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    • 1. 发明申请
    • SYSTEM AND METHOD FOR NEUROMODULATION
    • 神经修复的系统和方法
    • WO2013028274A3
    • 2014-07-17
    • PCT/US2012046329
    • 2012-07-11
    • INTERVENTIONAL AUTONOMICS CORPSANDERS WILLIAM EMASSON STEPHEN CRANSBURY TERRANCESTACK RICHARD S
    • SANDERS WILLIAM EMASSON STEPHEN CRANSBURY TERRANCESTACK RICHARD S
    • A61N1/36A61N1/05A61N1/08
    • A61N1/36114A61N1/0551A61N1/056A61N1/36053A61N1/36135A61N1/36139
    • A method of treating autonomic imbalance in a patient includes energizing a first therapeutic element disposed in a superior vena cava of the patient to deliver therapy to a parasympathetic nerve fiber such as a vagus nerve, and energizing a second therapeutic element disposed within the superior vena cava to deliver therapy to a sympathetic cardiac nerve fiber. A neuromodulation system includes a parasympathetic therapy element adapted for positioning within a blood vessel, a sympathetic therapy element adapted for positioning with the blood vessel; and a stimulator configured to energize the parasympathetic therapy element to deliver parasympathetic therapy to a parasympathetic nerve fiber disposed external to the blood vessel and energize the sympathetic therapy element within the blood vessel to deliver sympathetic therapy to a sympathetic nerve fiber disposed external to the blood vessel. Delivery of the parasympathetic and sympathetic therapy decreases the patient's heart rate and elevates or maintains the blood pressure of the patient.
    • 一种治疗患者自主性不平衡的方法包括激励设置在患者上腔静脉中的第一治疗元件,以将治疗递送至副交感神经纤维如迷走神经,以及激励位于上腔静脉内的第二治疗元件 为交感神经纤维提供治疗。 神经调节系统包括适于定位在血管内的副交感神经治疗元件,适于与血管定位的交感治疗元件; 以及刺激器,其构造成激励所述副交感神经治疗元件以将副交感神经治疗递送至设置在所述血管外部的副交感神经纤维,并且激励所述血管内的所述交感神经治疗元件,以向位于所述血管外部的交感神经纤维递送交感神经治疗 。 副交感神经和交感神经治疗的交付减少患者的心率,提高或维持患者的血压。