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1. 发明申请

WO2006115464A1 SYSTEMS AND METHODS FOR PUMPING CONTINUOUS LIQUID COLUMNS USING HYDROPHOBICITY CONTROL FEATURES IN A MICROCHANNEL 审中-公开
标题翻译：在微通道中使用疏水控制特性来泵送连续液柱的系统和方法
公开(公告)号：WO2006115464A1
公开(公告)日：2006-11-02
申请号：PCT/SG2005/000130
申请日：2005-04-25
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , DHARMATILLEKE, Saman , HONG, Liu
发明人： DHARMATILLEKE, Saman , HONG, Liu
IPC分类号： B81B1/00 , F04B19/00
CPC分类号： F04B19/006 , B82Y30/00
摘要： A micropump includes a microchannel (10) formed in a substrate (15). The microchannel includes a plurality of electrode ring layers (25, 30) within the microchannel. Alternating electrode layers are covered with a fluoropolymer or other hydrophobic substance (20) that changes to hydrophilic in response to an applied voltage signal. Electrodes covered by fluoropolymer material (25) define hydrophobic regions interspersed between hydrophilic regions defined by exposed electrode ring layers (30). When a propagating fluid within the microchannel nears a hydrophobic region, a meniscus formed by the fluid is prevented from propagating due to the hydrophobic properties of the microchannel surface in that region. Application of a voltage to the hydrophobic region changes it to become hydrophilic, thereby allowing the meniscus, and the column of fluid behind it, to propagate past that region due to capillary forces. Upon encountering the next hydrophobic region, the meniscus is again prevented from propagating. Selective application of voltage signals to the electrodes in consecutive hydrophobic regions allows for a controlled rate of flow of fluid columns as determined by the dimensions of the microchannel (e.g., diameter of a microchannel having circular cross-section) and properties of the propagating fluid (e.g., viscosity).
摘要翻译：微型泵包括形成在基板（15）中的微通道（10）。微通道包括微通道内的多个电极环层（25,30）。交替电极层被含氟聚合物或其它疏水物质（20）覆盖，所述疏水物质（20）响应于施加的电压信号变为亲水的。由氟聚合物材料（25）覆盖的电极限定了疏散区域，其间分散在由暴露的电极环层（30）限定的亲水区域之间。当微通道内的传播流体靠近疏水区域时，由于该区域中的微通道表面的疏水特性，防止由流体形成的弯月面传播。向疏水区域施加电压使其变为亲水性，从而允许弯液面及其后面的流体柱由于毛细作用力而传播超过该区域。在遇到下一个疏水区域时，再次防止弯月面传播。在连续的疏水区域中选择性地向电极施加电压信号允许通过微通道的尺寸（例如，具有圆形横截面的微通道的直径）和传播流体的性质（例如，例如粘度）。

2. 发明申请

WO2009042539A1 LAMINATED FABRIC CONSTRUCTION WITH POLYOLEFIN COMPOSITIONS 审中-公开
标题翻译：具有聚烯烃组合物的层压织物结构
公开(公告)号：WO2009042539A1
公开(公告)日：2009-04-02
申请号：PCT/US2008/077189
申请日：2008-09-22
申请人： INVISTA TECHNOLOGIES S.AR.L. , COVELLI, Carmen, A. , FARMER, Douglas, K. , LAMBERT, James, M. , HONG, Liu , WALDBAUER, Robert, O. , NGUYEN, Young, D.
发明人： COVELLI, Carmen, A. , FARMER, Douglas, K. , LAMBERT, James, M. , HONG, Liu , WALDBAUER, Robert, O. , NGUYEN, Young, D.
IPC分类号： B32B27/32
CPC分类号： B32B27/32 , B32B3/266 , B32B5/18 , B32B5/245 , B32B7/12 , B32B27/065 , B32B27/08 , B32B2255/102 , B32B2255/26 , B32B2274/00 , B32B2437/00 , Y10T428/249991 , Y10T428/31938 , Y10T442/20 , Y10T442/2139
摘要： Articles comprising multiple layers are included. The multiple layer articles may include fabrics, foams, films, fiber in combination with a polyolefin composition such as a film, powder, or nonwoven.
摘要翻译：包括多层的物品。多层制品可以包括与聚烯烃组合物如膜，粉末或非织造材料组合的织物，泡沫，膜，纤维。

