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1. 发明申请

WO2009008666A3 AUTOLOGOUS DENDRITIC CELL MEDIATED BY PHOTODYNAMIC THERAPY HAVING THE ABILITY TO SUPPRESS THE GROWTH OF TUMOR 审中-公开
标题翻译：具有抑制肿瘤生长的能力的光动力治疗介导的自动细胞细胞
公开(公告)号：WO2009008666A3
公开(公告)日：2009-03-19
申请号：PCT/KR2008004042
申请日：2008-07-09
申请人： CREAGENE INC , KANG MI SUN , LIM DAE-SEOG , JEONG JU-AH , LEE HYUN-SOO , BAE YONG-SOO
发明人： LIM DAE-SEOG , JEONG JU-AH , LEE HYUN-SOO , BAE YONG-SOO
IPC分类号： C12N5/0784
CPC分类号： C12N5/0639 , A61K2035/124 , C12N2501/22 , C12N2501/23 , C12N2501/24 , C12N2501/25 , C12N2502/30
摘要： The present invention relates to mature dendritic cells (DCs) having the enhanced ability to induce anti-tumor immune responses, and to a method for the preparation of the above-mentioned DCs through the procedure of pulsing immature DCs with lysates of cancer cells on which photodynamic therapy (PDT) has been conducted. The dendritic cell of this invention acquires an activity to induce anti-tumor immune responses so that it exerts a remarkable effect to suppress the growth of tumor.
摘要翻译：本发明涉及具有增强的抗肿瘤免疫应答能力的成熟树突状细胞（DCs），以及通过以下步骤制备上述DC的方法：通过以下步骤将不成熟的DC脉冲化：癌细胞的裂解物光动力疗法（PDT）已经进行。本发明的树突细胞获得诱导抗肿瘤免疫应答的活性，从而具有显着的抑制肿瘤生长的作用。

2. 发明申请

WO2008130100A1 SEMI-MATURE DENTRITIC CELL 审中-公开
标题翻译：半成熟细胞
公开(公告)号：WO2008130100A1
公开(公告)日：2008-10-30
申请号：PCT/KR2008/001397
申请日：2008-03-12
申请人： CREAGENE INC. , KANG, Mi-Sun , LIM, Dae-Seog , JEONG, Ju-Ah , LEE, Hyun-Soo , BAE, Yong-Soo
发明人： KANG, Mi-Sun , LIM, Dae-Seog , JEONG, Ju-Ah , LEE, Hyun-Soo , BAE, Yong-Soo
IPC分类号： A61K35/14 , C12N5/00 , A61K48/00
CPC分类号： A61K39/0008 , A61K2035/122 , A61K2039/5154 , C12N5/064 , C12N2501/22 , C12N2501/25
摘要： The present invention relates to a pharmaceutical composition for treating rheumatoid arthritis, which comprises (a) a pharmaceutically effective amount of a semi-mature dendritic cell; and (b) a pharmaceutically acceptable carrier. The semi-mature dendritic cell of this invention has a safe and remarkably improved potential to treat or prevent rheumatoid arthritis through the activity of the suppression of auto-immune responses.
摘要翻译：本发明涉及一种用于治疗类风湿性关节炎的药物组合物，其包含（a）药学有效量的半成熟树突状细胞; 和（b）药学上可接受的载体。本发明的半成熟树突状细胞通过抑制自身免疫应答的活性具有安全和显着改善的治疗或预防类风湿性关节炎的潜力。

3. 发明申请

WO2008060031A1 PORTABLE DEVICE HAVING IMAGE OVERLAY FUNCTION AND METHOD OF OVERLAYING IMAGE IN PORTABLE DEVICE 审中-公开
标题翻译：具有图像覆盖功能的便携式设备和便携式设备中覆盖图像的方法
公开(公告)号：WO2008060031A1
公开(公告)日：2008-05-22
申请号：PCT/KR2007/004377
申请日：2007-09-10
申请人： KTF TECHNOLOGIES, INC. , KANG, Mi-Sun , OH, Jung-Bum
发明人： KANG, Mi-Sun , OH, Jung-Bum
IPC分类号： H04B1/40
CPC分类号： H04N21/44012 , H04N21/23412 , H04N21/41407 , H04N21/4223 , H04N21/4316
摘要： Disclosed are a portable device having an image overlay function and a method of overlaying images in the portable device, which can photograph a plurality of images within areas having no overlapping regions between the areas in real time, and can overlaythe photographed images. A first camera unit photographs a first area, and a second camera unit photographs a second area which does not overlap with the first area. A first codec and a second codec encode a first area image and a second area image, respectively, which have been obtained by photographing the first area and the second area. An image processing unit overlays the encoded first area image and the encoded second area image. Therefore, it is possible to photograph a plurality of subjects existing in at least two areas having no overlapping regions between the two areasin real time, to overlay the photographed images, and to transmit the overlaid image to a portable device of a counterpart for video telephone communication.
摘要翻译：公开了具有图像叠加功能的便携式设备和在便携式设备中重叠图像的方法，其可以在实时地区域之间不具有重叠区域的区域内拍摄多个图像，并且可以重叠拍摄的图像。第一相机单元拍摄第一区域，并且第二相机单元拍摄与第一区域不重叠的第二区域。第一编解码器和第二编解码器分别编码通过拍摄第一区域和第二区域而获得的第一区域图像和第二区域图像。图像处理单元覆盖编码的第一区域图像和编码的第二区域图像。因此，可以实时拍摄存在于两个区域之间没有重叠区域的至少两个区域中的多个对象，以覆盖所拍摄的图像，并将覆盖的图像发送到视频电话的对方的便携式设备通讯。

