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    • 1. 发明申请
    • EDIBLE COMPOSITION FOR TREATING CUTANEOUS SIGNS OF AGEING
    • 用于处理老化迹象的食用组合物
    • WO2010094687A1
    • 2010-08-26
    • PCT/EP2010/051933
    • 2010-02-16
    • UNILEVER PLCUNILEVER N.V.HINDUSTAN UNILEVER LIMITEDCASEY, JohnJENKINS, GailWAINWRIGHT, Linda, Jane
    • CASEY, JohnJENKINS, GailWAINWRIGHT, Linda, Jane
    • A61K8/34A61K8/49A61K8/97A61Q19/08A23L1/30A61K8/02
    • A61K8/97A23L33/105A23V2002/00A61K8/02A61K8/345A61K8/49A61K8/498A61K2800/92A61Q19/08A23V2200/318A23V2250/21
    • This invention relates to the provision of an edible composition for the treatment of cutaneous signs of ageing, in particular those associated with loss of skin elasticity, wrinkles and sagging. Thus the inventive composition provides skin benefits selected from the group consisting of enhancing collagen deposition in the skin, reducing the appearance of wrinkles and reducing sagging. Thus the invention provides an edible composition for treating aged skin, the composition comprising: (a) 2 to 1000, preferably 5 to 750, most preferably 10 to 500 mg anthocyanidin and derivatives thereof; and (b) 1 to 20, preferably 5 to 15, most preferably 2 to 10 mg lutein and derivatives thereof; wherein the weight ratio of anthocyanidin to lutein is at least 1:1, preferably at least 10:1 and more preferably at least 25:1, even more preferably at least 50:1, most preferably at least 100:1; wherein the composition excludes copper in the form of separately or in combination copper gluconate and copper oxide; and further excludes separately or in combination with the copper exclusion Nandina domestica or an extract thereof. The invention also relates to a cosmetic method for providing the aforesaid skin benefits using the inventive composition.
    • 本发明涉及提供用于治疗皮肤老化症状的可食用组合物,特别是与皮肤弹性丧失,皱纹和下垂有关的那些。 因此,本发明的组合物提供了从增强皮肤中的胶原沉积,减少皱纹的外观和减少下垂的皮肤优点。 因此,本发明提供了一种用于治疗老化皮肤的可食用组合物,所述组合物包含:(a)2至1000,优选5至750,最优选10至500mg花色素及其衍生物; 和(b)1至20,优选5至15,最优选2至10mg叶黄素及其衍生物; 其中花青素与叶黄素的重量比为至少1:1,优选至少10:1,更优选至少25:1,甚至更优选至少50:1,最优选至少100:1; 其中所述组合物以单独或组合的葡萄糖酸铜和氧化铜的形式排除铜; 并且进一步排除或者与铜排除Nandina domestica或其提取物组合。 本发明还涉及使用本发明组合物提供上述皮肤益处的美容方法。
    • 5. 发明申请
    • ANTI-AGEING COMPOSITION
    • 抗老化组合物
    • WO2012163588A2
    • 2012-12-06
    • PCT/EP2012/056979
    • 2012-04-17
    • UNILEVER PLCUNILEVER N.V.HINDUSTAN UNILEVER LIMITEDFOWLER, Mark, IanJENKINS, GailWAINWRIGHT, Linda, Jane
    • FOWLER, Mark, IanJENKINS, GailWAINWRIGHT, Linda, Jane
    • A61K8/35A61K8/49A61K8/97A61Q19/08
    • A61K8/35A61K8/498A61K8/97A61K2800/92A61Q19/08
    • This invention relates to the provision of a topical or oral anti-ageing skin composition. Skin ageing, such as the appearance of fine lines, wrinkles or sagging, is a major age-related consumer issue. There is a continuing need for effective products to prevent or reduce the on-set of skin ageing. Thus in one aspect of the invention, a topical or oral composition for delaying the visible signs of skin ageing is provided, the composition comprising curcumin and a composition containing as its main component proanthocyanidin oligomer to which a substance having a phloroglucinol ring structure or resorcinol ring structure has been bonded, which is obtainable by heating plant materials comprising proanthocyanidin polymer or aqueous extract thereof comprising proanthocyanidin polymer, with a substance having a phloroglucinol ring structure or resorcinol ring structure in an acidic aqueous solution.
