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1. 发明申请

WO2007053297A2 METHODS FOR IMPROVING THE HYDROPHILICITY OF CONTACT LENSES AND CONTACT LENSES HAVING THE SAME 审中-公开
标题翻译：提高接触镜和亲水镜的亲水性的方法
公开(公告)号：WO2007053297A2
公开(公告)日：2007-05-10
申请号：PCT/US2006/040610
申请日：2006-10-17
申请人： SYNERGEYES, INC. , BENRASHID, Ramezan , LEGERTON, Jerome, A. , DAHI, Ali
发明人： BENRASHID, Ramezan , LEGERTON, Jerome, A. , DAHI, Ali
CPC分类号： G02C7/049 , G02B1/043 , G02C2202/16 , C08L43/04 , C08L83/04
摘要： The present invention relates to contact lenses manufactured using a gas permeable material with improved hydrophilicity. A method for improving the hydrophilicity of the contact lens includes providing a contact lens comprising a gas permeable contact lens material and exposing the material to a treatment solution comprising a chemical agent under conditions that are effective to significantly reduce the contact angle of the contact lens for a period of at least about two months. In another embodiment, the method includes irradiating the contact lens to sterilize the contact lens material. A contact lens manufactured using this method includes a substantially rigid portion comprising a polymeric material, the polymeric material comprising a hydrophilic surface having a contact angle of about 65 degrees or less.
摘要翻译：本发明涉及使用具有改善的亲水性的透气材料制造的隐形眼镜。提高隐形眼镜亲水性的方法包括提供一种包括透气隐形眼镜材料的隐形眼镜，并将该材料暴露于包含化学药剂的治疗溶液中，该条件有效地显着降低隐形眼镜的接触角，至少约两个月的时间。在另一个实施例中，该方法包括照射隐形眼镜以对隐形眼镜材料进行消毒。使用该方法制造的隐形眼镜包括包含聚合物材料的基本刚性部分，所述聚合物材料包含接触角为约65度或更小的亲水性表面。

2. 发明申请

WO2006026666A3 MULTIPURPOSE OPTICAL IMAGING DEVICES 审中-公开
标题翻译：多用途光学成像装置
公开(公告)号：WO2006026666A3
公开(公告)日：2006-07-06
申请号：PCT/US2005030969
申请日：2005-08-31
申请人： SYNERGEYES INC , SCHWIEGERLING JIM , LEGERTON JEROME A
发明人： SCHWIEGERLING JIM , LEGERTON JEROME A
IPC分类号： A61B3/11 , A61B5/103
CPC分类号： A61B3/112 , A61B3/0008 , A61B3/107 , A61B5/0059 , A61B5/0071 , A61B5/411 , A61B5/445 , G02B27/024
摘要： Certain embodiments include medical devices for capturing images of a localized portion of a body, such as the eye or skin tissue. An exemplary system utilizes a hand-held portable viewer. Various embodiments of the viewer have telecentric optics with a focal length of between about six inches and about twelve inches. The viewer also includes an image sensor adapted to capture an image of the object being studied, and may include one or more illumination sources selectively operate e to illuminate the object. A light meter that measures a light level reflected from the object and a level that measures a rotational position of the viewer relative to a reference level position may be included. One or more filters may be removably fastenable to the viewer to cover the illumination source or sources and/or the aperture.
摘要翻译：某些实施例包括用于捕获诸如眼睛或皮肤组织的身体的局部部分的图像的医疗装置。示例性系统利用手持便携式观看者。观众的各种实施例具有焦距在约六英寸至约十二英寸之间的远心光学元件。观看者还包括适于拍摄被研究对象的图像的图像传感器，并且可以包括一个或多个照明源选择性地操作以照亮对象。可以包括测量从物体反射的光级的光度计和测量观察者相对于参考水平位置的旋转位置的水平。一个或多个过滤器可以可拆卸地紧固到观察者以覆盖照明源或/或孔。

