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1. 发明申请

WO2011139665A2 APPARATUS AND METHOD FOR EFFECTING AT LEAST ONE ANATOMICAL STRUCTURE 审中-公开
标题翻译：用于影响至少一种解剖结构的装置和方法
公开(公告)号：WO2011139665A2
公开(公告)日：2011-11-10
申请号：PCT/US2011/033875
申请日：2011-04-26
申请人： MACROPLATA, INC. , PISKUN, Gregory , GUTELIUS, Patrick , SHIKHMAN, Oleg
发明人： PISKUN, Gregory , GUTELIUS, Patrick , SHIKHMAN, Oleg
IPC分类号： A61B17/00 , A61B17/02 , A61B17/22 , A61B17/34 , A61B1/06
CPC分类号： A61B17/22031 , A61B1/06 , A61B17/02 , A61B17/12013 , A61B17/122 , A61B17/1285 , A61B17/3205 , A61B17/3421 , A61B18/1485 , A61B18/18 , A61B90/30 , A61B2017/3452 , A61B2018/005 , A61B2090/032
摘要： Exemplary embodiments of apparatus and method for effecting at least one anatomical structure of a body can be provided. For example, at least one first arrangement can be provided which is structured to be at least partially inserted into the body and including an opening. In addition, at least one second arrangement can be provided which configured to increase and/or decrease a size of the opening by a motion thereof in a first direction. Further, at least one third arrangement can be provided which can be coupled to the second arrangement(s), and configured to move at least in a second direction which is at least approximately parallel to the second direction. In particular, when the anatomical structure(s) is/are provided or inserted in the opening and is pressed on by the second arrangement(s), a first motion of the second arrangement(s) toward the anatomical structure(s) in the first direction is reduced and/or terminated while a second motion of the third arrangement(s) in the second direction either (i) remains at least approximately the same, and/or (ii) is reduced to a lesser extent than that of the first motion.
摘要翻译：可以提供用于实现身体的至少一个解剖结构的装置和方法的示例性实施例。例如，可以提供至少一个第一布置，其被构造成至少部分地插入到主体中并且包括开口。此外，可以提供至少一个第二布置，其构造成通过其在第一方向上的运动来增加和/或减小开口的尺寸。此外，可以提供至少一个第三布置，其可以耦合到第二布置，并且构造成至少在至少大致平行于第二方向的第二方向上移动。特别地，当解剖结构被提供或插入开口中并被第二装置按压时，第二装置朝向解剖结构的第一运动第一方向减少和/或终止，而第三方案在第二方向上的第二运动（i）保持至少大致相同，和/或（ii）减小到比第第一动议

2. 发明申请

WO2011084616A2 ARRANGEMENTS AND METHODS FOR EFFECTING AN ENDOLUMINAL ANATOMICAL STRUCTURE 审中-公开
标题翻译：用于影响内分泌解剖结构的安排和方法
公开(公告)号：WO2011084616A2
公开(公告)日：2011-07-14
申请号：PCT/US2010/060802
申请日：2010-12-16
申请人： MACROPLATA, INC. , PISKUN, Gregory , ROTTENBERG, Dan , MANASH, Boaz , PINHASOV, Dima
发明人： PISKUN, Gregory , ROTTENBERG, Dan , MANASH, Boaz , PINHASOV, Dima
IPC分类号： A61M25/10 , A61M25/01 , A61M29/02 , A61B17/22 , A61B1/04
CPC分类号： A61B1/32 , A61B1/00082 , A61B1/00085 , A61B1/00087 , A61B1/00089 , A61B1/00098 , A61B1/00154 , A61B1/0051 , A61B1/0125 , A61B1/018 , A61B1/04 , A61B1/31 , A61B17/00234 , A61B17/0218 , A61B17/12045 , A61B17/3423 , A61B2017/00296 , A61B2017/003 , A61B2017/0034 , A61B2017/00557 , A61B2017/0225 , A61B2017/12127 , A61B2017/345 , A61B2017/3452 , A61B2217/005 , A61M25/1011 , A61M29/02 , A61M2025/1052 , A61M2029/025
摘要： Exemplary embodiments of devices and method for affecting at least one anatomical tissue can be provided. A configuration can be provided that includes a structure which is expandable (i) having and/or (ii) forming at least one opening or a working space through which the anatomical tissue(s) is placed in the structure. For example, the structure, prior to being expanding, can have at least one partially rigid portion. In addition, or as an alternative, upon a partial or complete expansion thereof, the structure can be controllable to have a plurality of shapes. Further, the structure can be controllable to provide the working space with multiple shapes and/or multiple sizes.
摘要翻译：可以提供用于影响至少一个解剖组织的装置和方法的示例性实施例。可以提供一种构造，其包括可膨胀的结构（i）具有和/或（ii）形成至少一个开口或工作空间，通过该工作空间将解剖组织放置在结构中。例如，该结构在膨胀之前可以具有至少一个部分刚性部分。另外，或作为替代方案，在部分或完全扩展时，该结构可以被控制以具有多个形状。此外，该结构可以被控制以提供具有多种形状和/或多种尺寸的工作空间。

