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1. 发明申请

WO2012118675A3 WETTABLE SILICONE HYDROGEL CONTACT LENSES 审中-公开
标题翻译：可湿式水胶接触镜
公开(公告)号：WO2012118675A3
公开(公告)日：2014-04-24
申请号：PCT/US2012026215
申请日：2012-02-23
申请人： COOPERVISION INT HOLDING CO LP , LIU YUWEN , CHEN CHARLIE , FRANCIS CHARLES A , GE JUNHAO , XU YUAN , YAO LI , BACK ARTHUR , ZHENG YING
发明人： LIU YUWEN , CHEN CHARLIE , FRANCIS CHARLES A , GE JUNHAO , XU YUAN , YAO LI , BACK ARTHUR , ZHENG YING
IPC分类号： C08G77/04 , G02C7/04
CPC分类号： G02C7/04 , B65B5/04 , G02B1/043 , C08L83/12 , C08L33/08 , C08L33/10
摘要： Ophthalmic ally acceptably wettable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (I): wherein m, n, R1 and R2 are as defined herein, the first siloxane monomer having a number average molecular weight of from 400 daltons to 700 daltons; and a second siloxane monomer having a number average molecular weight greater than 7,000 daltons; wherein a total amount of siloxane monomers present in the polymerizable composition is from 30 unit parts to 50 unit parts; the lenses also include units derived from at least one hydrophilic amide monomer having one N-vinyl group that is present in the polymerizable composition in an amount from 30 to 60 unit parts. The lenses have ophthalmically acceptably wettable lens surfaces when fully hydrated.
摘要翻译：描述了眼科盟友可接受的可湿性硅氧水凝胶隐形眼镜。透镜衍生自包含由式（I）表示的第一硅氧烷单体的可聚合组合物：其中m，n，R 1和R 2如本文所定义，第一硅氧烷单体的数均分子量为400道尔顿至700道尔顿 ; 和数均分子量大于7,000道尔顿的第二硅氧烷单体; 其中存在于聚合性组合物中的硅氧烷单体的总量为30单位份〜50单位份; 透镜还包括衍生自至少一种具有一个N-乙烯基的亲水性酰胺单体的单元，该单体存在于可聚合组合物中的量为30至60单位份。当完全水合时，镜片具有眼科可接受的可润湿透镜表面。

2. 发明申请

WO2012118674A2 SILICONE HYDROGEL CONTACT LENSES 审中-公开
标题翻译：硅胶水镜接触镜
公开(公告)号：WO2012118674A2
公开(公告)日：2012-09-07
申请号：PCT/US2012026214
申请日：2012-02-23
申请人： COOPERVISION INT HOLDING CO LP , YAO LI , HONG YE , LIU YUWEN , CHEN CHARLIE , FRANCIS CHARLES A , BACK ARTHUR
发明人： YAO LI , HONG YE , LIU YUWEN , CHEN CHARLIE , FRANCIS CHARLES A , BACK ARTHUR
IPC分类号： C08L43/04 , B65B55/02
CPC分类号： G02B1/043 , C08L83/12 , C08L101/14 , C08L33/10 , C08L33/08
摘要： Silicone hydrogel contact lenses that have good dimensional stability, are ophthalmically-acceptable, and can be manufactured without the use of alcohol solvents are formed from the reaction product of a polymerizable composition comprising at least one mono-functional acrylate-containing siloxane monomer having a molecular weight of less than 2,000; at least one bi-functional acrylate-containing siloxane monomer having a molecular weight of at least 3,000; and at least one hydrophilic vinyl-containing monomer, wherein the polymerizable composition has a molar ratio of total amount of mono- functional acrylate-containing siloxane monomer to total amount of bi-functional acrylate- containing siloxane monomer of at least 30:1, respectively.
摘要翻译：由可聚合组合物的反应产物形成具有良好的尺寸稳定性的眼科学可接受的硅胶水凝胶隐形眼镜，并且可以制造不含醇溶剂的可聚合组合物，该聚合性组合物包含至少一种含单分子丙烯酸酯的含有单官能丙烯酸酯的硅氧烷单体重量小于2000; 至少一种分子量至少为3,000的含二官能丙烯酸酯的硅氧烷单体; 和至少一种含亲水性含乙烯基的单体，其中所述可聚合组合物的含单体官能丙烯酸酯的硅氧烷单体的总量与含二官能丙烯酸酯的硅氧烷单体的总量的摩尔比分别为至少30:1 。

