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    • 1. 发明申请
    • DRUG DISPENSER
    • 药物分配器
    • WO2008023019A3
    • 2008-05-29
    • PCT/EP2007058679
    • 2007-08-21
    • GLAXO GROUP LTDANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • ANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • B05B11/00A61M15/00
    • A61M15/009A61M15/0025A61M15/0075A61M15/0081A61M15/0096A61M2205/276A61M2205/8281B65D83/16
    • There is provided a drug dispenser device (1) comprising a housing (10a, 10b, 12), extending from the housing, an outlet (16) for insertion into a body-cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the drug discharge device, a container collar; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger (20a, 20b) operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction, linking the container collar with the transfer element, a biasing mechanism to store biasing energy on moving the transfer element along the longitudinal axis in the first direction; and provided to the container collar, a pre-load mechanism to prevent transfer of the biasing energy to the container collar to move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism until a pre-determined threshold force is overcome.
    • 提供了一种药物分配器装置(1),其包括从壳体延伸的壳体(10a,10b,12),用于插入患者体腔的出口(16); 提供给壳体并相对于其可移动的药物排出装置,具有纵向轴线并包括用于储存待分配的药物制剂的容器,排出机构和来自容器的排出通道,用于将药物制剂排出到出口 ; 连接到药物排出装置,容器衣领; 连接到所述容器套环并且沿着所述药物排出装置的纵向轴线可相对于其移动;转移元件,所述转移元件包括致动部分; 提供给壳体的至少一个手指(20a,20b)可操作构件可移动以对传递元件的致动部分施加力,以沿第一方向沿着纵向轴线移动传递元件,将容器环与传送件 元件,偏置机构,用于在第一方向沿着纵向轴线移动传递元件时存储偏置能量; 并且提供给所述容器套环,所述预加载机构用于防止所述偏置能量转移到所述容器套环,以沿所述纵向轴线沿所述第一方向移动所述药物排出装置,以启动所述排放机构,直到预定的阈值力为 克服。
    • 3. 发明申请
    • DRUG DISPENSER
    • 药物分配器
    • WO2008110584A3
    • 2008-11-27
    • PCT/EP2008052967
    • 2008-03-12
    • GLAXO GROUP LTDANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASELLIMAN DAVID VINCENTKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • ANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASELLIMAN DAVID VINCENTKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • A61M15/00
    • A61M15/009A61M15/0026A61M15/0075A61M15/0091A61M15/0096A61M2205/6081G06M1/04G06M1/083
    • One aspect provides a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the container, a container collar connected to the discharge device; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction; linking the container collar with the transfer element, a biasing mechanism to store biasing energy on moving the transfer element along the longitudinal axis in the first direction; an actuation counter; and provided to the container collar, a pre-load mechanism to prevent transfer of the biasing energy to the container collar to both move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism and also to actuate the actuation counter until a pre-determined threshold force is overcome.
    • 一方面提供了一种药物分配器装置,其包括壳体; 从壳体延伸,用于插入患者体腔中的出口; 所述药物排出装置具有纵向轴线并且包括用于储存待分配的药物制剂的容器,排出机构和从容器排出药物制剂到排出口的排出通道 ; 连接到所述容器,连接到所述排放装置的容器套环; 连接到所述容器套环并且能够沿着所述药物排放装置的纵向轴线相对于所述容器套环移动;传递元件,所述传递元件包括致动部分; 提供给所述壳体的至少一个手指可操作构件,所述至少一个手指可操作构件可移动以向所述传递元件的所述致动部分施加力以沿着所述纵向轴线在第一方向上移动所述传递元件; 将所述容器套环与所述传递元件联接;偏置机构,用于在所述传递元件沿着所述纵向轴线在所述第一方向上移动时存储偏置能量; 一个致动计数器; 并向容器套环提供预加载机构以防止偏置能量传递到容器套环以使药物排放装置沿第一方向沿纵向轴线移动以致动排放机构并且还致动致动计数器 直到克服预定的阈值力。
    • 4. 发明申请
    • DRUG DISPENSER
    • 药物分配器
    • WO2008110584A2
    • 2008-09-18
    • PCT/EP2008/052967
    • 2008-03-12
    • GLAXO GROUP LIMITEDANDERSON, Gregor John McLennanCROSBY, Gary ThomasELLIMAN, David VincentKELLY, Andrew MichaelTEUCHER, Mark DigbyWEST, James Anthony
    • ANDERSON, Gregor John McLennanCROSBY, Gary ThomasELLIMAN, David VincentKELLY, Andrew MichaelTEUCHER, Mark DigbyWEST, James Anthony
    • A61M15/00
    • A61M15/009A61M15/0026A61M15/0075A61M15/0091A61M15/0096A61M2205/6081G06M1/04G06M1/083
    • One aspect provides a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the container, a container collar connected to the discharge device; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction; linking the container collar with the transfer element, a biasing mechanism to store biasing energy on moving the transfer element along the longitudinal axis in the first direction; an actuation counter; and provided to the container collar, a pre-load mechanism to prevent transfer of the biasing energy to the container collar to both move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism and also to actuate the actuation counter until a pre-determined threshold force is overcome.