3. 发明申请

WO2010111520A1 CONTACT LENS WITH MERIDIONAL SAGITTAL VARIATION AND METHODS FOR MAKING AND USING THE SAME 审中-公开
标题翻译：具有麦芽糖变性的接触镜片及其制造和使用方法
公开(公告)号：WO2010111520A1
公开(公告)日：2010-09-30
申请号：PCT/US2010/028708
申请日：2010-03-25
申请人： CRT TECHNOLOGY, INC. , LEGERTON, Jerome A. , MEYERS, William E.
发明人： LEGERTON, Jerome A. , MEYERS, William E.
IPC分类号： G02C7/04
CPC分类号： G02C7/041 , G02C7/047 , G02C7/048
摘要： The present invention is directed toward the design of lenses to incorporate elevation features in at least one annular zone on the posterior surface of the lens that engage the elevation differences of the eye while allowing the central zone of the lens to have conventional spherical, aspheric, multifocal or toric geometry. In various embodiments, lenses according to the present invention are rotationally stable, free of flexure and well centered over the pupil.
摘要翻译：本发明涉及透镜的设计，以将透镜的后表面上的至少一个环形区域中的高度特征结合，从而使透镜的中心区域具有常规的球面，非球面，多焦点或复曲面几何。在各种实施例中，根据本发明的透镜是旋转稳定的，没有挠曲并且在瞳孔上以中心为中心。

4. 发明申请

WO2015155748A1 OPHTHALMIC EYEWEAR FOR REGULATING OCULAR EXPOSURE TO HIGH ENERGY ELECTROMAGNETIC RADIATION 审中-公开
标题翻译：用于调节高能量电磁辐射的眼睛接触的眼科眼睛
公开(公告)号：WO2015155748A1
公开(公告)日：2015-10-15
申请号：PCT/IB2015/052633
申请日：2015-04-10
申请人： LEGERTON, Jerome A.
发明人： LEGERTON, Jerome A.
IPC分类号： G02C7/10
CPC分类号： G02C7/104 , G02C7/02 , G02C7/04 , G02C7/10 , G02C7/101 , G02C7/102 , G02C2202/16
摘要： Ophthalmic eyewear is provided, comprising a frame and a spectacle lens having a filter and being disposed within the frame or a contact lens having a filter disposed thereon or therein. The filter comprises a spectral characteristic that modulates the transmission of ambient light to protect the eyes of the wearer from damage and loss of vision caused by high energy wavelengths of light.
摘要翻译：提供了眼科眼镜，其包括框架和具有过滤器并且设置在框架内的眼镜镜片或具有设置在其上或其中的过滤器的隐形眼镜。该滤波器包括调制环境光的透射以保护佩戴者的眼睛免受由高能量波长的光引起的损害和视力丧失的光谱特征。

5. 发明申请

WO2010123824A1 SCLERAL CONTACT LENS AND METHODS FOR MAKING AND USING THE SAME 审中-公开
标题翻译： SCLERAL接触镜片及其制造和使用方法
公开(公告)号：WO2010123824A1
公开(公告)日：2010-10-28
申请号：PCT/US2010/031619
申请日：2010-04-19
申请人： CRT TECHNOLOGY, INC. , LEGERTON, Jerome A. , MEYERS, William E.
发明人： LEGERTON, Jerome A. , MEYERS, William E.
IPC分类号： G02C7/04
CPC分类号： G02C7/04 , G02C7/047
摘要： In accordance with exemplary embodiments, the present invention provides scleral lenses comprising a central zone and at least one peripheral zone defined by an angle. In an exemplary embodiment, a peripheral zone is curved in either a concave or convex direction or is uncurved. In an exemplary embodiment, the angle for a plurality of semi-meridians or transverse sections can be varied to create a transverse undulation of a peripheral zone. In accordance with exemplary embodiments, the present invention provides scleral lenses that do not demonstrate excessive pressure on the sclera and that allow for post lens tear exchange. The present invention also provides kits of scleral lenses.
摘要翻译：根据示例性实施例，本发明提供了包括中心区域和由角度限定的至少一个外围区域的巩膜镜片。在示例性实施例中，周边区域在凹形或凸形方向上弯曲或不弯曲。在示例性实施例中，可以改变多个半经线或横向部分的角度以产生周边区域的横向起伏。根据示例性实施例，本发明提供巩膜镜片，其不会对巩膜表现出过大的压力并且允许镜片后撕裂交换。本发明还提供巩膜镜片套件。

