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1. 发明申请

WO2003089583A2 TISSUE SPECIFIC GENES AND GENE CLUSTERS 审中-公开
标题翻译：组织特定基因和基因簇
公开(公告)号：WO2003089583A2
公开(公告)日：2003-10-30
申请号：PCT/US2003/011497
申请日：2003-04-15
申请人： ORIGENE TECHNOLOGIES, INC. , JAY, Gilbert , LEBOVITZ, Richard, M. , LIU, Xuan , SHU, Youmin , SUN, Zairen , WU, Meng
发明人： JAY, Gilbert , LEBOVITZ, Richard, M. , LIU, Xuan , SHU, Youmin , SUN, Zairen , WU, Meng
IPC分类号： C12N
CPC分类号： C12Q1/6881 , A61K38/00 , C07K14/723 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158
摘要： The present invention relates to genes and genes clusters which are expressed in a tissue specific manner. For example, the invention relates to a group of genes encoding GPCR-like receptors that are involved in the function and activity of the immune system. These genes are organized into a discrete cluster at chromosomal location 1q22 (the “immune gene complex”) and span about 700 kb of DNA. The region closest to the centromere comprises genes that are expressed predominantly in the thymus, while the distal region comprises genes which are expressed predominantly in the bone marrow and other hematopoietic cells. Another cluster of GPCR genes is located at chromosomal band 11q24. These genes are expressed predominantly in pancreatic tissue, establishing this region of chromosome 11 as a unique gene complex involved in pancreatic function. A cluster of transmembrane and GPCR-type receptor genes is also located at chromosomal band 11q12.2. These genes are expressed predominantly in the spleen (hence, “spleen gene” cluster), as well as other tissues of the immune and reticuloendothelial system (RES), indicating that establishing this region of the chromosome is involved is spleen, lymphoid, and/or reticuloendothelial function. Finally, genes coding for membrane proteins have been identified which are expressed selectively in bone marrow, kidney, pancreas, and retina.
摘要翻译：本发明涉及以组织特异性方式表达的基因和基因簇。例如，本发明涉及编码参与免疫系统的功能和活性的GPCR样受体的一组基因。这些基因被组织成染色体位置1q22（“免疫基因复合体”）并跨越约700kb DNA的离散簇。最靠近着丝粒的区域包括主要在胸腺中表达的基因，而远端区域包含主要在骨髓和其他造血细胞中表达的基因。另一组GPCR基因位于染色体条带11q24。这些基因主要在胰腺组织中表达，将该染色体11区域作为涉及胰腺功能的独特基因复合体。跨膜和GPCR型受体基因簇也位于染色体条带11q12.2。这些基因主要在脾脏（因此，“脾基因”簇）以及免疫和网状内皮系统（RES）的其他组织中表达，表明建立该染色体区域是脾，淋巴和/ 或网状内皮功能。最后，已经鉴定了编码膜蛋白的基因，其在骨髓，肾，胰腺和视网膜中选择性表达。

2. 发明申请

WO2019196026A1 FLEXIBLE CONDUCTOR FOR DISCONNECTOR AND THE DISCONNECTOR THEREOF 审中-公开
公开(公告)号：WO2019196026A1
公开(公告)日：2019-10-17
申请号：PCT/CN2018/082621
申请日：2018-04-11
申请人： ABB SCHWEIZ AG , YAN, Jiaquan , LI, Shengqiang , LI, Bingle , WANG, Delong , LIU, Xuan
发明人： YAN, Jiaquan , LI, Shengqiang , LI, Bingle , WANG, Delong , LIU, Xuan
IPC分类号： H01H31/02 , H01H31/00 , H01H1/42
摘要： Embodiments of the present disclosure provide a flexible conductor for connecting a main blade and a base of a disconnector. The flexible conductor comprises a first portion and a second portion, the first portion is fixed to the base and adapted to bend in a first plane in response to a rotation of the main blade about a first axis; and the second portion is connected to the first portion and fixed to the main blade, the second portion adapted to bend in a second plane substantially perpendicular to the first plane in response to twisting of the main blade about a second axis; wherein the flexible conductor is operable to maintain an electrical connection between the main blade and the base when the main blade rotates and twists with respect to the base to open or close the disconnector. In this way, the flexible conductor can maintain an electrical connection between the main blade and the base steadily and durably when opening or closing the disconnector.