    • 一方面提供了一种药物分配器装置,其包括壳体; 从所述壳体延伸出用于插入患者体腔的出口; 提供给壳体并相对于其可移动的药物排出装置,具有纵向轴线的药物排出装置,并且包括用于储存待分配的药物制剂的容器,排出机构和来自容器的排出通道,用于将药物制剂排出到出口 ; 连接到容器,连接到排放装置的容器套环; 连接到所述容器套环并且沿着所述药物排出装置的纵向轴线可相对于其移动,所述传递元件包括致动部分; 至少一个手指可操作构件,其可移动以向所述传递元件的所述致动部分施加力以沿所述纵向轴线沿第一方向移动所述传递元件; 将所述容器套环与所述传递元件连接;偏置机构,用于在沿所述第一方向的所述纵向轴线移动所述传递元件时存储偏置能量; 启动计数器 并且提供给容器套环,预加载机构,用于防止偏置能量传递到容器套环,以沿药物排出装置沿着第一方向的纵向轴线移动以致动排出机构并且还致动致动计数器 直到克服了预定阈值力。
    • 5. 发明申请
    • DRUG DISPENSER
    • 药物分配器
    • WO2008023019A2
    • 2008-02-28
    • PCT/EP2007/058679
    • 2007-08-21
    • GLAXO GROUP LIMITEDANDERSON, Gregor, John, McLennanCROSBY, Gary, ThomasKELLY, Andrew, MichaelTEUCHER, Mark, DigbyWEST, James, Anthony
    • ANDERSON, Gregor, John, McLennanCROSBY, Gary, ThomasKELLY, Andrew, MichaelTEUCHER, Mark, DigbyWEST, James, Anthony
    • B05B11/00A61M15/00
    • A61M15/009A61M15/0025A61M15/0075A61M15/0081A61M15/0096A61M2205/276A61M2205/8281B65D83/16
    • There is provided a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the drug discharge device, a container collar; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction; linking the container collar with the transfer element, a biasing mechanism to store biasing energy on moving the transfer element along the longitudinal axis in the first direction; and provided to the container collar, a pre-load mechanism to prevent transfer of the biasing energy to the container collar to move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism until a pre-determined threshold force is overcome.
    • 提供了一种药物分配器装置,其包括壳体; 从所述壳体延伸出用于插入患者体腔的出口; 提供给壳体并相对于其可移动的药物排出装置,具有纵向轴线并包括用于储存待分配的药物制剂的容器,排出机构和来自容器的排出通道,用于将药物制剂排出到出口 ; 连接到药物排出装置,容器衣领; 连接到所述容器套环并且沿着所述药物排出装置的纵向轴线可相对于其移动;转移元件,所述转移元件包括致动部分; 提供给所述壳体的至少一个手指可操作构件可移动以向所述传递元件的致动部分施加力,以沿着所述纵向轴线沿第一方向移动所述传递元件; 将所述容器套环与所述传递元件连接;偏置机构,用于在沿所述第一方向沿着所述纵向轴线移动所述传递元件时存储偏置能量; 并且提供给所述容器套环,所述预加载机构用于防止所述偏置能量转移到所述容器套环以沿所述纵向轴线沿所述第一方向移动所述药物排出装置,以致所述排出机构直到预定的阈值力为 克服。
    • 6. 发明申请
    • COUNTER FOR USE WITH A MEDICAMENT DISPENSER
    • 使用药剂分配器的计数器
    • WO2007104964A1
    • 2007-09-20
    • PCT/GB2007/000867
    • 2007-03-13
    • GLAXO GROUP LIMITEDCROSBY, Gary, ThomasELLIMAN, David, VincentKELLY, Andrew, Michael
    • CROSBY, Gary, ThomasELLIMAN, David, VincentKELLY, Andrew, Michael
    • G06M1/26
    • G06M1/166A61M15/0075
    • One aspect provides a dose counter (1) for use with a medicament dispenser which comprises a ratchet (50); a first count wheel (20) arranged to rotate about a first axis of rotation, said first count wheel including one or more ratchet drive receipt elements (24) arranged thereon for receipt of drive from said ratchet to rotate the first count wheel about said first axis of rotation; a second count wheel (30) arranged to rotate about the first axis of rotation, said second count wheel including a set of teeth (34) arranged annularly thereon; and a kick wheel (40) arranged to rotate about a second axis of rotation offset from the first axis of rotation, said kick wheel including a set of kick teeth (44) arranged annularly thereon and in meshed relationship with the teeth of the second count wheel such that rotary motion of the kick wheel results in rotary motion of the second count wheel. The first count wheel further includes at least one fixed index tooth (28a, 28b) arranged for intermittent meshing with the kick teeth of the kick wheel such that rotary motion of the kick wheel results from rotary motion of the first count wheel only when said intermittent meshing occurs.
    • 一个方面提供了一种用于与包括棘轮(50)的药物分配器一起使用的剂量计数器(1) 第一计数轮(20)布置成围绕第一旋转轴线旋转,所述第一计数轮包括布置在其上的一个或多个棘轮传动接收元件(24),用于接收来自所述棘轮的驱动,以使第一计数轮围绕所述第一 旋转轴; 第二计数轮(30)布置成围绕第一旋转轴线旋转,所述第二计数轮包括一组环形地设置的齿(34); 以及踢脚轮(40),其布置成围绕偏离所述第一旋转轴线的第二旋转轴线旋转,所述踢脚轮包括一组环形地布置在其上且与所述第二计数的齿啮合的踢齿(44) 使得脚轮的旋转运动导致第二计数轮的旋转运动。 第一计数轮还包括至少一个固定分度齿(28a,28b),其布置成与踢脚轮的踢齿间歇地啮合,使得踢脚轮的旋转运动由第一计数轮的旋转运动产生,只有当所述间歇 发生啮合。