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1. 发明申请

WO2007106608A3 LIGHT BEAM TARGETING AND POSITIONING SYSTEM FOR A PAINT OR COATING REMOVAL BLASTING SYSTEM 审中-公开
标题翻译：一种涂料或涂料去除爆破系统的光束定位和定位系统
公开(公告)号：WO2007106608A3
公开(公告)日：2007-12-21
申请号：PCT/US2007060607
申请日：2007-01-17
申请人： UNIV NORTHERN IOWA RES FOUNDAT , LAMPE CHRISTOPHER A , KLEIN RICHARD J II
发明人： LAMPE CHRISTOPHER A , KLEIN RICHARD J II
IPC分类号： B24C1/00 , B05B15/06 , G01B11/02
CPC分类号： B24C1/086 , B05B15/08
摘要： A blasting system for the removal of coatings or paint from an underlying surface uses an optical device to position the blasting nozzle an appropriate stand¬ off distance from the surface. The blasting media can use a variety of blasting media including abrasives, water, and various specialty blasting media. The preferred optical system is mounted to or integral with the blasting nozzle, and uses a diode laser, a beam splitter and a reflecting mirror to generate a reference beam and a gauge beam. Alternatively, two diode lasers can be used to generate the reference beam and gauge beam respectively. The reference beam propagates in a fixed forward direction, but the direction of the gauge beam is adjustable. The user adjusts the orientation of the gauge beam so that the image of the beam on the surface aligns with the image of the reference beam on the surface when the blasting nozzle is positioned at the appropriate stand-off distance from the surface. Alternatively, the center of the blasting pattern o the surface can be used as a rough estimate for the reference beam, thereby avoiding the need to generate and align two non-parallel beams.
摘要翻译：用于从底层表面去除涂层或油漆的喷砂系统使用光学装置将喷砂喷嘴定位在离表面适当的距离处。爆破介质可以使用各种喷砂介质，包括磨料，水和各种专业喷砂介质。优选的光学系统安装在喷射喷嘴上或与喷射喷嘴集成，并使用二极管激光器，分束器和反射镜来产生参考光束和测量光束。或者，可以使用两个二极管激光器分别产生参考光束和测量光束。参考光束在固定的正向传播，但量规光束的方向是可调的。用户调节标准光束的方向，以便当喷射喷嘴位于离表面适当的距离时，表面上的光束图像与表面上参考光束的图像对齐。或者，表面喷砂图案的中心可用作参考光束的粗略估计，从而避免产生和对准两个不平行光束的需要。

2. 发明申请

WO2007106608A2 LIGHT BEAM TARGETING AND POSITIONING SYSTEM FOR A PAINT OR COATING REMOVAL BLASTING SYSTEM 审中-公开
标题翻译：用于涂料或涂层去除喷砂系统的光束瞄准和定位系统
公开(公告)号：WO2007106608A2
公开(公告)日：2007-09-20
申请号：PCT/US2007/060607
申请日：2007-01-17
申请人： UNIVERSITY OF NORTHERN IOWA RESEARCH FOUNDATION , LAMPE, Christopher, A. , KLEIN, Richard, J., II
发明人： LAMPE, Christopher, A. , KLEIN, Richard, J., II
CPC分类号： B24C1/086 , B05B15/68
摘要： A blasting system for the removal of coatings or paint from an underlying surface uses an optical device to position the blasting nozzle an appropriate stand¬ off distance from the surface. The blasting media can use a variety of blasting media including abrasives, water, and various specialty blasting media. The preferred optical system is mounted to or integral with the blasting nozzle, and uses a diode laser, a beam splitter and a reflecting mirror to generate a reference beam and a gauge beam. Alternatively, two diode lasers can be used to generate the reference beam and gauge beam respectively. The reference beam propagates in a fixed forward direction, but the direction of the gauge beam is adjustable. The user adjusts the orientation of the gauge beam so that the image of the beam on the surface aligns with the image of the reference beam on the surface when the blasting nozzle is positioned at the appropriate stand-off distance from the surface. Alternatively, the center of the blasting pattern o the surface can be used as a rough estimate for the reference beam, thereby avoiding the need to generate and align two non-parallel beams.
摘要翻译：用于从下面的表面去除涂层或涂料的喷砂系统使用光学装置来将喷射喷嘴定位在离表面适当的距离处。爆破介质可以使用各种爆破介质，包括磨料，水和各种特种爆破介质。优选的光学系统安装在爆破喷嘴上或与爆破喷嘴一体，并且使用二极管激光器，分束器和反射镜来产生参考光束和光束。或者，可以使用两个二极管激光器来分别产生参考光束和光束。参考光束以固定的正向传播，但是光束的方向是可调节的。使用者调整量规束的方向，使得当喷砂喷嘴位于离表面适当的间隔距离时，表面上的光束的图像与表面上的参考光束的图像对准。或者，表面上的喷砂图案的中心可以用作参考光束的粗略估计，从而避免生成和对准两个非平行光束。