3. 发明申请

WO2012118685A3 SILICONE HYDROGEL CONTACT LENSES 审中-公开
标题翻译：硅胶水镜接触镜
公开(公告)号：WO2012118685A3
公开(公告)日：2014-04-24
申请号：PCT/US2012026230
申请日：2012-02-23
申请人： COOPERVISION INT HOLDING CO LP , LIU YUWEN , CHEN CHARLIE , GE JUNHAO , ZHENG YING , XU YUAN , YAO LI , BACK ARTHUR
发明人： LIU YUWEN , CHEN CHARLIE , GE JUNHAO , ZHENG YING , XU YUAN , YAO LI , BACK ARTHUR
IPC分类号： G02C7/04
CPC分类号： G02B1/043 , C08L51/085 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including 30-60 unit parts by weight of a hydrophilic monomer(s) having one N-vinyl group; 1 to 30 unit parts by weight of a first siloxane monomer component comprising a siloxane monomer of formula (1) as described herein or a siloxane monomer of formula (2) as described herein or a siloxane monomer of formula (3) as described herein or any combination thereof; and 10 to 39 unit parts by weight of a second siloxane monomer component comprising 3-[tris (trimethylsilyloxy) silyl] propyl methacrylate (TRIS), or MCS-M11, or both; where the polymerizable composition is free of &Ngr;,&Ngr;-dimethylacrylamide (DMA); and a total amount of siloxane monomers present in the polymerizable composition is from 15 to 40 unit parts by weight. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：描述了硅酮水凝胶隐形眼镜。透镜衍生自包含30-60单位重量份具有一个N-乙烯基的亲水性单体的可聚合组合物; 1至30单位重量份的包含本文所述的式（1）的硅氧烷单体的第一硅氧烷单体组分或如本文所述的式（2）的硅氧烷单体或本文所述的式（3）的硅氧烷单体或式其任何组合; 和10至39单位重量份的包含3- [三（甲硅烷基氧基）甲硅烷基]丙基丙烯酸酯（TRIS）或MCS-M11的第二硅氧烷单体组分或两者; 其中可聚合组合物不含N，N-二甲基丙烯酰胺（DMA）; 存在于聚合性组合物中的硅氧烷单体的总量为15〜40单位重量份。还描述了硅胶水凝胶隐形眼镜的批次和制备硅酮水凝胶隐形眼镜的方法。

4. 发明申请

WO2012118681A3 SILICONE HYDROGEL CONTACT LENSES HAVING ACCEPTABLE LEVELS OF ENERGY LOSS 审中-公开
标题翻译：具有可接受能量损失水平的SILICONE HYDROGEL接触镜
公开(公告)号：WO2012118681A3
公开(公告)日：2013-12-12
申请号：PCT/US2012026222
申请日：2012-02-23
申请人： COOPERVISION INT HOLDING CO LP , LIU RONGHUA , SHI XINFENG , LIU YUWEN , CHEN CHARLIE , HONG YE , FRANCIS CHARLES A , YAO LI , BACK ARTHUR , ZHENG YING
发明人： LIU RONGHUA , SHI XINFENG , LIU YUWEN , CHEN CHARLIE , HONG YE , FRANCIS CHARLES A , YAO LI , BACK ARTHUR , ZHENG YING
IPC分类号： G02C7/04
CPC分类号： G02C7/04 , G02B1/043 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses having ophthalmically acceptable levels of energy loss are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer which is a dual-end methacrylate end-capped polydimethylsiloxane having a number average molecular weight of at least 7,000 daltons. The average energy loss of the silicone hydrogel contact lenses is from about 30% to about 45% when the lenses are fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：描述了具有眼睛上可接受的能量损失水平的硅酮水凝胶隐形眼镜。透镜衍生自包含由式（1）表示的第一硅氧烷单体的可聚合组合物：其中式（1）的m表示3至10的一个整数，式（1）的n表示1至10的整数，R 1 式（1）的烷基是碳原子数为1〜4的烷基，式（1）的各R 2独立地为氢原子或甲基。透镜还包括衍生自第二硅氧烷单体的单元，其是数均分子量为至少7,000道尔顿的双末端甲基丙烯酸酯封端的聚二甲基硅氧烷。当透镜完全水合时，硅酮水凝胶隐形眼镜的平均能量损失为约30％至约45％。还描述了硅胶水凝胶隐形眼镜的批次和制备硅酮水凝胶隐形眼镜的方法。