3. 发明申请

WO2011041578A2 DETACHABLE BALLOON CATHETER 审中-公开
标题翻译：可拆卸气球导管
公开(公告)号：WO2011041578A2
公开(公告)日：2011-04-07
申请号：PCT/US2010/050955
申请日：2010-09-30
申请人： MACROPLATA, INC. , PISKUN, Gregory , ROTTENBERG, Dan , MANASH, Boaz , PINHASOV, Dima
发明人： PISKUN, Gregory , ROTTENBERG, Dan , MANASH, Boaz , PINHASOV, Dima
IPC分类号： A61M25/10 , A61M39/26 , A61B1/31 , A61M25/16
CPC分类号： A61M25/10182 , A61B1/31 , A61M25/0097 , A61M25/10181 , A61M25/10185 , A61M29/02 , A61M39/14 , A61M39/26 , A61M2025/1052 , A61M2025/1054 , A61M2210/106
摘要： The disclosure relates to a device and method such as for treatment of a gastrointestinal perforation and a gastrointestinal bleeding. The device can be a balloon catheter that controls bleeding by pressing on a bleeding area or/and prevents the gastrointestinal contents trespassing outside a gastrointestinal lumen into a body cavity by blocking an opening in the luminal wall or blocking the colon distal or proximal to the perforation. The preferred device is inserted using an endoscope and allows to partially or completely withdraw an endoscope while leaving the balloon at the target area. The device and method can facilitate ceasing a colonic bleeding and blocking colonic perforation.
摘要翻译：本公开涉及一种装置和方法，例如用于治疗胃肠穿孔和胃肠道出血。该装置可以是气囊导管，其通过按压出血区域或/或通过阻塞腔壁中的开口或阻止结肠远端或近侧穿孔将胃肠内容物侵入胃肠内腔进入体腔，从而控制出血。优选的装置使用内窥镜插入，并且允许部分或全部地将内窥镜放回，同时将气囊留在目标区域。该装置和方法可以有助于停止结肠出血和阻塞结肠穿孔。

4. 发明申请

WO2016186876A1 TISSUE RETRACTOR FOR MINIMALLY INVASIVE SURGERY 审中-公开
标题翻译：用于微创外科手术的组织返回器
公开(公告)号：WO2016186876A1
公开(公告)日：2016-11-24
申请号：PCT/US2016/031355
申请日：2016-05-06
申请人： MACROPLATA, INC.
发明人： PISKUN, Gregory , TANG, Brian , RADZIUNAS, Jeffrey, Peter
IPC分类号： A61B17/02 , A61F2/966 , A61M29/00 , A61B17/00
CPC分类号： A61B17/0218 , A61B2017/00336 , A61B2017/0034 , A61B2017/00867 , A61B2017/0225
摘要： Improved methods and devices for performing an endoscopic surgery including a system for performing minimally invasive procedures including a flexible catheter having a working space expanding system positioned at a distal portion, the working space expanding system movable from a non-expanded insertion position to an expanded position forming an expanded region to expand the working space within the body lumen. A tissue retractor having an inner member positioned within an outer guide member has a plurality of closed loops at a distal portion forming a petal-like structure. The loops are positioned in a collapsed position within the outer guide member and are movable to an expanded position when exposed from the outer guide member.
摘要翻译：用于执行内窥镜手术的改进的方法和装置，包括用于执行微创手术的系统，包括具有位于远端部分的工作空间扩张系统的柔性导管，所述工作空间扩张系统可从非扩张插入位置移动到展开位置形成扩张区域以扩大体腔内的工作空间。具有定位在外引导构件内的内构件的组织牵缩器在形成花瓣状结构的远侧部分处具有多个闭合环。环被定位在外引导构件内的折叠位置，并且当从外引导构件露出时可以移动到扩展位置。

