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1. 发明申请

WO2004065511A3 LUMINESCENT DEVICE 审中-公开
公开(公告)号：WO2004065511A3
公开(公告)日：2004-08-05
申请号：PCT/GB2004/000229
申请日：2004-01-22
申请人： LUX BIOTECHNOLOGY LIMITED , HICKEY, Patrick, Colin
发明人： HICKEY, Patrick, Colin
IPC分类号： G21H3/02
摘要： The present invention provides a luminescent device (1) comprising a gaseous tritium light source (GTLS) (3). The GTLS (3) is held within a housing (2) which may optionally be located in an outer casing. A filter, such as a neutral density filter, may be used to modify the light output to predetermined levels. The device may be used to calibrate apparatus used to measure optical output, such as a luminometer.

2. 发明申请

WO2004076685A3 FUNGAL BIOSENSOR AND ASSAY 审中-公开
公开(公告)号：WO2004076685A3
公开(公告)日：2004-09-10
申请号：PCT/GB2004/000839
申请日：2004-03-01
申请人： LUX BIOTECHNOLOGY LIMITED , HICKEY, Patrick, Colin
发明人： HICKEY, Patrick, Colin
IPC分类号： C12Q1/02
摘要： A fungal biosensor comprising luminescent or fluorescent filamentous fungi is provided. The luminescence/fluorescence of the fungi varies depending upon whether the predetermined test substance is present or absent. Typically the gene encoding the luminescent or fluorescent protein is genetically engineered to be under the control of an inducible promoter or enhancer sensitive to the test substance. Suitable fungi include Neurospora Sp. , and Aspergillus Sp . Exemplary luminescent proteins include the Gaussia luciferase and the phosphoprotein obelin. An assay using the biosensor is also described.

3. 发明申请

WO2005030395A3 BIOCHIP 审中-公开
公开(公告)号：WO2005030395A3
公开(公告)日：2005-04-07
申请号：PCT/GB2004/004081
申请日：2004-09-24
申请人： LUX BIOTECHNOLOGY LIMITED , HICKEY, Patrick, Colin
发明人： HICKEY, Patrick, Colin
IPC分类号： B01L3/00
摘要： The invention relates to a biochip, comprising a substrate defining a plurality of fluid holding areas, there being fluid separating elements for preventing mixing of fluids held in said areas until the application of pressure to one or more said fluid.

4. 发明申请

WO2005030395A2 BIOCHIP 审中-公开
标题翻译：生物芯片
公开(公告)号：WO2005030395A2
公开(公告)日：2005-04-07
申请号：PCT/GB2004004081
申请日：2004-09-24
申请人： LUX BIOTECHNOLOGY LTD , HICKEY PATRICK COLIN
发明人： HICKEY PATRICK COLIN
IPC分类号： B01F13/00 , B01F15/02 , B01L3/00 , F04B19/24
CPC分类号： F04B19/24 , B01F13/0059 , B01F15/0205 , B01L3/50273 , B01L2300/14 , B01L2400/0442 , B01L2400/0454
摘要： The invention relates to a biochip, comprising a substrate defining a plurality of fluid holding areas, there being fluid separating elements for preventing mixing of fluids held in said areas until the application of pressure to one or more said fluid.
摘要翻译：本发明涉及生物芯片，其包括限定多个流体保持区域的基底，存在用于防止在所述区域中保持的流体混合的流体分离元件，直到对一个或多个所述流体施加压力。

5. 发明申请

WO2004076685A2 FUNGAL BIOSENSOR AND ASSAY 审中-公开
标题翻译：真菌生物传感器和测定
公开(公告)号：WO2004076685A2
公开(公告)日：2004-09-10
申请号：PCT/GB2004000839
申请日：2004-03-01
申请人： LUX BIOTECHNOLOGY LTD , HICKEY PATRICK COLIN
发明人： HICKEY PATRICK COLIN
IPC分类号： C12Q1/02 , C12Q1/66
CPC分类号： C12Q1/66 , G01N2333/37
摘要： A fungal biosensor comprising luminescent or fluorescent filamentous fungi is provided. The luminescence/fluorescence of the fungi varies depending upon whether the predetermined test substance is present or absent. Typically the gene encoding the luminescent or fluorescent protein is genetically engineered to be under the control of an inducible promoter or enhancer sensitive to the test substance. Suitable fungi include Neurospora Sp., and Aspergillus Sp. Exemplary luminescent proteins include the Gaussia luciferase and the phosphoprotein obelin. An assay using the biosensor is also described.
摘要翻译：提供包含发光或荧光丝状真菌的真菌生物传感器。真菌的发光/荧光根据预定的测试物质是否存在而变化。通常将编码发光或荧光蛋白的基因进行遗传工程改造以控制对受试物质敏感的诱导型启动子或增强子。合适的真菌包括脉孢菌属（Neurospora Sp。）和曲霉属（Aspergillus Sp。）。示例性的发光蛋白包括高斯萤光素酶和磷蛋白obelin。还描述了使用生物传感器的测定法。

6. 发明申请

WO2004065511A2 LUMINESCENT DEVICE 审中-公开
标题翻译：发光装置
公开(公告)号：WO2004065511A2
公开(公告)日：2004-08-05
申请号：PCT/GB2004000229
申请日：2004-01-22
申请人： LUX BIOTECHNOLOGY LTD , HICKEY PATRICK COLIN
发明人： HICKEY PATRICK COLIN
IPC分类号： C09K20060101 , C09K11/04 , G01J1/08 , G21H3/02 , H01J65/08 , C09K
CPC分类号： C09K11/04 , G01J1/08 , G21H3/02
摘要： The present invention provides a luminescent device (1) comprising a gaseous tritium light source (GTLS) (3). The GTLS (3) is held within a housing (2) which may optionally be located in an outer casing. A filter, such as a neutral density filter, may be used to modify the light output to predetermined levels. The device may be used to calibrate apparatus used to measure optical output, such as a luminometer.
摘要翻译：本发明提供一种包含气态氚光源（GTLS）（3）的发光装置（1）。 GTLS（3）被保持在可以可选地位于外壳中的壳体（2）内。可以使用诸如中性密度滤光器的滤光器将光输出修改为预定水平。该装置可用于校准用于测量光输出的装置，例如发光计。

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