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1. 发明申请

WO2010018882A1 APPARATUS FOR VISUALIZING AND ANALYZING GENE EXPRESSION PATTERNS USING GENE ONTOLOGY TREE AND METHOD THEREOF 审中-公开
标题翻译：用于使用基因本体树观察和分析基因表达模式的装置及其方法
公开(公告)号：WO2010018882A1
公开(公告)日：2010-02-18
申请号：PCT/KR2008/004735
申请日：2008-08-14
申请人： KOREA BASIC SCIENCE INSTITUTE , KWON, Kyung-Hoon , PARK, Gun Wook , LEE, Jeong Hwa , YOO, Jong Shin
发明人： KWON, Kyung-Hoon , PARK, Gun Wook , LEE, Jeong Hwa , YOO, Jong Shin
IPC分类号： G06F17/30 , C12Q1/68
CPC分类号： G06F19/28 , G06F19/20 , G06F19/26
摘要： The present invention relates to an apparatus for visualizing or analyzing gene expression patterns of a biological sample using gene ontology tree and a method of the same, more precisely, an apparatus for visualizing or analyzing gene expression patterns which are regarded as biologically important using gene ontology tree by calculating complexity and a method of the same. This apparatus of the present invention is useful for comparing gene expression patterns in different biological samples using data produced by the said apparatus and the method of the present invention. According to the present invention, gene expression patterns in relation to molecular functions, biological processes or cellular components can be analyzed by investigating protein or RNA expression in biological samples. So, the apparatus and the method of the present invention can be effectively used for analysis of biologically important aspects such as functional changes, evolutionary stages or developmental stages of each biological sample.
摘要翻译：本发明涉及使用基因本体树来观察或分析生物样品的基因表达模式的装置及其方法，更确切地说，涉及用于使用基因本体论被视为生物学重要性的基因表达模式进行可视化或分析的装置树的计算复杂度和方法相同。本发明的该装置可用于使用由所述装置产生的数据和本发明的方法来比较不同生物样品中的基因表达模式。根据本发明，可以通过研究生物样品中的蛋白质或RNA表达来分析与分子功能，生物过程或细胞成分有关的基因表达模式。因此，本发明的装置和方法可以有效地用于生物学重要方面的分析，例如每个生物样品的功能变化，进化阶段或发育阶段。

2. 发明申请

WO2003060522A1 METHOD FOR THE DIAGNOSIS OF CANCERS BY MEASURING THE CHANGES OF GLYCOSYLATION OF PROTEINS RELATED TO TUMORIGENESIS AND METASTASIS AND KIT FOR DIAGNOSIS OF CANCERS USING THE SAME 审中-公开
标题翻译：通过测量与肿瘤和细胞病变相关的蛋白质糖蛋白变化和用于诊断癌症的试剂盒来诊断癌症的方法
公开(公告)号：WO2003060522A1
公开(公告)日：2003-07-24
申请号：PCT/KR2002/002469
申请日：2002-12-28
申请人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , KO, Jeong Heon , HWANG, Soo Young , SOHN, Hosung , OH, Sejeong , LEE, Jeong Hwa , LEE, Sang Chul , YOO, Jong-Shin , LEE, Dae-Sil
发明人： KO, Jeong Heon , HWANG, Soo Young , SOHN, Hosung , OH, Sejeong , LEE, Jeong Hwa , LEE, Sang Chul , YOO, Jong-Shin , LEE, Dae-Sil
IPC分类号： G01N33/574
CPC分类号： G01N33/57469
摘要： The present invention relates to a method for diagnosing cancers by measuring proteins associated with tumorigenesis and metastasis, and a diagnostic kit using the same, particularly relates to the method for diagnosing cancers by measuring the changes of glycosylation of proteins and the kit for diagnosis of cancers using the said method. The method and kit of the present invention can effectively be used for the sensitive diagnosis of cancers comprising colon cancer, stomach cancer, lung cancer and liver cancer.
摘要翻译：本发明涉及通过测量与肿瘤发生和转移相关的蛋白质来诊断癌症的方法，以及使用该方法的诊断试剂盒，特别涉及通过测量蛋白质糖基化的变化和用于诊断癌症的试剂盒来诊断癌症的方法使用所述方法。本发明的方法和试剂盒可以有效地用于包括结肠癌，胃癌，肺癌和肝癌的癌症的敏感诊断。

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