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1. 发明申请

WO2017023837A1 EMERGENT CARDIAC KIT AND DELIVERY DEVICE FOR TREATING MYOCARDIAL INFARCTION COMPLICATED BY ADVANCED HEART FAILURE 审中-公开
标题翻译：用于治疗由先心病失败所引起的心肌梗塞的急救心脏包装和输送装置
公开(公告)号：WO2017023837A1
公开(公告)日：2017-02-09
申请号：PCT/US2016/044967
申请日：2016-08-01
申请人： HUANG, Ming-He
发明人： HUANG, Ming-He
IPC分类号： A61M5/19 , A61K31/00 , A61P9/04 , A61P9/10
CPC分类号： A61M5/1407 , A61M5/19 , A61M5/34 , A61M25/0028
摘要： Provided herein are devices for concurrent intravenous infusion of multiple drugs. The device comprises a body with a syringe holding portion and a syringe driving portion, two or more syringes secured therein and a multi-lumen cather with a plurality of inlet channels and a single outlet channel. Also provided is a method for treating acute myocardial infarction complicated by advanced acute heart failure in a patient. Two or more drugs, such as a beta-blocker and a positive inotropic agent, in prefilled syringes are secured in the device and administered simultaneously into a single vein in a patient without the drugs mixing prior to administration. In addition, a kit is provided that comprises the device and syringes prefilled with a beta-blocker and the positive inotropic agent.
摘要翻译：本文提供用于并行静脉内输注多种药物的装置。该装置包括具有注射器保持部分和注射器驱动部分的主体，固定在其中的两个或更多个注射器和具有多个入口通道和单个出口通道的多腔引导器。还提供了一种治疗患者晚期急性心力衰竭并发并发急性心肌梗死的方法。预装的注射器中的两种或更多种药物，例如β-阻滞剂和正性肌力药物被固定在装置中，并且在施用之前同时施用于患者的单一静脉中，而不会使药物混合。另外，还提供了一个试剂盒，其中包括装置和预先填充有β-阻滞剂和正性肌力药剂的注射器。

2. 发明申请

WO2010144231A3 COMPOSITIONS AND METHODS FOR TREATING AIDS OR CANCER BY INHIBITING THE SECRETION OF MICROPARTICLES 审中-公开
标题翻译：通过抑制微生物分泌来治疗艾滋病或癌症的组合物和方法
公开(公告)号：WO2010144231A3
公开(公告)日：2011-04-21
申请号：PCT/US2010035698
申请日：2010-05-21
申请人： MOREHOUSE SCHOOL OF MEDICINE , BOND VINCENT CRAIG , POWELL MICHAEL , HUANG MING BO , ALI SYED , RAYMOND ANDREA D , SHELTON MARTIN NEVILLE , VILLINGER FRANCOIS JEAN
发明人： BOND VINCENT CRAIG , POWELL MICHAEL , HUANG MING BO , ALI SYED , RAYMOND ANDREA D , SHELTON MARTIN NEVILLE , VILLINGER FRANCOIS JEAN
IPC分类号： C07K7/08 , A61K38/17 , A61P31/18 , C07K14/435 , C12N15/63
CPC分类号： C07K7/08 , A61K38/00 , C07K7/06 , C07K14/005 , C12N2740/16033 , C12N2740/16322
摘要： Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.
摘要翻译：公开了抑制细胞释放微粒的新型肽。肽在N-末端含有至少一个VGFPV基序，长度为10-100个氨基酸。还公开了编码肽的多核苷酸，携带多核苷酸的表达载体，以及使用新肽治疗AIDS和肿瘤的方法。

3. 发明申请

WO1996002659A1 IT-62-B SUBSTANCE AND MEDICINAL COMPOSITION CONTAINING THE SAME 审中-公开
标题翻译： IT-62-B物质和药物组合物
公开(公告)号：WO1996002659A1
公开(公告)日：1996-02-01
申请号：PCT/JP1995001384
申请日：1995-07-12
申请人： TAIHO PHARMACEUTICAL CO., LTD. , KAWAUCHI, Takashi , SASAKI, Toru , MATSUMOTO, Hiroshi , OTANI, Toshio , CHEN, Ru-Xian , HUANG, Ming-Yu , YOSHIDA, Ken-ichiro
发明人： TAIHO PHARMACEUTICAL CO., LTD.
IPC分类号： C12P19/56
CPC分类号： C07H15/252 , C07H17/00 , C12P19/56
摘要： An IT-62-B substance represented by formula (1), a process for producing the same, a medicinal composition containing the same as the active ingredient, and a method of treating bacterium-induced infectious diseases and tumors by administering the same. The compound has antibacterial activities against gram-positive bacteria and part of gram-negative bacteria and also has an excellent antitumor activity against, for example, human nasopharyngeal cancer, thus being useful as a medicine.
摘要翻译：由式（1）表示的IT-62-B物质，其制备方法，含有该活性成分的药物组合物和通过施用该细菌诱导的传染病和肿瘤的方法。该化合物对革兰氏阳性细菌和革兰氏阴性细菌的一部分具有抗菌活性，并且对例如人鼻咽癌具有优异的抗肿瘤活性，因此可用作药物。

