会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 7. 发明申请
    • FOCUSED INTERFERON IMMUNOTHERAPY
    • 聚焦干扰素免疫治疗
    • WO2017180764A1
    • 2017-10-19
    • PCT/US2017/027242
    • 2017-04-12
    • IMMUNGENE, INC.
    • GRESSER, MichaelKHARE, SanjaySTEWARD, Kristopher
    • C07K16/00C07K14/555
    • The present invention relates to methods of treating a proliferative disease (such as cancer) in an individual, comprising administering to the individual a non-naturally occurring fusion molecule comprising an antibody against one or more tumor-associated antigen ("TAA Ab") attached to an interferon (IFN) molecule (hereinafter "TAA Ab-IFN fusion molecule"), as monotherapy at therapeutically effective low doses, or in combination with immunotherapy, wherein the combination therapy provides increased effector cell killing. The methods of the present invention are particularly effective treating recurrent, resistant, or refractory proliferative diseases.
    • 本发明涉及治疗个体中增殖性疾病(例如癌症)的方法,其包括向个体施用包含针对一种或多种肿瘤相关的抗体的非天然存在的融合分子 作为治疗有效低剂量的单一疗法或与免疫疗法组合的抗原(“TAA Ab”)(下文称为“TAA Ab-IFN融合分子”),其中所述组合疗法提供增加的效应物 细胞杀伤。 本发明的方法特别有效地治疗复发性,耐药性或难治性增殖性疾病。