3. 发明申请

WO2006115464A8 SYSTEMS AND METHODS FOR PUMPING CONTINUOUS LIQUID COLUMNS USING HYDROPHOBICITY CONTROL FEATURES IN A MICROCHANNEL 审中-公开
标题翻译：使用微波通道中的疏水控制特性来泵送连续液柱的系统和方法
公开(公告)号：WO2006115464A8
公开(公告)日：2007-12-21
申请号：PCT/SG2005000130
申请日：2005-04-25
申请人： AGENCY SCIENCE TECH & RES , DHARMATILLEKE SAMAN , HONG LIU
发明人： DHARMATILLEKE SAMAN , HONG LIU
IPC分类号： B81B1/00 , F04B19/00
CPC分类号： F04B19/006 , B82Y30/00
摘要： A micropump includes a microchannel (10) formed in a substrate (15). The microchannel includes a plurality of electrode ring layers (25, 30) within the microchannel. Alternating electrode layers are covered with a fluoropolymer or other hydrophobic substance (20) that changes to hydrophilic in response to an applied voltage signal. Electrodes covered by fluoropolymer material (25) define hydrophobic regions interspersed between hydrophilic regions defined by exposed electrode ring layers (30). When a propagating fluid within the microchannel nears a hydrophobic region, a meniscus formed by the fluid is prevented from propagating due to the hydrophobic properties of the microchannel surface in that region. Application of a voltage to the hydrophobic region changes it to become hydrophilic, thereby allowing the meniscus, and the column of fluid behind it, to propagate past that region due to capillary forces. Upon encountering the next hydrophobic region, the meniscus is again prevented from propagating. Selective application of voltage signals to the electrodes in consecutive hydrophobic regions allows for a controlled rate of flow of fluid columns as determined by the dimensions of the microchannel (e.g., diameter of a microchannel having circular cross-section) and properties of the propagating fluid (e.g., viscosity).
摘要翻译：微型泵包括形成在基板（15）中的微通道（10）。微通道包括微通道内的多个电极环层（25,30）。交替电极层被含氟聚合物或其它疏水物质（20）覆盖，所述疏水性物质（20）响应于施加的电压信号变为亲水性。由氟聚合物材料（25）覆盖的电极限定了疏散区域，其间分散在由暴露的电极环层（30）限定的亲水区域之间。当微通道内的传播流体靠近疏水区域时，由于该区域中的微通道表面的疏水特性，防止由流体形成的弯液面传播。向疏水区域施加电压使其变为亲水性，从而允许弯液面及其后面的流体柱由于毛细作用力而传播超过该区域。在遇到下一个疏水区域时，再次防止弯月面传播。电压信号在连续的疏水区域中选择性地施加到电极允许通过微通道的尺寸（例如，具有圆形横截面的微通道的直径）和传播流体的性质（例如，例如粘度）。

4. 发明申请

WO2016115516A8 METHODS TO PREVENT OR TREAT PERIODONTITIS OR PERI-IMPLANTITIS 审中-公开
标题翻译：预防或治疗牙周炎或周围炎的方法
公开(公告)号：WO2016115516A8
公开(公告)日：2017-06-15
申请号：PCT/US2016013695
申请日：2016-01-15
申请人： UNIV IOWA RES FOUND , HONG LIU , AMENDT BRAD A , SALEM ALIASGER K , ELANGOVAN SATHEESH , ORTIZ GUSTAVO AVILA , SHARP THAD
发明人： HONG LIU , AMENDT BRAD A , SALEM ALIASGER K , ELANGOVAN SATHEESH , ORTIZ GUSTAVO AVILA , SHARP THAD
IPC分类号： C12N15/11 , C12N5/00
CPC分类号： C12N15/113 , C12N2310/141 , C12N2330/10
摘要： Compositions and methods to prevent, inhibit or treat aveolar or periodontal bone loss, enhance bone regeneration, prevent, inhibit or treat peri-implantitis or periodontitis, e.g., periodontitis or peri-implantitis associated with bone loss, or to prevent, inhibit or treat osteoarthritis are provided.
摘要翻译：预防，抑制或治疗牙槽骨或牙周骨损失的组合物和方法，增强骨再生，预防，抑制或治疗种植体周围炎或牙周炎，例如与骨质流失相关的牙周炎或种植体周围炎，或预防，抑制或治疗骨关节炎被提供。

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