3. 发明申请

WO2007092043A2 BIOACTIVE MATERIAL DELIVERY SYSTEMS COMPRISING SOL-GEL COMPOSITIONS 审中-公开
标题翻译：包含SOL凝胶组合物的生物材料输送系统
公开(公告)号：WO2007092043A2
公开(公告)日：2007-08-16
申请号：PCT/US2006/031271
申请日：2006-08-08
申请人： MEDLOGICS DEVICE CORPORATION , STANFORD UNIVERSITY , PANTELIDIS, Dimitrios , BRAVMAN, John, C. , ROTHBARD, Jonathan , KLEIN, Richard, L.
发明人： PANTELIDIS, Dimitrios , BRAVMAN, John, C. , ROTHBARD, Jonathan , KLEIN, Richard, L.
IPC分类号： A61L31/08 , A61L31/16
CPC分类号： A61L27/306 , A61L27/54 , A61L31/088 , A61L31/16 , A61L2300/608
摘要： Implantable medical devices employing a sol-gel composition coatings that functions as a bioactive material reservoir, and the use of sol-gel composition coatings for improved adhesion of organic and inorganic substrates are disclosed.
摘要翻译：公开了使用用作生物活性材料储存器的溶胶 - 凝胶组合物涂层的植入式医疗装置，以及使用溶胶 - 凝胶组合物涂层来改善有机和无机基材的粘合性。

4. 发明申请

WO2007056556A2 PYRIDINIUM AND THIAZOLIUM CONJUGATES INCLUDING POLYETHYLENE GLYCOLS AND METHODS OF USING THE SAME 审中-公开
标题翻译：含有聚乙二醇的吡啶和二硫酸铵及其使用方法
公开(公告)号：WO2007056556A2
公开(公告)日：2007-05-18
申请号：PCT/US2006/043748
申请日：2006-11-08
申请人： MYCOSOL, INC. , SELPH, Jeffrey, L. , KLEIN, Richard, B. , PARTRIDGE, John, J.
发明人： SELPH, Jeffrey, L. , KLEIN, Richard, B. , PARTRIDGE, John, J.
IPC分类号： A61K31/4545
CPC分类号： C07D213/38 , A01N43/40 , A01N43/78
摘要： Pegylated pyridinium and thiazolium compounds and methods of their use in medicine, research, industry, agriculture and recreational activities are disclosed. The present invention also provides methods of controlling microbial growth and infection. Additionally, the present invention provides methods of controlling microbial infestations relating to industrial and agricultural uses. The present invention can also be used to control insects.
摘要翻译：公开了聚乙二醇化吡啶鎓和噻唑鎓化合物及其在医药，研究，工业，农业和娱乐活动中的用途。本发明还提供了控制微生物生长和感染的方法。此外，本发明提供了控制与工业和农业用途有关的微生物侵染的方法。本发明也可用于控制昆虫。

5. 发明申请

WO2003011114A3 METHODS FOR TREATING PROSTATITIS 审中-公开
公开(公告)号：WO2003011114A3
公开(公告)日：2003-02-13
申请号：PCT/US2002/024221
申请日：2002-07-24
申请人： WIT IP CORPORATION , CIOANTA, Iulian , KLEIN, Richard, Barry , DIMITRIKOV, Jordan
发明人： CIOANTA, Iulian , KLEIN, Richard, Barry , DIMITRIKOV, Jordan
IPC分类号： A61F2/00
摘要： Methods, systems, and computer program products for providing thermal therapies or internal thermal massage therapy for treating prostatitis by expanding and contracting a treatment balloon with inflation media and currently applying heat to a portion of the prostatic urethra.