3. 发明申请

WO2012174729A1 PROCESS FOR PREPARING VINYL ESTERS OF TERTIARY CARBOXYLIC ACIDS 审中-公开
标题翻译：制备仲羧酸的乙烯酯的方法
公开(公告)号：WO2012174729A1
公开(公告)日：2012-12-27
申请号：PCT/CN2011/076241
申请日：2011-06-24
申请人： THE SOUTHWEST RESEARCH & DESIGN INSTITUTE OF CHEMICAL INDUSTRY , CELANESE INTERNATIONAL CORPORATION , WANG, Hang , LAI, Chongwei , ZENG, Jian , JIA, Huiru , LIAO, Jiong , LIU, Xuan , MAO, Zhenbo , JI, Chengzhu , JIANG, Guizhong , CHEN, Xiaohua
发明人： WANG, Hang , LAI, Chongwei , ZENG, Jian , JIA, Huiru , LIAO, Jiong , LIU, Xuan , MAO, Zhenbo , JI, Chengzhu , JIANG, Guizhong , CHEN, Xiaohua
IPC分类号： C07C67/04 , C07C69/01
CPC分类号： C07C67/04 , C07C69/24
摘要： A process for preparing vinyl esters of tertiary carboxylic acids by liquid phase addition of acetylene and tertiary carboxylic acids in the presence of metal salts of the tertiary carboxylic acids is disclosed. By subjecting the catalyst into a pre-activation and controlling the per pass conversation rate of free tertiary carboxylic acid during the reaction, the activity of catalyst, the selectivity of tertiary carboxylic acid for vinyl ester thereof, the per pass conversion rate of acetylene, and/or the selectivity of acetylene for vinyl ester of the tertiary carboxylic acid are improved.
摘要翻译：公开了在叔羧酸的金属盐存在下通过乙炔和叔羧酸的液相加成制备叔羧酸的乙烯基酯的方法。通过使催化剂进行预活化并控制反应期间游离叔羧酸的每次通过速率，催化剂的活性，叔羧酸对其乙烯基酯的选择性，乙炔的通过转化率和乙炔对叔羧酸的乙烯基酯的选择性提高。

4. 发明申请

WO2012018832A2 AUTOMATIC CALIBRATION OF FOURIER-DOMAIN OPTICAL COHERENCE TOMOGRAPHY SYSTEMS 审中-公开
标题翻译：傅里叶域光学相干层析成像系统的自动标定
公开(公告)号：WO2012018832A2
公开(公告)日：2012-02-09
申请号：PCT/US2011/046290
申请日：2011-08-02
申请人： THE JOHNS HOPKINS UNIVERSITY , KANG, Jin , BALICKI, Marcin Arkadiusz , LIU, Xuan
发明人： KANG, Jin , BALICKI, Marcin Arkadiusz , LIU, Xuan
IPC分类号： A61B17/94 , G01B9/02 , G06F19/00
CPC分类号： G01B9/02091 , G01B9/02044 , G01B9/02074 , G01N21/4795
摘要： A method for calibrating a Fourier domain optical coherence tomography system includes receiving spectral data from an optical detector comprising a linear array of detector elements, each detector element having a position labeled n, wherein detected light was wavelength-dispersed across the linear array of detector elements; determining parameters of a preselected functional relationship between wave number, kn, corresponding to detector element n as a function of optical detector element n based on the spectral data; further receiving subsequent spectral data subsequent to the first-mentioned receiving, wherein detected light was wavelength-dispersed across the linear array of detector elements; converting the subsequent spectral data using the preselected functional relationship between wave number kn and optical detector element n to obtain converted spectral data; and performing an inverse Fourier transform of the converted spectral data to obtain a depth profile.
摘要翻译：一种用于校准傅里叶域光学相干断层分析系统的方法包括：从包括检测器元件的线性阵列的光学检测器接收光谱数据，每个检测器元件具有标记为n的位置，其中检测到的光是波长相关的，分散在检测器元件的线性阵列上; 基于光谱数据确定作为光学检测器元件n的函数的对应于检测器元件n的波数kn之间的预选函数关系的参数; 进一步接收在首次提到的接收之后的后续光谱数据，其中检测到的光在检测器元件的线性阵列上波长分散; 使用波数kn与光学检测器元件n之间的预选函数关系转换随后的光谱数据以获得转换的光谱数据; 并且对转换后的光谱数据进行傅立叶逆变换以获得深度分布。

