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    • 1. 发明申请
    • BIOCHEMICAL REACTIONS SYSTEM
    • 生化反应体系
    • WO2011124918A1
    • 2011-10-13
    • PCT/GB2011/050686
    • 2011-04-06
    • IT-IS INTERNATIONAL LIMITEDWEBSTER, Benjamin, MastermanHOWELL, James, Richard
    • WEBSTER, Benjamin, MastermanHOWELL, James, Richard
    • B01L7/00G01N21/64
    • B01L7/52B01L3/50851B01L3/50853B01L2300/046B01L2300/0654B01L2300/1822B01L2300/1827B01L2300/1894G01N21/0332G01N2201/0826G01N2201/0833
    • A chemical and/or biochemical system (1) having at least one reaction vessel (3) in which chemical and/or biochemical reactions may take place, the temperature of the reaction vessels being cycled between at least a highest predetermined temperature and a lowest predetermined temperature, the system comprising a thermal mount (4) for receiving the reaction vessel (s), the thermal mount being thermally coupled to a first, thermally conductive side of a thermoelectric module (5), a second thermally conductive side of the thermoelectric module being thermally coupled to a heat sink (6) and being provided with a pair of electrical contacts (33) to which a pair of electrically conductive wires (34) is connected for coupling to a power source, characterized in that a flexible adhesive (31, 32) is provided between the first thermally conductive side of the thermoelectric module and the thermal mount and between the second thermally conductive side of the thermoelectric module and the heat sink, whereby the adhesive is relatively thermally insulating compared to the first and second thermally conductive sides of the thermoelectric module and forms the sole coupling, thermal or mechanical, between the thermoelectric module and the thermal mount and between the thermoelectric module and the heat sink.
    • 化学和/或生化系统(1)具有至少一个其中可能发生化学和/或生物化学反应的反应容器(3),反应容器的温度在至少最高预定温度和最低预定温度之间循环 所述系统包括用于接收所述反应容器的热安装座(4),所述热安装件热耦合到热电模块(5)的第一导热侧,所述热电模块的第二导热侧 被热耦合到散热器(6)并且设置有一对电触点(33),一对导电线(34)连接到所述一对电触头(34)以耦合到电源,其特征在于,柔性粘合剂(31) ,32)设置在热电模块的第一导热侧和热座之间以及热电模块的第二导热侧之间,并且热sin k,由此与热电模块的第一和第二导热侧相比,粘合剂相对热绝缘,并且在热电模块和热安装座之间以及热电模块和散热器之间形成热耦合或机械的单独耦合。
    • 2. 发明申请
    • BIOCHEMICAL REACTION SYSTEM
    • 生化反应体系
    • WO2015150838A1
    • 2015-10-08
    • PCT/GB2015/051067
    • 2015-04-07
    • IT-IS INTERNATIONAL LIMITEDHOWELL, James RichardWEBSTER, Benjamin Masterman
    • HOWELL, James RichardWEBSTER, Benjamin Masterman
    • B01L7/00G01N21/25
    • B01L7/52B01L9/06B01L2300/02B01L2300/041B01L2300/0654B01L2300/0663B01L2300/0681B01L2300/0832B01L2300/087B01L2300/123B01L2300/1805B01L2300/1822B01L2300/1827G01N21/0332G01N21/272G01N2201/0231G01N2201/0846
    • A chemical and/or biochemical apparatus (10) for receiving a plurality of reaction vessels in which chemical and/or biochemical reactions may take place includes a thermal mount (14) having a plurality of wells (26) for receiving the reaction vessels (12), a thermal module (16) having a first side thermally coupled to the thermal mount (14), a first heat sink (18) thermally coupled to a second side of the thermal module, the heat sink (18) having a body and a plurality of thermally conductive fins (32) extending outwards from the body of the first heat sink (18), and a printed circuit board (54) having electronic components for controlling at least the thermal module (16), an excitation light source (62), and a light sensor (52). A first set of light waveguides (60) is provided for delivering excitation light to a reaction vessel, and a second set of light waveguides (38) is provided for receiving light from a reaction vessel and for delivering the light to the light sensor (52). The first heat sink (18) comprises an interior space (5) and the printed circuit board (54), the excitation light source (62), the light sensor (52) and the light waveguides (38, 60) are arranged within the interior space (5).
    • 用于接收可能发生化学和/或生物化学反应的多个反应容器的化学和/或生物化学装置(10)包括具有用于接收反应容器(12)的多个孔(26)的热安装件(14) ),具有热耦合到所述热座(14)的第一侧的热模块(16),热耦合到所述热模块的第二侧的第一散热器(18),所述散热器(18)具有主体和 从第一散热器(18)的主体向外延伸的多个导热翅片(32),以及具有用于至少控制热模块(16)的电子部件的印刷电路板(54),激发光源 62)和光传感器(52)。 提供第一组光波导(60)用于将激发光传送到反应容器,并且第二组光波导(38)被提供用于接收来自反应容器的光并将光传送到光传感器(52 )。 第一散热器(18)包括内部空间(5)和印刷电路板(54),激发光源(62),光传感器(52)和光波导(38,60)布置在 内部空间(5)。