    • 本发明涉及提供局部或口服抗衰老皮肤组合物。 皮肤老化,如细纹,皱纹或下垂的外观,是与年龄相关的主要消费者问题。 持续需要有效的产品来预防或减少皮肤老化现象。 因此,在本发明的一个方面,提供了用于延缓皮肤老化的可见迹象的局部或口服组合物,该组合物包含姜黄素和含有作为其主要成分的原花色素寡聚物的组合物,其中具有间苯三酚环结构或间苯二酚环的物质 通过在含有原花色素聚合物的原花色素聚合物或其含水提取物的植物材料中加入具有间苯三酚环结构或间苯二酚环结构的物质在酸性水溶液中得到的结构。
    • 9. 发明申请
    • ANTI-AGEING COMPOSITION
    • 抗老化组合物
    • WO2012163588A3
    • 2013-06-13
    • PCT/EP2012056979
    • 2012-04-17
    • UNILEVER PLCUNILEVER NVUNILEVER HINDUSTANFOWLER MARK IANJENKINS GAILWAINWRIGHT LINDA JANE
    • FOWLER MARK IANJENKINS GAILWAINWRIGHT LINDA JANE
    • A61K8/35A61K8/49A61K8/97A61Q19/08
    • A61K8/35A61K8/498A61K8/97A61K2800/92A61Q19/08
    • This invention relates to the provision of a topical or oral anti-ageing skin composition. Skin ageing, such as the appearance of fine lines, wrinkles or sagging, is a major age-related consumer issue. There is a continuing need for effective products to prevent or reduce the on-set of skin ageing. Thus in one aspect of the invention, a topical or oral composition for delaying the visible signs of skin ageing is provided, the composition comprising curcumin and a composition containing as its main component proanthocyanidin oligomer to which a substance having a phloroglucinol ring structure or resorcinol ring structure has been bonded, which is obtainable by heating plant materials comprising proanthocyanidin polymer or aqueous extract thereof comprising proanthocyanidin polymer, with a substance having a phloroglucinol ring structure or resorcinol ring structure in an acidic aqueous solution.
    • 本发明涉及提供局部或口服抗衰老皮肤组合物。 皮肤老化,如细纹,皱纹或下垂的外观,是与年龄相关的主要消费者问题。 持续需要有效的产品来预防或减少皮肤老化现象。 因此,在本发明的一个方面,提供了用于延缓皮肤老化的可见迹象的局部或口服组合物,该组合物包含姜黄素和含有作为其主要成分的原花色素寡聚物的组合物,其中具有间苯三酚环结构或间苯二酚环的物质 通过在含有原花色素聚合物的原花色素聚合物或其含水提取物的植物材料中加入具有间苯三酚环结构或间苯二酚环结构的物质在酸性水溶液中得到的结构。
    • 10. 发明申请
    • ANTI-INFLAMMATORY COMPOSITION
    • 抗炎组合物
    • WO2012163590A1
    • 2012-12-06
    • PCT/EP2012/056981
    • 2012-04-17
    • UNILEVER PLCUNILEVER N.V.HINDUSTAN UNILEVER LIMITEDBARRETT, Karen, ElizabethJENKINS, GailLOTITO, Silvina, BeatrizWAINWRIGHT, Linda, Jane
    • BARRETT, Karen, ElizabethJENKINS, GailLOTITO, Silvina, BeatrizWAINWRIGHT, Linda, Jane
    • A61K45/06A61K31/353A61K31/7048
    • A61K36/63A61K31/353A61K31/7048A61K45/06A61K2300/00
    • This invention relates to the provision of an oral anti-inflammatory composition, in particular to an oral composition for the treatment or prevention of cardiovascular disease and the complications of hypertension through the identification of actives that down-regulate inflammatory markers, such as interleukin 6 (IL-6). Thus the invention provides an oral composition for preventing or treating cardiovascular disease or the complications of hypertension is provided, the composition comprising an aqueous ethanol extract of Olea europaea or oleuropein, and a composition containing as its main component proanthocyanidin oligomer to which a substance having a phloroglucinol ring structure or resorcinol ring structure has been bonded, which is obtainable by heating plant materials comprising proanthocyanidin polymer or aqueous extract thereof comprising proanthocyanidin polymer, with a substance having a phloroglucinol ring structure or resorcinol ring structure in an acidic aqueous solution. The invention also provides a method for preventing or treating cardiovascular disease or the complications of hypertension in a human being is provided, the method comprising the step of administering to a person in need therefor the composition of the invention.
    • 本发明涉及提供一种口服抗炎组合物,特别是口服组合物,用于治疗或预防心血管疾病和高血压的并发症,通过鉴定下调炎性标志物如白细胞介素6(IL- IL-6)。 因此,本发明提供了一种用于预防或治疗心血管疾病或口服高血压并发症的口服组合物,所述组合物包含欧莱碱或橄榄苦蛋白的含水乙醇提取物,以及含有作为其主要成分的原花色素寡聚物的组合物, 已经结合了间苯三酚环结构或间苯二酚环结构,其可通过在酸性水溶液中加热含有原花青素聚合物的植物材料或含有原花色素聚合物的水提取物与具有间苯三酚环结构或间苯二酚环结构的物质。 本发明还提供了一种用于预防或治疗心血管疾病或人类高血压并发症的方法,所述方法包括向需要的人施用本发明的组合物的步骤。