5. 发明申请

WO2003089583A3 TISSUE SPECIFIC GENES AND GENE CLUSTERS 审中-公开
公开(公告)号：WO2003089583A3
公开(公告)日：2003-10-30
申请号：PCT/US2003/011497
申请日：2003-04-15
申请人： ORIGENE TECHNOLOGIES, INC. , JAY, Gilbert , LEBOVITZ, Richard, M. , LIU, Xuan , SHU, Youmin , SUN, Zairen , WU, Meng
发明人： JAY, Gilbert , LEBOVITZ, Richard, M. , LIU, Xuan , SHU, Youmin , SUN, Zairen , WU, Meng
IPC分类号： C12N15/11
摘要： The present invention relates to genes and genes clusters which are expressed in a tissue specific manner. For example, the invention relates to a group of genes encoding GPCR-like receptors that are involved in the function and activity of the immune system. These genes are organized into a discrete cluster at chromosomal location 1q22 (the “immune gene complex”) and span about 700 kb of DNA. The region closest to the centromere comprises genes that are expressed predominantly in the thymus, while the distal region comprises genes which are expressed predominantly in the bone marrow and other hematopoietic cells. Another cluster of GPCR genes is located at chromosomal band 11q24. These genes are expressed predominantly in pancreatic tissue, establishing this region of chromosome 11 as a unique gene complex involved in pancreatic function. A cluster of transmembrane and GPCR-type receptor genes is also located at chromosomal band 11q12.2. These genes are expressed predominantly in the spleen (hence, “spleen gene” cluster), as well as other tissues of the immune and reticuloendothelial system (RES), indicating that establishing this region of the chromosome is involved is spleen, lymphoid, and/or reticuloendothelial function. Finally, genes coding for membrane proteins have been identified which are expressed selectively in bone marrow, kidney, pancreas, and retina.

6. 发明申请

WO2018023723A1 DISCONNECTOR AND MANUFACTURING METHOD 审中-公开
标题翻译：断路器和制造方法
公开(公告)号：WO2018023723A1
公开(公告)日：2018-02-08
申请号：PCT/CN2016/093575
申请日：2016-08-05
申请人： ABB SCHWEIZ AG , LIU, Xuan , CHEN, Rui , YAN, Jiaquan , LV, Zhangang
发明人： LIU, Xuan , CHEN, Rui , YAN, Jiaquan , LV, Zhangang
IPC分类号： H01H31/36
摘要： A disconnector(100) and a method for manufacturing the disconnector (100) are disclosed. The disconnector (100) includes conductive arms (110) pivotally coupled with each other, and finger contacts (111). The finger contacts (111) have two opposite ends (115, 116) and an elastic portion (113) between the two opposite ends (115, 116), each of the finger contacts (111) being fixed to the respective conductive arm (110) by fasteners (112) at the two opposite ends (115, 116) such that the elastic portion (113) presses against the conductive arm (110). In response to the conductive arms (110) being pivoted toward each other and clamping an electrical contact (200) hanged at a bus-bar above the disconnector (100), the conductive arms (110) are electrically coupled with the electrical contact (200) via the respective finger contacts (111). The disconnector (100) according to the present disclosure provides outstanding contact performances while the material costs as well as manufacturing and assembly costs are relatively low.
摘要翻译：公开了一种隔离开关（100）和用于制造隔离开关（100）的方法。断路器（100）包括彼此枢转地联接的导电臂（110）以及手指触点（111）。手指触点（111）具有两个相对的端部（115,116）和位于两个相对端部（115,116）之间的弹性部分（113），每个手指触点（111）固定到相应的导电臂（110 ）通过在两个相对端（115,116）处的紧固件（112）使得弹性部分（113）压靠导电臂（110）。响应于导电臂（110）朝向彼此枢转并夹紧悬挂在隔离开关（100）上方的母线处的电触头（200），导电臂（110）与电触头（200）电耦合）通过相应的手指触点（111）。根据本公开的隔离开关（100）提供了出色的接触性能，同时材料成本以及制造和组装成本相对较低。