5. 发明申请

WO2016130442A1 SYSTEM FOR A MINIMALLY-INVASIVE, OPERATIVE GASTROINTESTINAL TREATMENT 审中-公开
标题翻译：微创手术治疗微创手术系统
公开(公告)号：WO2016130442A1
公开(公告)日：2016-08-18
申请号：PCT/US2016/016911
申请日：2016-02-06
申请人： MACROPLATA, INC.
发明人： PISKUN, Gregory , RADZIUNAS, Jeffrey, Peter , TO, John , FABRO, Mariel , TANG, Brian , KANTSEVOY, Sergey
IPC分类号： A61B17/02 , A61B1/00
CPC分类号： A61B1/00154 , A61B1/00066 , A61B1/00082 , A61B1/00085 , A61B1/00087 , A61B1/00135 , A61B1/018 , A61B1/31 , A61B1/32 , A61B17/00234 , A61B17/0218 , A61B17/1285 , A61B17/3421 , A61B2017/00269 , A61B2017/003 , A61B2017/00557 , A61B2017/00818 , A61B2017/0225 , A61B2017/345
摘要： Improved methods and devices for performing an endoscopic surgery including a system for performing minimally invasive procedures including a flexible catheter having a first lumen, a first flexible tube positioned in the first lumen, and a second flexible tube positioned in the first lumen. The first lumen defines a first space configured and dimensioned to receive an endoscope. The first flexible tube and second flexible tube are fixed at a proximal portion and configured to float within the first lumen of the catheter. First and second flexible guides are slidably positioned within the first and second flexible tubes and dimensioned to receive a first instrument for axial movement therein, the first and second flexible guides movable to an angled position with respect to a longitudinal axis. A working space expanding system positioned at a distal portion of the flexible catheter, the working space expanding system movable from a non- expanded insertion position to an expanded position forming an expanded region to expand the working space within the body lumen.
摘要翻译：用于执行内窥镜手术的改进的方法和装置，包括用于执行微创手术的系统，包括具有第一内腔的柔性导管，位于第一内腔中的第一柔性管和位于第一腔内的第二柔性管。第一腔限定构造和尺寸设计成接收内窥镜的第一空间。第一柔性管和第二柔性管固定在近端部分并且构造成在导管的第一内腔内浮动。第一和第二柔性引导件可滑动地定位在第一和第二柔性管内并且被设计成接收用于其中轴向运动的第一仪器，第一和第二柔性引导件可相对于纵向轴线移动到成角度的位置。位于所述柔性导管的远端部分的工作空间扩展系统，所述工作空间扩张系统可从非扩张插入位置移动到扩展位置，从而形成扩张区域，以使所述体腔内的工作空间膨胀。

6. 发明申请

WO2013062652A1 A GENTLE HEMORRHOID TREATMENT OFFERING A SUBSTANTIALLY PAINLESS HEALING 审中-公开
标题翻译：提供实质性无痛治疗的GENTLE HEMORRHOID治疗
公开(公告)号：WO2013062652A1
公开(公告)日：2013-05-02
申请号：PCT/US2012/049802
申请日：2012-08-06
申请人： MACROPLATA, INC. , PISKUN, Gregory , GUTELIUS, Patrick , SHIKHMAN, Oleg
发明人： PISKUN, Gregory , GUTELIUS, Patrick , SHIKHMAN, Oleg
IPC分类号： A61B18/04 , A61B17/03 , A61B17/12 , A61B17/94 , A61B1/31
CPC分类号： A61B1/31 , A61B1/00087 , A61B17/00234 , A61B17/12013 , A61B17/30 , A61B18/04 , A61B18/1442 , A61B18/1485 , A61B2017/00358 , A61B2017/3452 , A61B2018/005 , A61B2018/00589 , A61B2218/007
摘要： The teachings provided herein are directed to a methods and devices for treating a hemorrhoid in a subject in a manner that produces substantially less post-procedural pain in the subject, the method minimizing or avoiding a removing or a necrosis of a rectal tissue fold.
摘要翻译：本文提供的教导涉及用于在受试者中产生实质上较少的手术后疼痛的方式治疗受试者中的痔疮的方法和装置，所述方法最小化或避免直肠组织折叠的去除或坏死。