6. 发明申请

WO2003011114A2 METHODS FOR TREATING PROSTATITIS 审中-公开
标题翻译：治疗前景的方法
公开(公告)号：WO2003011114A2
公开(公告)日：2003-02-13
申请号：PCT/US2002/024221
申请日：2002-07-24
申请人： ARGOMED, LTD. , CIOANTA, Iulian , KLEIN, Richard, Barry , DIMITRIKOV, Jordan
发明人： CIOANTA, Iulian , KLEIN, Richard, Barry , DIMITRIKOV, Jordan
IPC分类号： A61B
CPC分类号： A61F7/12 , A61B2017/00274 , A61B2018/00547 , A61H9/0078 , A61H21/00 , A61H2201/0207 , A61H2201/0214 , A61H2201/0242 , A61H2201/0257 , A61H2201/0292 , A61H2201/10 , A61H2201/5007
摘要： Methods, systems, and computer program products for providing thermal therapies or internal thermal massage therapy for treating prostatitis by expanding and contracting a treatment balloon with inflation media and currently applying heat to a portion of the prostatic urethra.
摘要翻译：方法，系统和计算机程序产品，用于通过用膨胀介质扩张和收缩治疗气球并且目前对前列腺尿道的一部分施加热量来提供热治疗或内部热按摩治疗来治疗前列腺炎。

7. 发明申请

WO2002058578A1 TREATMENT CATHETERS WITH THERMALLY INSULATED REGIONS 审中-公开
标题翻译：治疗导管与热绝缘区域
公开(公告)号：WO2002058578A1
公开(公告)日：2002-08-01
申请号：PCT/US2001/047793
申请日：2001-11-13
申请人： ARGOMED, LTD. , CIOANTA, Iulian , KLEIN, Richard, Barry , LAZAROVITZ, Jacob
发明人： CIOANTA, Iulian , KLEIN, Richard, Barry , LAZAROVITZ, Jacob
IPC分类号： A61B18/08
CPC分类号： A61B18/04 , A61B2017/00274 , A61B2017/22069 , A61B2018/00547 , A61B2018/046 , A61F7/123 , A61M31/00 , A61M2210/166
摘要： Flexible treatment catheters are configured to be inserted into a body lumen or cavity to deliver heated fluid through at least one fluid lumen therein to thermally treat or ablate a targeted site in a biological subject. The flexible treatment catheters can include improved thermally insulated regions comprising a mixture formed of liquid elastomeric (such as a polyurethane) mixture (which transitions to a solid state) and miniaturized hollow plastic bodies positioned between the outer wall of the treatment catheter and the fluid lumen. The thermally insulated region is configured such that, measured ex vivo, the treatment catheter can present a maximum temperature of below about 45°C on the external surface of the outer wall of the treatment catheter when the treatment catheter circulates fluid having an inlet temperature of above or between about 60°-62°C. Alternatively or additionally, the treatment catheter can include an elongated insert positioned in a catheter fluid lumen to inhibit the closure of the lumen after exposure to fluids in the treatment catheter at temperatures sufficient to thermal ablate targeted tissue over a thermal ablation treatment period. The treatment catheter can include a urinary drainage lumen with an elongated insert frictionally engaged therewith, the drainage lumen and insert are configured to provide a fluid volume throughput through the drainage lumen of greater than about 20-25 ml/min during and after (for about 12-72 hours after) a thermal ablation session.
摘要翻译：柔性治疗导管被构造成插入体腔或空腔中以将加热的流体通过其中的至少一个流体腔传递到热处理或消融生物学对象中的靶位点。柔性治疗导管可以包括改进的热绝缘区域，其包括由液体弹性体（例如聚氨酯）混合物（其转变为固体状态）和位于治疗导管的外壁和流体内腔之间的小型化中空塑料体形成的混合物。隔热区域被构造成使得，离体测量时，当处理导管循环具有入口温度的流体的流体时，治疗导管可以在治疗导管的外壁的外表面上呈现低于约45℃的最高温度或者或另外，治疗导管可以包括定位在导管流体腔中的细长插入物，以在暴露于治疗导管中的流体以在足以热消融的温度下抑制内腔闭合在热消融治疗期间的靶组织。治疗导管可以包括具有与其摩擦接合的细长插入件的排尿腔，排液腔和插入物被配置成在其期间和之后提供大于约20-25ml / min的流体体积通过排液腔 12-72小时后）热消融术。