6. 发明申请

WO1998025180A1 METHODS FOR FABRICATING ANNULAR MASK LENS HAVING DIFFRACTION-REDUCING EDGES 审中-公开
标题翻译：用于制造具有衍射减少边缘的环形遮蔽镜的方法
公开(公告)号：WO1998025180A1
公开(公告)日：1998-06-11
申请号：PCT/US1997020354
申请日：1997-11-20
申请人： PBH, INC. , EVANS, John, M. , VAN HOUTEN, Norman , LEE, Chun-Shen , DOSHI, Praful, C. , LEGERTON, Jerome, A.
发明人： PBH, INC.
IPC分类号： G03F07/00
CPC分类号： G02C7/028 , A61F2/147 , A61F2/1613 , G02C7/16 , G02C2202/04 , G03F7/001
摘要： Methods for fabricating annular mask lens for vision correction having diffraction-reduction edges are provided. The lens body having an annular mask that forms a "soft edge" by gradually decreasing the transmissivity radially from the center aperture to the annular mask area. The methods introduce varying levels of a coloring agent (e.g., dye) into certain portions of the lens.
摘要翻译：提供了用于制造具有衍射衰减边缘的用于视力矫正的环形掩模透镜的方法。透镜体具有环形掩模，通过从中心孔径向减小到环形掩模区域的透射率而形成“软边缘”。该方法将不同程度的着色剂（例如染料）引入透镜的某些部分。

7. 发明申请

WO2013158418A1 EYE-WEAR BORNE ELECTROMAGNETIC RADIATION REFRACTIVE THERAPY 审中-公开
公开(公告)号：WO2013158418A1
公开(公告)日：2013-10-24
申请号：PCT/US2013/035851
申请日：2013-04-09
申请人： LEGERTON, Jerome, A.
发明人： LEGERTON, Jerome, A.
IPC分类号： G02C7/04
CPC分类号： A61N2/004 , A61B3/0008 , G02C7/04 , G02C7/049 , G02C7/086 , G02C11/00 , G02C11/04 , G02C2202/24
摘要： An eye- wear borne electromagnetic radiation refractive therapy system can comprise an electromagnetic radiation source comprising a ring of LEDs that directs one of its on axis or off axis electromagnetic radiation to a desired peripheral retina area of a wearer's eye; a power source for powering the LEDs, an antenna for receiving signals and a processor for controlling the LEDs; wherein the electromagnetic radiation source includes spectral characteristics similar to outdoor light.
摘要翻译：戴眼罩的电磁辐射折射治疗系统可以包括电磁辐射源，其包括将其轴线或离轴电磁辐射中的一个引导到佩戴者眼睛的期望的外围视网膜区域的LED环; 用于为LED供电的电源，用于接收信号的天线和用于控制LED的处理器; 其中电磁辐射源包括类似于室外光的光谱特性。