7. 发明申请

WO2016119147A1 MECHANICAL INTERLOCK ASSEMBLY FOR DISCONNECTOR AND EARTHING SWITCH 审中-公开
标题翻译：用于断路器和接地开关的机械互锁组件
公开(公告)号：WO2016119147A1
公开(公告)日：2016-08-04
申请号：PCT/CN2015/071761
申请日：2015-01-28
申请人： ABB TECHNOLOGY LTD , CHEN, Rui , YUAN, Zhipeng , LIU, Xuan , YAN, Jiaquan
发明人： CHEN, Rui , YUAN, Zhipeng , LIU, Xuan , YAN, Jiaquan
IPC分类号： H01H9/26
CPC分类号： H01H9/24 , H01H3/46 , H01H9/26 , H01H31/003 , H01H31/08 , H01H31/10 , H01H31/28 , H01H31/32 , H01H33/42
摘要： A mechanical interlock assembly for a disconnector and an earthing switch is provided. It comprises: a main interlock disc (172) configured to actuate a movable contact of a disconnector (11), and at least one earthing switch interlock disc (173, 173') configured to actuate respective movable contact of at least one earthing switch (12, 13) respectively. The main interlock disc (172) is provided with at least one first groove (1721), and each of the at least one earthing switch interlock disc (173, 173') is provided with a third groove (1731), and it is provided with a movable interlock pin (174) between the main interlock disc (172) and each earthing switch interlock disc (173, 173') respectively. This interlock assembly can interlock the disconnector and the at least one earthing switch, and has the advantages of a simple structure, low cost and flexibility for different arrangements. A further mechanical interlock assembly is also provided to interlock another disconnector and one of the above at least one earthing switch.
摘要翻译：提供了用于隔离开关和接地开关的机械联锁组件。它包括：构造成致动断路器（11）的可动触点的主互锁盘（172）和被配置为致动至少一个接地开关的相应可动触点的至少一个接地开关互锁盘（173,173'） 12,13）。主互锁盘172设置有至少一个第一凹槽，并且至少一个接地开关互锁盘173,173'中的每一个设置有第三凹槽1731）在主互锁盘（172）和每个接地开关互锁盘（173,173'）之间分别具有可动互锁销（174）。该联锁组件可以互锁隔离开关和至少一个接地开关，并且具有结构简单，成本低，灵活性好的优点。还提供另一机械互锁组件以互锁另一隔离开关和上述至少一个接地开关中的一个。

8. 发明申请

WO2012072356A1 HAZARD DETECTION FOR ASSET MANAGEMENT 审中-公开
标题翻译：资产管理危害检测
公开(公告)号：WO2012072356A1
公开(公告)日：2012-06-07
申请号：PCT/EP2011/069138
申请日：2011-10-31
申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION , FENHAGEN IV, Frank, Donald , CULP, James, Robert , LIU, Xuan , HAMPAPUR, Arun , PANKANTI, Sharathchandra, Umapathirao
发明人： FENHAGEN IV, Frank, Donald , CULP, James, Robert , LIU, Xuan , HAMPAPUR, Arun , PANKANTI, Sharathchandra, Umapathirao
IPC分类号： G06Q90/00
CPC分类号： G06K9/00476 , G06K9/0063 , G06K9/52 , G06Q10/06311 , G06Q90/00 , G06T7/30 , G06T11/60 , G06T2207/10032 , G06T2207/30184
摘要： An approach that detects locations of hazardous conditions within an infrastructure is provided. This approach uses satellite imagery, GIS data, automatic image processing, and predictive modeling to determine the location of the hazards automatically, thus optimizing infrastructure management. Specifically, a hazard detection tool provides this capability. The hazard detection tool comprises a detection component configured to: receive visual media containing asset location data about a set of physical assets, and hazard location data about potential hazards within a vicinity of each of the set of physical assets. The detection component further receives graphical information system (GIS) data containing asset location data about each of the set of physical assets. The hazard detection tool further comprises an analysis component configured to: analyze the visual media to determine if a hazardous condition exists for each of the set of physical assets; and apply the GIS data to the visual media to determine a location of hazardous conditions within the infrastructure.
摘要翻译：提供了一种检测基础设施内危险状况位置的方法。这种方法使用卫星图像，GIS数据，自动图像处理和预测建模来自动确定危害位置，从而优化基础设施管理。具体来说，危害检测工具提供了这一功能。所述危险检测工具包括检测部件，所述检测部件被配置为：接收包含关于一组物理资产的资产位置数据的视觉媒体，以及关于所述一组物理资产附近的潜在危险的危险位置数据。检测组件还接收关于每组物理资产的资产位置数据的图形信息系统（GIS）数据。所述危险检测工具还包括分析部件，其被配置为：分析所述视觉介质以确定所述一组物理资产中是否存在危险状况; 并将GIS数据应用于视觉媒体，以确定基础设施内危险状况的位置。