4. 发明申请

WO2019103692A1 LIGHT EMITTING GLASS STRUCTURE 审中-公开
公开(公告)号：WO2019103692A1
公开(公告)日：2019-05-31
申请号：PCT/SG2018/050564
申请日：2018-11-12
申请人： HUANG, Ming , KWANG, Philip Chwee-Seng
发明人： HUANG, Ming , KWANG, Philip Chwee-Seng
IPC分类号： H01L33/62 , H01L33/36 , H01L23/00
摘要： Disclosed herein is a light emitting glass structure comprising a first substrate, a first electrode layer formed over the first substrate, a interpose layer formed over the first electrode, and a second electrode layer formed on a second substrate for interposing the first substrate and the second substrate. The interpose layer comprises a light emitting material and a dielectric layer formed along the light emitting material, the first electrode layer and the second electrode layer for providing electrical connection for the light emitting glass structure.

5. 发明申请

WO2009152415A3 REDUCING MYOCARDIAL REPERFUSION INJURY BY THE COMBINATION THERAPY OF PROTEIN KINASE A ACTIVATION AND B1-ADRENERGIC RECEPTOR BLOCKADE 审中-公开
公开(公告)号：WO2009152415A3
公开(公告)日：2009-12-17
申请号：PCT/US2009/047181
申请日：2009-06-12
申请人： THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM , HUANG, Ming-He , FUJISE, Kenichi , URETSKY, Barry
发明人： HUANG, Ming-He , FUJISE, Kenichi , URETSKY, Barry
IPC分类号： A61K31/444 , A61K31/24 , A61K45/06 , A61P9/00
摘要： Embodiments of the invention are directed to methods of treating reperfusion or resuscitation injury in an individual in need of such treatment, comprising the step of administering to the individual who has had, having, or is at immediate risk of having an ischemic event an amount of a composition comprising a protein kinase A (PKA) activator and a β 1 -adrenergic receptor antagonist sufficient to reduce reperfusion injury to an ischemic tissue.

6. 发明申请

WO2018187391A1 MULTI-LAYER STRUCTURE AND METHOD OF MAKING SAME 审中-公开
公开(公告)号：WO2018187391A1
公开(公告)日：2018-10-11
申请号：PCT/US2018/025975
申请日：2018-04-04
申请人： CORNING INCORPORATED , CHAPARALA, Satish Chandra , ECKART, Kristen Lorraine , GERBER, Kurt Edward , HUANG, Ming-Huang , SHASHIDHAR, Nagaraja , SHENG, Huan-Hung , SORENSEN, Michael Lesley , SUBRAMANIAN, Ananthanarayanan
发明人： CHAPARALA, Satish Chandra , ECKART, Kristen Lorraine , GERBER, Kurt Edward , HUANG, Ming-Huang , SHASHIDHAR, Nagaraja , SHENG, Huan-Hung , SORENSEN, Michael Lesley , SUBRAMANIAN, Ananthanarayanan
IPC分类号： C03C15/00 , C03C21/00 , C03C23/00 , C03C27/06 , C03C27/10 , C03C27/12
摘要： A multi-layer and method of making the same are provided. The multi-layer, such as a sensor, can include a high strength glass overlay and a lamination layer on a substrate layer. The overlay can be less than 250 micrometers thick and have at least one tempered surface incorporating a surface compression layer of at least 5 micrometers deep and a surface compressive stress of at least 200 MPa. The overlay can exhibit a puncture factor of at least 3000 N/µm 2 at B10 (10 th percentile of the probability distribution of failure) in a multi-layer structure, an apparent thickness of less than 0.014 mm, and a pencil hardness greater than 6H. The method can include ion-exchange tempering at least one major surface of a glass sheet, light etching the major surface to remove flaws and laminating the glass sheet on the tempered and lightly etched major surface to a substrate layer.

7. 发明申请

WO2018089604A1 PARTICLE REDUCTION DURING SPUTTERING DEPOSITION 审中-公开
标题翻译：溅射沉积过程中的颗粒减少
公开(公告)号：WO2018089604A1
公开(公告)日：2018-05-17
申请号：PCT/US2017/060811
申请日：2017-11-09
申请人： CORNING INCORPORATED , COUILLARD, James, Gregory , HUANG, Ming-Huang
发明人： COUILLARD, James, Gregory , HUANG, Ming-Huang
IPC分类号： C23C14/50 , C23C14/56 , C03B35/20 , C03C17/00 , H01L21/67 , H01L21/68
摘要： Described herein are apparatuses and methods for holding a substrate in a position that minimizes particle contamination of the substrate when the substrate is being coated. Along with the apparatus, processes for reducing particle reduction on substrates are provided. The articles and processes described herein are useful in making coated glass substrates, such as used in electrochromic, photochromic, or photovoltaic technologies.
摘要翻译：这里描述的是用于在衬底被涂覆时将衬底保持在最小化衬底的颗粒污染的位置的装置和方法。与设备一起，提供了用于减少基材上的颗粒减少的方法。本文所述的制品和工艺可用于制造镀膜玻璃基材，例如用于电致变色，光致变色或光伏技术。