4. 发明申请

WO2009008666A2 AUTOLOGOUS DENDRITIC CELL MEDIATED BY PHOTODYNAMIC THERAPY HAVING THE ABILITY TO SUPPRESS THE GROWTH OF TUMOR 审中-公开
标题翻译：通过光动力疗法介导的自体树突状细胞具有抑制肿瘤生长的能力
公开(公告)号：WO2009008666A2
公开(公告)日：2009-01-15
申请号：PCT/KR2008/004042
申请日：2008-07-09
申请人： CREAGENE INC. , KANG, Mi-Sun , LIM, Dae-Seog , JEONG, Ju-Ah , LEE, Hyun-Soo , BAE, Yong-Soo
发明人： LIM, Dae-Seog , JEONG, Ju-Ah , LEE, Hyun-Soo , BAE, Yong-Soo
IPC分类号： C12N5/06
CPC分类号： C12N5/0639 , A61K2035/124 , C12N2501/22 , C12N2501/23 , C12N2501/24 , C12N2501/25 , C12N2502/30
摘要： The present invention relates to mature dendritic cells (DCs) having the enhanced ability to induce anti-tumor immune responses, and to a method for the preparation of the above-mentioned DCs through the procedure of pulsing immature DCs with lysates of cancer cells on which photodynamic therapy (PDT) has been conducted. The dendritic cell of this invention acquires an activity to induce anti-tumor immune responses so that it exerts a remarkable effect to suppress the growth of tumor.
摘要翻译：本发明涉及具有增强的诱导抗肿瘤免疫应答能力的成熟树突细胞（DC），并且涉及通过脉冲未成熟的程序制备上述DC的方法具有已经进行了光动力治疗（PDT）的癌细胞裂解物的DC。本发明的树突状细胞获得诱导抗肿瘤免疫应答的活性，从而发挥显着的抑制肿瘤生长的作用。

5. 发明申请

WO2008102937A1 MESENCHYMAL STEM CELL-MEDIATED AUTOLOGOUS DENDRITIC CELLS WITH INCREASED IMMUNOSUPPRESSION 审中-公开
标题翻译：间质干细胞介导的自体免疫细胞增殖免疫抑制
公开(公告)号：WO2008102937A1
公开(公告)日：2008-08-28
申请号：PCT/KR2007/003681
申请日：2007-07-31
申请人： CREAGENE INC. , LIM, Dae Seog , JEONG, Ju Ah , KANG, Mi-Sun , LEE, Hyun Soo , BAE, Yong Soo
发明人： LIM, Dae Seog , JEONG, Ju Ah , KANG, Mi-Sun , LEE, Hyun Soo , BAE, Yong Soo
IPC分类号： C12N5/06 , C12N5/08 , C12N5/00 , A61P37/02
CPC分类号： C12N5/064 , A61K2035/122 , C12N2502/1358
摘要： The present invention relates to a method for preparing dendritic cells which have an enhanced potential to suppress immune responses, dendritic cells carrying a potential to suppress immune responses, and a pharmaceutical composition comprising the dendritic cells capable of inducing immunosuppressive responses. The present dendritic cells having an enhanced potential to suppress immune responses can be utilized for treating various diseases or disorders through the suppression of immune responses. In addition, the enhanced immunotolerance potential of the dendritic cells of this invention ensures the cells to be effectively used as an immunosuppressive agent.
摘要翻译：本发明涉及一种制备树突细胞的方法，该方法具有增强的抑制免疫应答的潜力，具有抑制免疫应答潜力的树突状细胞，以及包含能诱导免疫抑制反应的树突状细胞的药物组合物。具有增强的抑制免疫应答潜力的本发明的树突状细胞可用于通过抑制免疫应答来治疗各种疾病或病症。此外，本发明的树突细胞的增强的免疫耐受潜力确保细胞被有效地用作免疫抑制剂。

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