8. 发明申请

WO2007086900A3 STILBAZIUM RESEARCH ASSAYS 审中-公开
标题翻译：斯德哥尔摩研究测定
公开(公告)号：WO2007086900A3
公开(公告)日：2009-04-16
申请号：PCT/US2006012942
申请日：2006-04-07
申请人： MYCOSOL INC , SELPH JEFFREY L , SHARMA JAYENDRA , PARTRIDGE JOHN J , KLEIN RICHARD B
发明人： SELPH JEFFREY L , SHARMA JAYENDRA , PARTRIDGE JOHN J , KLEIN RICHARD B
IPC分类号： A01N43/42 , A61K31/44 , C07D213/00 , C07D213/02
CPC分类号： C07D213/38 , C07D401/14
摘要： Methods for determining the presence, absence, health or interaction between cells analytes, nucleic acids or microorganisms in a sample are provided. Compounds that fluoresce and kits containing the same are also provided.
摘要翻译：提供了确定样品中细胞分析物，核酸或微生物之间存在，不存在，健康或相互作用的方法。还提供了发荧光的化合物和含有该化合物的试剂盒。

9. 发明申请

WO2007056340A2 DISINFECTANT AND ANTISEPTIC PYRIDINIUM AND THIAZOLIUM COMPOUNDS AND METHODS OF USING THE SAME 审中-公开
标题翻译：消毒剂和抗菌剂吡啶鎓和噻唑化合物及其使用方法
公开(公告)号：WO2007056340A2
公开(公告)日：2007-05-18
申请号：PCT/US2006/043285
申请日：2006-11-08
申请人： MYCOSOL, INC. , SELPH, Jeffrey L. , KLEIN, Richard B. , PARTRIDGE, John J.
发明人： SELPH, Jeffrey L. , KLEIN, Richard B. , PARTRIDGE, John J.
IPC分类号： A61K31/4545
CPC分类号： A61K31/4545
摘要： Long lasting pyridinium and thiazolium compounds and methods of their use in medicine, industry, agriculture and recreational activities are disclosed. The present invention also relates to methods of controlling microbial growth and infection.
摘要翻译：公开了长效的吡啶鎓和噻唑鎓化合物及其在医药，工业，农业和娱乐活动中的用途。本发明还涉及控制微生物生长和感染的方法。

10. 发明申请

WO2007024401A1 HYBRID LUMEN-SUPPORTING STENTS HAVING SELF-EXPANDING END SEGMENTS 审中-公开
标题翻译：具有自扩展末端部分的混合支持支架
公开(公告)号：WO2007024401A1
公开(公告)日：2007-03-01
申请号：PCT/US2006/029094
申请日：2006-07-26
申请人： MEDLOGICS DEVICE CORPORATION , LEE, Michael, J. , KLEIN, Richard, L.
发明人： LEE, Michael, J. , KLEIN, Richard, L.
IPC分类号： A61F2/84 , A61F2/90
CPC分类号： A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2002/91583 , A61F2002/9583 , A61F2220/005 , A61F2220/0058 , A61F2230/0054 , A61F2250/0048 , A61L31/022 , A61L31/14
摘要： A stent and stent deployment system and related methods are disclosed wherein the stent has at least one end segment (32) comprised of a self -expanding material attached to a body portion (30) comprised of a biocompatible material. The stent deployment system comprises a balloon catheter (12) having a stent (16) disposed over the balloon (14) . In one embodiment a stent's end segments (32,34) extend beyond the proximal and distal ends of the balloon such that they are able to stent a portion of a vessel not expanded or damaged by balloon expansion. This stenting beyond area expanded or damaged by balloon expansion provides for a less abrupt transition between stented and unstented portions of a vessel.
摘要翻译：公开了一种支架和支架展开系统及相关方法，其中所述支架具有至少一个端部段（32），所述端部段（32）包括附着于由生物相容性材料构成的主体部分（30）的自展开材料。支架展开系统包括具有设置在气囊（14）上方的支架（16）的球囊导管（12）。在一个实施例中，支架的端部段（32,34）延伸超过气囊的近端和远端，使得它们能够支架未膨胀或被球囊扩张损坏的血管的一部分。通过球囊膨胀扩张或损伤的超出区域的支架提供了在血管的支架和未部分部分之间的较不突然的过渡。

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