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1. 发明申请

WO2010002418A2 QUICK-DISSOLVING ORAL THIN FILM FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS 审中-公开
标题翻译：快速溶解口服薄膜，用于靶向输送治疗药物
公开(公告)号：WO2010002418A2
公开(公告)日：2010-01-07
申请号：PCT/US2008/088300
申请日：2008-12-24
申请人： THE JOHNS HOPKINS UNIVERSITY , MAO, Hai-quan , YU, Christopher, Ku , TRUONG, Vu, Linh , LI, Yang , RANGARAJ, Dhanya , JIANG, Xuesong , SHAH, Sagar, Ramesh , SING, Derek, C.
发明人： MAO, Hai-quan , YU, Christopher, Ku , TRUONG, Vu, Linh , LI, Yang , RANGARAJ, Dhanya , JIANG, Xuesong , SHAH, Sagar, Ramesh , SING, Derek, C.
IPC分类号： A61K48/00 , A61K39/12
CPC分类号： A61K39/15 , A61K39/12 , A61K39/39 , A61K2039/542 , A61K2039/55555 , C12N2720/12334
摘要： This invention describes a quick-dissolving thin film strips comprising bioactive components encapsulated within pH-sensitive polymeric microparticles. The microparticles are embedded within the thin film and provide protection to components encapsulated within. The invention further describes methods to incorporate bioactive components encapsulated within pH-sensitive polymeric microparticles into a quick-dissolving thin film strip while maintaining the bioactivity of the contained therapeutic agents during thin film formation and microencapsulation.
摘要翻译：本发明描述了包含封装在pH敏感性聚合物微粒内的生物活性组分的快速溶解薄膜条。微粒嵌入在薄膜内并为封装在其中的组分提供保护。本发明进一步描述了将包封在pH敏感性聚合物微粒中的生物活性组分掺入快速溶解薄膜条中同时在薄膜形成和微胶囊化过程中保持所包含的治疗剂的生物活性的方法。

2. 发明申请

WO2010139092A1 BUTENE-BASED LIQUID CRYSTAL COMPOUNDS 审中-公开
标题翻译：基于液体的液体化合物
公开(公告)号：WO2010139092A1
公开(公告)日：2010-12-09
申请号：PCT/CN2009000622
申请日：2009-06-03
申请人： YANTAI VALIANT FINE CHEMICALS CO LTD , HU BAOHUA , YUAN HU , ZHOU YINBO , JIANG XUESONG , ZHANG TINGTING , FU HAICHAO , SONG XUEMING
发明人： HU BAOHUA , YUAN HU , ZHOU YINBO , JIANG XUESONG , ZHANG TINGTING , FU HAICHAO , SONG XUEMING
IPC分类号： C09K19/30 , C07C25/18
CPC分类号： C09K19/3048 , C09K2019/0407 , C09K2019/0444
摘要： The present invention discloses liquid crystal compounds of negative dielectric constant anisotropy useful as liquid crystal display materials, and mixed liquid crystal materials using such compounds. Such new nematic liquid crystal compounds are of negative dielectric constant anisotropy, the structures of which can be represented by the general formula (1); wherein, R1 represents hydrogen atom or a linear alkyl group having 1-8 carbon atoms or a linear alkenyl group having 2-8 carbon atoms, or R1 represents an alkoxy group or an alkenyloxy group formed by replacing one or two nonadjacent CH2 groups in the aforementioned linear alkyl or alkenyl group with oxygen atom, wherein 0-4 hydrogen atoms in the group may be substituted by fluorine; R2 represents hydrogen atom or a linear alkyl group having 1-8 carbon atoms, wherein 0-4 hydrogen atoms in the group may be substituted by fluorine; ring A represents phenylene or 1,4-cyclohexylene, 0-4 hydrogen atoms in the phenylene ring may be substituted by fluorine when ring A is phenylene; n represents 1-2, m represents 0-2.
摘要翻译：本发明公开了用作液晶显示材料的负介电常数各向异性的液晶化合物，以及使用这种化合物的混合液晶材料。这种新的向列型液晶化合物具有负介电常数各向异性，其结构可以由通式（1）表示; 其中，R1表示氢原子或具有1-8个碳原子的直链烷基或具有2-8个碳原子的直链烯基，或者R1表示通过在一个或多个取代基中替换一个或两个不相邻的CH2基而形成的烷氧基或烯氧基上述具有氧原子的直链烷基或烯基，其中所述基团中的0-4个氢原子可被氟取代; R2表示氢原子或具有1-8个碳原子的直链烷基，其中该基团中的0-4个氢原子可被氟取代; 环A表示亚苯基或1,4-亚环己基，当环A为亚苯基时，亚苯基环中0-4个氢原子可被氟取代; n表示1-2，m表示0-2。