5. 发明申请

WO2012154268A1 SILICONE HYDROGEL CONTACT LENSES 审中-公开
标题翻译：硅胶水镜接触镜
公开(公告)号：WO2012154268A1
公开(公告)日：2012-11-15
申请号：PCT/US2012/026225
申请日：2012-02-23
申请人： COOPERVISION INTERNATIONAL HOLDING COMPANY, LP , ZHENG, Ying , XU, Yuan , GE, Junhao , FRANCIS, Charles, A. , SUN, Yuan , LIU, Yuwen , CHEN, Charlie , HONG, Ye , QIU, Hongjin , YAO, Li , BACK, Arthur
发明人： ZHENG, Ying , XU, Yuan , GE, Junhao , FRANCIS, Charles, A. , SUN, Yuan , LIU, Yuwen , CHEN, Charlie , HONG, Ye , QIU, Hongjin , YAO, Li , BACK, Arthur
IPC分类号： C08F290/06
CPC分类号： B29D11/00125 , B29D11/0025 , C08F290/068 , G02B1/043 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including at least one siloxane monomer and at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer, or at least one hydrophilic vinyl ether-containing monomer, or both, wherein, when the at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, and when the at least one hydrophilic vinyl ethercontaining monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weighs are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：衍生自包含至少一种硅氧烷单体和至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体或至少一种亲水乙烯基醚的单体或两者的可聚合组合物的硅氧烷水凝胶隐形眼镜，其中当在在可聚合组合物中存在至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体，其存在量为1至20单位份重量，并且当在聚合性组合物中存在至少一种含亲水性乙烯基醚单体时，以1〜20个单位重量的量存在。还描述了硅胶水凝胶隐形眼镜的批次和制备硅酮水凝胶隐形眼镜的方法。

6. 发明申请

WO2012118684A2 SILICONE HYDROGEL CONTACT LENSES 审中-公开
标题翻译：硅胶水镜接触镜
公开(公告)号：WO2012118684A2
公开(公告)日：2012-09-07
申请号：PCT/US2012/026228
申请日：2012-02-23
申请人： COOPERVISION INTERNATIONAL HOLDING COMPANY, LP , LIU, Yuwen , HONG, Ye , GE, Junhao , XU, Yuan , CHEN, Charlie , FRANCIS, Charles, A. , YAO, Li , BACK, Arthur
发明人： LIU, Yuwen , HONG, Ye , GE, Junhao , XU, Yuan , CHEN, Charlie , FRANCIS, Charles, A. , YAO, Li , BACK, Arthur
IPC分类号： G02C7/04 , C08L51/08
CPC分类号： G02B1/043 , C08F226/00 , C08F236/20 , C08F283/065 , C08F283/126 , C08J11/02 , C08L51/085 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including a first siloxane monomer represented by formula (3): wherein m of formula (3) represents one integer from 3 to 10, n of formula (3) represents one integer from 1 to 10, R1 of formula (3) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (3) is independently either a hydrogen atom or a methyl group; and at least one vinyl ether-containing cross-linking agent are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described. In one example, the batches of silicone hydrogel contact lenses are dimensionally stable, and the method of making is a method of making dimensionally stable silicone hydrogel contact lenses.
摘要翻译：衍生自包含由式（3）表示的第一硅氧烷单体的聚合性组合物的聚合性组合物的硅氧水凝胶隐形眼镜：式（3）的m表示3〜10的整数，式（3）的n表示1〜 10，式（3）的R 1为碳原子数1〜4的烷基，式（3）的各R 2独立地为氢原子或甲基。和至少一种含乙烯基醚的交联剂。还描述了硅胶水凝胶隐形眼镜的批次和制备硅酮水凝胶隐形眼镜的方法。在一个示例中，硅胶水凝胶隐形眼镜的批次是尺寸稳定的，并且制造方法是制备尺寸稳定的硅酮水凝胶隐形眼镜的方法。