7. 发明申请

WO2011139665A3 APPARATUS AND METHOD FOR EFFECTING AT LEAST ONE ANATOMICAL STRUCTURE 审中-公开
标题翻译：用于影响至少一种解剖结构的装置和方法
公开(公告)号：WO2011139665A3
公开(公告)日：2012-04-19
申请号：PCT/US2011033875
申请日：2011-04-26
申请人： MACROPLATA INC , PISKUN GREGORY , GUTELIUS PATRICK , SHIKHMAN OLEG
发明人： PISKUN GREGORY , GUTELIUS PATRICK , SHIKHMAN OLEG
IPC分类号： A61B17/00 , A61B1/06 , A61B17/02 , A61B17/22 , A61B17/34
CPC分类号： A61B17/22031 , A61B1/06 , A61B17/02 , A61B17/12013 , A61B17/122 , A61B17/1285 , A61B17/3205 , A61B17/3421 , A61B18/1485 , A61B18/18 , A61B90/30 , A61B2017/3452 , A61B2018/005 , A61B2090/032
摘要： Exemplary embodiments of apparatus and method for effecting at least one anatomical structure of a body can be provided. For example, at least one first arrangement can be provided which is structured to be at least partially inserted into the body and including an opening. In addition, at least one second arrangement can be provided which configured to increase and/or decrease a size of the opening by a motion thereof in a first direction. Further, at least one third arrangement can be provided which can be coupled to the second arrangement(s), and configured to move at least in a second direction which is at least approximately parallel to the second direction. In particular, when the anatomical structure(s) is/are provided or inserted in the opening and is pressed on by the second arrangement(s), a first motion of the second arrangement(s) toward the anatomical structure(s) in the first direction is reduced and/or terminated while a second motion of the third arrangement(s) in the second direction either (i) remains at least approximately the same, and/or (ii) is reduced to a lesser extent than that of the first motion.
摘要翻译：可以提供用于实现身体的至少一个解剖结构的装置和方法的示例性实施例。例如，可以提供至少一个第一布置，其被构造成至少部分地插入到主体中并且包括开口。此外，可以提供至少一个第二布置，其构造成通过其在第一方向上的运动来增加和/或减小开口的尺寸。此外，可以提供至少一个第三布置，其可以耦合到第二布置，并且构造成至少在至少大致平行于第二方向的第二方向上移动。特别地，当解剖结构被提供或插入开口中并被第二装置按压时，第二装置朝向解剖结构的第一运动第一方向减少和/或终止，而第三方案在第二方向上的第二运动（i）保持至少大致相同，和/或（ii）减小到比第第一动议

8. 发明申请

WO2014200737A1 MULTI-LUMEN-CATHETER RETRACTOR SYSTEM FOR A MINIMALLY-INVASIVE, OPERATIVE GASTROINTESTINAL TREATMENT 审中-公开
标题翻译：用于微型入路，手术胃肠道治疗的多用途导管系统
公开(公告)号：WO2014200737A1
公开(公告)日：2014-12-18
申请号：PCT/US2014/040429
申请日：2014-06-01
申请人： MACROPLATA INC. , PISKUN, Gregory , TO, John , FABRO, Mariel , TANG, Brian , KANTSEVOY, Sergey
发明人： PISKUN, Gregory , TO, John , FABRO, Mariel , TANG, Brian , KANTSEVOY, Sergey
IPC分类号： A61B1/00 , A61B1/018 , A61B17/02 , A61B17/34 , A61B1/31 , A61B1/32 , A61B17/00
CPC分类号： A61B17/0218 , A61B17/00234 , A61B2017/00331 , A61B2017/00557 , A61B2017/0225 , A61B2017/345
摘要： A system for performing minimally invasive procedures in a body lumen of a patient including a flexible catheter having a first lumen configured and dimensioned to receive an endoscope therethrough and a second lumen configured and dimensioned to receive a first flexible tube therethrough. The first flexible tube is movable through the second lumen and has a distal portion including a first curve extending in a first direction with respect to the longitudinal axis and a second curve extending in a second different direction with respect to the longitudinal axis. A retractor system is positioned at a distal portion of the catheter and is movable from a non-expanded insertion position to an expanded position forming an expanded cage to form a larger working space. The distal portion of the first flexible tube is movable within the expanded cage.
摘要翻译：一种用于在患者的体腔中执行微创手术的系统，包括柔性导管，所述柔性导管具有构造和尺寸以便容纳内窥镜的第一腔，以及构造和尺寸设计成容纳穿过其中的第一柔性管的第二腔。第一柔性管可移动穿过第二内腔，并且具有包括相对于纵向轴线在第一方向上延伸的第一曲线的远侧部分和相对于纵向轴线沿第二不同方向延伸的第二曲线。牵开器系统定位在导管的远端部分处，并且可从非扩张插入位置移动到扩展位置，形成扩张笼以形成更大的工作空间。第一柔性管的远侧部分可在扩展的笼内移动。