3. 发明申请

WO2010002418A3 QUICK-DISSOLVING ORAL THIN FILM FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS 审中-公开
标题翻译：快速溶解口服薄膜用于定向递送治疗药物
公开(公告)号：WO2010002418A3
公开(公告)日：2010-08-12
申请号：PCT/US2008088300
申请日：2008-12-24
申请人： UNIV JOHNS HOPKINS , MAO HAI-QUAN , YU CHRISTOPHER KU , TRUONG VU LINH , LI YANG , RANGARAJ DHANYA , JIANG XUESONG , SHAH SAGAR RAMESH , SING DEREK C
发明人： MAO HAI-QUAN , YU CHRISTOPHER KU , TRUONG VU LINH , LI YANG , RANGARAJ DHANYA , JIANG XUESONG , SHAH SAGAR RAMESH , SING DEREK C
IPC分类号： A61K8/02
CPC分类号： A61K39/15 , A61K39/12 , A61K39/39 , A61K2039/542 , A61K2039/55555 , C12N2720/12334
摘要： This invention describes a quick-dissolving thin film strips comprising bioactive components encapsulated within pH-sensitive polymeric microparticles. The microparticles are embedded within the thin film and provide protection to components encapsulated within. The invention further describes methods to incorporate bioactive components encapsulated within pH-sensitive polymeric microparticles into a quick-dissolving thin film strip while maintaining the bioactivity of the contained therapeutic agents during thin film formation and microencapsulation.
摘要翻译：本发明描述了一种快速溶解的薄膜条，其包含封装在pH敏感的聚合物微粒内的生物活性成分。微粒被嵌入在薄膜内并为包封在其中的组分提供保护。本发明还描述了将包封在pH敏感性聚合物微粒内的生物活性成分并入快速溶解薄膜条中的方法，同时在薄膜形成和微胶囊化期间保持所含治疗剂的生物活性。

4. 发明申请

WO2006107692A1 APPARATUS AND METHOD FOR VIRTUALLY SHIELDING A SYNCHRONOUS SWITCHING REGULATOR 审中-公开
标题翻译：用于虚拟屏蔽同步开关稳压器的装置和方法
公开(公告)号：WO2006107692A1
公开(公告)日：2006-10-12
申请号：PCT/US2006/011603
申请日：2006-03-30
申请人： ANALOG DEVICES, INC. , JIANG, Xuesong
发明人： JIANG, Xuesong
IPC分类号： H02M1/00 , H02M3/156
CPC分类号： H02M7/003 , H02M3/158
摘要： Virtual shielding is used to reduce the sources/ origins of latchup and switching noise in a synchronous switching regulator. The regulator power stage may be split into two half stages. The ground bond wires of the half power stages may be positioned on opposite sides of the layout to substantially eliminate coupling between the ground bond wires. The power supply bond wire in one half power stage and the ground bond wire in the other half power stage may be positioned such that the mutual inductance between the power supply bond wire and the ground bond wire is maximized. The controller ground may be positioned substantially midway between the power supply bond wire in one half power stage and a respective ground bond wire in the other half power stage. The regulator controller may be placed between the regulator power stage and other analog circuitry to isolate the regulator power stage from the analog circuitry.
摘要翻译：虚拟屏蔽用于减少同步开关稳压器中闭锁和开关噪声的来源/来源。调节器功率级可以分为两个半级。半功率级的接地线可以位于布局的相对侧上，以基本上消除接地线之间的耦合。一半功率级的电源接合线和另一半功率级的接地线可以被定位成使得电源接合线和接地线之间的互感最大化。控制器接地可以位于一半功率级中的电源接合线和另一半功率级中的相应接地线之间的大致中间位置。调节器控制器可以放置在调节器功率级和其他模拟电路之间，以将调节器功率级与模拟电路隔离。

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