7. 发明申请

WO2012118678A1 WETTABLE SILICONE HYDROGEL CONTACT LENSES 审中-公开
标题翻译：可湿式水胶接触镜
公开(公告)号：WO2012118678A1
公开(公告)日：2012-09-07
申请号：PCT/US2012/026218
申请日：2012-02-23
申请人： COOPERVISION INTERNATIONAL HOLDING COMPANY, LP , HONG, Ye , YAO, Li , LIU, Yuwen , CHEN, Charlie , BACK, Arthur
发明人： HONG, Ye , YAO, Li , LIU, Yuwen , CHEN, Charlie , BACK, Arthur
IPC分类号： G02C7/04
CPC分类号： G02C7/049 , C08L83/12 , G02B1/043 , C08L101/14 , C08L83/04 , C08L51/085
摘要： Silicone hydrogel contact lenses are formed from the reaction product of a polymerizable composition comprising at least one acrylate-containing siloxane monomer, at least one hydrophilic vinyl-containing monomer, and at least one vinyl-containing cross-linking agent, wherein the polymerizable composition has a molar ratio of total amount of hydrophilic vinyl-containing monomer to total amount of acrylate-containing siloxane monomer of from 5:1 to 30:1, respectively. The silicone hydrogel contact lenses have good manufacturing processability, can be manufactured without the use of alcohol solvents, and have excellent surface wettability.
摘要翻译：硅氧烷水凝胶隐形眼镜由包含至少一种含丙烯酸酯的硅氧烷单体，至少一种亲水性含乙烯基单体和至少一种含乙烯基交联剂的可聚合组合物的反应产物形成，其中可聚合组合物具有亲水性含乙烯基单体的总量与含丙烯酸酯的硅氧烷单体的总量的摩尔比分别为5:1至30:1。硅酮水凝胶隐形眼镜具有良好的制造加工性，可以在不使用醇溶剂的情况下制造，并且具有优异的表面润湿性。

8. 发明申请

WO2012118670A2 SILICONE HYDROGEL CONTACT LENSES AND RELATED COMPOSITIONS AND METHODS 审中-公开
标题翻译：硅胶水凝胶接触镜及相关组合物及方法
公开(公告)号：WO2012118670A2
公开(公告)日：2012-09-07
申请号：PCT/US2012/026210
申请日：2012-02-23
申请人： COOPERVISION INTERNATIONAL HOLDING COMPANY, LP , LIU, Yuwen , CHEN, Charlie , HONG, Ye , FRANCIS, Charles, A. , YAO, Li , BACK, Arthur
发明人： LIU, Yuwen , CHEN, Charlie , HONG, Ye , FRANCIS, Charles, A. , YAO, Li , BACK, Arthur
IPC分类号： B65B55/02 , G02C7/04
CPC分类号： G02B1/043 , B65B55/02 , C08L101/14 , C08L83/04 , C08L51/085
摘要： Silicone hydrogel contact lenses are produced without using volatile organic solvents to extract materials from the polymerized contact lens bodies, and instead are washed with aqueous liquids. The silicone hydrogel contact lenses so produced have ophthalmically wettable lens surfaces. The hydrated silicone hydrogel contact lenses have diameters that are at least 24% larger than the diameters of the silicone hydrogel contact lenses prior to hydration or washing.
摘要翻译：制造硅氧烷水凝胶隐形眼镜，而不使用挥发性有机溶剂从聚合的隐形眼镜体提取物质，而是用含水液体洗涤。如此生产的硅酮水凝胶隐形眼镜具有眼睛可润湿的透镜表面。水合硅酮水凝胶隐形眼镜的直径比水合或洗涤前的硅酮水凝胶隐形眼镜的直径大至少24％。