8. 发明申请

WO2013052058A1 ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开
标题翻译：抗微生物组合物及其使用方法
公开(公告)号：WO2013052058A1
公开(公告)日：2013-04-11
申请号：PCT/US2011/055219
申请日：2011-10-07
申请人： MOREHOUSE SCHOOL OF MEDICINE , BOND, Vincent, Craig , POWELL, Michael , HUANG, Ming, Bo , ALI, Syed , SHELTON, Martin, Neville
发明人： BOND, Vincent, Craig , POWELL, Michael , HUANG, Ming, Bo , ALI, Syed , SHELTON, Martin, Neville
IPC分类号： A61K38/10 , A61K38/16 , A61P31/04 , A61P31/00
CPC分类号： A61K38/10 , A61K38/08 , A61K38/16
摘要： The present application discloses a method for treating microbial infection using an antimicrobial composition comprises antimicrobial peptide which contains at least one VGFPV motif.
摘要翻译：本申请公开了一种使用抗微生物组合物治疗微生物感染的方法，其包含含有至少一种VGFPV基序的抗微生物肽。

9. 发明申请

WO2012162569A3 MAGNETOENCEPHALOGRAPHY SOURCE IMAGING 审中-公开
标题翻译：磁图形成像
公开(公告)号：WO2012162569A3
公开(公告)日：2013-01-24
申请号：PCT/US2012039478
申请日：2012-05-24
申请人： UNIV CALIFORNIA , HUANG MING-XIONG , LEE ROLAND R
发明人： HUANG MING-XIONG , LEE ROLAND R
IPC分类号： A61B5/0476 , A61B5/055 , G06F19/00
CPC分类号： A61B5/04008 , A61B5/04009 , A61B5/055 , A61B5/4076 , A61B5/7257 , G01R33/4806 , G01R33/4808 , G01R33/5602 , G01R33/56341 , G06F19/321
摘要： Techniques, devices and systems are disclosed for magnetoencephalography (MEG) source imaging. In one aspect, a method includes selecting signal data associated with one or more frequency bands from a spectrum of the signal data in the frequency domain, in which the signal data represents magnetic signals emitted by a brain of a subject and detected by a plurality of sensors outside the brain, defining locations of sources within the brain that generate the magnetic signals, in which the number of locations of the sources is selected to be greater than the number of sensors, and generating a source value of signal power based on the selected signal data corresponding to a respective location of the locations at the one or more frequencies.
摘要翻译：公开了用于脑电图（MEG）源成像的技术，装置和系统。在一个方面，一种方法包括从频域中的信号数据的频谱中选择与一个或多个频带相关联的信号数据，其中信号数据表示由对象的脑发射并由多个大脑外部的传感器，定义大脑内的源的位置，产生磁信号，其中源的位置数目选择为大于传感器的数量，并且基于所选择的信号产生信号功率的源值对应于在一个或多个频率处的位置的相应位置的信号数据。

10. 发明申请

WO2012162569A2 MAGNETOENCEPHALOGRAPHY SOURCE IMAGING 审中-公开
标题翻译：磁图形成像
公开(公告)号：WO2012162569A2
公开(公告)日：2012-11-29
申请号：PCT/US2012/039478
申请日：2012-05-24
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , HUANG, Ming-Xiong , LEE, Roland, R.
发明人： HUANG, Ming-Xiong , LEE, Roland, R.
IPC分类号： A61B5/0476 , A61B5/055 , G06F19/00
CPC分类号： A61B5/04008 , A61B5/04009 , A61B5/055 , A61B5/4076 , A61B5/7257 , G01R33/4806 , G01R33/4808 , G01R33/5602 , G01R33/56341 , G06F19/00 , G06F19/321
摘要： Techniques, devices and systems are disclosed for magnetoencephalography (MEG) source imaging. In one aspect, a method includes selecting signal data associated with one or more frequency bands from a spectrum of the signal data in the frequency domain, in which the signal data represents magnetic signals emitted by a brain of a subject and detected by a plurality of sensors outside the brain, defining locations of sources within the brain that generate the magnetic signals, in which the number of locations of the sources is selected to be greater than the number of sensors, and generating a source value of signal power based on the selected signal data corresponding to a respective location of the locations at the one or more frequencies.
摘要翻译：公开了用于脑电图（MEG）源成像的技术，装置和系统。在一个方面，一种方法包括从频域中的信号数据的频谱中选择与一个或多个频带相关联的信号数据，其中信号数据表示由对象的脑发射并由多个大脑外部的传感器，定义大脑内的源的位置，产生磁信号，其中源的位置数目选择为大于传感器的数量，并且基于所选择的信号产生信号功率的源值对应于在一个或多个频率处的位置的相应位置的信号数据。

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