9. 发明申请

WO2013192116A1 MULTI-LUMEN-CATHETER RETRACTOR SYSTEM FOR A MINIMALLY-INVASIVE, OPERATIVE GASTROINTESTINAL TREATMENT 审中-公开
标题翻译：用于微型入路，手术胃肠道治疗的多用途导管系统
公开(公告)号：WO2013192116A1
公开(公告)日：2013-12-27
申请号：PCT/US2013/046200
申请日：2013-06-17
申请人： MACROPLATA INC. , PISKUN, Gregory , TO, John , FABRO, Mariel , TANG, Brian , KANTSEVOY, Sergey
发明人： PISKUN, Gregory , TO, John , FABRO, Mariel , TANG, Brian , KANTSEVOY, Sergey
IPC分类号： A61B1/00 , A61B1/018 , A61B17/02 , A61B17/34
CPC分类号： A61B1/00087 , A61B1/00135 , A61B1/00154 , A61B1/31 , A61B17/0218 , A61B17/083 , A61B17/122 , A61B17/1285 , A61B17/3421 , A61B2017/00278 , A61B2017/00287 , A61B2017/00296 , A61B2017/00323 , A61B2017/00336 , A61B2017/00818 , A61B2017/00902 , A61B2017/2212 , A61B2017/2905 , A61B2017/3445 , A61B2017/3447 , A61B2017/345 , A61B2090/08021 , F04C2270/041
摘要： Improved methods and devices for performing an endoscopic surgery are provided. Systems are taught for operatively treating gastrointestinal disorders endoscopically in a stable, yet dynamic operative environment, and in a minimally-invasive manner. Such systems include, for example, an endoscopic surgical suite. The surgical suite can have a reversibly-expandable retractor that expands to provide a stable, operative environment within a subject. The expansion can be asymmetric around a stabilizer subsystem to maximize space for a tool and an endoscope to each be maneuvered independently to visualize a target tissue and treat the target tissue from outside the patient in a minimally invasive manner.
摘要翻译：提供了用于进行内窥镜手术的改进的方法和装置。所述系统被教导用于在稳定而又动态的手术环境中以微创方式内窥镜治疗胃肠道疾病。这样的系统包括例如内窥镜手术套件。外科手术套件可以具有可逆扩张的收缩器，其扩张以在受试者内提供稳定的手术环境。扩张可以在稳定器子系统周围是不对称的，以最大化工具和内窥镜的空间，每个人都可以独立地操纵以使目标组织可视化并且以微创方式从患者外部治疗目标组织。

10. 发明申请

WO2011084616A3 ARRANGEMENTS AND METHODS FOR EFFECTING AN ENDOLUMINAL ANATOMICAL STRUCTURE 审中-公开
标题翻译：影响内窥镜解剖结构的装置和方法
公开(公告)号：WO2011084616A3
公开(公告)日：2011-11-17
申请号：PCT/US2010060802
申请日：2010-12-16
申请人： MACROPLATA INC , PISKUN GREGORY , ROTTENBERG DAN , MANASH BOAZ , PINHASOV DIMA
发明人： PISKUN GREGORY , ROTTENBERG DAN , MANASH BOAZ , PINHASOV DIMA
IPC分类号： A61F2/958 , A61B1/04 , A61B17/22 , A61M25/01 , A61M29/02
CPC分类号： A61B1/32 , A61B1/00082 , A61B1/00085 , A61B1/00087 , A61B1/00089 , A61B1/00098 , A61B1/00154 , A61B1/0051 , A61B1/0125 , A61B1/018 , A61B1/04 , A61B1/31 , A61B17/00234 , A61B17/0218 , A61B17/12045 , A61B17/3423 , A61B2017/00296 , A61B2017/003 , A61B2017/0034 , A61B2017/00557 , A61B2017/0225 , A61B2017/12127 , A61B2017/345 , A61B2017/3452 , A61B2217/005 , A61M25/1011 , A61M29/02 , A61M2025/1052 , A61M2029/025
摘要： Exemplary embodiments of devices and method for affecting at least one anatomical tissue can be provided. A configuration can be provided that includes a structure which is expandable (i) having and/or (ii) forming at least one opening or a working space through which the anatomical tissue(s) is placed in the structure. For example, the structure, prior to being expanding, can have at least one partially rigid portion. In addition, or as an alternative, upon a partial or complete expansion thereof, the structure can be controllable to have a plurality of shapes. Further, the structure can be controllable to provide the working space with multiple shapes and/or multiple sizes.
摘要翻译：可以提供用于影响至少一个解剖组织的装置和方法的示例性实施例。可以提供一种构造，其包括可扩张的结构（i）具有和/或（ii）形成至少一个开口或工作空间，解剖组织通过该开口或工作空间放置在结构中。例如，该结构在膨胀之前可以具有至少一个部分刚性的部分。另外或者作为替代，在其部分或完全扩展时，该结构可以是可控的以具有多种形状。此外，该结构可以是可控的，以提供具有多种形状和/或多种尺寸的工作空间。

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