8. 发明申请

WO2012047399A1 KIT OF HIGHER ORDER ABERRATION CONTACT LENSES AND METHODS OF USE 审中-公开
标题翻译：更高订单接触镜头套件及其使用方法
公开(公告)号：WO2012047399A1
公开(公告)日：2012-04-12
申请号：PCT/US2011/049195
申请日：2011-08-25
申请人： LIGUORI MANAGEMENT , LEGERTON, Jerome, A.
发明人： LEGERTON, Jerome, A.
IPC分类号： G02C7/04
CPC分类号： G02C7/04 , G02C2202/22
摘要： The present invention provides a kit of contact lenses, comprising two or more contact lenses having a known higher order aberration for each given lens power. By way of example, the higher order aberration may comprise a spherical aberration, a coma aberration, or a trefoil aberration. A practitioner selects a lens from the kit and applies the lens to a patient's eye and measures a residual higher order abemition of the lens-eye system. In cases where the residual higher order aberration exceeds a predetermined magnitude, the practitioner selects a second lens from the kit, applies the second lens to the patient's eye and measures the residual higher order aberration of the lens-eye system.
摘要翻译：本发明提供了一种隐形眼镜套件，其包括两个或更多个具有针对每个给定透镜功率的已知高阶像差的隐形眼镜。作为示例，较高阶像差可以包括球面像差，彗形像差或三倍像差。从业者从套件中选择一个镜片，并将镜片应用于病人的眼睛，并测量镜片眼系统残留的更高次序。在剩余高阶像差超过预定幅度的情况下，从业者从套件中选择第二透镜，将第二透镜施加到患者眼睛并测量眼镜系统的残余高阶像差。

9. 发明申请

WO2012012757A1 SYSTEM AND METHOD FOR TESTING RETINAL FUNCTION 审中-公开
标题翻译：用于测试离体功能的系统和方法
公开(公告)号：WO2012012757A1
公开(公告)日：2012-01-26
申请号：PCT/US2011/045065
申请日：2011-07-22
申请人： PREVENTIVE OPHTHALMICS , LEGERTON, Jerome, A. , FEHER, Akos , FEHER, Janos
发明人： LEGERTON, Jerome, A. , FEHER, Akos , FEHER, Janos
IPC分类号： A61B3/113
CPC分类号： A61B3/10 , A61B3/0033 , A61B3/113 , G06F19/00
摘要： A method of measuring retinal or visual pathway function comprises stimulating optokinetic nystagmus by presenting a visual stimulus to a patient; modifying a first parameter of the visual stimulus; modifying a second parameter of the visual stimulus; and using the modified visual stimulus to determine a threshold stimulus for optokinetic nystagmus; wherein the first and second parameters are selected from a group of parameters comprising a pattern for the visual stimulus, a width of the visual stimulus, a distance between the visual stimulus and the patient, a spatial frequency of the visual stimulus, a rate of change or temporal frequency of the test face of the visual stimulus, and a contrast between elements of the visual stimulus.
摘要翻译：测量视网膜或视觉通路功能的方法包括通过向患者呈现视觉刺激来刺激视动眼震; 修改视觉刺激的第一参数; 修改视觉刺激的第二参数; 并使用经修改的视觉刺激来确定视神经震颤的阈值刺激; 其中所述第一和第二参数选自包括视觉刺激的图案，视觉刺激的宽度，视觉刺激和患者之间的距离，视觉刺激的空间频率，变化率的参数组或视觉刺激的测试面的时间频率，以及视觉刺激的元素之间的对比度。

10. 发明申请

WO2011116114A1 LAMINATED COMPOSITE LENS 审中-公开
标题翻译：层合复合镜
公开(公告)号：WO2011116114A1
公开(公告)日：2011-09-22
申请号：PCT/US2011/028697
申请日：2011-03-16
申请人： LIGUORI MANAGEMENT , LEGERTON, Jerome, A.
发明人： LEGERTON, Jerome, A.
IPC分类号： G02C7/04
CPC分类号： G02C7/049 , B29D11/00048 , B29D11/00076 , B29D11/00105 , G02C7/04 , G02C2202/16
摘要： The present invention is directed to a composite lens, comprising an anterior rigid gas permeable layer, and an annulus of soft material bonded to a posterior surface of the anterior rigid gas permeable layer, wherein a central zone of the composite lens is rigid and without a soft layer, wherein a peripheral zone of the composite lens is generally rigid in its anterior aspect and soft in its posterior aspect.
摘要翻译：本发明涉及一种复合透镜，其包括前刚性气体可渗透层和粘合到前部刚性气体可渗透层的后表面的软质材料环，其中复合透镜的中心区域是刚性的且没有软层，其中复合透镜的周边区域在其前部方面通常是刚性的，并且在后部方面是软的。

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