to beryllium and assessing Th-1 cytokines produced and using these assessments to indicate the stage of progression of the disease. Therapeutic methods involve assessing the onset or progression of beryllium-induced disease before during and after exposure to a treatment for the disease.
摘要翻译：本发明提供了铍诱发疾病的检测，诊断和预后的方法。在一个实施方案中，所述方法包括将怀疑患有铍诱发疾病的受试者的免疫细胞暴露于铍并评估产生的Th-1细胞因子。其他实施方案包括将怀疑患有铍诱发疾病的受试者的免疫细胞暴露于铍并评估所产生的Th1细胞因子并使用这些评估来指示疾病进展阶段的用途。治疗方法包括在暴露于该疾病的治疗之前和之后评估铍诱发的疾病的发作或进展。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式