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1. 发明申请

WO2007068489A3 A MOLDABLE BIOMATERIAL FOR BONE REGENERATION 审中-公开
标题翻译：用于骨再生的可模制生物材料
公开(公告)号：WO2007068489A3
公开(公告)日：2007-08-02
申请号：PCT/EP2006012082
申请日：2006-12-14
申请人： SCIL TECHNOLOGY GMBH , SIEDLER MICHAEL , HELLERBRAND KLAUS , SCHUETZ ANDREAS , KRUEGER SABRINA
发明人： SIEDLER MICHAEL , HELLERBRAND KLAUS , SCHUETZ ANDREAS , KRUEGER SABRINA
IPC分类号： A61L27/12 , A61L27/56
CPC分类号： A61L27/56 , A61L27/58
摘要： The present invention is directed to a moldable biomaterial comprising a particulate solid porous material and a biodegradable paste material. The paste material and the particulate solid porous material form a matrix usable for the replacement or augmentation of bone. In various embodiments the matrix has a high structural integrity, which does not immediately or shortly after implantation collapse into an amorphous non-porous mass, maintains its porosity after implantation, shows biphasic degradation after implantation and/or has a good resistance against being washed out when it is applied to a wet opened implant site. Active agents can be incorporated in the moldable biomaterial of the present invention, such as bone growth factors. Kits, implants, method of manufacturing as well as medicinal uses are also provided.
摘要翻译：本发明涉及包含颗粒状固体多孔材料和可生物降解的糊状材料的可模制生物材料。糊剂材料和颗粒状固体多孔材料形成可用于替换或增加骨骼的基质。在各种实施方案中，基质具有高结构完整性，其在植入后不立即或不短时间内塌陷成无定形非多孔物质，在植入后保持其孔隙度，在植入后显示双相降解和/或具有良好的抗冲刷性当它被应用到湿开放的植入部位时。活性剂可以掺入本发明的可模制生物材料中，例如骨生长因子。还提供了套件，植入物，制造方法以及医药用途。

2. 发明申请

WO2007068489A2 A MOLDABLE BIOMATERIAL FOR BONE REGENERATION 审中-公开
标题翻译：用于骨再生的可塑生物材料
公开(公告)号：WO2007068489A2
公开(公告)日：2007-06-21
申请号：PCT/EP2006/012082
申请日：2006-12-14
申请人： SCIL TECHNOLOGY GMBH , SIEDLER, Michael , HELLERBRAND, Klaus , SCHUETZ, Andreas , KRUEGER, Sabrina
发明人： SIEDLER, Michael , HELLERBRAND, Klaus , SCHUETZ, Andreas , KRUEGER, Sabrina
IPC分类号： A61L27/12 , A61L27/56
CPC分类号： A61L27/56 , A61L27/58
摘要： The present invention is directed to a moldable biomaterial comprising a particulate solid porous material and a biodegradable paste material. The paste material and the particulate solid porous material form a matrix usable for the replacement or augmentation of bone. In various embodiments the matrix has a high structural integrity, which does not immediately or shortly after implantation collapse into an amorphous non-porous mass, maintains its porosity after implantation, shows biphasic degradation after implantation and/or has a good resistance against being washed out when it is applied to a wet opened implant site. Active agents can be incorporated in the moldable biomaterial of the present invention, such as bone growth factors. Kits, implants, method of manufacturing as well as medicinal uses are also provided.
摘要翻译：本发明涉及一种可模制生物材料，其包括颗粒状固体多孔材料和可生物降解的糊料。糊状材料和颗粒状固体多孔材料形成可用于骨的更换或增加的基质。在各种实施方案中，基质具有高的结构完整性，其在植入塌陷成无定形无孔团块之后不立即或不久，在植入后保持其孔隙度，在植入后显示双相降解和/或具有良好的耐洗涤性当它被施加到湿开放的植入部位时。活性剂可以掺入本发明的可模制生物材料中，例如骨生长因子。还提供了套件，植入物，制造方法以及药用。

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