9. 发明申请

WO2017116840A1 METHODS FOR THE PRODUCTION OF FERMENTATION PRODUCTS FROM FEEDSTOCK 审中-公开
标题翻译：从原料生产发酵产物的方法
公开(公告)号：WO2017116840A1
公开(公告)日：2017-07-06
申请号：PCT/US2016/067727
申请日：2016-12-20
申请人： DANISCO US INC. , DUAN, Gang , GOHEL, Vipul , LIU, Xuan , QIAN, Ying , RANGANATHAN, Kannan , ZHANG, Xiaoping
发明人： DUAN, Gang , GOHEL, Vipul , LIU, Xuan , QIAN, Ying , RANGANATHAN, Kannan , ZHANG, Xiaoping
IPC分类号： C12P19/00 , C12P7/06 , C12P7/08 , C12P7/10
CPC分类号： C12P7/06 , C12P7/08 , C12P7/10 , C12P19/00 , Y02E50/16 , Y02E50/17
摘要： Methods and compositions for enhanced production of at least one fermentation product resulting from the fermentation of sugar containing medium obtained from one or more feedstocks are disclosed herein. The compositions disclosed herein comprise trehalase.
摘要翻译：本文公开了用于增强生产由从一种或多种原料获得的含糖培养基的发酵产生的至少一种发酵产物的方法和组合物。本文公开的组合物包含海藻糖酶。

10. 发明申请

WO2012018832A3 AUTOMATIC CALIBRATION OF FOURIER-DOMAIN OPTICAL COHERENCE TOMOGRAPHY SYSTEMS 审中-公开
标题翻译： FOURIER-DOMAIN光学相干系统的自动校准
公开(公告)号：WO2012018832A3
公开(公告)日：2012-05-24
申请号：PCT/US2011046290
申请日：2011-08-02
申请人： UNIV JOHNS HOPKINS , KANG JIN , BALICKI MARCIN ARKADIUSZ , LIU XUAN
发明人： KANG JIN , BALICKI MARCIN ARKADIUSZ , LIU XUAN
IPC分类号： A61B17/94 , G01B9/02 , G06F19/00
CPC分类号： G01B9/02091 , G01B9/02044 , G01B9/02074 , G01N21/4795
摘要： A method for calibrating a Fourier domain optical coherence tomography system includes receiving spectral data from an optical detector comprising a linear array of detector elements, each detector element having a position labeled n, wherein detected light was wavelength-dispersed across the linear array of detector elements; determining parameters of a preselected functional relationship between wave number, kn, corresponding to detector element n as a function of optical detector element n based on the spectral data; further receiving subsequent spectral data subsequent to the first-mentioned receiving, wherein detected light was wavelength-dispersed across the linear array of detector elements; converting the subsequent spectral data using the preselected functional relationship between wave number kn and optical detector element n to obtain converted spectral data; and performing an inverse Fourier transform of the converted spectral data to obtain a depth profile.
摘要翻译：用于校准傅立叶域光学相干断层摄影系统的方法包括从包括检测器元件的线性阵列的光学检测器接收光谱数据，每个检测器元件具有标记为n的位置，其中检测到的光被波长分散在检测器元件的线性阵列 ; 基于光谱数据确定与检测器元件n对应的波数kn的预选函数关系的参数作为光学检测器元件n的函数; 进一步接收在所述第一次接收之后的随后的光谱数据，其中检测的光被波长分散在检测器元件的线性阵列上; 使用波数kn和光检测器元件n之间的预选功能关系来转换随后的光谱数据，以获得转换的光谱数据; 并对所转换的光谱数据执行逆傅立叶变换以获得深度分布。

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