9. 发明申请

WO2012021337A2 TECHNIQUES FOR ALLOCATION OF CONTROL CHANNELS 审中-公开
标题翻译：分配控制信道的技术
公开(公告)号：WO2012021337A2
公开(公告)日：2012-02-16
申请号：PCT/US2011/046314
申请日：2011-08-02
申请人： INTEL CORPORATION , WANG, Ping , LIU, Yuwen
发明人： WANG, Ping , LIU, Yuwen
IPC分类号： H04J11/00 , H04B7/26 , H04W72/04
CPC分类号： H04L5/001 , H04B17/318 , H04L5/0039 , H04L5/0053 , H04L5/0073 , H04L5/0085 , H04L5/0098 , H04W72/0406 , Y02D70/126
摘要： Techniques are described for setting the Physical Downlink Control Channel search spaces for component carriers. If any component carrier is de-activated, the Carrier Indicator Fields (CIF) of remaining activated component carriers can be set to consecutive values. The User Element can utilize its identifier to determine the starting point Control Channel Elements in each subframe. The locations of Control Channel Elements for a component carrier can be determined based on its CIF. Accordingly, search spaces for different component carriers can potentially be closely spaced but not overlap.
摘要翻译：描述了用于为分量载波设置物理下行链路控制信道搜索空间的技术。如果任何分量载波被禁用，则剩余的激活分量载波的载波指示符字段（CIF）可被设置为连续值。用户单元可以利用其标识符来确定每个子帧中的起始点控制信道单元。分量载波的控制信道单元的位置可以根据其CIF来确定。因此，不同分量载波的搜索空间可能会被紧密隔开但不会重叠。

10. 发明申请

WO2012118676A3 HIGH WATER CONTENT SILICONE HYDROGEL CONTACT LENSES 审中-公开
标题翻译：高含水硅胶接触镜
公开(公告)号：WO2012118676A3
公开(公告)日：2014-04-24
申请号：PCT/US2012026216
申请日：2012-02-23
申请人： COOPERVISION INT HOLDING CO LP , LIU YUWEN , CHEN CHARLIE , HONG YE , FRANCIS CHARLES A , YAO LI , BACK ARTHUR
发明人： LIU YUWEN , CHEN CHARLIE , HONG YE , FRANCIS CHARLES A , YAO LI , BACK ARTHUR
IPC分类号： C08G77/04 , G02C7/04
CPC分类号： G02B1/043 , C08F283/065 , C08L51/085 , C08L101/14
摘要： Silicone hydrogel contact lenses having a high water content are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer having a number average molecular weight of at least 7,000 daltons, and at least one vinyl- containing cross-linking agent. The lenses have average equilibrium water contents from about 30% wt/wt to about 70% wt/wt when fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：描述了具有高水含量的硅氧烷水凝胶隐形眼镜。透镜衍生自包含由式（1）表示的第一硅氧烷单体的可聚合组合物：其中式（1）的m表示3至10的一个整数，式（1）的n表示1至10的整数，R 1 式（1）的烷基是碳原子数为1〜4的烷基，式（1）的各R 2独立地为氢原子或甲基。透镜还包括衍生自数均分子量为至少7,000道尔顿的第二硅氧烷单体的单元和至少一种含乙烯基交联剂。当完全水合时，透镜具有约30重量％至约70重量％的平均水含量。还描述了硅胶水凝胶隐形眼镜的批次和制备硅酮水凝胶隐形眼镜的方法。

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